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Items: 49

1.

Time on Therapy for at Least Three Months Correlates with Overall Survival in Metastatic Renal Cell Carcinoma.

Chen VJ, Hernandez-Meza G, Agrawal P, Zhang CA, Xie L, Gong CL, Hoerner CR, Srinivas S, Oermann EK, Fan AC.

Cancers (Basel). 2019 Jul 17;11(7). pii: E1000. doi: 10.3390/cancers11071000.

2.

The 'Achilles Heel' of Metabolism in Renal Cell Carcinoma: Glutaminase Inhibition as a Rational Treatment Strategy.

Hoerner CR, Chen VJ, Fan AC.

Kidney Cancer. 2019 Feb 5;3(1):15-29. doi: 10.3233/KCA-180043. Review.

3.

Preclinical analyses and phase I evaluation of LY2603618 administered in combination with pemetrexed and cisplatin in patients with advanced cancer.

Calvo E, Chen VJ, Marshall M, Ohnmacht U, Hynes SM, Kumm E, Diaz HB, Barnard D, Merzoug FF, Huber L, Kays L, Iversen P, Calles A, Voss B, Lin AB, Dickgreber N, Wehler T, Sebastian M.

Invest New Drugs. 2014 Oct;32(5):955-68. doi: 10.1007/s10637-014-0114-5. Epub 2014 Jun 20.

PMID:
24942404
4.

Five fraction image-guided radiosurgery for primary and recurrent meningiomas.

Oermann EK, Bhandari R, Chen VJ, Lebec G, Gurka M, Lei S, Chen L, Suy S, Azumi N, Berkowitz F, Kalhorn C, McGrail K, Collins BT, Jean WC, Collins SP.

Front Oncol. 2013 Aug 20;3:213. doi: 10.3389/fonc.2013.00213. eCollection 2013.

5.

Hypofractionated stereotactic body radiation therapy as monotherapy for intermediate-risk prostate cancer.

Ju AW, Wang H, Oermann EK, Sherer BA, Uhm S, Chen VJ, Pendharkar AV, Hanscom HN, Kim JS, Lei S, Suy S, Lynch JH, Dritschilo A, Collins SP.

Radiat Oncol. 2013 Jan 31;8:30. doi: 10.1186/1748-717X-8-30.

6.

CyberKnife with Tumor Tracking: An Effective Treatment for High-Risk Surgical Patients with Stage I Non-Small Cell Lung Cancer.

Chen VJ, Oermann E, Vahdat S, Rabin J, Suy S, Yu X, Collins SP, Subramaniam D, Banovac F, Anderson E, Collins BT.

Front Oncol. 2012 Feb 1;2:9. doi: 10.3389/fonc.2012.00009. eCollection 2012.

7.

Role of emotion in shifting choice preference: a neuroscientific perspective.

Chen VJ, Allen H, Deb S, Humphreys G.

Front Psychol. 2011 Nov 15;2:300. doi: 10.3389/fpsyg.2011.00300. eCollection 2011. No abstract available.

8.

Virtual reality and pain management: current trends and future directions.

Li A, Montaño Z, Chen VJ, Gold JI.

Pain Manag. 2011 Mar;1(2):147-157.

9.

Low incidence of new biochemical and clinical hypogonadism following hypofractionated stereotactic body radiation therapy (SBRT) monotherapy for low- to intermediate-risk prostate cancer.

Oermann EK, Suy S, Hanscom HN, Kim JS, Lei S, Yu X, Zhang G, Ennis B, Rohan JP, Piel N, Sherer BA, Borum D, Chen VJ, Batipps GP, Constantinople NL, Dejter SW, Bandi G, Pahira J, McGeagh KG, Adams-Campbell L, Jha R, Dawson NA, Collins BT, Dritschilo A, Lynch JH, Collins SP.

J Hematol Oncol. 2011 Mar 27;4:12. doi: 10.1186/1756-8722-4-12.

10.

Functional magnetic resonance imaging of binocular interactions in visual cortex in strabismus.

Chen VJ, Tarczy-Hornoch K.

J Pediatr Ophthalmol Strabismus. 2011 Nov-Dec;48(6):366-74. doi: 10.3928/01913913-20101118-01. Epub 2010 Nov 23.

PMID:
21117523
11.

A phase I study of pemetrexed in patients with relapsed or refractory acute leukemia.

Abdel-Karim I, Plunkett WK Jr, O'Brien S, Giles F, Thomas D, Faderl S, Ravandi F, Rios MB, Du M, Schneck KB, Chen VJ, Lin BK, Nicol SJ, Kantarjian HM.

Invest New Drugs. 2011 Apr;29(2):323-31. doi: 10.1007/s10637-009-9369-7. Epub 2010 Jan 21.

12.

Comparative evaluation of nanofibrous scaffolding for bone regeneration in critical-size calvarial defects.

Woo KM, Chen VJ, Jung HM, Kim TI, Shin HI, Baek JH, Ryoo HM, Ma PX.

Tissue Eng Part A. 2009 Aug;15(8):2155-62. doi: 10.1089/ten.tea.2008.0433.

13.

Derivation and characterization of monoclonal antibodies against human folypolyglutamate synthetase.

Dotzlaf J, Carpenter J, Luo S, Miles RR, Fisher D, Qian YW, Ehsani M, Wang X, Lin A, McClure DB, Chen VJ, Zuckerman SH.

Hybridoma (Larchmt). 2007 Jun;26(3):155-61.

PMID:
17600497
14.

Vernier acuity of illusory contours defined by motion.

Barraza JF, Chen VJ.

J Vis. 2006 Aug 14;6(9):923-32.

PMID:
17083285
15.

Nano-fibrous scaffolding promotes osteoblast differentiation and biomineralization.

Woo KM, Jun JH, Chen VJ, Seo J, Baek JH, Ryoo HM, Kim GS, Somerman MJ, Ma PX.

Biomaterials. 2007 Jan;28(2):335-43. Epub 2006 Jul 18.

PMID:
16854461
16.

Derivation and characterization of a monoclonal antibody against human glycinamide ribonucleotide formyltransferase.

Dotzlaf J, Carpenter J, Luo S, Roberts EF, Solenberg PJ, Qian YW, Lin A, He X, Sandusky GE, McClure DB, Chen VJ, Zuckerman SH.

Hybridoma (Larchmt). 2006 Jun;25(3):139-44.

PMID:
16796460
17.

Bone regeneration on computer-designed nano-fibrous scaffolds.

Chen VJ, Smith LA, Ma PX.

Biomaterials. 2006 Jul;27(21):3973-9. Epub 2006 Mar 27.

PMID:
16564086
18.

The effect of surface area on the degradation rate of nano-fibrous poly(L-lactic acid) foams.

Chen VJ, Ma PX.

Biomaterials. 2006 Jul;27(20):3708-15. Epub 2006 Mar 7.

PMID:
16519935
19.

A phase II trial of pemetrexed in advanced breast cancer: clinical response and association with molecular target expression.

Gomez HL, Santillana SL, Vallejos CS, Velarde R, Sanchez J, Wang X, Bauer NL, Hockett RD, Chen VJ, Niyikiza C, Hanauske AR.

Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):832-8.

20.

Nano-fibrous poly(L-lactic acid) scaffolds with interconnected spherical macropores.

Chen VJ, Ma PX.

Biomaterials. 2004 May;25(11):2065-73.

PMID:
14741621
21.

Nano-fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment.

Woo KM, Chen VJ, Ma PX.

J Biomed Mater Res A. 2003 Nov 1;67(2):531-7.

PMID:
14566795
22.

Subjective color from apparent motion.

Chen VJ, Cicerone CM.

J Vis. 2002;2(6):424-37.

23.

Depth from subjective color and apparent motion.

Chen VJ, Cicerone CM.

Vision Res. 2002 Aug;42(18):2131-135.

24.

Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.

Schmidt A, Wu H, MacKenzie RE, Chen VJ, Bewly JR, Ray JE, Toth JE, Cygler M.

Biochemistry. 2000 May 30;39(21):6325-35.

PMID:
10828945
25.

An assessment of the antithymine and antipurine characteristics of MTA (LY231514) in CCRF-CEM cells.

Chen VJ, Bewley JR, Smith PG, Andis SL, Schultz RM, Iversen PW, Tonkinson JL, Shih C.

Adv Enzyme Regul. 2000;40:143-54. No abstract available.

PMID:
10828350
26.

Cellular ATP depletion by LY309887 as a predictor of growth inhibition in human tumor cell lines.

Lu X, Errington J, Chen VJ, Curtin NJ, Boddy AV, Newell DR.

Clin Cancer Res. 2000 Jan;6(1):271-7.

PMID:
10656458
27.

Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs.

Schultz RM, Chen VJ, Bewley JR, Roberts EF, Shih C, Dempsey JA.

Semin Oncol. 1999 Apr;26(2 Suppl 6):68-73.

PMID:
10598558
28.

Cellular pharmacology of MTA: a correlation of MTA-induced cellular toxicity and in vitro enzyme inhibition with its effect on intracellular folate and nucleoside triphosphate pools in CCRF-CEM cells.

Chen VJ, Bewley JR, Andis SL, Schultz RM, Iversen PW, Shih C, Mendelsohn LG, Seitz DE, Tonkinson JL.

Semin Oncol. 1999 Apr;26(2 Suppl 6):48-54.

PMID:
10598555
29.

Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis.

Mendelsohn LG, Shih C, Chen VJ, Habeck LL, Gates SB, Shackelford KA.

Semin Oncol. 1999 Apr;26(2 Suppl 6):42-7. Review.

PMID:
10598554
30.

Test of a convergence model for color transparency perception.

Chen VJ, D'Zmura M.

Perception. 1998;27(5):595-608.

PMID:
10070558
31.

The antiproliferative and cell cycle effects of 5,6,7, 8-tetrahydro-N5,N10-carbonylfolic acid, an inhibitor of methylenetetrahydrofolate dehydrogenase, are potentiated by hypoxanthine.

Tonkinson JL, Habeck LL, Toth JE, Mendelsohn LG, Bewley J, Shackelford KA, Gates SB, Ray J, Chen VJ.

J Pharmacol Exp Ther. 1998 Oct;287(1):315-21.

PMID:
9765352
32.

Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA).

Shih C, Habeck LL, Mendelsohn LG, Chen VJ, Schultz RM.

Adv Enzyme Regul. 1998;38:135-52.

PMID:
9762351
33.
34.

Acylation of human insulin with palmitic acid extends the time action of human insulin in diabetic dogs.

Myers SR, Yakubu-Madus FE, Johnson WT, Baker JE, Cusick TS, Williams VK, Tinsley FC, Kriauciunas A, Manetta J, Chen VJ.

Diabetes. 1997 Apr;46(4):637-42.

PMID:
9075804
35.

LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.

Shih C, Chen VJ, Gossett LS, Gates SB, MacKellar WC, Habeck LL, Shackelford KA, Mendelsohn LG, Soose DJ, Patel VF, Andis SL, Bewley JR, Rayl EA, Moroson BA, Beardsley GP, Kohler W, Ratnam M, Schultz RM.

Cancer Res. 1997 Mar 15;57(6):1116-23.

36.

Role of an active site residue analyzed by combination of mutagenesis and coenzyme analog.

Yano T, Hinoue Y, Chen VJ, Metzler DE, Miyahara I, Hirotsu K, Kagamiyama H.

J Mol Biol. 1993 Dec 20;234(4):1218-29.

PMID:
8263922
37.
38.
39.

NMR studies of the active site of isopenicillin N synthase, a non-heme iron(II) enzyme.

Ming LJ, Que L Jr, Kriauciunas A, Frolik CA, Chen VJ.

Biochemistry. 1991 Dec 17;30(50):11653-9.

PMID:
1661145
40.
41.

The functional role of cysteines in isopenicillin N synthase. Correlation of cysteine reactivities toward sulfhydryl reagents with kinetic properties of cysteine mutants.

Kriauciunas A, Frolik CA, Hassell TC, Skatrud PL, Johnson MG, Holbrook NL, Chen VJ.

J Biol Chem. 1991 Jun 25;266(18):11779-88.

42.

Gene disruption of the pcbAB gene encoding ACV synthetase in Cephalosporium acremonium.

Hoskins JA, O'Callaghan N, Queener SW, Cantwell CA, Wood JS, Chen VJ, Skatrud PL.

Curr Genet. 1990 Dec;18(6):523-30.

PMID:
2076552
43.

Spectroscopic studies of isopenicillin N synthase. A mononuclear nonheme Fe2+ oxidase with metal coordination sites for small molecules and substrate.

Chen VJ, Orville AM, Harpel MR, Frolik CA, Surerus KK, Münck E, Lipscomb JD.

J Biol Chem. 1989 Dec 25;264(36):21677-81.

44.

Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans.

Weigel BJ, Burgett SG, Chen VJ, Skatrud PL, Frolik CA, Queener SW, Ingolia TD.

J Bacteriol. 1988 Sep;170(9):3817-26.

45.

Reactions of 3'-O-methylpyridoxal 5'-phosphate in aspartate aminotransferase.

Chen VJ, Metzler DE, Jenkins WT.

J Biol Chem. 1987 Oct 25;262(30):14422-7.

46.

Noncovalent attachment of oligosaccharide-asparagine derivatives to proteins.

Chen VJ.

Methods Enzymol. 1987;138:418-24. No abstract available.

PMID:
3600336
48.
49.

Highly purified mRNA for myosin heavy chain: size and polyadenylic acid content.

Mondal H, Sutton A, Chen VJ, Sarkar S.

Biochem Biophys Res Commun. 1974 Feb 27;56(4):988-96. No abstract available.

PMID:
4826473

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