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Items: 1 to 50 of 145


Molecular Profiling of Cohorts of Tumor Samples to Guide Clinical Development of Pembrolizumab as Monotherapy.

Ayers M, Nebozhyn M, Cristescu R, McClanahan TK, Perini R, Rubin E, Cheng JD, Kaufman DR, Loboda A.

Clin Cancer Res. 2018 Nov 15. doi: 10.1158/1078-0432.CCR-18-1316. [Epub ahead of print]


[An investigation and analysis of abnormal menstruation in female nurses in a hospital in Beijing, China].

Wang ZH, Sun ZF, Ye Y, Hu L, Yu GX, Sun LG, Yu WL, Cheng JD, Sun X, Shen Z.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2018 Jun 20;36(6):429-432. doi: 10.3760/cma.j.issn.1001-9391.2018.06.008. Chinese.


Clinical outcomes with therapies for previously treated recurrent/metastatic head-and-neck squamous cell carcinoma (R/M HNSCC): A systematic literature review.

Lala M, Chirovsky D, Cheng JD, Mayawala K.

Oral Oncol. 2018 Sep;84:108-120. doi: 10.1016/j.oraloncology.2018.07.005. Epub 2018 Aug 1. Review.


[A meta-analysis of Symptom Checklist-90 assessment results in Chinese nurses].

Wang ZH, Ye Y, Shen Z, Sun LG, Hu L, Yu WL, Xu M, Sun ZF, Cheng JD, Sun X.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2018 Feb 20;36(2):129-133. doi: 10.3760/cma.j.issn.1001-9391.2018.02.013. Chinese.


[Research Progress on Determination of Drowning Site].

Zhao J, Xu LW, Kang XD, Shi H, Liu C, Hu SL, Yang XY, Xu QY, Cheng JD, Ai M.

Fa Yi Xue Za Zhi. 2018 Feb;34(1):55-59. doi: 10.3969/j.issn.1004-5619.2018.01.011. Epub 2018 Feb 25. Review. Chinese.


Teaching forensic pathology to undergraduates at Zhongshan School of Medicine.

Zhou N, Wu QP, Su T, Zhao QH, Yin K, Zheng D, Zheng JJ, Huang L, Cheng JD.

Med Sci Law. 2018 Apr;58(2):109-114. doi: 10.1177/0025802418760044. Epub 2018 Feb 21.


Pembrolizumab in Asia-Pacific patients with advanced head and neck squamous cell carcinoma: Analyses from KEYNOTE-012.

Tahara M, Muro K, Hasegawa Y, Chung HC, Lin CC, Keam B, Takahashi K, Cheng JD, Bang YJ.

Cancer Sci. 2018 Mar;109(3):771-776. doi: 10.1111/cas.13480. Epub 2018 Feb 8.


[Research Progress of Sudden Cardiac Death in Forensic Medicine].

Zheng D, Yin K, Zheng JJ, Zhou N, Liu Y, Fu X, Cheng JD.

Fa Yi Xue Za Zhi. 2017 Oct;33(5):457-469. doi: 10.3969/j.issn.1004-5619.2017.05.002. Epub 2017 Oct 25. Review. Chinese.


[Research Progress of the Relationship between SUNDS and OSAHS].

Wu YD, Zhang LY, Cheng JD.

Fa Yi Xue Za Zhi. 2017 Feb;33(1):52-57. doi: 10.3969/j.issn.1004-5619.2017.01.013. Epub 2017 Feb 25. Review. Chinese.


Safety and Antitumor Activity of Pembrolizumab in Patients With Programmed Death-Ligand 1-Positive Nasopharyngeal Carcinoma: Results of the KEYNOTE-028 Study.

Hsu C, Lee SH, Ejadi S, Even C, Cohen RB, Le Tourneau C, Mehnert JM, Algazi A, van Brummelen EMJ, Saraf S, Thanigaimani P, Cheng JD, Hansen AR.

J Clin Oncol. 2017 Dec 20;35(36):4050-4056. doi: 10.1200/JCO.2017.73.3675. Epub 2017 Aug 24.


IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade.

Ayers M, Lunceford J, Nebozhyn M, Murphy E, Loboda A, Kaufman DR, Albright A, Cheng JD, Kang SP, Shankaran V, Piha-Paul SA, Yearley J, Seiwert TY, Ribas A, McClanahan TK.

J Clin Invest. 2017 Aug 1;127(8):2930-2940. doi: 10.1172/JCI91190. Epub 2017 Jun 26.


Xyloketal B alleviates cerebral infarction and neurologic deficits in a mouse stroke model by suppressing the ROS/TLR4/NF-κB inflammatory signaling pathway.

Pan N, Lu LY, Li M, Wang GH, Sun FY, Sun HS, Wen XJ, Cheng JD, Chen JW, Pang JY, Liu J, Guan YY, Zhao LY, Chen WL, Wang GL.

Acta Pharmacol Sin. 2017 Sep;38(9):1236-1247. doi: 10.1038/aps.2017.22. Epub 2017 May 29.


LNK deficiency aggravates palmitate-induced preadipocyte apoptosis.

Du JY, Jin CC, Wang GH, Huang XQ, Cheng JD, Wen XJ, Zhao XM, Wang GL.

Biochem Biophys Res Commun. 2017 Aug 19;490(2):91-97. doi: 10.1016/j.bbrc.2017.05.057. Epub 2017 May 17.


Asymmetric Total Syntheses of (-)-α-Lycorane, (-)-Zephyranthine, and Formal Synthesis of (+)-Clivonine.

Chen YJ, Cai SL, Wang CC, Cheng JD, Kramer S, Sun XW.

Chem Asian J. 2017 Jun 19;12(12):1309-1313. doi: 10.1002/asia.201700555. Epub 2017 May 31.


Pembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study.

Bauml J, Seiwert TY, Pfister DG, Worden F, Liu SV, Gilbert J, Saba NF, Weiss J, Wirth L, Sukari A, Kang H, Gibson MK, Massarelli E, Powell S, Meister A, Shu X, Cheng JD, Haddad R.

J Clin Oncol. 2017 May 10;35(14):1542-1549. doi: 10.1200/JCO.2016.70.1524. Epub 2017 Mar 22.


A novel mutation in the STK11 gene causes heritable Peutz-Jeghers syndrome - a case report.

Chen JH, Zheng JJ, Guo Q, Liu C, Luo B, Tang SB, Cheng JD, Huang EW.

BMC Med Genet. 2017 Feb 23;18(1):19. doi: 10.1186/s12881-017-0373-z.


CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts.

Tang CM, Zhang M, Huang L, Hu ZQ, Zhu JN, Xiao Z, Zhang Z, Lin QX, Zheng XL, -Yang M, Wu SL, Cheng JD, Shan ZX.

Sci Rep. 2017 Jan 12;7:40342. doi: 10.1038/srep40342.


Myocyte-specific enhancer factor 2C: a novel target gene of miR-214-3p in suppressing angiotensin II-induced cardiomyocyte hypertrophy.

Tang CM, Liu FZ, Zhu JN, Fu YH, Lin QX, Deng CY, Hu ZQ, Yang H, Zheng XL, Cheng JD, Wu SL, Shan ZX.

Sci Rep. 2016 Oct 31;6:36146. doi: 10.1038/srep36146.


Intrapancreatic distal common bile duct carcinoma: Analysis, staging considerations, and comparison with pancreatic ductal and ampullary adenocarcinomas.

Gonzalez RS, Bagci P, Basturk O, Reid MD, Balci S, Knight JH, Kong SY, Memis B, Jang KT, Ohike N, Tajiri T, Bandyopadhyay S, Krasinskas AM, Kim GE, Cheng JD, Adsay NV.

Mod Pathol. 2016 Nov;29(11):1358-1369. doi: 10.1038/modpathol.2016.125. Epub 2016 Jul 29.


Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort.

Chow LQM, Haddad R, Gupta S, Mahipal A, Mehra R, Tahara M, Berger R, Eder JP, Burtness B, Lee SH, Keam B, Kang H, Muro K, Weiss J, Geva R, Lin CC, Chung HC, Meister A, Dolled-Filhart M, Pathiraja K, Cheng JD, Seiwert TY.

J Clin Oncol. 2016 Nov 10;34(32):3838-3845. doi: 10.1200/JCO.2016.68.1478. Epub 2016 Sep 30.


Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial.

Seiwert TY, Burtness B, Mehra R, Weiss J, Berger R, Eder JP, Heath K, McClanahan T, Lunceford J, Gause C, Cheng JD, Chow LQ.

Lancet Oncol. 2016 Jul;17(7):956-965. doi: 10.1016/S1470-2045(16)30066-3. Epub 2016 May 27.


Pembrolizumab in Patients With Advanced Triple-Negative Breast Cancer: Phase Ib KEYNOTE-012 Study.

Nanda R, Chow LQ, Dees EC, Berger R, Gupta S, Geva R, Pusztai L, Pathiraja K, Aktan G, Cheng JD, Karantza V, Buisseret L.

J Clin Oncol. 2016 Jul 20;34(21):2460-7. doi: 10.1200/JCO.2015.64.8931. Epub 2016 May 2.


Induction Therapy for Locally Advanced, Resectable Esophagogastric Cancer: A Phase I Trial of Vandetanib (ZD6474), Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiotherapy Followed by Resection.

Boland PM, Meyer JE, Berger AC, Cohen SJ, Neuman T, Cooper HS, Olszanski AJ, Davey M, Cheng JD, Lebenthal A, Burtness BA, Scott WJ, Astsaturov IA.

Am J Clin Oncol. 2017 Aug;40(4):393-398. doi: 10.1097/COC.0000000000000171.


Investigation of associations between ten polymorphisms and the risk of coronary artery disease in Southern Han Chinese.

Huang EW, Peng LY, Zheng JX, Wang D, Tan XH, Yang ZY, Li XM, Wu QP, Tang SB, Luo B, Quan L, Liu SP, Liu XS, Li ZH, Shi H, Lv GL, Zhao J, Liu C, Cheng JD.

J Hum Genet. 2016 May;61(5):389-93. doi: 10.1038/jhg.2015.158. Epub 2016 Jan 7.


Common Variants in Promoter of ADTRP Associate with Early-Onset Coronary Artery Disease in a Southern Han Chinese Population.

Huang EW, Peng LY, Zheng JX, Wang D, Xu QY, Huang L, Wu QP, Tang SB, Luo B, Liu SP, Liu XS, Li ZH, Quan L, Li Y, Shi H, Lv GL, Zhao J, Cheng JD, Liu C.

PLoS One. 2015 Sep 16;10(9):e0137547. doi: 10.1371/journal.pone.0137547. eCollection 2015.


[Simulation and Observation of Vertical Cast-off Bloodstain Pattern].

Zhao L, Lu MF, He W, Cheng HY, Cheng JD.

Fa Yi Xue Za Zhi. 2015 Apr;31(2):102-4. Chinese.


Results of a phase 1 trial combining ridaforolimus and MK-0752 in patients with advanced solid tumours.

Piha-Paul SA, Munster PN, Hollebecque A, Argilés G, Dajani O, Cheng JD, Wang R, Swift A, Tosolini A, Gupta S.

Eur J Cancer. 2015 Sep;51(14):1865-73. doi: 10.1016/j.ejca.2015.06.115. Epub 2015 Jul 18.


A Phase I Trial of Combined Ridaforolimus and MK-2206 in Patients with Advanced Malignancies.

Gupta S, Argilés G, Munster PN, Hollebecque A, Dajani O, Cheng JD, Wang R, Swift A, Tosolini A, Piha-Paul SA.

Clin Cancer Res. 2015 Dec 1;21(23):5235-44. doi: 10.1158/1078-0432.CCR-15-0180. Epub 2015 Jul 17.


G6PD Deficiency and Hemoglobinopathies: Molecular Epidemiological Characteristics and Healthy Effects on Malaria Endemic Bioko Island, Equatorial Guinea.

Lin M, Yang LY, Xie DD, Chen JT, Nguba SM, Ehapo CS, Zhan XF, Eyi JU, Matesa RA, Obono MM, Yang H, Yang HT, Cheng JD.

PLoS One. 2015 Apr 27;10(4):e0123991. doi: 10.1371/journal.pone.0123991. eCollection 2015.


Underestimated Prevalence of Chronic Heart Failure among the Elderly Residing in Care Homes in Aruba.

Stoutjesdijk E, Barents M, Brouns RM, DeJongste MJ, Besselink HJ, Cheng JD, Wever R, Muskiet FA.

West Indian Med J. 2014 Jul 3;63(6):610-5. doi: 10.7727/wimj.2013.277. Epub 2014 Nov 4.


[Death caused by anaphylactic shock: a forensic pathological analysis of 142 cases].

Hu DY, Huang C, Liu SG, Huang L, Zheng JX, Huang EW, Wu QP, Cheng JD, Tang SB.

Fa Yi Xue Za Zhi. 2014 Aug;30(4):267-9. Chinese.


Identification of a neurologic scale that optimizes EMS detection of older adult traumatic brain injury patients who require transport to a trauma center.

Wasserman EB, Shah MN, Jones CM, Cushman JT, Caterino JM, Bazarian JJ, Gillespie SM, Cheng JD, Dozier A.

Prehosp Emerg Care. 2015 Apr-Jun;19(2):202-12. doi: 10.3109/10903127.2014.959225. Epub 2014 Oct 7.


A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours.

Brana I, Berger R, Golan T, Haluska P, Edenfield J, Fiorica J, Stephenson J, Martin LP, Westin S, Hanjani P, Jones MB, Almhanna K, Wenham RM, Sullivan DM, Dalton WS, Gunchenko A, Cheng JD, Siu LL, Gray JE.

Br J Cancer. 2014 Nov 11;111(10):1932-44. doi: 10.1038/bjc.2014.497. Epub 2014 Oct 7.


[Epidemiological characters of Yunnan sudden death syndrome and its research progress].

Zheng JX, Zhao S, Huang WL, Huang L, Tang SB, Ben C, Cheng JD.

Fa Yi Xue Za Zhi. 2014 Apr;30(2):122-5. Review. Chinese.


[Diatoms in drowned and postmortem immersed rabbits' lungs].

Li XY, Zhao J, Liu C, Hu SL, Zhang YC, Wen JF, Cheng JD.

Fa Yi Xue Za Zhi. 2014 Apr;30(2):81-4, 87. Chinese.


Inhibition of ovarian cancer cell proliferation by Pien Tze Huang via the AKT-mTOR pathway.

He F, Wu HN, Cai MY, Li CP, Zhang X, Wan Q, Tang SB, Cheng JD.

Oncol Lett. 2014 Jun;7(6):2047-2052. Epub 2014 Mar 21.


Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold.

Jansen K, Heirbaut L, Cheng JD, Joossens J, Ryabtsova O, Cos P, Maes L, Lambeir AM, De Meester I, Augustyns K, Van der Veken P.

ACS Med Chem Lett. 2013 Mar 18;4(5):491-6. doi: 10.1021/ml300410d. eCollection 2013 May 9.


The up-regulation of endothelin-1 and down-regulation of miRNA-125a-5p, -155, and -199a/b-3p in human atherosclerotic coronary artery.

Hao L, Wang XG, Cheng JD, You SZ, Ma SH, Zhong X, Quan L, Luo B.

Cardiovasc Pathol. 2014 Jul-Aug;23(4):217-23. doi: 10.1016/j.carpath.2014.03.009. Epub 2014 Apr 5.


EEN regulates the proliferation and survival of multiple myeloma cells by potentiating IGF-1 secretion.

Huang EW, Xue SJ, Li XY, Xu SW, Cheng JD, Zheng JX, Shi H, Lv GL, Li ZG, Li Y, Liu CH, Chen XH, Liu H, Li J, Liu C.

Biochem Biophys Res Commun. 2014 May 2;447(2):271-7. doi: 10.1016/j.bbrc.2014.03.127. Epub 2014 Apr 2.


Women at increased risk for cardiac toxicity following chemoradiation therapy for esophageal carcinoma.

Tait LM, Meyer JE, McSpadden E, Cheng JD, Baciewicz FA, Meropol NJ, Cohen SJ, Wozniak AJ, Choi M, Konski AA.

Pract Radiat Oncol. 2013 Oct-Dec;3(4):e149-55. doi: 10.1016/j.prro.2013.02.001. Epub 2013 Mar 13.


Extended structure-activity relationship and pharmacokinetic investigation of (4-quinolinoyl)glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP).

Jansen K, Heirbaut L, Verkerk R, Cheng JD, Joossens J, Cos P, Maes L, Lambeir AM, De Meester I, Augustyns K, Van der Veken P.

J Med Chem. 2014 Apr 10;57(7):3053-74. doi: 10.1021/jm500031w. Epub 2014 Mar 24.


A phase II trial of the proteasome inhibitor bortezomib in patients with advanced biliary tract cancers.

Denlinger CS, Meropol NJ, Li T, Lewis NL, Engstrom PF, Weiner LM, Cheng JD, Alpaugh RK, Cooper H, Wright JJ, Cohen SJ.

Clin Colorectal Cancer. 2014 Jun;13(2):81-6. doi: 10.1016/j.clcc.2013.12.005. Epub 2014 Jan 4.


[Gene detection of GPD1-L and the association with sudden unexplained death syndrome in young adults].

Xu XL, Wang W, Liu C, Hou YD, Huang L, Liu CH, Li Y, Cheng JD.

Fa Yi Xue Za Zhi. 2013 Oct;29(5):348-52. Chinese.


Whipple made simple for surgical pathologists: orientation, dissection, and sampling of pancreaticoduodenectomy specimens for a more practical and accurate evaluation of pancreatic, distal common bile duct, and ampullary tumors.

Adsay NV, Basturk O, Saka B, Bagci P, Ozdemir D, Balci S, Sarmiento JM, Kooby DA, Staley C, Maithel SK, Everett R, Cheng JD, Thirabanjasak D, Weaver DW.

Am J Surg Pathol. 2014 Apr;38(4):480-93. doi: 10.1097/PAS.0000000000000165.


Assessment of surgical residents' ability to predict appendicitis with computed tomography.

Kahn SA, Sleem R, Schiralli M, Stassen NA, Sangosanya A, Cheng JD, Gestring ML, Bankey PE.

Am Surg. 2013 Dec;79(12):1308-10. No abstract available.


[Sudden death caused by aortic dissection: 63 cases of forensic pathological analysis].

Huang L, Liu SG, Huang C, Yu DY, Zheng L, Cheng JD, Tang SB.

Fa Yi Xue Za Zhi. 2013 Aug;29(4):273-5. Chinese.


Recombination analysis of autosomal short tandem repeats in Chinese Han families.

Liu QL, Luo H, Zhao H, Huang XL, Cheng JD, Lu DJ.

Electrophoresis. 2014 Mar;35(6):883-7. doi: 10.1002/elps.201300417. Epub 2013 Dec 9.


[Study on the pollutants removal performance along the advanced treatment in tannery wastewater by O3-BAF].

Yu B, Liu R, Cheng JD, Fan JH, Li CH, Ran K, Cao GH, Chen LJ.

Huan Jing Ke Xue. 2013 Mar;34(3):974-8. Chinese.


Risk factors associated with venous thromboembolism in isolated blunt chest trauma.

Kahn SA, Schubmehl H, Stassen NA, Sangosanya A, Cheng JD, Gestring ML, Bankey PE.

Am Surg. 2013 May;79(5):502-5.


Selective nonoperative management of blunt splenic injury: an Eastern Association for the Surgery of Trauma practice management guideline.

Stassen NA, Bhullar I, Cheng JD, Crandall ML, Friese RS, Guillamondegui OD, Jawa RS, Maung AA, Rohs TJ Jr, Sangosanya A, Schuster KM, Seamon MJ, Tchorz KM, Zarzuar BL, Kerwin AJ; Eastern Association for the Surgery of Trauma.

J Trauma Acute Care Surg. 2012 Nov;73(5 Suppl 4):S294-300. doi: 10.1097/TA.0b013e3182702afc.


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