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Items: 1 to 50 of 2668

1.

Discovery of a covalent inhibitor of KRASG12C (AMG 510) for the treatment of solid tumors.

Lanman BA, Allen JR, Allen JG, Amegadzie AK, Ashton KS, Booker SK, Chen JJ, Chen N, Frohn MJ, Goodman G, Kopecky DJ, Liu L, Lopez P, Low JD, Ma V, Minatti AE, Nguyen TT, Nishimura N, Pickrell AJ, Reed AB, Shin Y, Siegmund A, Tamayo NA, Tegley CM, Walton MC, Wang HL, Wurz RP, Xue M, Yang KC, Achanta P, Bartberger MD, Canon J, Hollis LS, McCarter JD, Mohr C, Rex K, Saiki AY, San Miguel T, Volak L, Wang KH, Whittington DA, Zech SG, Lipford JR, Cee VJ.

J Med Chem. 2019 Dec 10. doi: 10.1021/acs.jmedchem.9b01180. [Epub ahead of print]

PMID:
31820981
2.

Baicalin Is Curative Against Rotavirus Damp Heat Diarrhea by Tuning Colonic Mucosal Barrier and Lung Immune Function.

Shen J, Chen JJ, Zhang BM, Zhao J, Chen L, Ye QY, Ling QH, Chen YY, Zhong ZY, Huang QW.

Dig Dis Sci. 2019 Dec 4. doi: 10.1007/s10620-019-05977-w. [Epub ahead of print]

PMID:
31802384
3.

The 5-Lipoxygenase Inhibitor Zileuton Protects Pressure Overload-Induced Cardiac Remodeling via Activating PPARα.

Wu QQ, Deng W, Xiao Y, Chen JJ, Liu C, Wang J, Guo Y, Duan M, Cai Z, Xie S, Yuan Y, Tang Q.

Oxid Med Cell Longev. 2019 Nov 3;2019:7536803. doi: 10.1155/2019/7536803. eCollection 2019.

4.

AIE/FRET-based versatile PEG-Pep-TPE/DOX nanoparticles for cancer therapy and real-time drug release monitoring.

Wang TT, Wei QC, Zhang ZT, Lin MT, Chen JJ, Zhou Y, Guo NN, Zhong XC, Xu WH, Liu ZX, Han M, Gao JQ.

Biomater Sci. 2019 Nov 28. doi: 10.1039/c9bm01546a. [Epub ahead of print]

PMID:
31777865
5.

The prevalence of HIV among MSM in China: a large-scale systematic analysis.

Dong MJ, Peng B, Liu ZF, Ye QN, Liu H, Lu XL, Zhang B, Chen JJ.

BMC Infect Dis. 2019 Nov 27;19(1):1000. doi: 10.1186/s12879-019-4559-1.

6.

Clinical Characteristics and Treatment of MOG-IgG-Associated Optic Neuritis.

Tajfirouz DA, Bhatti MT, Chen JJ.

Curr Neurol Neurosci Rep. 2019 Nov 26;19(12):100. doi: 10.1007/s11910-019-1014-z. Review.

PMID:
31773369
7.

A Cell Membrane-Targeting Self-Delivery Chimeric Peptide for Enhanced Photodynamic Therapy and In Situ Therapeutic Feedback.

Ma W, Sha SN, Chen PL, Yu M, Chen JJ, Huang CB, Yu B, Liu Y, Liu LH, Yu ZQ.

Adv Healthc Mater. 2019 Nov 25:e1901100. doi: 10.1002/adhm.201901100. [Epub ahead of print]

PMID:
31763796
8.

Solo smart fluorogenic probe for potential cancer diagnosis and tracking in vivo tumorous lymphatic systems via distinct emission signals.

Samanta S, Huang M, Lin F, Das P, Chen B, Yan W, Chen JJ, Ji K, Liu L, Qu J, Yang Z.

Anal Chem. 2019 Nov 25. doi: 10.1021/acs.analchem.9b04834. [Epub ahead of print]

PMID:
31760749
9.

Remediation of arsenic-cationic metals from smelter contaminated soil by washings of Na2EDTA and phosphoric acid: removal efficiencies and mineral transformation.

Wei M, Chen JJ, Xia CH.

Environ Technol. 2019 Dec 1:1-9. doi: 10.1080/09593330.2019.1696413. [Epub ahead of print]

PMID:
31755814
10.

The conserved structure of plant telomerase RNA provides the missing link for an evolutionary pathway from ciliates to humans.

Song J, Logeswaran D, Castillo-González C, Li Y, Bose S, Aklilu BB, Ma Z, Polkhovskiy A, Chen JJ, Shippen DE.

Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24542-24550. doi: 10.1073/pnas.1915312116. Epub 2019 Nov 21.

PMID:
31754031
11.
12.

Therapeutic potential of menstrual blood stem cells in treating acute liver failure.

Cen PP, Fan LX, Wang J, Chen JJ, Li LJ.

World J Gastroenterol. 2019 Nov 7;25(41):6190-6204. doi: 10.3748/wjg.v25.i41.6190.

13.

Clinical phenotype, radiological features, and treatment of myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) optic neuritis.

Chen JJ, Bhatti MT.

Curr Opin Neurol. 2019 Nov 16. doi: 10.1097/WCO.0000000000000766. [Epub ahead of print]

PMID:
31743235
14.

Network pharmacology predicted HDAC6 as a potential target of flavones from Daphne giraldii on hepatocellular carcinoma.

Chen JJ, Shang XY, Han FY, Zhang Y, Zhao D, Yao GD, Song SJ.

Nat Prod Res. 2019 Nov 19:1-5. doi: 10.1080/14786419.2019.1693563. [Epub ahead of print]

PMID:
31741408
15.

Laparoscopic colorectal cancer surgery reduces the adverse impacts of sarcopenia on postoperative outcomes: a propensity score-matched analysis.

Zhang FM, Ma BW, Huang YY, Chen WZ, Chen JJ, Dong QT, Chen WS, Chen XL, Shen X, Yu Z, Zhuang CL.

Surg Endosc. 2019 Nov 18. doi: 10.1007/s00464-019-07249-0. [Epub ahead of print]

PMID:
31741159
16.

Latent trajectories of fluid balance are associated with outcomes in cardiac and aortic surgery.

Kuo G, Chen SW, Lee CC, Chen JJ, Fan PC, Wang SY, Tian YC, Chang CH.

Ann Thorac Surg. 2019 Nov 14. pii: S0003-4975(19)31694-7. doi: 10.1016/j.athoracsur.2019.09.068. [Epub ahead of print]

PMID:
31734247
17.

Decreased local immune response and retained HPV gene expression during chemoradiotherapy are associated with treatment resistance and death from cervical cancer.

Cosper PF, McNair C, González I, Wong N, Knudsen KE, Chen JJ, Markovina S, Schwarz JK, Grigsby PW, Wang X.

Int J Cancer. 2019 Nov 15. doi: 10.1002/ijc.32793. [Epub ahead of print]

PMID:
31732968
19.

Impact of primary tumor-specific growth rate on treatment failure for nonoropharyngeal head and neck cancers.

Roldan CS, Chen JJ, Fareed MM, Hameed MY, Churilla TM, Lango MN, Galloway TJ.

Laryngoscope. 2019 Nov 12. doi: 10.1002/lary.28393. [Epub ahead of print]

PMID:
31714626
20.

Potential association between Fusobacterium nucleatum enrichment on oral mucosal surface and oral lichen planus.

Du GH, Wang YF, Chen JJ, Deng YW, Han XZ, Tang GY.

Oral Dis. 2019 Nov 11. doi: 10.1111/odi.13232. [Epub ahead of print]

PMID:
31710746
21.

[Analysis of the effects and influencing factors of thymectomy for myasthenia gravis].

Pang TB, Huang PW, Cui XZ, Chen JJ, Wang M, Zhao WH, Zhang QY.

Zhonghua Yi Xue Za Zhi. 2019 Nov 5;99(41):3232-3236. doi: 10.3760/cma.j.issn.0376-2491.2019.41.007. Chinese.

PMID:
31694118
22.

Collapsin Response-Mediator Protein 5-Associated Retinitis, Vitritis, and Optic Disc Edema.

Cohen DA, Bhatti MT, Pulido JS, Lennon VA, Dubey D, Flanagan EP, Pittock SJ, Klein CJ, Chen JJ.

Ophthalmology. 2019 Sep 20. pii: S0161-6420(19)32058-5. doi: 10.1016/j.ophtha.2019.09.012. [Epub ahead of print]

PMID:
31676123
23.

Epigenetic modification enhances ergot alkaloid production of Claviceps purpurea.

Chen JJ, Han MY, Gong T, Qiao YM, Yang JL, Zhu P.

Biotechnol Lett. 2019 Dec;41(12):1439-1449. doi: 10.1007/s10529-019-02750-x. Epub 2019 Oct 28.

PMID:
31659576
24.

Coexistence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4 Antibodies in Adult and Pediatric Patients.

Kunchok A, Chen JJ, McKeon A, Mills JR, Flanagan EP, Pittock SJ.

JAMA Neurol. 2019 Oct 28. doi: 10.1001/jamaneurol.2019.3656. [Epub ahead of print] No abstract available.

PMID:
31657826
25.

The effects of tamoxifen on mouse behavior.

Li X, Du ZJ, Chen MQ, Chen JJ, Liang ZM, Ding XT, Zhou M, Li SJ, Li XW, Yang JM, Gao TM.

Genes Brain Behav. 2019 Oct 25:e12620. doi: 10.1111/gbb.12620. [Epub ahead of print]

PMID:
31652391
26.

p-Coumaric-Acid-Containing Adenostemma lavenia Ameliorates Acute Lung Injury by Activating AMPK/Nrf2/HO-1 Signaling and Improving the Anti-oxidant Response.

Chen JJ, Deng JS, Huang CC, Li PY, Liang YC, Chou CY, Huang GJ.

Am J Chin Med. 2019;47(7):1483-1506. doi: 10.1142/S0192415X19500769. Epub 2019 Oct 23.

PMID:
31645126
27.

[Clinicopathological characteristics of type 2 diabetes mellitus complicated with colorectal cancer].

Han ZH, Chen JJ, Feng N, Niu PF, Song C, Gao ZY, Gao QK, Ji DB, Wang WB, Lei FM, Gu J.

Zhonghua Wei Chang Wai Ke Za Zhi. 2019 Oct 25;22(10):966-971. doi: 10.3760/cma.j.issn.1671-0274.2019.10.012. Chinese.

PMID:
31630495
28.

Digit Force Controls and Corresponding Brain Activities in Finger Pressing Performance: A Comparison Between Older Adults and Young Individuals.

Cheng PY, Chieh HF, Lin CJ, Hsu HY, Chen JJ, Kuo LC, Su FC.

J Aging Phys Act. 2019 Oct 17:1-10. doi: 10.1123/japa.2018-0252. [Epub ahead of print]

PMID:
31629354
29.

Infliximab therapy and outcomes in patients with polyarticular juvenile idiopathic arthritis: a single-center study in China.

Liu DW, Chen JJ, Tang XM, Zhang Y, Zhou J.

World J Pediatr. 2019 Oct 14. doi: 10.1007/s12519-019-00316-5. [Epub ahead of print]

PMID:
31612428
30.

MiR-199 inhibits EMT and invasion of hepatoma cells through inhibition of Snail expression.

Zhang HY, Li CH, Wang XC, Luo YQ, Cao XD, Chen JJ.

Eur Rev Med Pharmacol Sci. 2019 Sep;23(18):7884-7891. doi: 10.26355/eurrev_201909_18998.

31.

Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of β-thalassemia.

Matte A, Federti E, Winter M, Koerner A, Harmeier A, Mazer N, Tomka T, Di Paolo ML, Defalco L, Andolfo I, Beneduce E, Iolascon A, Macias-Garcia A, Chen JJ, Janin A, Lebouef C, Turrini F, Brugnara C, De Franceschi L.

JCI Insight. 2019 Nov 14;4(22). pii: 130111. doi: 10.1172/jci.insight.130111.

32.

Absence of gut microbiota affects lipid metabolism in the prefrontal cortex of mice.

Chen JJ, Xie J, Zeng BH, Li WW, Bai SJ, Zhou C, Chen W, Wei H, Xie P.

Neurol Res. 2019 Dec;41(12):1104-1112. doi: 10.1080/01616412.2019.1675021. Epub 2019 Oct 7.

PMID:
31587617
33.

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.

Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M.

J Biol Chem. 2019 Oct 2. pii: jbc.RA119.009432. doi: 10.1074/jbc.RA119.009432. [Epub ahead of print]

34.

Investigation of the Capacitance-Voltage Electrical Characteristics of Thin-Film Transistors Caused by Hydrogen Diffusion under Negative Bias Stress in a Moist Environment.

Chen HC, Kuo CW, Chang TC, Lai WC, Chen PH, Chen GF, Huang SP, Chen JJ, Zhou KJ, Shih CC, Tsao YC, Huang HC, Sze SM.

ACS Appl Mater Interfaces. 2019 Oct 30;11(43):40196-40203. doi: 10.1021/acsami.9b11637. Epub 2019 Oct 15.

PMID:
31573173
35.

Pythium subutonaiense, A New Aquatic Oomycete from Southern China Based on Morphological and Molecular Characters.

Chen JJ, Zheng XB.

Mycobiology. 2019 Aug 8;47(3):273-279. doi: 10.1080/12298093.2019.1642700. eCollection 2019.

36.

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies.

Chen JJ, Zhang S.

Blood. 2019 Nov 14;134(20):1697-1707. doi: 10.1182/blood.2019001915.

PMID:
31554636
37.

Nanoparticle Classification Using Frequency Domain Analysis on Resource-Limited Platforms.

Yayla M, Toma A, Chen KH, Lenssen JE, Shpacovitch V, Hergenröder R, Weichert F, Chen JJ.

Sensors (Basel). 2019 Sep 24;19(19). pii: E4138. doi: 10.3390/s19194138.

38.

Intrinsic Frequencies of the Resting-State fMRI Signal: The Frequency Dependence of Functional Connectivity and the Effect of Mode Mixing.

Yuen NH, Osachoff N, Chen JJ.

Front Neurosci. 2019 Sep 4;13:900. doi: 10.3389/fnins.2019.00900. eCollection 2019.

39.

Klinefelter's syndrome with systemic lupus erythematosus and atrial fibrillation.

Lv J, Feng Y, Qian Y, Chen JJ.

Lupus. 2019 Oct;28(12):1477-1479. doi: 10.1177/0961203319877256. Epub 2019 Sep 24.

PMID:
31551034
40.

DHHC5 Mediates β-Adrenergic Signaling in Cardiomyocytes by Targeting Gα Proteins.

Chen JJ, Marsden AN, Scott CA, Akimzhanov AM, Boehning D.

Biophys J. 2019 Aug 22. pii: S0006-3495(19)30715-5. doi: 10.1016/j.bpj.2019.08.018. [Epub ahead of print]

41.

Identification of immunodominant IgE epitopes of the major house dust mite allergen Der f 24.

Cai ZL, Zhang Z, Luo WL, Hou YB, He YS, Chen JJ, Ji K.

Int J Mol Med. 2019 Nov;44(5):1888-1898. doi: 10.3892/ijmm.2019.4345. Epub 2019 Sep 18.

42.

New 8-Hydroxybriaranes from the Gorgonian Coral Junceella fragilis (Ellisellidae).

Chen YY, Fang LS, Chen YH, Peng BR, Su TP, Huynh TH, Lin FY, Hu CC, Lin NC, Wen ZH, Chen JJ, Lee CY, Wang JW, Sung PJ.

Mar Drugs. 2019 Sep 14;17(9). pii: E534. doi: 10.3390/md17090534.

43.

Gagné's 9 Events of Instruction With Active Learning: Teaching Student Pharmacists How to Measure Blood Pressure.

Chen JJ, Johannesmeyer HJ.

J Pharm Pract. 2019 Sep 16:897190019875610. doi: 10.1177/0897190019875610. [Epub ahead of print]

PMID:
31526081
44.

Requirement of activating transcription factor 5 for murine fetal liver erythropoiesis.

Zhang S, Chen JJ.

Br J Haematol. 2019 Sep 16. doi: 10.1111/bjh.16202. [Epub ahead of print]

PMID:
31524288
45.

Labdane-Type Diterpenoids from Leonurus japonicus and Their Plant-Growth Regulatory Activity.

Li HY, Peng X, Jin X, Wei WJ, Ma KL, Li Y, Chen JJ, Gao K.

J Nat Prod. 2019 Sep 27;82(9):2568-2579. doi: 10.1021/acs.jnatprod.9b00422. Epub 2019 Sep 10.

PMID:
31503485
46.

a Novel Approach to Accumulate Superparamagnetic Particles in Aqueous Environment using Time-Varying Magnetic Field.

Liu YL, Chen JJ, Ahmad F, Zhang TD, Guo WH, Ye YJ, Shang P, Yin DC.

IEEE Trans Biomed Eng. 2019 Sep 9. doi: 10.1109/TBME.2019.2940029. [Epub ahead of print]

PMID:
31502959
47.

Age-specific urinary metabolite signatures and functions in patients with major depressive disorder.

Chen JJ, Xie J, Li WW, Bai SJ, Wang W, Zheng P, Xie P.

Aging (Albany NY). 2019 Sep 6;11(17):6626-6637. doi: 10.18632/aging.102133. Epub 2019 Sep 6.

48.

Dynamic programming and automated segmentation of optical coherence tomography images of the neonatal subglottis: enabling efficient diagnostics to manage subglottic stenosis.

Kozlowski KM, Sharma GK, Chen JJ, Qi L, Osann K, Jing JC, Ahuja GS, Heidari AE, Chung PS, Kim S, Chen Z, Wong BJ.

J Biomed Opt. 2019 Sep;24(9):1-8. doi: 10.1117/1.JBO.24.9.096001.

49.

RBM4 modulates the proliferation and expression of inflammatory factors via the alternative splicing of regulatory factors in HeLa cells.

Wang WY, Quan W, Yang F, Wei YX, Chen JJ, Yu H, Xie J, Zhang Y, Li ZF.

Mol Genet Genomics. 2019 Sep 5. doi: 10.1007/s00438-019-01606-3. [Epub ahead of print]

PMID:
31489484
50.

Single-molecule and -particle probing crystal edge/corner as highly efficient photocatalytic sites on a single TiO2 particle.

Wang WK, Chen JJ, Lou ZZ, Kim S, Fujitsuka M, Yu HQ, Majima T.

Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):18827-18833. doi: 10.1073/pnas.1907122116. Epub 2019 Sep 4.

PMID:
31484775

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