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Modeling of Fibrotic Lung Disease Using 3D Organoids Derived from Human Pluripotent Stem Cells.

Strikoudis A, Cieślak A, Loffredo L, Chen YW, Patel N, Saqi A, Lederer DJ, Snoeck HW.

Cell Rep. 2019 Jun 18;27(12):3709-3723.e5. doi: 10.1016/j.celrep.2019.05.077.


GR and LSD1/KDM1A-Targeted Gene Activation Requires Selective H3K4me2 Demethylation at Enhancers.

Clark EA, Wu F, Chen Y, Kang P, Kaiser UB, Fang R, Shi YG.

Cell Rep. 2019 Jun 18;27(12):3522-3532.e3. doi: 10.1016/j.celrep.2019.05.062.


Role of PGRMC1 in cell physiology of cervical cancer.

Shih CC, Chou HC, Chen YJ, Kuo WH, Chan CH, Lin YC, Liao EC, Chang SJ, Chan HL.

Life Sci. 2019 Jun 16. pii: S0024-3205(19)30461-8. doi: 10.1016/j.lfs.2019.06.016. [Epub ahead of print]


Tea Consumption and Health Outcomes: Umbrella Review of Meta-Analyses of Observational Studies in Humans.

Yi M, Wu X, Zhuang W, Xia L, Chen Y, Zhao R, Wan Q, Du L, Zhou Y.

Mol Nutr Food Res. 2019 Jun 19:e1900389. doi: 10.1002/mnfr.201900389. [Epub ahead of print] Review.


Recommendations for the Design of Clinical Drug-Drug Interaction Studies with Itraconazole using a Mechanistic PBPK Model.

Chen Y, Cabalu TD, Callegari E, Einolf H, Liu L, Parrott N, Peters SA, Schuck E, Sharma P, Tracey H, Upreti VV, Zheng M, Zhu AZX, Hall SD.

CPT Pharmacometrics Syst Pharmacol. 2019 Jun 19. doi: 10.1002/psp4.12449. [Epub ahead of print]


Comparison of five clinical scores for assessment of chronic hand eczema.

Wang X, Xu W, Chen Y, Zhang C, Chen L, Lu Y, Li L, Shi W.

J Dermatol. 2019 Jun 19. doi: 10.1111/1346-8138.14988. [Epub ahead of print] No abstract available.


A dual-mode fluorometric/colorimetric sensor for Cu2+ detection based on hybridized carbon dots and gold-silver core-shell nanoparticles.

Chen Y, Lian Y, Huang M, Wei L, Xiao L.

Analyst. 2019 Jun 19. doi: 10.1039/c9an00850k. [Epub ahead of print]


Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials.

Hong X, Yan H, Xie F, Wang K, Wang Q, Huang H, Yang K, Huang S, Zhao T, Wang J, Chen Y, Liu K, Lan X.

J Transl Med. 2019 Jun 18;17(1):204. doi: 10.1186/s12967-019-1955-7.


Hypoglycemic effects of esculeoside A are mediated via activation of AMPK and upregulation of IRS-1.

Yang Z, Zhang L, Liu J, Lu F, Wang L, Chen Y, Li D.

BMC Complement Altern Med. 2019 Jun 18;19(1):136. doi: 10.1186/s12906-019-2543-3.


DNA N6-Methyladenosine modification role in transmitted variations from genomic DNA to RNA in Herrania umbratica.

Luan MW, Chen W, Xing JF, Xiao CL, Chen Y, Xie SQ.

BMC Genomics. 2019 Jun 18;20(1):508. doi: 10.1186/s12864-019-5776-0.


The upregulation of EGFR in the dorsal root ganglion contributes to chronic compression of dorsal root ganglions-induced neuropathic pain in rats.

Wang S, Liu S, Xu L, Zhu X, Liu W, Tian L, Chen Y, Wang Y, Nagendra BVP, Jia S, Liang L, Huo FQ.

Mol Pain. 2019 Jan-Dec;15:1744806919857297. doi: 10.1177/1744806919857297. No abstract available.


Hemophagocytic lymphohistiocytosis in pregnancy: a case report and review of the literature.

Cheng J, Niu J, Wang Y, Wang C, Zhou Q, Chen Y, Zhang Y, Lin J, Di W.

J Obstet Gynaecol. 2019 Jun 19:1-7. doi: 10.1080/01443615.2019.1601168. [Epub ahead of print]


Reactive oxygen species altering the metabolite profile of the marine-derived fungus Dichotomomyces cejpii F31-1.

Shaker S, Sun TT, Wang LY, Ma WZ, Wu DL, Guo YW, Dong J, Chen YX, Zhu LP, Yang DP, Li HJ, Lan WJ.

Nat Prod Res. 2019 Jun 19:1-8. doi: 10.1080/14786419.2019.1611816. [Epub ahead of print]


Functional independence of Taiwanese patients with mucopolysaccharidoses.

Lee CL, Lin HY, Chuang CK, Chiu HC, Tu RY, Huang YH, Hwu WL, Tsai FJ, Chiu PC, Niu DM, Chen YJ, Chao MC, Chang TM, Lin JL, Chang CY, Kao YC, Lin SP.

Mol Genet Genomic Med. 2019 Jun 18:e790. doi: 10.1002/mgg3.790. [Epub ahead of print]


Soluble epoxide hydrolase inhibitor, TUPS, attenuates isoproterenol/angiotensin II-induced cardiac hypertrophy through mammalian target of rapamycin-mediated autophagy inhibition.

Zhang H, Zhang K, Liang J, Yan W, Wu F, Xu W, Wu Z, Chen Y, Pan R, Wu G.

J Pharm Pharmacol. 2019 Jun 18. doi: 10.1111/jphp.13113. [Epub ahead of print]


Development of a Neighborhood Walkability Index for Studying Neighborhood Physical Activity Contexts in Communities across the U.S. over the Past Three Decades.

Rundle AG, Chen Y, Quinn JW, Rahai N, Bartley K, Mooney SJ, Bader MD, Zeleniuch-Jacquotte A, Lovasi GS, Neckerman KM.

J Urban Health. 2019 Jun 18. doi: 10.1007/s11524-019-00370-4. [Epub ahead of print]


Hospital admissions for acute throat and deep neck infections versus tonsillectomy rates in Germany.

Windfuhr JP, Chen YS.

Eur Arch Otorhinolaryngol. 2019 Jun 12. doi: 10.1007/s00405-019-05509-2. [Epub ahead of print]


One-pot synthesis of SiO2-coated Gd2(WO4)3:Yb3+/Ho3+ nanoparticles for simultaneous multi-imaging, temperature sensing and tumor inhibition.

Liu G, Chen Y, Jia M, Sun Z, Ding B, Shao S, Jiang F, Fu Z, Ma P, Lin J.

Dalton Trans. 2019 Jun 19. doi: 10.1039/c9dt01841g. [Epub ahead of print]


Scalable synthesis of self-assembled bimetallic phosphide/N-doped graphene nanoflakes as an efficient electrocatalyst for overall water splitting.

Yang D, Hou W, Lu Y, Zhang W, Chen Y.

Nanoscale. 2019 Jun 19. doi: 10.1039/c9nr03614h. [Epub ahead of print]


Rs2015 Polymorphism in miRNA Target Site of Sirtuin2 Gene Is Associated with the Risk of Parkinson's Disease in Chinese Han Population.

Chen X, Mai H, Chen X, Cai Y, Cheng Q, Chen X, Li X, Fan W, Tang P, Ou M, Yang J, Chen Y, Cui L.

Biomed Res Int. 2019 May 12;2019:1498034. doi: 10.1155/2019/1498034. eCollection 2019.


N-Centered Chiral Self-Sorting and Supramolecular Helix of Tröger's Base-Based Dimeric Macrocycles in Crystalline State.

Chen Y, Cheng M, Hong B, Zhao Q, Qian C, Jiang J, Li S, Lin C, Wang L.

Front Chem. 2019 May 31;7:383. doi: 10.3389/fchem.2019.00383. eCollection 2019.


Duloxetine-Induced Hyponatremia in an Elderly Male Patient with Treatment-Refractory Major Depressive Disorder.

Sun CF, Chen YL, Li YH, Kumaraswamy M, Lo YC, Chen YT.

Case Rep Psychiatry. 2019 May 13;2019:4109150. doi: 10.1155/2019/4109150. eCollection 2019.


A Pilot Study of a Novel through-the-Scope Self-Expandable Metallic Airway Stents Delivery System in Malignant Central Airway Obstruction.

Jiang JH, Zeng DX, Wang CG, Chen YB, Shen D, Mao JY, Turner JF Jr, Huang JA.

Can Respir J. 2019 May 12;2019:7828526. doi: 10.1155/2019/7828526. eCollection 2019.


Heterodera avenae GLAND5 Effector Interacts With Pyruvate Dehydrogenase Subunit of Plant to Promote Nematode Parasitism.

Yang S, Pan L, Chen Y, Yang D, Liu Q, Jian H.

Front Microbiol. 2019 Jun 4;10:1241. doi: 10.3389/fmicb.2019.01241. eCollection 2019.


Research on Factors Affecting the Entrepreneurial Learning From Failure: An Interpretive Structure Model.

Wei J, Chen Y, Zhang J, Gong Y.

Front Psychol. 2019 Jun 4;10:1304. doi: 10.3389/fpsyg.2019.01304. eCollection 2019.


The Optimized Fabrication of a Novel Nanobubble for Tumor Imaging.

Zhang J, Chen Y, Deng C, Zhang L, Sun Z, Wang J, Yang Y, Lv Q, Han W, Xie M.

Front Pharmacol. 2019 May 31;10:610. doi: 10.3389/fphar.2019.00610. eCollection 2019.


SVM-Based Classification of sEMG Signals for Upper-Limb Self-Rehabilitation Training.

Cai S, Chen Y, Huang S, Wu Y, Zheng H, Li X, Xie L.

Front Neurorobot. 2019 Jun 4;13:31. doi: 10.3389/fnbot.2019.00031. eCollection 2019.


Circular RNA hsa_circ_009755 downregulation correlates with clinicopathology in oral squamous cell carcinoma.

Wang Z, Tang J, Wang Y, Sun S, Chen Y, Shen Y, Yang HY.

Onco Targets Ther. 2019 May 23;12:4025-4031. doi: 10.2147/OTT.S196618. eCollection 2019.


Outcomes of laparoscopic cholecystectomy in patients with and without COPD.

Liao KM, Tseng CJ, Chen YC, Wang JJ, Ho CH.

Int J Chron Obstruct Pulmon Dis. 2019 May 27;14:1159-1165. doi: 10.2147/COPD.S201866. eCollection 2019.


Effects of teriparatide in Chinese and Caucasian women with osteoporosis: bridging study on efficacy.

Xie Z, Chen Y, Gurbuz S, Zhang B, Li Y, Bai F, Chen Y.

Clin Interv Aging. 2019 May 27;14:959-968. doi: 10.2147/CIA.S181929. eCollection 2019.


A fractional diffusion random laser.

Chen Y, Fiorentino A, Dal Negro L.

Sci Rep. 2019 Jun 18;9(1):8686. doi: 10.1038/s41598-019-44774-3.


Allicin alleviates lead-induced hematopoietic stem cell aging by upregulating PKM2.

Cai SZ, Zhao LN, Liu J, Ji YT, Shi XY, Ma ZR, Lv XH, Chen K, Chen Y.

Biosci Rep. 2019 Jun 18. pii: BSR20190243. doi: 10.1042/BSR20190243. [Epub ahead of print]


Disrupting LILRB4/APOE interaction by an efficacious humanized antibody reverses T-cell suppression and blocks AML development.

Gui X, Deng M, Song H, Chen Y, Xie J, Li Z, He L, Huang F, Xu Y, Anami Y, Yu H, Yu C, Li L, Yuan Z, Xu X, Wang Q, Chai Y, Huang T, Shi Y, Tsuchikama K, Liao XC, Xia N, Gao GF, Zhang N, Zhang C, An Z.

Cancer Immunol Res. 2019 Jun 18. pii: canimm.0036.2019. doi: 10.1158/2326-6066.CIR-19-0036. [Epub ahead of print]


A Genome-Wide Association Study Identifies Blood Disorder-Related Variants Influencing Hemoglobin A1c With Implications for Glycemic Status in U.S. Hispanics/Latinos.

Moon JY, Louie TL, Jain D, Sofer T, Schurmann C, Below JE, Lai CQ, Aviles-Santa ML, Talavera GA, Smith CE, Petty LE, Bottinger EP, Chen YI, Taylor KD, Daviglus ML, Cai J, Wang T, Tucker KL, Ordovás JM, Hanis CL, Loos RJF, Schneiderman N, Rotter JI, Kaplan RC, Qi Q.

Diabetes Care. 2019 Jun 18. pii: dc190168. doi: 10.2337/dc19-0168. [Epub ahead of print]


Diosgenin exhibits tumor suppressive function via down-regulation of EZH2 in pancreatic cancer cells.

Guo W, Chen Y, Gao J, Zhong K, Wei H, Li K, Tang M, Zhao X, Liu X, Nie C, Yuan Z.

Cell Cycle. 2019 Jun 19. doi: 10.1080/15384101.2019.1632624. [Epub ahead of print]


Knockdown of DANCR reduces osteoclastogenesis and root resorption induced by compression force via Jagged1.

Zhang X, Zhao Y, Zhao Z, Han X, Chen Y.

Cell Cycle. 2019 Jun 19. doi: 10.1080/15384101.2019.1632638. [Epub ahead of print]


Ultrasound-Enhanced Catalytic Ozonation Oxidation of Ammonia in Aqueous Solution.

Liu C, Chen Y, He C, Yin R, Liu J, Qiu T.

Int J Environ Res Public Health. 2019 Jun 17;16(12). pii: E2139. doi: 10.3390/ijerph16122139.


Application of Microfluidic Chips in Separation and Analysis of Extracellular Vesicles in Liquid Biopsy for Cancer.

Lu J, Pang J, Chen Y, Dong Q, Sheng J, Luo Y, Lu Y, Lin B, Liu T.

Micromachines (Basel). 2019 Jun 11;10(6). pii: E390. doi: 10.3390/mi10060390. Review.


E-cadherin is downregulated in benign prostatic hyperplasia and required for tight junction formation and permeability barrier in the prostatic epithelial cell monolayer.

Li F, Pascal LE, Stolz DB, Wang K, Zhou Y, Chen W, Xu Y, Chen Y, Dhir R, Parwani AV, Nelson JB, DeFranco DB, Yoshimura N, Balasubramani GK, Gingrich JR, Maranchie JK, Jacobs BL, Davies BJ, Hrebinko RL, Bigley JD, McBride D, Guo P, He D, Wang Z.

Prostate. 2019 Jun 18. doi: 10.1002/pros.23806. [Epub ahead of print]


Grain size and hydroxyl-coverage dependent tribology of polycrystalline graphene.

Chen Y, Wang S, Xie L, Zhu P, Li R, Peng Q.

Nanotechnology. 2019 Jun 18. doi: 10.1088/1361-6528/ab2a87. [Epub ahead of print]


A novel finding of nalbuphine-6-glucuronide, an active opiate metabolite, possessing potent antinociceptive effects: Synthesis and biological evaluation.

Liang RJ, Lai YH, Kao YT, Yang TH, Chen YL, Wang HJ.

Eur J Med Chem. 2019 Jun 11;178:544-551. doi: 10.1016/j.ejmech.2019.06.028. [Epub ahead of print]


The effectiveness of lumbar drainage in the management of the delayed or recurrent cerebrospinal fluid leaks: a retrospective study of case series in a single center.

Fan S, Chen Y, Cao Y, Liu L, Liu F, Zhang C, Zhou L.

World Neurosurg. 2019 Jun 15. pii: S1878-8750(19)31595-5. doi: 10.1016/j.wneu.2019.06.054. [Epub ahead of print]


Risk Factors of Second Surgery for Adjacent Segment Disease following Anterior Cervical Discectomy and Fusion: a 16-year Cohort Study.

Wu JC, Chang HK, Huang WC, Chen YC.

Int J Surg. 2019 Jun 15. pii: S1743-9191(19)30128-1. doi: 10.1016/j.ijsu.2019.06.002. [Epub ahead of print]


Exercise during pregnancy enhances vascular function via epigenetic repression of CaV1.2 channel in offspring of hypertensive rats.

Li S, Chen Y, Zhang Y, Zhang H, Wu Y, He H, Gong L, Zeng F, Shi L.

Life Sci. 2019 Jun 15:116576. doi: 10.1016/j.lfs.2019.116576. [Epub ahead of print]


Transplantation of Mesenchymal Stem Cells Attenuates Pulmonary Hypertension by Normalizing the EndMT.

Huang J, Lu W, Ouyang H, Chen Y, Zhang C, Luo X, Li M, Shu J, Zheng Q, Chen H, Chen J, Tang H, Sun D, Yuan JX, Yang K, Wang J.

Am J Respir Cell Mol Biol. 2019 Jun 18. doi: 10.1165/rcmb.2018-0165OC. [Epub ahead of print]


Gene Expression Changes Accompanying the Duodenal Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis.

Thiruvengadam SS, OʼMalley M, LaGuardia L, Lopez R, Wang Z, Shadrach BL, Chen Y, Li C, Veigl ML, Barnholtz-Sloan JS, Pai RK, Church JM, Kalady MF, Walsh RM, Burke CA.

Clin Transl Gastroenterol. 2019 Jun 18. doi: 10.14309/ctg.0000000000000053. [Epub ahead of print]


Clinical Implications of Identifying Pathogenic Variants in Individuals With Thoracic Aortic Dissection.

Wolford BN, Hornsby WE, Guo D, Zhou W, Lin M, Farhat L, McNamara J, Driscoll A, Wu X, Schmidt EM, Norton EL, Mathis MR, Ganesh SK, Douville NJ, Brummett CM, Kitzman J, Chen YE, Kim K, Deeb GM, Patel H, Eagle KA, Milewicz DM, J Willer C, Yang B.

Circ Genom Precis Med. 2019 Jun;12(6):e002476. doi: 10.1161/CIRCGEN.118.002476. Epub 2019 Jun 18.


Fully exposed canopy tree and liana branches in a tropical forest differ in mechanic traits but are similar in hydraulic traits.

Zhang L, Chen Y, Ma K, Bongers F, Sterck FJ.

Tree Physiol. 2019 Jun 18. pii: tpz070. doi: 10.1093/treephys/tpz070. [Epub ahead of print]


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