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Preeclamptic Women Are at Significantly Higher Risk of Future Cardiovascular Outcomes Over a 15-Year Period.

Gastrich MD, Zinonos S, Bachmann G, Cosgrove' NM, Cabrera J, Cheng JQ, Kostis JB.

J Womens Health (Larchmt). 2019 Aug 16. doi: 10.1089/jwh.2019.7671. [Epub ahead of print]


Analysis of 27 β-Blockers and Metabolites in Milk Powder by High Performance Liquid Chromatography Coupled to Quadrupole Orbitrap High-Resolution Mass Spectrometry.

Cheng JQ, Liu T, Nie XM, Chen FM, Wang CS, Zhang F.

Molecules. 2019 Feb 25;24(4). pii: E820. doi: 10.3390/molecules24040820.


Reevaluation of the post-marketing safety of Xuebijing injection based on real-world and evidence-based evaluations.

Wang C, Shi QP, Ding F, Jiang XD, Tang W, Yu ML, Cheng JQ.

Biomed Pharmacother. 2019 Jan;109:1523-1531. doi: 10.1016/j.biopha.2018.10.190. Epub 2018 Nov 14.


[A study on the burden and causes of hospitalization and deaths in Shenzhen, between 1995 and 2014].

Zhang J, Hong LC, Wang XB, Wei YZ, Hu G, Wu SH, Cheng JQ.

Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Oct 10;39(10):1309-1313. doi: 10.3760/cma.j.issn.0254-6450.2018.10.004. Chinese.


Multipartite entanglement, quantum coherence, and quantum criticality in triangular and Sierpiński fractal lattices.

Cheng JQ, Xu JB.

Phys Rev E. 2018 Jun;97(6-1):062134. doi: 10.1103/PhysRevE.97.062134.


Let-7b regulates alpaca hair growth by downregulating ectodysplasin A.

Liu N, Niu S, Cao XR, Cheng JQ, Gao SY, Yu XJ, Wang HD, Dong CS, He XY.

Mol Med Rep. 2018 Mar;17(3):4688-4694. doi: 10.3892/mmr.2018.8442. Epub 2018 Jan 17.


The effect of primary total knee arthroplasty on the incidence of falls and balance-related functions in patients with osteoarthritis.

Si HB, Zeng Y, Zhong J, Zhou ZK, Lu YR, Cheng JQ, Ning N, Shen B.

Sci Rep. 2017 Nov 29;7(1):16583. doi: 10.1038/s41598-017-16867-4.


Pollen magnetofection for genetic modification with magnetic nanoparticles as gene carriers.

Zhao X, Meng Z, Wang Y, Chen W, Sun C, Cui B, Cui J, Yu M, Zeng Z, Guo S, Luo D, Cheng JQ, Zhang R, Cui H.

Nat Plants. 2017 Dec;3(12):956-964. doi: 10.1038/s41477-017-0063-z. Epub 2017 Nov 27.


[Spectrum and case fatality of inpatients with malignant tumors from 1995 to 2014 in Shenzhen city].

Wang XB, Hong LC, Wei YZ, Fu X, Bao XQ, Zhang J, Hu G, Wu SH, Cheng JQ.

Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Jun 10;38(6):784-788. doi: 10.3760/cma.j.issn.0254-6450.2017.06.019. Chinese.


Intra-articular injection of microRNA-140 (miRNA-140) alleviates osteoarthritis (OA) progression by modulating extracellular matrix (ECM) homeostasis in rats.

Si HB, Zeng Y, Liu SY, Zhou ZK, Chen YN, Cheng JQ, Lu YR, Shen B.

Osteoarthritis Cartilage. 2017 Oct;25(10):1698-1707. doi: 10.1016/j.joca.2017.06.002. Epub 2017 Jun 21.


Correlations between inflammatory cytokines, muscle damage markers and acute postoperative pain following primary total knee arthroplasty.

Si HB, Yang TM, Zeng Y, Zhou ZK, Pei FX, Lu YR, Cheng JQ, Shen B.

BMC Musculoskelet Disord. 2017 Jun 17;18(1):265. doi: 10.1186/s12891-017-1597-y.


Control-released basic fibroblast growth factor-loaded poly-lactic-co-glycolic acid microspheres promote sciatic nerve regeneration in rats.

Si HB, Zeng Y, Lu YR, Cheng JQ, Shen B.

Exp Ther Med. 2017 Feb;13(2):429-436. doi: 10.3892/etm.2016.4013. Epub 2016 Dec 29.


Integration of Population-Level Genotype Data with Functional Annotation Reveals Over-Representation of Long Noncoding RNAs at Ovarian Cancer Susceptibility Loci.

Reid BM, Permuth JB, Chen YA, Teer JK, Monteiro AN, Chen Z, Tyrer J, Berchuck A, Chenevix-Trench G, Doherty JA, Goode EL, Iverson ES, Lawrenson K, Pearce CL, Pharoah PD, Phelan CM, Ramus SJ, Rossing MA, Schildkraut JM, Cheng JQ, Gayther SA, Sellers TA; Ovarian Cancer Association Consortium; Australian Ovarian Cancer Study Group and the Ovarian Cancer Association Consortium; Ovarian Cancer Association Consortium.

Cancer Epidemiol Biomarkers Prev. 2017 Jan;26(1):116-125. doi: 10.1158/1055-9965.EPI-16-0341. Epub 2016 Dec 29.


Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration.

Permuth JB, Reid B, Earp M, Chen YA, Monteiro AN, Chen Z; AOCS Study Group, Chenevix-Trench G, Fasching PA, Beckmann MW, Lambrechts D, Vanderstichele A, Van Niewenhuyse E, Vergote I, Rossing MA, Doherty JA, Chang-Claude J, Moysich K, Odunsi K, Goodman MT, Shvetsov YB, Wilkens LR, Thompson PJ, Dörk T, Bogdanova N, Butzow R, Nevanlinna H, Pelttari L, Leminen A, Modugno F, Edwards RP, Ness RB, Kelley J, Heitz F, Karlan B, Lester J, Kjaer SK, Jensen A, Giles G, Hildebrandt M, Liang D, Lu KH, Wu X, Levine DA, Bisogna M, Berchuck A, Cramer DW, Terry KL, Tworoger SS, Poole EM, Bandera EV, Fridley B, Cunningham J, Winham SJ, Olson SH, Orlow I, Bjorge L, Kiemeney LA, Massuger L, Pejovic T, Moffitt M, Le N, Cook LS, Brooks-Wilson A, Kelemen LE, Gronwald J, Lubinski J, Wentzensen N, Brinton LA, Lissowska J, Yang H, Hogdall E, Hogdall C, Lundvall L, Pharoah PD, Song H, Campbell I, Eccles D, McNeish I, Whittemore A, McGuire V, Sieh W, Rothstein J, Phelan CM, Risch H, Narod S, McLaughlin J, Anton-Culver H, Ziogas A, Menon U, Gayther S, Ramus SJ, Gentry-Maharaj A, Pearce CL, Wu AH, Kupryjanczyk J, Dansonka-Mieszkowska A, Schildkraut JM, Cheng JQ, Goode EL, Sellers TA.

Oncotarget. 2016 Nov 8;7(45):72381-72394. doi: 10.18632/oncotarget.10546.


Ischemic Stroke Rate Increases in Young Adults: Evidence for a Generational Effect?

Swerdel JN, Rhoads GG, Cheng JQ, Cosgrove NM, Moreyra AE, Kostis JB, Kostis WJ; Myocardial Infarction Data Acquisition System (MIDAS 29) Study Group.

J Am Heart Assoc. 2016 Nov 23;5(12). pii: e004245.



Richards EJ, Zhang G, Li ZP, Permuth-Wey J, Challa S, Li Y, Kong W, Dan S, Bui MM, Coppola D, Mao WM, Sellers TA, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22860. No abstract available.


MicroRNA-221/222 negatively regulates estrogen receptor α and is associated with tamoxifen resistance in breast cancer.

Zhao JJ, Lin J, Yang H, Kong W, He L, Ma X, Coppola D, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22859. No abstract available.


Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120.

Yuan Z, Kim D, Shu S, Wu J, Guo J, Xiao L, Kaneko S, Coppola D, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22858. No abstract available.


IKKϵ phosphorylation of estrogen receptor α Ser-167 and contribution to tamoxifen resistance in breast cancer.

Guo JP, Shu SK, Esposito NN, Coppola D, Koomen JM, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22857. No abstract available.


A small molecule inhibits Akt through direct binding to Akt and preventing Akt membrane translocation.

Kim D, Sun M, He L, Zhou QH, Chen J, Sun XM, Bepler G, Sebti SM, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22856. No abstract available.


MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer.

Kong W, He L, Coppola M, Guo J, Esposito NN, Coppola D, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22855. No abstract available.


Phosphorylation and activation of androgen receptor by Aurora-A.

Shu SK, Liu Q, Coppola D, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22854. No abstract available.


Identification of Akt interaction protein PHF20/TZP that transcriptionally regulates p53.

Park S, Kim D, Dan HC, Chen H, Testa JR, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22852. No abstract available.


MicroRNA MiR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog.

Xu CX, Xu M, Tan L, Yang H, Permuth-Wey J, Kruk PA, Wenham RM, Nicosia SV, Lancaster JM, Sellers TA, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22851. No abstract available.


Positive feedback regulation between Akt2 and MyoD during muscle differentiation. CLONING OF Akt2 PROMOTER.

Kaneko S, Feldman RI, Yu L, Wu Z, Gritsko T, Shelley SA, Nicosia SV, Nobori T, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22850. No abstract available.


Inhibition of JNK by cellular stress- and tumor necrosis factor α-induced AKT2 through activation of the NFκB pathway in human epithelial cells.

Yuan ZQ, Feldman RI, Sun M, Olashaw NE, Coppola D, Sussman GE, Shelley SA, Nicosia SV, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22849. No abstract available.


Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin.

Dan HC, Sun M, Yang L, Feldman RI, Sui XM, Ou CC, Nellist M, Yeung RS, Halley DJ, Nicosia SV, Pledger WJ, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22848. No abstract available.


AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1. IMPLICATION OF AKT2 IN CHEMORESISTANCE.

Yuan ZQ, Feldman RI, Sussman GE, Coppola D, Nicosia SV, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22847. No abstract available.


Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

Dan HC, Sun M, Kaneko S, Feldman RI, Nicosia SV, Wang HG, Tsang BK, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22846. No abstract available.


ArgBP2γ interacts with Akt and p21-activated kinase-1 and promotes cell survival.

Yuan ZQ, Kim D, Kaneko S, Sussman M, Bokoch GM, Kruh GD, Nicosia SV, Testa JR, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22845. No abstract available.


Molecular cloning and characterization of the human AKT1 promoter uncovers its up-regulation by the Src/Stat3 pathway.

Park S, Kim D, Kaneko S, Szewczyk KM, Nicosia SV, Yu H, Jove R, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22844. No abstract available.


Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212.

Yang L, Sun M, Sun XM, Cheng GZ, Nicosia SV, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22843. No abstract available.


Identification of Aurora-A as a direct target of E2F3 during G2/M cell cycle progression.

He L, Yang H, Ma Y, Pledger WJ, Cress WD, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22842. No abstract available.


Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85α, androgen receptor, and Src.

Sun M, Yang L, Feldman RI, Sun XM, Bhalla KN, Jove R, Nicosia SV, Cheng JQ.

J Biol Chem. 2016 Oct 21;291(43):22841. No abstract available.


Exendin-4 Ameliorates Lipotoxicity-induced Glomerular Endothelial Cell Injury by Improving ABC Transporter A1-mediated Cholesterol Efflux in Diabetic apoE Knockout Mice.

Yin QH, Zhang R, Li L, Wang YT, Liu JP, Zhang J, Bai L, Cheng JQ, Fu P, Liu F.

J Biol Chem. 2016 Dec 16;291(51):26487-26501. Epub 2016 Oct 26.


[Impact of PM2.5 on daily outpatient numbers for respiratory diseases in Shenzhen, China].

Peng CQ, Cai JF, Yu SY, Cao ZJ, Liao YX, Liu N, He L, Zhang L, Zheng J, Shi XM, Cheng JQ.

Zhonghua Yu Fang Yi Xue Za Zhi. 2016 Oct 6;50(10):874-879. doi: 10.3760/cma.j.issn.0253-9624.2016.10.008. Chinese.


Identification and Whole-Genome Sequencing of Four Enterovirus D68 Strains in Southern China in Late 2015.

Chen L, Shi L, Yang H, Gu DY, Meng J, Xu YQ, Yao XJ, Zhang HL, Cheng JQ, Ma HW, Zhang RL, He YQ.

Genome Announc. 2016 Sep 22;4(5). pii: e01014-16. doi: 10.1128/genomeA.01014-16.


pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.

Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang J, Zhang L, Yuan M, Novak J, Cheng JQ, Toker A, Signoretti S, Zhang Q, Asara JM, Kaelin WG Jr, Wei W.

Science. 2016 Aug 26;353(6302):929-32. doi: 10.1126/science.aad5755.


IKBKE Is a Substrate of EGFR and a Therapeutic Target in Non-Small Cell Lung Cancer with Activating Mutations of EGFR.

Challa S, Guo JP, Ding X, Xu CX, Li Y, Kim D, Smith MA, Cress DW, Coppola D, Haura EB, Cheng JQ.

Cancer Res. 2016 Aug 1;76(15):4418-29. doi: 10.1158/0008-5472.CAN-16-0069. Epub 2016 Jun 10.


Resveratrol Ameliorates the Anxiety- and Depression-Like Behavior of Subclinical Hypothyroidism Rat: Possible Involvement of the HPT Axis, HPA Axis, and Wnt/β-Catenin Pathway.

Ge JF, Xu YY, Qin G, Cheng JQ, Chen FH.

Front Endocrinol (Lausanne). 2016 May 24;7:44. doi: 10.3389/fendo.2016.00044. eCollection 2016.


Oxazole: A Promising Building Block for the Development of Potent Antitumor Agents.

Zhou H, Cheng JQ, Wang ZS, Chen FH, Liu XH.

Curr Top Med Chem. 2016;16(30):3582-3589.


Effects of functional genetic variants in PPARδ encoding peroxisome proliferator-activated receptor delta on the risk of ischemic stroke in Chinese Han population.

Tong Y, Huang X, Wang Z, Han S, Guan X, Lin L, Li X, Hou S, Wang L, Cai B, Liu J, Cheng JQ, Lu Z.

Int J Cardiol. 2016 Mar 15;207:297-9. doi: 10.1016/j.ijcard.2016.01.171. Epub 2016 Jan 11. No abstract available.


Adenomatous polyposis coli (APC) regulates miR17-92 cluster through β-catenin pathway in colorectal cancer.

Li Y, Lauriola M, Kim D, Francesconi M, D'Uva G, Shibata D, Malafa MP, Yeatman TJ, Coppola D, Solmi R, Cheng JQ.

Oncogene. 2016 Sep 1;35(35):4558-4568. doi: 10.1038/onc.2015.522. Epub 2016 Jan 25.


Functional Genetic Variants of PPARx03B3; and PPARα Encoding Peroxisome Proliferator-Activated Receptors and Susceptibility to Ischemic Stroke in Chinese Han Population.

Tong Y, Cai L, Han S, Lu Q, Guan X, Ying X, Hou S, Zhan F, Cheng JQ, Liu J.

Cerebrovasc Dis. 2016;41(1-2):96-9. doi: 10.1159/000442306. Epub 2015 Dec 16.


Nesfatin-1, a potent anorexic agent, decreases exploration and induces anxiety-like behavior in rats without altering learning or memory.

Ge JF, Xu YY, Qin G, Pan XY, Cheng JQ, Chen FH.

Brain Res. 2015 Dec 10;1629:171-81. doi: 10.1016/j.brainres.2015.10.027. Epub 2015 Oct 21.


A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer.

Richards EJ, Permuth-Wey J, Li Y, Chen YA, Coppola D, Reid BM, Lin HY, Teer JK, Berchuck A, Birrer MJ, Lawrenson K, Monteiro AN, Schildkraut JM, Goode EL, Gayther SA, Sellers TA, Cheng JQ.

Oncotarget. 2015 Oct 27;6(33):34745-57. doi: 10.18632/oncotarget.5784.


Usefulness of a normal coronary angiogram in patients aged ≥65 years to foretell survival.

Moreyra AE, Charalambous M, Cosgrove NM, Rajaei S, Cullen K, Cheng JQ, David A, Kostis WJ, Kostis JB; MIDAS Study Group (MIDAS 26).

Am J Cardiol. 2015 Nov 15;116(10):1487-94. doi: 10.1016/j.amjcard.2015.08.009. Epub 2015 Aug 31.


A preliminary validation of the Brief COPE instrument for assessing coping strategies among people living with HIV in China.

Su XY, Lau JT, Mak WW, Choi KC, Feng TJ, Chen X, Liu CL, Liu J, Liu D, Chen L, Song JM, Zhang Y, Zhao GL, Zhu ZP, Cheng JQ.

Infect Dis Poverty. 2015 Sep 14;4:41. doi: 10.1186/s40249-015-0074-9.


STAT3 polymorphisms may predict an unfavorable response to first-line platinum-based therapy for women with advanced serous epithelial ovarian cancer.

Permuth-Wey J, Fulp WJ, Reid BM, Chen Z, Georgeades C, Cheng JQ, Magliocco A, Chen DT, Lancaster JM.

Int J Cancer. 2016 Feb 1;138(3):612-9. doi: 10.1002/ijc.29799. Epub 2015 Aug 28.

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