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Associations of plasma trimethylamine N-oxide, choline, carnitine, and betaine with inflammatory and cardiometabolic risk biomarkers and the fecal microbiome in the Multiethnic Cohort Adiposity Phenotype Study.

Fu BC, Hullar MAJ, Randolph TW, Franke AA, Monroe KR, Cheng I, Wilkens LR, Shepherd JA, Madeleine MM, Le Marchand L, Lim U, Lampe JW.

Am J Clin Nutr. 2020 Feb 13. pii: nqaa015. doi: 10.1093/ajcn/nqaa015. [Epub ahead of print]


Adult Spinal Deformity Surgery in Patients With Movement Disorders: A Propensity-matched Analysis of Outcomes and Cost.

Varshneya K, Azad TD, Pendharkar AV, Desai A, Cheng I, Karikari I, Ratliff JK, Veeravagu A.

Spine (Phila Pa 1976). 2020 Mar 1;45(5):E288-E295. doi: 10.1097/BRS.0000000000003251.


Computer-assisted surgical navigation is associated with an increased risk of neurological complications: a review of 67,264 posterolateral lumbar fusion cases.

Ajiboye RM, Koltsov JCB, Karamian B, Swinford S, Montgomery BK, Arzeno A, Ziino C, Cheng I.

J Spine Surg. 2019 Dec;5(4):457-465. doi: 10.21037/jss.2019.09.21.


Molecular dissection of TNFR-TNFα bidirectional signaling reveals both cooperative and antagonistic interactions with p75 neurotrophic factor receptor in axon patterning.

Kuhn KD, Edamura K, Bhatia N, Cheng I, Clark SA, Haynes CV, Heffner DL, Kabir F, Velasquez J, Spano AJ, Deppmann CD, Keeler AB.

Mol Cell Neurosci. 2020 Jan 28:103467. doi: 10.1016/j.mcn.2020.103467. [Epub ahead of print]


Oral administration of porcine epidemic diarrhea virus spike protein expressing in silkworm pupae failed to elicit immune responses in pigs.

Chang CY, Hsu WT, Tsai PS, Chen CM, Cheng IC, Chao YC, Chang HW.

AMB Express. 2020 Jan 28;10(1):20. doi: 10.1186/s13568-020-0952-9.


Changes in Plasma Amyloid and Tau in a Longitudinal Study of Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease.

Chen TB, Lai YH, Ke TL, Chen JP, Lee YJ, Lin SY, Lin PC, Wang PN, Cheng IH.

Dement Geriatr Cogn Disord. 2020 Jan 28:1-16. doi: 10.1159/000505435. [Epub ahead of print]


Short-Term Outcomes of Staged Versus Same-Day Surgery for Adult Spinal Deformity Correction.

Arzeno AH, Koltsov J, Alamin TF, Cheng I, Wood KB, Hu SS.

Spine Deform. 2019 Sep;7(5):796-804. doi: 10.1016/j.jspd.2018.12.008. Epub 2019 Dec 30.


Twenty-three Years of Sea Turtle Stranding/ bycatch Research in Taiwan.

Cheng IJ, Wang HY, Hsieh WY, Chan YT.

Zool Stud. 2019 Dec 19;58:e44. doi: 10.6620/ZS.2019.58-44. eCollection 2019.


Using Programming Languages and Geographic Information System to Determine Spatial and Temporal Variability in a Green Turtle Foraging Population on Liuchiu Island, Taiwan.

Cheng WH, Chan YT, Hong H, Johnson B, Cheng IJ.

Zool Stud. 2019 Aug 1;58:e18. doi: 10.6620/ZS.2019.58-18. eCollection 2019.


Automatic Classification and Monitoring of Denovo Parkinson's Disease by Learning Demographic and Clinical Features.

Soltaninejad S, Basu A, Cheng I.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:3968-3971. doi: 10.1109/EMBC.2019.8857729.


Comparison of bone structure and microstructure in the metacarpal heads between patients with psoriatic arthritis and healthy controls: an HR-pQCT study.

Wu D, Griffith JF, Lam SHM, Wong P, Yue J, Shi L, Li EK, Cheng IT, Li TK, Hung VW, Qin L, Tam LS.

Osteoporos Int. 2020 Jan 14. doi: 10.1007/s00198-020-05298-z. [Epub ahead of print]


Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility.

Kachuri L, Johansson M, Rashkin SR, Graff RE, Bossé Y, Manem V, Caporaso NE, Landi MT, Christiani DC, Vineis P, Liu G, Scelo G, Zaridze D, Shete SS, Albanes D, Aldrich MC, Tardón A, Rennert G, Chen C, Goodman GE, Doherty JA, Bickeböller H, Field JK, Davies MP, Dawn Teare M, Kiemeney LA, Bojesen SE, Haugen A, Zienolddiny S, Lam S, Le Marchand L, Cheng I, Schabath MB, Duell EJ, Andrew AS, Manjer J, Lazarus P, Arnold S, McKay JD, Emami NC, Warkentin MT, Brhane Y, Obeidat M, Martin RM, Relton C, Davey Smith G, Haycock PC, Amos CI, Brennan P, Witte JS, Hung RJ.

Nat Commun. 2020 Jan 7;11(1):27. doi: 10.1038/s41467-019-13855-2.


Association of change in the neighborhood obesogenic environment with colorectal cancer risk: The Multiethnic Cohort Study.

Shvetsov YB, Shariff-Marco S, Yang J, Conroy SM, Canchola AJ, Albright CL, Park SY, Monroe KR, Le Marchand L, Gomez SL, Wilkens LR, Cheng I.

SSM Popul Health. 2019 Dec 24;10:100532. doi: 10.1016/j.ssmph.2019.100532. eCollection 2020 Apr.


Particulate Matter Increases the Severity of Bleomycin-Induced Pulmonary Fibrosis through KC-Mediated Neutrophil Chemotaxis.

Cheng IY, Liu CC, Lin JH, Hsu TW, Hsu JW, Li AF, Ho WC, Hung SC, Hsu HS.

Int J Mol Sci. 2019 Dec 28;21(1). pii: E227. doi: 10.3390/ijms21010227.


Timing of Lumbar Spinal Fusion Affects Total Hip Arthroplasty Outcomes.

Bala A, Chona DV, Amanatullah DF, Hu SS, Wood KB, Alamin TF, Cheng I.

J Am Acad Orthop Surg Glob Res Rev. 2019 Nov 4;3(11):e00133. doi: 10.5435/JAAOSGlobal-D-19-00133. eCollection 2019 Nov.


Assessing the therapeutic potential of Graptopetalum paraguayense on Alzheimer's disease using patient iPSC-derived neurons.

Wu PC, Fann MJ, Tran TT, Chen SC, Devina T, Cheng IH, Lien CC, Kao LS, Wang SJ, Fuh JL, Tzeng TT, Huang CY, Shiao YJ, Wong YH.

Sci Rep. 2019 Dec 17;9(1):19301. doi: 10.1038/s41598-019-55614-9.


Critical Factors in Human Antizymes that Determine the Differential Binding, Inhibition, and Degradation of Human Ornithine Decarboxylase.

Hsieh JY, Liu YC, Cheng IT, Lee CJ, Wang YH, Fang YS, Liu YL, Liu GY, Hung HC.

Biomolecules. 2019 Dec 12;9(12). pii: E864. doi: 10.3390/biom9120864.


Progressive structural bone changes and their relationship with treatment in patients with psoriatic arthritis: a longitudinal HR-pQCT study.

Wu D, Griffith JF, Lam SHM, Wong PCH, Shi L, Li EK, Cheng IT, Li TK, Hung VW, Qin L, Tam LS.

Arthritis Res Ther. 2019 Dec 4;21(1):265. doi: 10.1186/s13075-019-2043-3.


The use of ceftolozane-tazobactam in the treatment of complicated intra-abdominal infections and complicated urinary tract infections-A meta-analysis of randomized controlled trials.

Cheng IL, Chen YH, Lai CC, Tang HJ.

Int J Antimicrob Agents. 2020 Feb;55(2):105858. doi: 10.1016/j.ijantimicag.2019.11.015. Epub 2019 Nov 28.


An updated review of atmospheric mercury.

Lyman SN, Cheng I, Gratz LE, Weiss-Penzias P, Zhang L.

Sci Total Environ. 2020 Mar 10;707:135575. doi: 10.1016/j.scitotenv.2019.135575. Epub 2019 Nov 20.


Left ventricular diastolic dysfunction in HIV-uninfected infants exposed in utero to antiretroviral therapy.

Lipshultz SE, Sasaki N, Thompson B, Eidem BW, Cheng I, Colan SD, O'brien SE, Amdani SM, Shearer WT, Orav EJ, Miller TL, Wilkinson JD.

AIDS. 2019 Nov 14. doi: 10.1097/QAD.0000000000002443. [Epub ahead of print]


Making Contributions and Defining Success: An eDelphi Study of the Inaugural Cohort of CIHR Health System Impact Fellows, Host Supervisors and Academic Supervisors.

Blanchette MA, Saari M, Aubrecht K, Bailey C, Cheng I, Embrett M, Ghandour EK, Haw J, Koval A, Liu RH, Manhas KP, Mawani FN, Mcconnell-Nzunga J, Petricca K, Sim M, Singal D, Syrowatka A, Lai J.

Healthc Policy. 2019 Oct;15(SP):49-60. doi: 10.12927/hcpol.2019.25980.


Geographical and temporal origins of Neocaridina species (Decapoda: Caridea: Atyidae) in Taiwan.

Han CC, Hsu KC, Fang LS, Cheng IM, Lin HD.

BMC Genet. 2019 Nov 21;20(1):86. doi: 10.1186/s12863-019-0788-y.


Utilizing a Single Silica Nanospring as an Insulating Support to Characterize the Electrical Transport and Morphology of Nanocrystalline Graphite.

Wojcik PM, Rajabi N, Zhu H, Estrada D, Davis PH, Pandhi T, Cheng IF, McIlroy DN.

Materials (Basel). 2019 Nov 19;12(22). pii: E3794. doi: 10.3390/ma12223794.


Persistence of HIV reservoir following successful haematopoietic stem cell transplant for juvenile myelomonocytic leukaemia in a child with perinatally acquired HIV.

Dobson G, Klein N, Veys P, Qasim W, Silva J, Cheng IL, Shingadia D, Tudor-Williams G, Watters SA, Lyall H, Rao A, Foster C, Bamford A.

J Virus Erad. 2019 Sep 18;5(3):174-177.


Persistence of HIV reservoir following successful haematopoietic stem cell transplant for juvenile myelomonocytic leukaemia in a child with perinatally acquired HIV.

Dobson G, Klein N, Veys P, Qasim W, Silva J, Cheng IL, Shingadia D, Tudor-Williams G, Watters SA, Lyall H, Rao A, Foster C, Bamford A.

J Virus Erad. 2019 Sep 18;5(3):174-177.


Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle.

Wu J, Saovieng S, Cheng IS, Liu T, Hong S, Lin CY, Su IC, Huang CY, Kuo CH.

J Ginseng Res. 2019 Oct;43(4):580-588. doi: 10.1016/j.jgr.2018.06.002. Epub 2018 Jun 21.


Does ACDF Utilization and Reimbursement Change Based on Certificate of Need Status?

Ziino C, Bala A, Cheng I.

Clin Spine Surg. 2019 Nov 5. doi: 10.1097/BSD.0000000000000914. [Epub ahead of print]


p75NTR and DR6 Regulate Distinct Phases of Axon Degeneration Demarcated by Spheroid Rupture.

Yong Y, Gamage K, Cheng I, Barford K, Spano A, Winckler B, Deppmann C.

J Neurosci. 2019 Nov 27;39(48):9503-9520. doi: 10.1523/JNEUROSCI.1867-19.2019. Epub 2019 Oct 18.


Association between mitochondrial genetic variation and breast cancer risk: The Multiethnic Cohort.

Li Y, Giorgi EE, Beckman KB, Caberto C, Kazma R, Lum-Jones A, Haiman CA, Marchand LL, Stram DO, Saxena R, Cheng I.

PLoS One. 2019 Oct 2;14(10):e0222284. doi: 10.1371/journal.pone.0222284. eCollection 2019.


Patient Preferences for Shared Decision Making: Not All Decisions Should Be Shared.

E Lindsay S, Alokozai A, Eppler SL, Fox P, Curtin C, Gardner M, Avedian R, Palanca A, Abrams GD, Cheng I, Kamal RN; VOICES Health Policy Research Investigators:.

J Am Acad Orthop Surg. 2019 Sep 25. doi: 10.5435/JAAOS-D-19-00146. [Epub ahead of print]


Plasma Aβ42 and Total Tau Predict Cognitive Decline in Amnestic Mild Cognitive Impairment.

Chen TB, Lee YJ, Lin SY, Chen JP, Hu CJ, Wang PN, Cheng IH.

Sci Rep. 2019 Sep 27;9(1):13984. doi: 10.1038/s41598-019-50315-9.


Single-Level In Vitro Kinematic Comparison of Novel Inline Cervical Interbody Devices With Intervertebral Screw, Anchor, or Blade.

Arnold PM, Cheng I, Harris JA, Hussain MM, Zhang C, Karamian B, Bucklen BS.

Global Spine J. 2019 Oct;9(7):697-707. doi: 10.1177/2192568219833055. Epub 2019 Feb 28.


Short-Term Outcomes of Staged Versus Same-Day Surgery for Adult Spinal Deformity Correction.

Arzeno AH, Koltsov J, Alamin TF, Cheng I, Wood KB, Hu SS.

Spine Deform. 2019 Sep;7(5):796-803.e1. doi: 10.1016/j.jspd.2018.12.008.


Seaweed Supplementation Enhances Maximal Muscular Strength and Attenuates Resistance Exercise-Induced Oxidative Stress in Rats.

Korivi M, Chen CT, Yu SH, Ye W, Cheng IS, Chang JS, Kuo CH, Hou CW.

Evid Based Complement Alternat Med. 2019 Jul 28;2019:3528932. doi: 10.1155/2019/3528932. eCollection 2019.


Electrochemical determination of free chlorine on pseudo-graphite electrode.

Kabir H, Ma PY, Renn N, Nicholas NW, Cheng IF.

Talanta. 2019 Dec 1;205:120101. doi: 10.1016/j.talanta.2019.06.101. Epub 2019 Jul 2.


Grade II Spondylolisthesis: Reverse Bohlman Procedure with Transdiscal S1-L5 and S2 Alar Iliac Screws Placed with Robotic Guidance.

Ho AL, Varshneya K, Medress ZA, Pendharkar AV, Sussman ES, Cheng I, Veeravagu A.

World Neurosurg. 2019 Dec;132:421-428.e1. doi: 10.1016/j.wneu.2019.07.229. Epub 2019 Aug 6.


Decreased estimated blood loss in lateral trans-psoas versus anterior approach to lumbar interbody fusion for degenerative spondylolisthesis.

Goodnough LH, Koltsov J, Wang T, Xiong G, Nathan K, Cheng I.

J Spine Surg. 2019 Jun;5(2):185-193. doi: 10.21037/jss.2019.05.08.


The effects of varenicline on lumbar spinal fusion in a rat model.

R Kang J, Glaeser JD, Karamian B, Kanim L, NaPier Z, Koltsov J, Thio T, Salehi K, Bae HW, Cheng I.

Spine J. 2020 Feb;20(2):300-306. doi: 10.1016/j.spinee.2019.07.015. Epub 2019 Aug 1.


Acute kidney injury in an infant with severe combined immunodeficiency: Answers.

Malakasioti G, Alders N, Lucchini G, Cheng IL, Bockenhauer D.

Pediatr Nephrol. 2019 Dec;34(12):2541-2544. doi: 10.1007/s00467-019-04303-w. Epub 2019 Jul 16. No abstract available.


Acute kidney injury in an infant with severe combined immunodeficiency: Questions.

Malakasioti G, Alders N, Lucchini G, Cheng IL, Bockenhauer D.

Pediatr Nephrol. 2019 Dec;34(12):2539-2540. doi: 10.1007/s00467-019-04302-x. Epub 2019 Jul 16. No abstract available.


Retrospective case series describing the efficacy, safety and cost-effectiveness of a vial-sharing programme for canakinumab treatment for paediatric patients with cryopyrin-associated periodic syndrome.

Elmi AA, Wynne K, Cheng IL, Eleftheriou D, Lachmann HJ, Hawkins PN, Brogan P.

Pediatr Rheumatol Online J. 2019 Jul 8;17(1):36. doi: 10.1186/s12969-019-0335-4.


The Efficacy and Safety of Doripenem in the Treatment of Acute Bacterial Infections-A Systemic Review and Meta-Analysis of Randomized Controlled Trials.

Lai CC, Cheng IL, Chen YH, Tang HJ.

J Clin Med. 2019 Jul 2;8(7). pii: E958. doi: 10.3390/jcm8070958. Review.


CIHR Health System Impact Fellows: Reflections on "Driving Change" Within the Health System.

Sim SM, Lai J, Aubrecht K, Cheng I, Embrett M, Ghandour EK, Highet M, Liu R, Casteli CP, Saari M, Ouédraogo S, Williams-Roberts H.

Int J Health Policy Manag. 2019 Jun 1;8(6):325-328. doi: 10.15171/ijhpm.2018.124.


Genetic analyses of diverse populations improves discovery for complex traits.

Wojcik GL, Graff M, Nishimura KK, Tao R, Haessler J, Gignoux CR, Highland HM, Patel YM, Sorokin EP, Avery CL, Belbin GM, Bien SA, Cheng I, Cullina S, Hodonsky CJ, Hu Y, Huckins LM, Jeff J, Justice AE, Kocarnik JM, Lim U, Lin BM, Lu Y, Nelson SC, Park SL, Poisner H, Preuss MH, Richard MA, Schurmann C, Setiawan VW, Sockell A, Vahi K, Verbanck M, Vishnu A, Walker RW, Young KL, Zubair N, Acuña-Alonso V, Ambite JL, Barnes KC, Boerwinkle E, Bottinger EP, Bustamante CD, Caberto C, Canizales-Quinteros S, Conomos MP, Deelman E, Do R, Doheny K, Fernández-Rhodes L, Fornage M, Hailu B, Heiss G, Henn BM, Hindorff LA, Jackson RD, Laurie CA, Laurie CC, Li Y, Lin DY, Moreno-Estrada A, Nadkarni G, Norman PJ, Pooler LC, Reiner AP, Romm J, Sabatti C, Sandoval K, Sheng X, Stahl EA, Stram DO, Thornton TA, Wassel CL, Wilkens LR, Winkler CA, Yoneyama S, Buyske S, Haiman CA, Kooperberg C, Le Marchand L, Loos RJF, Matise TC, North KE, Peters U, Kenny EE, Carlson CS.

Nature. 2019 Jun;570(7762):514-518. doi: 10.1038/s41586-019-1310-4. Epub 2019 Jun 19.


The OPTIMISE project: protocol for a mixed methods, pragmatic, quasi-experimental trial to improve primary care delivery to refugees in Australia.

Russell G, Gunatillaka N, Lewis V, Cheng IH, Enticott J, Marsh G, Vasi S, Advocat J, Song H, Saito S, Casey S, Smith M, Harris M.

BMC Health Serv Res. 2019 Jun 19;19(1):396. doi: 10.1186/s12913-019-4235-6.


Comparison of high-dose, short-course levofloxacin treatment vs conventional regimen against acute bacterial infection: meta-analysis of randomized controlled trials.

Chen CW, Chen YH, Cheng IL, Lai CC.

Infect Drug Resist. 2019 May 17;12:1353-1361. doi: 10.2147/IDR.S193483. eCollection 2019.


Contingent valuation of dolphin watching activities in South China: The difference between local and non-local participants.

Cheung LTO, Ma ATH, Chow ASY, Lee JCK, Fok L, Cheng INY, Cheang FCC.

Sci Total Environ. 2019 Sep 20;684:340-350. doi: 10.1016/j.scitotenv.2019.05.276. Epub 2019 May 23.



Francone A, Yun L, Kothari N, Cheng I, Farajzadeh M, Govetto A, Hubschman JP.

Retina. 2019 May 27. doi: 10.1097/IAE.0000000000002532. [Epub ahead of print]


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