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Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study.

To KK, Tsang OT, Leung WS, Tam AR, Wu TC, Lung DC, Yip CC, Cai JP, Chan JM, Chik TS, Lau DP, Choi CY, Chen LL, Chan WM, Chan KH, Ip JD, Ng AC, Poon RW, Luo CT, Cheng VC, Chan JF, Hung IF, Chen Z, Chen H, Yuen KY.

Lancet Infect Dis. 2020 Mar 23. pii: S1473-3099(20)30196-1. doi: 10.1016/S1473-3099(20)30196-1. [Epub ahead of print]


Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-polymerase chain reaction assay validated in vitro and with clinical specimens.

Chan JF, Yip CC, To KK, Tang TH, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tsoi HW, Choi GK, Tam AR, Cheng VC, Chan KH, Tsang OT, Yuen KY.

J Clin Microbiol. 2020 Mar 4. pii: JCM.00310-20. doi: 10.1128/JCM.00310-20. [Epub ahead of print]


Nanopore sequencing reveals novel targets for the diagnosis and surveillance of human and avian influenza A virus.

Yip CC, Chan WM, Ip JD, Seng CW, Leung KH, Poon RW, Ng AC, Wu WL, Zhao H, Chan KH, Siu GK, Ng TT, Cheng VC, Kok KH, Yuen KY, To KK.

J Clin Microbiol. 2020 Mar 4. pii: JCM.02127-19. doi: 10.1128/JCM.02127-19. [Epub ahead of print]


Escalating infection control response to the rapidly evolving epidemiology of the Coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong.

Cheng VCC, Wong SC, Chen JHK, Yip CCY, Chuang VWM, Tsang OTY, Sridhar S, Chan JFW, Ho PL, Yuen KY.

Infect Control Hosp Epidemiol. 2020 Mar 5:1-24. doi: 10.1017/ice.2020.58. [Epub ahead of print]


Consistent detection of 2019 novel coronavirus in saliva.

To KK, Tsang OT, Chik-Yan Yip C, Chan KH, Wu TC, Chan JMC, Leung WS, Chik TS, Choi CY, Kandamby DH, Lung DC, Tam AR, Poon RW, Fung AY, Hung IF, Cheng VC, Chan JF, Yuen KY.

Clin Infect Dis. 2020 Feb 12. pii: ciaa149. doi: 10.1093/cid/ciaa149. [Epub ahead of print]


A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.

Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J, Xing F, Liu J, Yip CC, Poon RW, Tsoi HW, Lo SK, Chan KH, Poon VK, Chan WM, Ip JD, Cai JP, Cheng VC, Chen H, Hui CK, Yuen KY.

Lancet. 2020 Feb 15;395(10223):514-523. doi: 10.1016/S0140-6736(20)30154-9. Epub 2020 Jan 24.


Preparedness and proactive infection control measures against the emerging novel coronavirus in China.

Cheng VCC, Wong SC, To KKW, Ho PL, Yuen KY.

J Hosp Infect. 2020 Mar;104(3):254-255. doi: 10.1016/j.jhin.2020.01.010. Epub 2020 Jan 18. No abstract available.


Transmission of rat hepatitis E virus infection to humans in Hong Kong: a clinical and epidemiological analysis.

Sridhar S, Yip CC, Wu S, Chew NF, Leung KH, Chan JF, Zhao PS, Chan WM, Poon RW, Tsoi HW, Cai JP, Chan HS, Leung AW, Tse CW, Zee JS, Tsang OT, Cheng VC, Lau SK, Woo PC, Tsang DN, Yuen KY.

Hepatology. 2020 Jan 20. doi: 10.1002/hep.31138. [Epub ahead of print]


Evaluation of RealStar® Alpha Herpesvirus PCR Kit for Detection of HSV-1, HSV-2, and VZV in Clinical Specimens.

Yip CCY, Sridhar S, Leung KH, Cheng AKW, Chan KH, Chan JFW, Cheng VCC, Yuen KY.

Biomed Res Int. 2019 Oct 9;2019:5715180. doi: 10.1155/2019/5715180. eCollection 2019.


Epidemiological and Clinical Characteristics of Human Hepegivirus 1 Infection in Patients With Hepatitis C.

Sridhar S, Yip CCY, Chew NFS, Wu S, Leung KH, Chan JFW, Cheng VCC, Yuen KY.

Open Forum Infect Dis. 2019 Jul 12;6(8):ofz329. doi: 10.1093/ofid/ofz329. eCollection 2019 Aug.


Measles outbreak from Hong Kong International Airport to the hospital due to secondary vaccine failure in healthcare workers.

Cheng VCC, Wong SC, Wong SCY, Sridhar S, Chen JHK, Yip CCY, Hung DLL, Li X, Chuang VWM, Tsang OTY, Woo GKS, Chuang SK, Yuen KY.

Infect Control Hosp Epidemiol. 2019 Dec;40(12):1407-1415. doi: 10.1017/ice.2019.278. Epub 2019 Oct 7.


Evaluation of disc diffusion tests and agar screening for predicting mecA-mediated oxacillin resistance in Staphylococcus lugdunensis revealed a cefoxitin-susceptible, mecA-positive S. lugdunensis clonal complex 27 clone.

Ho PL, Liu MC, Tong MK, Fan PM, Tse CW, Wu AK, Cheng VC, Chow KH.

J Glob Antimicrob Resist. 2020 Mar;20:260-265. doi: 10.1016/j.jgar.2019.08.021. Epub 2019 Sep 4.


Detection of norovirus in air samples in a non-vomiting patient: implications of testing saliva for norovirus in an immunocompromised host.

Cheng VCC, Wong SC, Chiu KHY, Yip CCY, Wong SCY, Yuen KY.

J Hosp Infect. 2019 Nov;103(3):357-358. doi: 10.1016/j.jhin.2019.07.011. Epub 2019 Jul 25. No abstract available.


Control of Carbapenemase-producing Enterobacteriaceae: Beyond the Hospital.

Cheng VCC, Wong SC, Wong SCY, Ho PL, Yuen KY.

EClinicalMedicine. 2019 Jan 7;6:3-4. doi: 10.1016/j.eclinm.2018.12.008. eCollection 2018 Dec. No abstract available.


Respiratory virus infection among hospitalized adult patients with or without clinically apparent respiratory infection: a prospective cohort study.

To KKW, Chan KH, Ho J, Pang PKP, Ho DTY, Chang ACH, Seng CW, Yip CCY, Cheng VCC, Hung IFN, Yuen KY.

Clin Microbiol Infect. 2019 Dec;25(12):1539-1545. doi: 10.1016/j.cmi.2019.04.012. Epub 2019 Apr 18.


Improving the specific diagnosis of trematode, cestode and nematode infections by a multiplex single-tube real-time PCR assay.

Wong SSY, Poon RWS, To KKW, Chan JFW, Lu G, Xing F, Cheng VCC, Yuen KY.

J Clin Pathol. 2019 Jul;72(7):487-492. doi: 10.1136/jclinpath-2018-205590. Epub 2019 Apr 5.


Structural and wetting properties of nature's finest silks (order Embioptera).

Stokes GY, DiCicco EN, Moore TJ, Cheng VC, Wheeler KY, Soghigian J, Barber RP Jr, Edgerly JS.

R Soc Open Sci. 2018 Sep 12;5(9):180893. doi: 10.1098/rsos.180893. eCollection 2018 Sep.


Donor-Derived Genotype 4 Hepatitis E Virus Infection, Hong Kong, China, 2018.

Sridhar S, Cheng VCC, Wong SC, Yip CCY, Wu S, Lo AWI, Leung KH, Mak WWN, Cai J, Li X, Chan JFW, Lau SKP, Woo PCY, Lai WM, Kwan TH, Au TWK, Lo CM, Wong SCY, Yuen KY.

Emerg Infect Dis. 2019 Mar;25(3):425-433. doi: 10.3201/eid2503.181563.


Reusable blood collection tube holders are implicated in nosocomial hepatitis C virus transmission.

Cheng VCC, Wong SC, Wong SCY, Sridhar S, Yip CCY, Chen JHK, Fung J, Chiu KHY, Ho PL, Chen S, Cheng BWC, Ho CL, Lo CM, Yuen KY.

Infect Control Hosp Epidemiol. 2019 Feb;40(2):252-253. doi: 10.1017/ice.2018.314. No abstract available.


Whole-genome sequencing data-based modeling for the investigation of an outbreak of community-associated methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit in Hong Kong.

Cheng VCC, Wong SC, Cao H, Chen JHK, So SYC, Wong SCY, Sridhar S, Yuen KY, Ho PL.

Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):563-573. doi: 10.1007/s10096-018-03458-y. Epub 2019 Jan 24.


Effectiveness of antimicrobial hospital curtains on reducing bacterial contamination-A multicenter study.

Luk S, Chow VCY, Yu KCH, Hsu EK, Tsang NC, Chuang VWM, Lai CKC, Hui M, Lee RA, Lai WM, Que TL, Fung SC, To WK, Cheng VCC, Wong ATY.

Infect Control Hosp Epidemiol. 2018 Dec 18:1-7. doi: 10.1017/ice.2018.315. [Epub ahead of print]


Directly observed hand hygiene - from healthcare workers to patients.

Cheng VCC, Wong SC, Wong SCY, Yuen KY.

J Hosp Infect. 2019 Apr;101(4):380-382. doi: 10.1016/j.jhin.2018.11.016. Epub 2018 Nov 27. No abstract available.


Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant.

Sridhar S, Yip CCY, Wu S, Cai J, Zhang AJ, Leung KH, Chung TWH, Chan JFW, Chan WM, Teng JLL, Au-Yeung RKH, Cheng VCC, Chen H, Lau SKP, Woo PCY, Xia NS, Lo CM, Yuen KY.

Emerg Infect Dis. 2018 Dec;24(12):2241-2250. doi: 10.3201/eid2412.180937.


Emergence of Cytomegalovirus Mononucleosis Syndrome Among Young Adults in Hong Kong Linked to Falling Seroprevalence: Results of a 14-Year Seroepidemiological Study.

Sridhar S, Chung TWH, Chan JFW, Cheng VCC, Lau SKP, Yuen KY, Woo PCY.

Open Forum Infect Dis. 2018 Oct 20;5(10):ofy262. doi: 10.1093/ofid/ofy262. eCollection 2018 Oct.


Idiopathic granulomatous mastitis: a 10-year study from a multicentre clinical database.

Co M, Cheng VCC, Wei J, Wong SCY, Chan SMS, Shek T, Kwong A.

Pathology. 2018 Dec;50(7):742-747. doi: 10.1016/j.pathol.2018.08.010. Epub 2018 Oct 30.


Occurrence of Highly Conjugative IncX3 Epidemic Plasmid Carrying bla NDM in Enterobacteriaceae Isolates in Geographically Widespread Areas.

Wang Y, Tong MK, Chow KH, Cheng VC, Tse CW, Wu AK, Lai RW, Luk WK, Tsang DN, Ho PL.

Front Microbiol. 2018 Sep 20;9:2272. doi: 10.3389/fmicb.2018.02272. eCollection 2018.


Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus.

Wong SSY, Yip CCY, Sridhar S, Leung KH, Cheng AKW, Fung AMY, Lam HY, Chan KH, Chan JFW, Cheng VCC, Tang BSF, Yuen KY.

Virol J. 2018 Sep 27;15(1):149. doi: 10.1186/s12985-018-1059-7.


Nosocomial transmission of hepatitis C virus in a liver transplant center in Hong Kong: implication of reusable blood collection tube holder as the vehicle for transmission.

Cheng VCC, Wong SC, Wong SCY, Sridhar S, Yip CCY, Chen JHK, Fung J, Chiu KHY, Ho PL, Chen S, Cheng BWC, Ho CL, Lo CM, Yuen KY.

Infect Control Hosp Epidemiol. 2018 Oct;39(10):1170-1177. doi: 10.1017/ice.2018.175. Epub 2018 Aug 29.


Mycobacterium chimaera-contaminated heater-cooler devices: the inner surface as the missing link?

Cheng VCC, Wong SC, Chen JHK, Wong SCY, Yuen KY.

J Hosp Infect. 2018 Nov;100(3):e157-e158. doi: 10.1016/j.jhin.2018.07.010. Epub 2018 Aug 6. No abstract available.


Saliva as a diagnostic specimen for testing respiratory virus by a point-of-care molecular assay: a diagnostic validity study.

To KKW, Yip CCY, Lai CYW, Wong CKH, Ho DTY, Pang PKP, Ng ACK, Leung KH, Poon RWS, Chan KH, Cheng VCC, Hung IFN, Yuen KY.

Clin Microbiol Infect. 2019 Mar;25(3):372-378. doi: 10.1016/j.cmi.2018.06.009. Epub 2018 Jun 12.


Environmental Panels as a Proxy for Nursing Facility Patients With Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus Colonization.

Cassone M, Mantey J, Perri MB, Gibson K, Lansing B, McNamara S, Patel PK, Cheng VCC, Walters MS, Stone ND, Zervos MJ, Mody L.

Clin Infect Dis. 2018 Aug 31;67(6):861-868. doi: 10.1093/cid/ciy115. Erratum in: Clin Infect Dis. 2018 Aug 31;67(6):987.


Novel selective medium for the isolation of corynebacterium kroppenstedtii from heavily colonised clinical specimens.

Wong SCY, Poon RWS, Foo CH, Ngan AHY, Tse H, Lam VCM, Leung THY, Wong CP, Cheng VCC, Chen JHK, Yuen KY.

J Clin Pathol. 2018 Sep;71(9):781-786. doi: 10.1136/jclinpath-2017-204834. Epub 2018 Mar 28.


Role of Hand Hygiene Ambassador and Implementation of Directly Observed Hand Hygiene Among Residents in Residential Care Homes for the Elderly in Hong Kong.

Cheng VCC, Chen H, Wong SC, Chen JHK, Ng WC, So SYC, Chan TC, Wong SCY, Ho PL, Mody L, Chan FHW, Wong ATY, Yuen KY.

Infect Control Hosp Epidemiol. 2018 May;39(5):571-577. doi: 10.1017/ice.2018.21. Epub 2018 Feb 27.


Impact of inter-genotypic recombination and probe cross-reactivity on the performance of the Abbott RealTime HCV Genotype II assay for hepatitis C genotyping.

Sridhar S, Yip CCY, Chan JFW, To KKW, Cheng VCC, Yuen KY.

Diagn Microbiol Infect Dis. 2018 May;91(1):34-37. doi: 10.1016/j.diagmicrobio.2017.12.024. Epub 2018 Jan 11.


Evaluation of the molecular Xpert Xpress Flu/RSV assay vs. Alere i Influenza A & B assay for rapid detection of influenza viruses.

Chen JH, Lam HY, Yip CC, Cheng VC, Chan JF, Leung TH, Sridhar S, Chan KH, Tang BS, Yuen KY.

Diagn Microbiol Infect Dis. 2018 Mar;90(3):177-180. doi: 10.1016/j.diagmicrobio.2017.11.010. Epub 2017 Nov 24.


Rapid Detection of Carbapenemase Production in Enterobacteriaceae by Use of a Modified Paper Strip Carba NP Method.

Ho PL, Wang Y, Wing-Sze Tse C, Fung KS, Cheng VC, Lee R, To WK, Lai RW, Luk WK, Que TL, Tsang DN.

J Clin Microbiol. 2017 Dec 26;56(1). pii: e01110-17. doi: 10.1128/JCM.01110-17. Print 2018 Jan.


Japanese Encephalitis Virus Transmitted Via Blood Transfusion, Hong Kong, China.

Cheng VCC, Sridhar S, Wong SC, Wong SCY, Chan JFW, Yip CCY, Chau CH, Au TWK, Hwang YY, Yau CSW, Lo JYC, Lee CK, Yuen KY.

Emerg Infect Dis. 2018 Jan;24(1). doi: 10.3201/eid2401.171297. Epub 2018 Jan 17.


Control of multidrug-resistant Acinetobacter baumannii in Hong Kong: Role of environmental surveillance in communal areas after a hospital outbreak.

Cheng VCC, Wong SC, Chen JHK, So SYC, Wong SCY, Ho PL, Yuen KY.

Am J Infect Control. 2018 Jan;46(1):60-66. doi: 10.1016/j.ajic.2017.07.010. Epub 2017 Sep 8.


Molecular identification of cestodes and nematodes by cox1 gene real-time PCR and sequencing.

Poon RWS, Tam EWT, Lau SKP, Cheng VCC, Yuen KY, Schuster RK, Woo PCY.

Diagn Microbiol Infect Dis. 2017 Nov;89(3):185-190. doi: 10.1016/j.diagmicrobio.2017.07.012. Epub 2017 Jul 29.


Rapid Differentiation of Haemophilus influenzae and Haemophilus haemolyticus by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry with ClinProTools Mass Spectrum Analysis.

Chen JHK, Cheng VCC, Wong CP, Wong SCY, Yam WC, Yuen KY.

J Clin Microbiol. 2017 Sep;55(9):2679-2685. doi: 10.1128/JCM.00267-17. Epub 2017 Jun 21.


First Report of a Fatal Case Associated with EV-D68 Infection in Hong Kong and Emergence of an Interclade Recombinant in China Revealed by Genome Analysis.

Yip CCY, Lo JYC, Sridhar S, Lung DC, Luk S, Chan KH, Chan JFW, Cheng VCC, Woo PCY, Yuen KY, Lau SKP.

Int J Mol Sci. 2017 May 16;18(5). pii: E1065. doi: 10.3390/ijms18051065.


Comparative evaluation of a laboratory developed real-time PCR assay and the RealStar® HHV-6 PCR Kit for quantitative detection of human herpesvirus 6.

Yip CCY, Sridhar S, Cheng AKW, Fung AMY, Cheng VCC, Chan KH, Yuen KY.

J Virol Methods. 2017 Aug;246:112-116. doi: 10.1016/j.jviromet.2017.05.001. Epub 2017 May 2.


From SARS to Avian Influenza Preparedness in Hong Kong.

Wong ATY, Chen H, Liu SH, Hsu EK, Luk KS, Lai CKC, Chan RFY, Tsang OTY, Choi KW, Kwan YW, Tong AYH, Cheng VCC, Tsang DNC; Central Committee on Infectious Diseases and Emergency Response, Hospital Authority, Hong Kong Special Administrative Region.

Clin Infect Dis. 2017 May 15;64(suppl_2):S98-S104. doi: 10.1093/cid/cix123.


Seasonal Outbreak of Bacillus Bacteremia Associated With Contaminated Linen in Hong Kong.

Cheng VCC, Chen JHK, Leung SSM, So SYC, Wong SC, Wong SCY, Tse H, Yuen KY.

Clin Infect Dis. 2017 May 15;64(suppl_2):S91-S97. doi: 10.1093/cid/cix044.


The challenge of patient empowerment in hand hygiene promotion in health care facilities in Hong Kong.

Cheng VCC, Wong SC, Wong IWY, Chau PH, So SYC, Wong SCY, Chen JHK, Lee WM, Tai JWM, Chau CH, Lo WK, Yuen KY.

Am J Infect Control. 2017 May 1;45(5):562-565. doi: 10.1016/j.ajic.2016.12.007. Epub 2017 Jan 25.


Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection: An Open-label Randomized, Controlled, Phase IIb/III Trial.

Hung IFN, To KKW, Chan JFW, Cheng VCC, Liu KSH, Tam A, Chan TC, Zhang AJ, Li P, Wong TL, Zhang R, Cheung MKS, Leung W, Lau JYN, Fok M, Chen H, Chan KH, Yuen KY.

Chest. 2017 May;151(5):1069-1080. doi: 10.1016/j.chest.2016.11.012. Epub 2016 Nov 22.


Application of a dual target PCR-high resolution melting (HRM) method for rapid nontuberculous mycobacteria identification.

Chen JH, Cheng VC, She KK, Yam WC, Yuen KY.

J Microbiol Methods. 2017 Jan;132:1-3. doi: 10.1016/j.mimet.2016.11.004. Epub 2016 Nov 9.


Epidemiology and Clinical Characteristics of Acinetobacter Peritoneal Dialysis-Related Peritonitis in Hong Kong-With a Perspective on Multi-Drug and Carbapenem Resistance.

Li PH, Cheng VC, Yip T, Yap DY, Lui SL, Lo WK.

Perit Dial Int. 2017 Mar-Apr;37(2):177-182. doi: 10.3747/pdi.2016.00123. Epub 2016 Sep 28.


A Novel Risk Factor Associated With Colonization by Carbapenemase-Producing Enterobacteriaceae: Use of Proton Pump Inhibitors in Addition to Antimicrobial Treatment.

Cheng VC, Chen JH, So SY, Wong SC, Chau PH, Wong LM, Ching RH, Ng MM, Lee WM, Hung IF, Ho PL, Yuen KY.

Infect Control Hosp Epidemiol. 2016 Dec;37(12):1418-1425. Epub 2016 Sep 13.


IncN ST7 epidemic plasmid carrying blaIMP-4 in Enterobacteriaceae isolates with epidemiological links to multiple geographical areas in China.

Wang Y, Lo WU, Lai RW, Tse CW, Lee RA, Luk WK, Cheng VC, Que TL, Chow KH, Ho PL.

J Antimicrob Chemother. 2017 Jan;72(1):99-103. Epub 2016 Sep 8.


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