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Incorporating Simplified Fournier's Gangrene Severity Index with early surgical intervention can maximize survival in high-risk Fournier's gangrene patients.

Lin TY, Cheng IH, Ou CH, Tsai YS, Tong YC, Cheng HL, Yang WH, Lin YM, Cheng YS.

Int J Urol. 2019 Apr 18. doi: 10.1111/iju.13989. [Epub ahead of print]


The Asylum Seeker Integrated Healthcare Pathway: a collaborative approach to improving access to primary health care in South Eastern Melbourne, Victoria, Australia.

Cheng IH, McBride J, Decker M, Watson T, Jakubenko H, Russo A.

Aust J Prim Health. 2019 Mar;25(1):6-12. doi: 10.1071/PY18028.


Ginkgolide A Prevents the Amyloid-β-Induced Depolarization of Cortical Neurons.

Kuo LC, Song YQ, Yao CA, Cheng IH, Chien CT, Lee GC, Yang WC, Lin Y.

J Agric Food Chem. 2019 Jan 9;67(1):81-89. doi: 10.1021/acs.jafc.8b04514. Epub 2018 Dec 21.


Intracellular trafficking of TREM2 is regulated by presenilin 1.

Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H.

Exp Mol Med. 2017 Dec 1;49(12):e405. doi: 10.1038/emm.2017.200.


Curcuminoid submicron particle ameliorates cognitive deficits and decreases amyloid pathology in Alzheimer's disease mouse model.

Tai YH, Lin YY, Wang KC, Chang CL, Chen RY, Wu CC, Cheng IH.

Oncotarget. 2018 Jan 31;9(12):10681-10697. doi: 10.18632/oncotarget.24369. eCollection 2018 Feb 13.


Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.

Liu YL, Chen WT, Lin YY, Lu PH, Hsieh SL, Cheng IH.

Mol Neurodegener. 2017 Apr 24;12(1):30. doi: 10.1186/s13024-017-0173-0.


A systematic review of studies with a representative sample of refugees and asylum seekers living in the community for participation in mental health research.

Enticott JC, Shawyer F, Vasi S, Buck K, Cheng IH, Russell G, Kakuma R, Minas H, Meadows G.

BMC Med Res Methodol. 2017 Mar 2;17(1):37. doi: 10.1186/s12874-017-0312-x. Review.


The mental health status of refugees and asylum seekers attending a refugee health clinic including comparisons with a matched sample of Australian-born residents.

Shawyer F, Enticott JC, Block AA, Cheng IH, Meadows GN.

BMC Psychiatry. 2017 Feb 21;17(1):76. doi: 10.1186/s12888-017-1239-9.


Acceptability of general practice services for Afghan refugees in south-eastern Melbourne.

Manchikanti P, Cheng IH, Advocat J, Russell G.

Aust J Prim Health. 2017 Apr;23(1):87-91. doi: 10.1071/PY16020.


Behavioral alterations following blood-brain barrier disruption stimulated by focused ultrasound.

Yang FY, Huang SF, Cheng IH.

Oncotarget. 2016 May 10;7(19):27916-25. doi: 10.18632/oncotarget.8444.


Alterations of the Neuroinflammatory Markers IL-6 and TRAIL in Alzheimer's Disease.

Wu YY, Hsu JL, Wang HC, Wu SJ, Hong CJ, Cheng IH.

Dement Geriatr Cogn Dis Extra. 2015 Nov 24;5(3):424-34. doi: 10.1159/000439214. eCollection 2015 Sep-Dec.


Rites of passage: improving refugee access to general practice services.

Cheng IH, Vasi S, Wahidi S, Russell G.

Aust Fam Physician. 2015 Jul;44(7):503-7.


Bridging the Gap: using an interrupted time series design to evaluate systems reform addressing refugee maternal and child health inequalities.

Yelland J, Riggs E, Szwarc J, Casey S, Dawson W, Vanpraag D, East C, Wallace E, Teale G, Harrison B, Petschel P, Furler J, Goldfeld S, Mensah F, Biro MA, Willey S, Cheng IH, Small R, Brown S.

Implement Sci. 2015 Apr 30;10:62. doi: 10.1186/s13012-015-0251-z.


Maternal health and pregnancy outcomes comparing migrant women born in humanitarian and nonhumanitarian source countries: a retrospective, observational study.

Gibson-Helm ME, Teede HJ, Cheng IH, Block AA, Knight M, East CE, Wallace EM, Boyle JA.

Birth. 2015 Jun;42(2):116-24. doi: 10.1111/birt.12159. Epub 2015 Apr 11.


Refugee experiences of general practice in countries of resettlement: a literature review.

Cheng IH, Drillich A, Schattner P.

Br J Gen Pract. 2015 Mar;65(632):e171-6. doi: 10.3399/bjgp15X683977. Review.


Maternal health and pregnancy outcomes among women of refugee background from Asian countries.

Gibson-Helm M, Boyle J, Cheng IH, East C, Knight M, Teede H.

Int J Gynaecol Obstet. 2015 May;129(2):146-51. doi: 10.1016/j.ijgo.2014.10.036. Epub 2015 Jan 17.


Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus.

Cheng KW, Cheng SC, Chen WY, Lin MH, Chuang SJ, Cheng IH, Sun CY, Chou CY.

Antiviral Res. 2015 Mar;115:9-16. doi: 10.1016/j.antiviral.2014.12.011. Epub 2014 Dec 24.


A cross-sectional survey of the mental health needs of refugees and asylum seekers attending a refugee health clinic: a study protocol for using research to inform local service delivery.

Shawyer F, Enticott JC, Doherty AR, Block AA, Cheng IH, Wahidi S, Meadows GN.

BMC Psychiatry. 2014 Dec 24;14:356. doi: 10.1186/s12888-014-0356-y.


G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.

Chen WT, Hsieh YF, Huang YJ, Lin CC, Lin YT, Liu YC, Lien CC, Cheng IH.

Mol Neurobiol. 2015 Dec;52(3):1835-1849. doi: 10.1007/s12035-014-8969-1. Epub 2014 Nov 15.


Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients.

Fang YS, Tsai KJ, Chang YJ, Kao P, Woods R, Kuo PH, Wu CC, Liao JY, Chou SC, Lin V, Jin LW, Yuan HS, Cheng IH, Tu PH, Chen YR.

Nat Commun. 2014 Sep 12;5:4824. doi: 10.1038/ncomms5824.


Importance of community engagement in primary health care: the case of Afghan refugees.

Cheng IH, Wahidi S, Vasi S, Samuel S.

Aust J Prim Health. 2015;21(3):262-7.


Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production.

Lin YC, Wang JY, Wang KC, Liao JY, Cheng IH.

J Neurochem. 2014 Nov;131(4):407-12. doi: 10.1111/jnc.12829. Epub 2014 Aug 13.


On the crucial cerebellar wound healing-related pathways and their cross-talks after traumatic brain injury in Danio rerio.

Wu CC, Tsai TH, Chang C, Lee TT, Lin C, Cheng IH, Sun MC, Chuang YJ, Chen BS.

PLoS One. 2014 Jun 13;9(6):e97902. doi: 10.1371/journal.pone.0097902. eCollection 2014.


A narrative synthesis of the impact of primary health care delivery models for refugees in resettlement countries on access, quality and coordination.

Joshi C, Russell G, Cheng IH, Kay M, Pottie K, Alston M, Smith M, Chan B, Vasi S, Lo W, Wahidi SS, Harris MF.

Int J Equity Health. 2013 Nov 7;12:88. doi: 10.1186/1475-9276-12-88. Review.


Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memory.

Wu PY, Huang YY, Chen CC, Hsu TT, Lin YC, Weng JY, Chien TC, Cheng IH, Lien CC.

J Neurosci. 2013 Jan 30;33(5):1828-32. doi: 10.1523/JNEUROSCI.4132-12.2013.


Potential blood biomarker for disease severity in the Taiwanese population with Alzheimer's disease.

Huang CW, Wang SJ, Wu SJ, Yang CC, Huang MW, Lin CH, Cheng IH.

Am J Alzheimers Dis Other Demen. 2013 Feb;28(1):75-83. doi: 10.1177/1533317512467674. Epub 2012 Dec 10.


Crude caffeine reduces memory impairment and amyloid β(1-42) levels in an Alzheimer's mouse model.

Chu YF, Chang WH, Black RM, Liu JR, Sompol P, Chen Y, Wei H, Zhao Q, Cheng IH.

Food Chem. 2012 Dec 1;135(3):2095-102. doi: 10.1016/j.foodchem.2012.04.148. Epub 2012 Jun 29.


Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies.

Chen WT, Hong CJ, Lin YT, Chang WH, Huang HT, Liao JY, Chang YJ, Hsieh YF, Cheng CY, Liu HC, Chen YR, Cheng IH.

PLoS One. 2012;7(4):e35807. doi: 10.1371/journal.pone.0035807. Epub 2012 Apr 30.


The NSW Refugee Health Service - improving refugee access to primary care.

Milosevic D, Cheng IH, Smith MM.

Aust Fam Physician. 2012 Mar;41(3):147-9.


Collagen VI protects against neuronal apoptosis elicited by ultraviolet irradiation via an Akt/phosphatidylinositol 3-kinase signaling pathway.

Cheng IH, Lin YC, Hwang E, Huang HT, Chang WH, Liu YL, Chao CY.

Neuroscience. 2011 Jun 2;183:178-88. doi: 10.1016/j.neuroscience.2011.03.057. Epub 2011 Apr 1.


Clinical phenotype of G206D mutation in the presenilin 1 gene in pathologically confirmed familial Alzheimer's disease.

Wu YY, Cheng IH, Lee CC, Chiu MJ, Lee MJ, Chen TF, Hsu JL.

J Alzheimers Dis. 2011;25(1):145-50. doi: 10.3233/JAD-2011-102031.


Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation.

Chen WT, Liao YH, Yu HM, Cheng IH, Chen YR.

J Biol Chem. 2011 Mar 18;286(11):9646-56. doi: 10.1074/jbc.M110.177246. Epub 2011 Jan 7.


ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin.

Hong CJ, Tsai PJ, Cheng CY, Chou CK, Jheng HF, Chuang YC, Yang CN, Lin YT, Hsu CW, Cheng IH, Chen SY, Tsai SJ, Liou YJ, Tsai YS.

PLoS One. 2010 Dec 9;5(12):e15333. doi: 10.1371/journal.pone.0015333.


Assessing the TARES as an ethical model for antismoking ads.

Lee ST, Cheng IH.

J Health Commun. 2010 Jan;15(1):55-75. doi: 10.1080/10810730903460542.


Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees.

Chu YF, Brown PH, Lyle BJ, Chen Y, Black RM, Williams CE, Lin YC, Hsu CW, Cheng IH.

J Agric Food Chem. 2009 Oct 28;57(20):9801-8. doi: 10.1021/jf902095z.


The effects of frame, appeal, and outcome extremity of antismoking messages on cognitive processing.

Leshner G, Cheng IH.

Health Commun. 2009 Apr;24(3):219-27. doi: 10.1080/10410230902804117.


Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.

Meilandt WJ, Cisse M, Ho K, Wu T, Esposito LA, Scearce-Levie K, Cheng IH, Yu GQ, Mucke L.

J Neurosci. 2009 Feb 18;29(7):1977-86. doi: 10.1523/JNEUROSCI.2984-08.2009.


Collagen VI protects neurons against Abeta toxicity.

Cheng JS, Dubal DB, Kim DH, Legleiter J, Cheng IH, Yu GQ, Tesseur I, Wyss-Coray T, Bonaldo P, Mucke L.

Nat Neurosci. 2009 Feb;12(2):119-21. doi: 10.1038/nn.2240. Epub 2009 Jan 4.


Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.

Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L.

Nat Neurosci. 2008 Nov;11(11):1311-8. doi: 10.1038/nn.2213. Epub 2008 Oct 19.


Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.

Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L.

J Biol Chem. 2007 Aug 17;282(33):23818-28. Epub 2007 Jun 4.


Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model.

Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L.

Science. 2007 May 4;316(5825):750-4.


Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration.

Ji ZS, Müllendorff K, Cheng IH, Miranda RD, Huang Y, Mahley RW.

J Biol Chem. 2006 Feb 3;281(5):2683-92. Epub 2005 Nov 17.


Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation.

Cheng IH, Palop JJ, Esposito LA, Bien-Ly N, Yan F, Mucke L.

Nat Med. 2004 Nov;10(11):1190-2. Epub 2004 Oct 24.


Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae.

Sawyer SL, Cheng IH, Chai W, Tye BK.

J Mol Biol. 2004 Jul 2;340(2):195-202.


Investigation of resistance of bacteria from commercial poultry sources to commercial disinfectants.

Sander JE, Hofacre CL, Cheng IH, Wyatt RD.

Avian Dis. 2002 Oct-Dec;46(4):997-1000.


Mcm3 is polyubiquitinated during mitosis before establishment of the pre-replication complex.

Cheng IH, Roberts LA, Tye BK.

J Biol Chem. 2002 Nov 1;277(44):41706-14. Epub 2002 Aug 27.


Two mcm3 mutations affect different steps in the initiation of DNA replication.

Lei M, Cheng IH, Roberts LA, McAlear MA, Tye BK.

J Biol Chem. 2002 Aug 23;277(34):30824-31. Epub 2002 Jun 11.

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