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Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models.

Chen ZS, Li L, Peng S, Chen FM, Zhang Q, An Y, Lin X, Li W, Koon AC, Chan TF, Lau KF, Ngo JCK, Wong WT, Kwan KM, Chan HYE.

EMBO Rep. 2018 Jul 19. pii: e45409. doi: 10.15252/embr.201745409. [Epub ahead of print]


Gold(III)-Catalyzed Regioselective Oxidation/Cycloisomerization of Diynes: An Approach to Fused Furan Derivatives.

Li J, Xing HW, Yang F, Chen ZS, Ji K.

Org Lett. 2018 Aug 3;20(15):4622-4626. doi: 10.1021/acs.orglett.8b01915. Epub 2018 Jul 13.


Oncosis-inducing cyclometalated iridium(iii) complexes.

Guan R, Chen Y, Zeng L, Rees TW, Jin C, Huang J, Chen ZS, Ji L, Chao H.

Chem Sci. 2018 May 3;9(23):5183-5190. doi: 10.1039/c8sc01142g. eCollection 2018 Jun 21.


Discovery of 5-Cyano-6-phenylpyrimidin Derivatives Containing an Acylurea Moiety as Orally Bioavailable Reversal Agents against P-Glycoprotein-Mediated Mutidrug Resistance.

Wang B, Ma LY, Wang JQ, Lei ZN, Gupta P, Zhao YD, Li ZH, Liu Y, Zhang XH, Li YN, Zhao B, Chen ZS, Liu HM.

J Med Chem. 2018 Jul 18. doi: 10.1021/acs.jmedchem.8b00335. [Epub ahead of print]


[Clinical features and prognosis of children with mature B-cell non-Hodgkin's lymphoma: an analysis of 28 cases].

Chen ZS, Zheng YZ, Chen YQ, Gao QL, Li J, Shen JZ.

Zhongguo Dang Dai Er Ke Za Zhi. 2018 Jun;20(6):470-474. Chinese.


Genomic analysis of a novel isolate Heliothis virescens ascovirus 3i (HvAV-3i) and identification of ascoviral repeat ORFs (aros).

Chen ZS, Hou DH, Cheng XW, Wang X, Huang GH.

Arch Virol. 2018 Jun 14. doi: 10.1007/s00705-018-3899-2. [Epub ahead of print]


Curcumin ameliorates cisplatin-induced cystopathy via activating NRF2 pathway.

Shao YP, Zhou Q, Li YP, Zhang SC, Xu HW, Wu S, Shen BX, Ding LC, Xue J, Chen ZS, Wei ZQ.

Neurourol Urodyn. 2018 Jun 19. doi: 10.1002/nau.23731. [Epub ahead of print]


Circulating tumor cells undergoing EMT provide a metric for diagnosis and prognosis of patients with hepatocellular carcinoma.

Qi LN, Xiang BD, Wu FX, Ye JZ, Zhong JH, Wang YY, Chen YY, Chen ZS, Ma L, Chen J, Gong WF, Han ZG, Lu Y, Shang JJ, Li LQ.

Cancer Res. 2018 Jun 18. pii: canres.2459.2017. doi: 10.1158/0008-5472.CAN-17-2459. [Epub ahead of print]


Special Issue: Natural Products: Anticancer and Beyond.

Cui Q, Yang DH, Chen ZS.

Molecules. 2018 May 23;23(6). pii: E1246. doi: 10.3390/molecules23061246. No abstract available.


Evaluation of the Curative Effect of Umbilical Cord Mesenchymal Stem Cell Therapy for Knee Arthritis in Dogs Using Imaging Technology.

Zhang BY, Wang BY, Li SC, Luo DZ, Zhan X, Chen SF, Chen ZS, Liu CY, Ji HQ, Bai YS, Li DS, He Y.

Stem Cells Int. 2018 May 15;2018:1983025. doi: 10.1155/2018/1983025. eCollection 2018.


[Saw palmetto fruit extract improves LUTS in type ⅢA prostatitis patients].

Shao YP, Xue HL, Shen BX, Ding LC, Chen ZS, Wei ZQ.

Zhonghua Nan Ke Xue. 2017 May;23(5):417-421. Chinese.


Epidermal growth factor receptor (EGFR) inhibitor PD153035 reverses ABCG2-mediated multidrug resistance in non-small cell lung cancer: In vitro and in vivo.

Zhang GN, Zhang YK, Wang YJ, Gupta P, Ashby CR Jr, Alqahtani S, Deng T, Bates SE, Kaddoumi A, Wurpel JND, Lei YX, Chen ZS.

Cancer Lett. 2018 Jun 28;424:19-29. doi: 10.1016/j.canlet.2018.02.040. Epub 2018 Mar 5.


TC > 0.05 as a Pharmacokinetic Parameter of Paclitaxel for Therapeutic Efficacy and Toxicity in Cancer Patients.

Xin DS, Zhou L, Li CZ, Zhang SQ, Huang HQ, Qiu GD, Lin LF, She YQ, Zheng JT, Chen C, Fang L, Chen ZS, Zhang SY.

Recent Pat Anticancer Drug Discov. 2018;13(3):341-347. doi: 10.2174/1574892813666180305170439.


Author Correction: Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma.

Wang LL, Chen ZS, Zhou WD, Shu J, Wang XH, Jin R, Zhuang LL, Hoda MA, Zhang H, Zhou GP.

Sci Rep. 2018 Mar 6;8(1):4299. doi: 10.1038/s41598-018-22517-0.


Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors.

Wang Q, Arnst KE, Xue Y, Lei ZN, Ma D, Chen ZS, Miller DD, Li W.

Eur J Med Chem. 2018 Apr 10;149:211-224. doi: 10.1016/j.ejmech.2018.02.045. Epub 2018 Feb 19.


Voruciclib, a Potent CDK4/6 Inhibitor, Antagonizes ABCB1 and ABCG2-Mediated Multi-Drug Resistance in Cancer Cells.

Gupta P, Zhang YK, Zhang XY, Wang YJ, Lu KW, Hall T, Peng R, Yang DH, Xie N, Chen ZS.

Cell Physiol Biochem. 2018;45(4):1515-1528. doi: 10.1159/000487578. Epub 2018 Feb 19.


Elimination of Bimodal Size in InAs/GaAs Quantum Dots for Preparation of 1.3-μm Quantum Dot Lasers.

Su XB, Ding Y, Ma B, Zhang KL, Chen ZS, Li JL, Cui XR, Xu YQ, Ni HQ, Niu ZC.

Nanoscale Res Lett. 2018 Feb 21;13(1):59. doi: 10.1186/s11671-018-2472-y.


Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters.

Fan YF, Zhang W, Zeng L, Lei ZN, Cai CY, Gupta P, Yang DH, Cui Q, Qin ZD, Chen ZS, Trombetta LD.

Cancer Lett. 2018 May 1;421:186-198. doi: 10.1016/j.canlet.2018.01.021. Epub 2018 Jan 11.


A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases.

Zhang Q, Chen ZS, An Y, Liu H, Hou Y, Li W, Lau KF, Koon AC, Ngo JCK, Chan HYE.

RNA. 2018 Apr;24(4):486-498. doi: 10.1261/rna.062703.117. Epub 2018 Jan 2.


Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein.

Patel BA, Abel B, Barbuti AM, Velagapudi UK, Chen ZS, Ambudkar SV, Talele TT.

J Med Chem. 2018 Feb 8;61(3):834-864. doi: 10.1021/acs.jmedchem.7b01340. Epub 2018 Jan 23.


Quizartinib (AC220) reverses ABCG2-mediated multidrug resistance: In vitro and in vivo studies.

Li J, Kumar P, Anreddy N, Zhang YK, Wang YJ, Chen Y, Talele TT, Gupta K, Trombetta LD, Chen ZS.

Oncotarget. 2017 Sep 16;8(55):93785-93799. doi: 10.18632/oncotarget.21078. eCollection 2017 Nov 7.


Cytotoxic and acute toxicity studies of isoniazid derivatives.

Naeem S, Akhtar S, Lei ZN, Lu K, Zafar S, Ahmed A, Ali M, Ahmed M, Chen ZS.

Pak J Pharm Sci. 2017 Nov;30(6(Supplementary)):2411-2415.


Transcription Factor OsTGA10 Is a Target of the MADS Protein OsMADS8 and Is Required for Tapetum Development.

Chen ZS, Liu XF, Wang DH, Chen R, Zhang XL, Xu ZH, Bai SN.

Plant Physiol. 2018 Jan;176(1):819-835. doi: 10.1104/pp.17.01419. Epub 2017 Nov 20.


CDX2 Stimulates the Proliferation of Porcine Intestinal Epithelial Cells by Activating the mTORC1 and Wnt/β-Catenin Signaling Pathways.

Fan HB, Zhai ZY, Li XG, Gao CQ, Yan HC, Chen ZS, Wang XQ.

Int J Mol Sci. 2017 Nov 18;18(11). pii: E2447. doi: 10.3390/ijms18112447.


Exploration of 1,2,3-triazole-pyrimidine hybrids as potent reversal agents against ABCB1-mediated multidrug resistance.

Wang B, Zhao B, Chen ZS, Pang LP, Zhao YD, Guo Q, Zhang XH, Liu Y, Liu GY, Hao-Zhang, Zhang XY, Ma LY, Liu HM.

Eur J Med Chem. 2018 Jan 1;143:1535-1542. doi: 10.1016/j.ejmech.2017.10.041. Epub 2017 Oct 21.


Design, synthesis and biological evaluation of WZ4002 analogues as EGFR inhibitors.

Romu AA, Lei Z, Zhou B, Chen ZS, Korlipara V.

Bioorg Med Chem Lett. 2017 Nov 1;27(21):4832-4837. doi: 10.1016/j.bmcl.2017.09.048. Epub 2017 Sep 25.


Establishment and characterization of arsenic trioxide resistant KB/ATO cells.

Zhang YK, Dai C, Yuan CG, Wu HC, Xiao Z, Lei ZN, Yang DH, Le XC, Fu L, Chen ZS.

Acta Pharm Sin B. 2017 Sep;7(5):564-570. doi: 10.1016/j.apsb.2017.04.001. Epub 2017 Apr 28.


Design, synthesis and biological evaluation of benzamide and phenyltetrazole derivatives with amide and urea linkers as BCRP inhibitors.

Gujarati NA, Zeng L, Gupta P, Chen ZS, Korlipara VL.

Bioorg Med Chem Lett. 2017 Oct 15;27(20):4698-4704. doi: 10.1016/j.bmcl.2017.09.009. Epub 2017 Sep 7.


6,7-Seco-ent-Kauranoids Derived from Oridonin as Potential Anticancer Agents.

Xu S, Yao H, Hu M, Li D, Zhu Z, Xie W, Yao H, Wu L, Chen ZS, Xu J.

J Nat Prod. 2017 Sep 22;80(9):2391-2398. doi: 10.1021/acs.jnatprod.7b00057. Epub 2017 Sep 13.


Simultaneous endoscopic submucosal dissection for multiple early gastric cancers in a low volume center.

Chen ZS, Jin XF, Wu HL, Guo JQ.

Medicine (Baltimore). 2017 Sep;96(36):e7745. doi: 10.1097/MD.0000000000007745.


Selection of reference genes for expression analysis using RT-qPCR in the dissemination system of Heliothis virescens ascovirus 3 h (HvAV-3h).

Chen ZS, Han NN, Li JH, Huang GH, Wan H.

Sci Rep. 2017 Aug 1;7(1):7045. doi: 10.1038/s41598-017-07684-w.


The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

Zeng L, Gupta P, Chen Y, Wang E, Ji L, Chao H, Chen ZS.

Chem Soc Rev. 2017 Oct 2;46(19):5771-5804. doi: 10.1039/c7cs00195a. Review.


Autophagy and multidrug resistance in cancer.

Li YJ, Lei YH, Yao N, Wang CR, Hu N, Ye WC, Zhang DM, Chen ZS.

Chin J Cancer. 2017 Jun 24;36(1):52. doi: 10.1186/s40880-017-0219-2. Review.


Gold-Catalyzed Oxidation Terminal Alkyne: An Approach to Synthesize Substituted Dihydronaphthalen-2(1H)-ones and Phenanthrenols.

Ling HB, Chen ZS, Yang F, Xu B, Gao JM, Ji K.

J Org Chem. 2017 Jul 7;82(13):7070-7076. doi: 10.1021/acs.joc.7b01244. Epub 2017 Jun 22.


Corrigendum to "Anticancer Effects of Salvia miltiorrhiza Alcohol Extract on Oral Squamous Carcinoma Cells".

Wang WH, Kuo YH, Chu LY, Lee CY, Tyan YC, Chen ZS, Tsai WC.

Evid Based Complement Alternat Med. 2017;2017:4695951. doi: 10.1155/2017/4695951. Epub 2017 May 11.


Bright Single-Photon Source at 1.3 μm Based on InAs Bilayer Quantum Dot in Micropillar.

Chen ZS, Ma B, Shang XJ, Ni HQ, Wang JL, Niu ZC.

Nanoscale Res Lett. 2017 Dec;12(1):378. doi: 10.1186/s11671-017-2153-2. Epub 2017 May 31.


Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma.

Wang LL, Chen ZS, Zhou WD, Shu J, Wang XH, Jin R, Zhuang LL, Hoda MA, Zhang H, Zhou GP.

Sci Rep. 2017 May 31;7(1):2551. doi: 10.1038/s41598-017-02700-5. Erratum in: Sci Rep. 2018 Mar 6;8(1):4299.


Uncaria alkaloids reverse ABCB1-mediated cancer multidrug resistance.

Huang BY, Zeng Y, Li YJ, Huang XJ, Hu N, Yao N, Chen MF, Yang ZG, Chen ZS, Zhang DM, Zeng CQ.

Int J Oncol. 2017 Jul;51(1):257-268. doi: 10.3892/ijo.2017.4005. Epub 2017 May 17.


Ionic Liquid as an Efficient Medium for the Synthesis of Quinoline Derivatives via α-Chymotrypsin-Catalyzed Friedländer Condensation.

Le ZG, Liang M, Chen ZS, Zhang SH, Xie ZB.

Molecules. 2017 May 8;22(5). pii: E762. doi: 10.3390/molecules22050762.


Suppression of ABCG2 mediated MDR in vitro and in vivo by a novel inhibitor of ABCG2 drug transport.

Patel A, Li TW, Anreddy N, Wang DS, Sodani K, Gadhia S, Kathawala R, Yang DH, Cheng C, Chen ZS.

Pharmacol Res. 2017 Jul;121:184-193. doi: 10.1016/j.phrs.2017.04.025. Epub 2017 Apr 26.


Effect of Y6, an epigallocatechin gallate derivative, on reversing doxorubicin drug resistance in human hepatocellular carcinoma cells.

Wen Y, Zhao RQ, Zhang YK, Gupta P, Fu LX, Tang AZ, Liu BM, Chen ZS, Yang DH, Liang G.

Oncotarget. 2017 May 2;8(18):29760-29770. doi: 10.18632/oncotarget.15964.


[Establishment of rat model of type 2 diabetes complicated with hypertension].

Huang JX, Chen ZS, Zhang Y, Zhang K, Chen YY, Chen LM, Zhou WW.

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 Apr 8;33(4):329-333. doi: 10.12047/j.cjap.5501.2017.080. Chinese.


Regorafenib overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter in colorectal cancer: In vitro and in vivo study.

Wang YJ, Zhang YK, Zhang GN, Al Rihani SB, Wei MN, Gupta P, Zhang XY, Shukla S, Ambudkar SV, Kaddoumi A, Shi Z, Chen ZS.

Cancer Lett. 2017 Jun 28;396:145-154. doi: 10.1016/j.canlet.2017.03.011. Epub 2017 Mar 14.


Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletion.

Whitt JD, Keeton AB, Gary BD, Sklar LA, Sodani K, Chen ZS, Piazza GA.

J Biomed Res. 2016 Mar;30(2):120-133. doi: 10.7555/JBR.30.20150108. Epub 2015 Nov 20.


GSK1904529A, a Potent IGF-IR Inhibitor, Reverses MRP1-Mediated Multidrug Resistance.

Gupta P, Xie M, Narayanan S, Wang YJ, Wang XQ, Yuan T, Wang Z, Yang DH, Chen ZS.

J Cell Biochem. 2017 Oct;118(10):3260-3267. doi: 10.1002/jcb.25975. Epub 2017 May 3.


The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors.

Zhang H, Patel A, Wang YJ, Zhang YK, Kathawala RJ, Qiu LH, Patel BA, Huang LH, Shukla S, Yang DH, Ambudkar SV, Fu LW, Chen ZS.

Mol Cancer Ther. 2017 Jun;16(6):1021-1030. doi: 10.1158/1535-7163.MCT-16-0511. Epub 2017 Mar 6.


Impact of osmoregulation on the differences in Cd accumulation between two contrasting edible amaranth cultivars grown on Cd-polluted saline soils.

Xu ZM, Li QS, Yang P, Ye HJ, Chen ZS, Guo SH, Wang LL, He BY, Zeng EY.

Environ Pollut. 2017 May;224:89-97. doi: 10.1016/j.envpol.2016.12.067. Epub 2017 Mar 3.


Anticancer Effects of Salvia miltiorrhiza Alcohol Extract on Oral Squamous Carcinoma Cells.

Wang WH, Hsuan KY, Chu LY, Lee CY, Tyan YC, Chen ZS, Tsai WC.

Evid Based Complement Alternat Med. 2017;2017:5364010. doi: 10.1155/2017/5364010. Epub 2017 Jan 29. Erratum in: Evid Based Complement Alternat Med. 2017;2017:4695951.


Selective reversal of BCRP-mediated MDR by VEGFR-2 inhibitor ZM323881.

Zhang YK, Zhang XY, Zhang GN, Wang YJ, Xu H, Zhang D, Shukla S, Liu L, Yang DH, Ambudkar SV, Chen ZS.

Biochem Pharmacol. 2017 May 15;132:29-37. doi: 10.1016/j.bcp.2017.02.019. Epub 2017 Feb 27.


Wind Tunnel Measurements for Flutter of a Long-Afterbody Bridge Deck.

Chen ZS, Zhang C, Wang X, Ma CM.

Sensors (Basel). 2017 Feb 9;17(2). pii: E335. doi: 10.3390/s17020335.

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