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A preliminary report of head-to-head comparison of 18-gene-based clinical-genomic model and oncotype DX 21-gene assay for predicting recurrence of early-stage breast cancer.

Yang PS, Lee YH, Chung CF, Chang YC, Wang MY, Lo C, Tsai LW, Shih KH, Lei J, Yu BL, Cheng SH, Huang CS.

Jpn J Clin Oncol. 2019 Jul 9. pii: hyz102. doi: 10.1093/jjco/hyz102. [Epub ahead of print]


Topologic Analysis of Plasma Mitochondrial DNA Reveals the Coexistence of Both Linear and Circular Molecules.

Ma ML, Zhang H, Jiang P, Sin STK, Lam WKJ, Cheng SH, Lee WS, Gai W, Tse OYO, Peng W, Wong J, Raghupathy R, Wong RSM, Sahota D, Leung TY, Chan KCA, Chiu RWK, Lo YMD.

Clin Chem. 2019 Jul 1. pii: clinchem.2019.308122. doi: 10.1373/clinchem.2019.308122. [Epub ahead of print]


Sparse Sampling of Silence Type I Errors With an Emphasis on Primary Auditory Cortex.

Manno FAM, Fernandez-Ruiz J, Manno SHC, Cheng SH, Lau C, Barrios FA.

Front Neurosci. 2019 May 31;13:516. doi: 10.3389/fnins.2019.00516. eCollection 2019.


Substrate Reduction Therapy for Sandhoff Disease through Inhibition of Glucosylceramide Synthase Activity.

Marshall J, Nietupski JB, Park H, Cao J, Bangari DS, Silvescu C, Wilper T, Randall K, Tietz D, Wang B, Ying X, Leonard JP, Cheng SH.

Mol Ther. 2019 Jun 4. pii: S1525-0016(19)30265-5. doi: 10.1016/j.ymthe.2019.05.018. [Epub ahead of print]


Nationwide surveillance of antimicrobial resistance among clinically important Gram-negative bacteria with an emphasis on carbapenems and colistin: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) in 2018.

Lee YL, Lu MC, Shao PL, Lu PL, Chen YH, Cheng SH, Ko WC, Lin CY, Wu TS, Yen MY, Wang LS, Liu CP, Lee WS, Shi ZY, Chen YS, Wang FD, Tseng SH, Lin CN, Chen YH, Sheng WH, Lee CM, Liao MH, Hsueh PR.

Int J Antimicrob Agents. 2019 Jun 13. pii: S0924-8579(19)30162-1. doi: 10.1016/j.ijantimicag.2019.06.009. [Epub ahead of print]


Escalating utilization of inpatient surgery for pelvic floor dysfunction in the elderly in Taiwan.

Ng SC, Chen CC, Cheng SH, Chen GD.

Neurourol Urodyn. 2019 May 29. doi: 10.1002/nau.24046. [Epub ahead of print]


Grazoprevir/elbasvir in peginterferon alfa plus ribavirin experienced patients with chronic genotype 1 HCV/HIV co-infection: a non-randomized, open-label clinical trial.

Lin YC, Li SW, Ku SY, Hsieh HT, Lin MH, Chang SY, Wu WW, Sun NL, Cheng SH, Cheng CY.

Infect Drug Resist. 2019 Apr 18;12:937-945. doi: 10.2147/IDR.S206938. eCollection 2019.


Prevalence and impact of clinical violence towards nursing students in Hong Kong: a cross-sectional study.

Cheung K, Ching SS, Cheng SHN, Ho SSM.

BMJ Open. 2019 May 16;9(5):e027385. doi: 10.1136/bmjopen-2018-027385.


UMP Kinase Regulates Chloroplast Development and Cold Response in Rice.

Dong Q, Zhang YX, Zhou Q, Liu QE, Chen DB, Wang H, Cheng SH, Cao LY, Shen XH.

Int J Mol Sci. 2019 Apr 29;20(9). pii: E2107. doi: 10.3390/ijms20092107.


Identifying occult maternal malignancies from 1.93 million pregnant women undergoing noninvasive prenatal screening tests.

Ji X, Li J, Huang Y, Sung PL, Yuan Y, Liu Q, Chen Y, Ju J, Zhou Y, Huang S, Chen F, Han Y, Yuan W, Fan C, Zhao Q, Wu H, Feng S, Liu W, Li Z, Chen J, Chen M, Yao H, Zeng L, Ma T, Fan S, Zhang J, Yuen KY, Cheng SH, Chik IWS, Liu NT, Zhu J, Lin S, Cao J, Tong S, Shan Z, Li W, Hekmat MR, Garshasbi M, Suela J, Torres Y, Cigudosa JC, Ruiz FJP, Rodríguez L, García M, Bernik J, Traven E, Reš U, Tul N, Tseng CF, Zhao D, Sun L, Pan Q, Shen L, Dai M, Wang Y, Wang J, Yang H, Yin Y, Duan T, Zhu B, Choolani M, Jin X, Chen Y, Mao M.

Genet Med. 2019 Apr 12. doi: 10.1038/s41436-019-0510-5. [Epub ahead of print]


Early Stage Alterations in White Matter and Decreased Functional Interhemispheric Hippocampal Connectivity in the 3xTg Mouse Model of Alzheimer's Disease.

Manno FAM, Isla AG, Manno SHC, Ahmed I, Cheng SH, Barrios FA, Lau C.

Front Aging Neurosci. 2019 Mar 22;11:39. doi: 10.3389/fnagi.2019.00039. eCollection 2019.


In Vivo Imaging of Small Molecular Weight Peptides for Targeted Renal Drug Delivery: A Study in Normal and Polycystic Kidney Diseased Mice.

Lenhard S, McAlexander A, Virtue A, Fieles W, Skedzielewski T, Rambo M, Trinh H, Cheng SH, Hong H, Isidro-Llobet A, Nadin A, Geske R, Klein JL, Lee D, Jucker BM, Hu E.

J Pharmacol Exp Ther. 2019 Apr 1. pii: jpet.119.257022. doi: 10.1124/jpet.119.257022. [Epub ahead of print]


Excessive inflammation impairs heart regeneration in zebrafish breakdance mutant after cryoinjury.

Xu S, Liu C, Xie F, Tian L, Manno SH, Manno FAM 3rd, Fallah S, Pelster B, Tse G, Cheng SH.

Fish Shellfish Immunol. 2019 Jun;89:117-126. doi: 10.1016/j.fsi.2019.03.058. Epub 2019 Mar 27.


Unresectable pancreatic ductal adenocarcinoma: Role of CT quantitative imaging biomarkers for predicting outcomes of patients treated with chemotherapy.

Cheng SH, Cheng YJ, Jin ZY, Xue HD.

Eur J Radiol. 2019 Apr;113:188-197. doi: 10.1016/j.ejrad.2019.02.009. Epub 2019 Feb 11.


Microwave-Synthesized Platinum-Embedded Mesoporous Silica Nanoparticles as Dual-Modality Contrast Agents: Computed Tomography and Optical Imaging.

Chu CH, Cheng SH, Chen NT, Liao WN, Lo LW.

Int J Mol Sci. 2019 Mar 28;20(7). pii: E1560. doi: 10.3390/ijms20071560.


[The characteristics of recent HIV-1 infection and associated factors in Tianjin].

Ning TL, Guo Y, Zheng MN, Bai JY, Zhao X, Zhou N, Gong H, Cheng SH.

Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Mar 6;53(3):323-326. doi: 10.3760/cma.j.issn.0253-9624.2019.03.017. Chinese.


Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin.

Sun K, Jiang P, Cheng SH, Cheng THT, Wong J, Wong VWS, Ng SSM, Ma BBY, Leung TY, Chan SL, Mok TSK, Lai PBS, Chan HLY, Sun H, Chan KCA, Chiu RWK, Lo YMD.

Genome Res. 2019 Mar;29(3):418-427. doi: 10.1101/gr.242719.118.


Tailored high cycling performance in a solid polymer electrolyte with perovskite-type Li0.33La0.557TiO3 nanofibers for all-solid-state lithium ion batteries.

He KQ, Zha JW, Du P, Cheng SH, Liu C, Dang ZM, Li RKY.

Dalton Trans. 2019 Mar 14;48(10):3263-3269. doi: 10.1039/c9dt00074g. Epub 2019 Feb 18.


A community pharmacist home visit project for high utilizers under a universal health system: A preliminary assessment.

Huang YY, Cheng SH.

Health Policy. 2019 Apr;123(4):373-378. doi: 10.1016/j.healthpol.2019.01.011. Epub 2019 Jan 30.


Delta-like 1 homologue promotes tumorigenesis and epithelial-mesenchymal transition of ovarian high-grade serous carcinoma through activation of Notch signaling.

Huang CC, Cheng SH, Wu CH, Li WY, Wang JS, Kung ML, Chu TH, Huang ST, Feng CT, Huang SC, Tai MH.

Oncogene. 2019 Apr;38(17):3201-3215. doi: 10.1038/s41388-018-0658-5. Epub 2019 Jan 9.


Early Seroreversion After 2 Doses of Hepatitis A Vaccination in Human Immunodeficiency Virus-Positive Patients: Incidence and Associated Factors.

Huang SH, Huang CH, Wang NC, Chen TC, Lee YT, Lin SP, Lin TY, Lin CY, Lee YL, Lee CH, Chen CP, Lin KY, Chen GJ, Liu CE, Cheng SH, Lu PL, Yang CJ, Hung CC; Taiwan HIV Study Group.

Hepatology. 2019 Jan 7. doi: 10.1002/hep.30495. [Epub ahead of print]


Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA.

Serpas L, Chan RWY, Jiang P, Ni M, Sun K, Rashidfarrokhi A, Soni C, Sisirak V, Lee WS, Cheng SH, Peng W, Chan KCA, Chiu RWK, Reizis B, Lo YMD.

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):641-649. doi: 10.1073/pnas.1815031116. Epub 2018 Dec 28.


Enrichment of fetal and maternal long cell-free DNA fragments from maternal plasma following DNA repair.

Vong JSL, Jiang P, Cheng SH, Lee WS, Tsang JCH, Leung TY, Chan KCA, Chiu RWK, Lo YMD.

Prenat Diagn. 2019 Jan;39(2):88-99. doi: 10.1002/pd.5406. Epub 2019 Jan 10.


Quantification of Beat-To-Beat Variability of Action Potential Durations in Langendorff-Perfused Mouse Hearts.

Tse G, Du Y, Hao G, Li KHC, Chan FYW, Liu T, Li G, Bazoukis G, Letsas KP, Wu WKK, Cheng SH, Wong WT.

Front Physiol. 2018 Nov 27;9:1578. doi: 10.3389/fphys.2018.01578. eCollection 2018.


High-throughput brain activity mapping and machine learning as a foundation for systems neuropharmacology.

Lin X, Duan X, Jacobs C, Ullmann J, Chan CY, Chen S, Cheng SH, Zhao WN, Poduri A, Wang X, Haggarty SJ, Shi P.

Nat Commun. 2018 Dec 3;9(1):5142. doi: 10.1038/s41467-018-07289-5.


[Study on acute HIV-1 infection in men who have sex with men in Tianjin].

Ning TL, Zheng MN, Li L, Bai JY, Zhao X, Guo Y, Du XR, Cheng SH.

Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Nov 10;39(11):1472-1476. doi: 10.3760/cma.j.issn.0254-6450.2018.11.010. Chinese.


Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma.

Jiang P, Sun K, Tong YK, Cheng SH, Cheng THT, Heung MMS, Wong J, Wong VWS, Chan HLY, Chan KCA, Lo YMD, Chiu RWK.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10925-E10933. doi: 10.1073/pnas.1814616115. Epub 2018 Oct 29.


Evaluation of cost-effectiveness of peginterferon plus ribavirin for chronic hepatitis C treatment and direct-acting antiviral agents among HIV-infected patients in the prison and community settings.

Chen CP, Cheng CY, Zou H, Cheng CH, Cheng SH, Chen CK, Chen CH, Bair MJ.

J Microbiol Immunol Infect. 2018 Oct 12. pii: S1684-1182(18)30123-3. doi: 10.1016/j.jmii.2018.10.002. [Epub ahead of print]


Molecular insights into the mechanism and the efficiency-structure relationship of phosphorus removal by coagulation.

Chu YB, Li M, Liu JW, Xu W, Cheng SH, Zhao HZ.

Water Res. 2018 Dec 15;147:195-203. doi: 10.1016/j.watres.2018.10.006. Epub 2018 Oct 5.


Assessing quality of primary diabetes care in South Korea and Taiwan using avoidable hospitalizations.

Kim H, Cheng SH.

Health Policy. 2018 Nov;122(11):1222-1231. doi: 10.1016/j.healthpol.2018.09.009. Epub 2018 Sep 18. Review.


Chlorambucil-conjugated platinum(IV) prodrugs to treat triple-negative breast cancer in vitro and in vivo.

Ma ZY, Wang DB, Song XQ, Wu YG, Chen Q, Zhao CL, Li JY, Cheng SH, Xu JY.

Eur J Med Chem. 2018 Sep 5;157:1292-1299. doi: 10.1016/j.ejmech.2018.08.065. Epub 2018 Aug 27.


Spectroscopic examination of enamel staining by coffee indicates dentin erosion by sequestration of elements.

Manno SHC, Manno FAM, Ahmed I, Ahmed R, Shu L, Li L, Xu S, Xie F, Li VW, Ho J, Cheng SH, Lau C.

Talanta. 2018 Nov 1;189:550-559. doi: 10.1016/j.talanta.2018.07.032. Epub 2018 Jul 20.


Inhibiting neutral amino acid transport for the treatment of phenylketonuria.

Belanger AM, Przybylska M, Gefteas E, Furgerson M, Geller S, Kloss A, Cheng SH, Zhu Y, Yew NS.

JCI Insight. 2018 Jul 26;3(14). pii: 121762. doi: 10.1172/jci.insight.121762. eCollection 2018 Jul 26.


Rare cause for a common presentation: isolated pulmonary valve endocarditis yet another mimicker.

Reza AS, Anand D, Cheng SH, Anand D.

BMJ Case Rep. 2018 Jul 18;2018. pii: bcr-2018-224703. doi: 10.1136/bcr-2018-224703.


Fetal gene therapy for neurodegenerative disease of infants.

Massaro G, Mattar CNZ, Wong AMS, Sirka E, Buckley SMK, Herbert BR, Karlsson S, Perocheau DP, Burke D, Heales S, Richard-Londt A, Brandner S, Huebecker M, Priestman DA, Platt FM, Mills K, Biswas A, Cooper JD, Chan JKY, Cheng SH, Waddington SN, Rahim AA.

Nat Med. 2018 Sep;24(9):1317-1323. doi: 10.1038/s41591-018-0106-7. Epub 2018 Jul 16.


Health risk communication message comprehension is influenced by image inclusion.

Manno FAM 3rd, Lively MB, Manno SHC, Cheng SH, Lau C.

J Vis Commun Med. 2018 Oct;41(4):157-165. doi: 10.1080/17453054.2018.1480321. Epub 2018 Jul 10.


Patterns of emergent resistance-associated mutations after initiation of non-nucleoside reverse-transcriptase inhibitor-containing antiretroviral regimens in Taiwan: a multicenter cohort study.

Cheng CY, Tsai MS, Yang CJ, Cheng SH, Sun HY, Chang SF, Su LH, Su YC, Hung CC, Chang SY.

Infect Drug Resist. 2018 Jun 5;11:849-859. doi: 10.2147/IDR.S158341. eCollection 2018.


The impact of a medication record sharing program among diabetes patients under a single-payer system: The role of inquiry rate.

Lin JH, Cheng SH.

Int J Med Inform. 2018 Aug;116:18-23. doi: 10.1016/j.ijmedinf.2018.05.004. Epub 2018 May 19.


[Transmitted drug resistance among HIV infected men who have sex with men in Tianjin, 2014-2017].

Zheng MN, Ning TL, Zhou N, Zhao X, Li L, Zhu JJ, Cheng SH.

Zhonghua Liu Xing Bing Xue Za Zhi. 2018 May 10;39(5):619-624. doi: 10.3760/cma.j.issn.0254-6450.2018.05.015. Chinese.


Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain.

Sullivan JA, Stanek LM, Lukason MJ, Bu J, Osmond SR, Barry EA, O'Riordan CR, Shihabuddin LS, Cheng SH, Scaria A.

Gene Ther. 2018 Jun;25(3):205-219. doi: 10.1038/s41434-018-0017-8. Epub 2018 May 22.


Sequencing-based counting and size profiling of plasma Epstein-Barr virus DNA enhance population screening of nasopharyngeal carcinoma.

Lam WKJ, Jiang P, Chan KCA, Cheng SH, Zhang H, Peng W, Tse OYO, Tong YK, Gai W, Zee BCY, Ma BBY, Hui EP, Chan ATC, Woo JKS, Chiu RWK, Lo YMD.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5115-E5124. doi: 10.1073/pnas.1804184115. Epub 2018 May 14.


Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing.

Sun K, Jiang P, Wong AIC, Cheng YKY, Cheng SH, Zhang H, Chan KCA, Leung TY, Chiu RWK, Lo YMD.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5106-E5114. doi: 10.1073/pnas.1804134115. Epub 2018 May 14.


Survival without adjuvant chemotherapy for selected patients with stage II and III nasopharyngeal carcinoma after concurrent chemoradiotherapy alone.

Wu JS, Tsai YC, Jian JJ, Chen HH, Horng CF, Cheng SH.

Head Neck. 2018 Sep;40(9):2070-2077. doi: 10.1002/hed.25205. Epub 2018 May 13.


Correction to: Soluble delta-like 1 homolog (DLK1) stimulates angiogenesis through Notch1/Akt/eNOS signaling in endothelial cells.

Huang CC, Kuo HM, Wu PC, Cheng SH, Chang TT, Chang YC, Kung ML, Wu DC, Chuang JH, Tai MH.

Angiogenesis. 2018 Nov;21(4):901. doi: 10.1007/s10456-018-9615-8.


Matrix metalloproteinases (MMPs) mediate leukocyte recruitment during the inflammatory phase of zebrafish heart regeneration.

Xu S, Webb SE, Lau TCK, Cheng SH.

Sci Rep. 2018 May 8;8(1):7199. doi: 10.1038/s41598-018-25490-w.


Health Expenditure Growth under Single-Payer Systems: Comparing South Korea and Taiwan.

Cheng SH, Jin HH, Yang BM, Blank RH.

Value Health Reg Issues. 2018 May;15:149-154. doi: 10.1016/j.vhri.2018.03.002. Epub 2018 May 4.


Anti-interferon-γ auto-anti-body and disseminated non-tuberculous mycobacteria infections in thyroid cancer: a case report.

Hung TC, Chen SC, Liao KS, Cheng SH, Chang SL.

QJM. 2018 Sep 1;111(9):647-648. doi: 10.1093/qjmed/hcy094. No abstract available.


[Effects of urethral fibrosis on urinary control after laparoscopic radical prostatectomy].

Liang YC, Wu YP, Cai H, Cheng SH, Wei Y, Xue XY, Zheng QS, Huang JB, Lin YZ, Xu N.

Zhonghua Yi Xue Za Zhi. 2018 Apr 10;98(14):1099-1102. doi: 10.3760/cma.j.issn.0376-2491.2018.14.010. Chinese.


Using machine learning to advance synthesis and use of conservation and environmental evidence.

Cheng SH, Augustin C, Bethel A, Gill D, Anzaroot S, Brun J, DeWilde B, Minnich RC, Garside R, Masuda YJ, Miller DC, Wilkie D, Wongbusarakum S, McKinnon MC.

Conserv Biol. 2018 Aug;32(4):762-764. doi: 10.1111/cobi.13117. No abstract available.


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