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Trend of HIV transmitted drug resistance before and after implementation of HAART regimen restriction in the treatment of HIV-1 infected patients in southern Taiwan.

Weng YW, Chen IT, Tsai HC, Wu KS, Tseng YT, Sy CL, Chen JK, Lee SS, Chen YS.

BMC Infect Dis. 2019 Aug 23;19(1):741. doi: 10.1186/s12879-019-4389-1.


Recent progress in near-field nanolithography using light interactions with colloidal particles: from nanospheres to three-dimensional nanostructures.

Zhang XA, Chen IT, Chang CH.

Nanotechnology. 2019 Aug 30;30(35):352002. doi: 10.1088/1361-6528/ab2282. Epub 2019 May 17.


Deep Brain Stimulation Modified Autism-Like Deficits via the Serotonin System in a Valproic Acid-Induced Rat Model.

Wu HF, Chen YJ, Chu MC, Hsu YT, Lu TY, Chen IT, Chen PS, Lin HC.

Int J Mol Sci. 2018 Sep 19;19(9). pii: E2840. doi: 10.3390/ijms19092840.


HIV-1 genotypic drug resistance in patients with virological failure to single-tablet antiretroviral regimens in southern Taiwan.

Tsai HC, Chen IT, Lee SS, Chen YS.

Infect Drug Resist. 2018 Aug 3;11:1061-1071. doi: 10.2147/IDR.S165811. eCollection 2018.


HIV-1 integrase strand-transfer inhibitor resistance in southern Taiwan.

Tsai HC, Chen IT, Wu KS, Tseng YT, Sy CL, Chen JK, Lee SS, Chen YS.

Oncotarget. 2018 May 18;9(38):24927-24935. doi: 10.18632/oncotarget.24837. eCollection 2018 May 18.


Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus.

Wu HF, Chen YJ, Wu SZ, Lee CW, Chen IT, Lee YC, Huang CC, Hsing CH, Tang CW, Lin HC.

Neural Plast. 2017;2017:3467805. doi: 10.1155/2017/3467805. Epub 2017 Aug 24.


High rate of HIV-1 drug resistance in treatment failure patients in Taiwan, 2009-2014.

Tsai HC, Chen IT, Wu KS, Tseng YT, Sy CL, Chen JK, Lee SS, Chen YS.

Infect Drug Resist. 2017 Oct 16;10:343-352. doi: 10.2147/IDR.S146584. eCollection 2017.


Impact of Different National Ethical Requirements on Ethnographic Patient Safety Studies.

Weicht K, Chen IT.

J Patient Saf. 2018 Sep;14(3):e38. doi: 10.1097/PTS.0000000000000424. No abstract available.


Shrimp miR-10a Is Co-opted by White Spot Syndrome Virus to Increase Viral Gene Expression and Viral Replication.

Huang JY, Kang ST, Chen IT, Chang LK, Lin SS, Kou GH, Chu CY, Lo CF.

Front Immunol. 2017 Sep 6;8:1084. doi: 10.3389/fimmu.2017.01084. eCollection 2017.


Cascaded exciton energy transfer in a monolayer semiconductor lateral heterostructure assisted by surface plasmon polariton.

Shi J, Lin MH, Chen IT, Mohammadi Estakhri N, Zhang XQ, Wang Y, Chen HY, Chen CA, Shih CK, Alù A, Li X, Lee YH, Gwo S.

Nat Commun. 2017 Jun 26;8(1):35. doi: 10.1038/s41467-017-00048-y.


Suppression of LPS-induced inflammatory responses by the hydroxyl groups of dexamethasone.

Chuang TY, Cheng AJ, Chen IT, Lan TY, Huang IH, Shiau CW, Hsu CL, Liu YW, Chang ZF, Tseng PH, Kuo JC.

Oncotarget. 2017 Jul 25;8(30):49735-49748. doi: 10.18632/oncotarget.17683.


Alleviation of N-Methyl-D-Aspartate Receptor-Dependent Long-Term Depression via Regulation of the Glycogen Synthase Kinase-3β Pathway in the Amygdala of a Valproic Acid-Induced Animal Model of Autism.

Wu HF, Chen PS, Chen YJ, Lee CW, Chen IT, Lin HC.

Mol Neurobiol. 2017 Sep;54(7):5264-5276. doi: 10.1007/s12035-016-0074-1. Epub 2016 Aug 30.


Six Hours after Infection, the Metabolic Changes Induced by WSSV Neutralize the Host's Oxidative Stress Defenses.

Chen IT, Lee DY, Huang YT, Kou GH, Wang HC, Chang GD, Lo CF.

Sci Rep. 2016 Jun 9;6:27732. doi: 10.1038/srep27732.


Stability Limit of Water by Metastable Vapor-Liquid Equilibrium with Nanoporous Silicon Membranes.

Chen IT, Sessoms DA, Sherman Z, Choi E, Vincent O, Stroock AD.

J Phys Chem B. 2016 Jun 16;120(23):5209-22. doi: 10.1021/acs.jpcb.6b01618. Epub 2016 Jun 8.


Pathogenesis of acute hepatopancreatic necrosis disease (AHPND) in shrimp.

Lai HC, Ng TH, Ando M, Lee CT, Chen IT, Chuang JC, Mavichak R, Chang SH, Yeh MD, Chiang YA, Takeyama H, Hamaguchi HO, Lo CF, Aoki T, Wang HC.

Fish Shellfish Immunol. 2015 Dec;47(2):1006-14. doi: 10.1016/j.fsi.2015.11.008. Epub 2015 Nov 6.


The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin.

Lee CT, Chen IT, Yang YT, Ko TP, Huang YT, Huang JY, Huang MF, Lin SJ, Chen CY, Lin SS, Lightner DV, Wang HC, Wang AH, Wang HC, Hor LI, Lo CF.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10798-803. doi: 10.1073/pnas.1503129112. Epub 2015 Aug 10. Erratum in: Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):E5445. Lin, Shih-Shuen [corrected to Lin, Shih-Shun].


Beamformer-based spatiotemporal imaging of linearly-related source components using electromagnetic neural signals.

Chan HL, Chen LF, Chen IT, Chen YS.

Neuroimage. 2015 Jul 1;114:1-17. doi: 10.1016/j.neuroimage.2015.03.038. Epub 2015 Mar 21.


Cost-effectiveness analysis of malaria rapid diagnostic test incentive schemes for informal private healthcare providers in Myanmar.

Chen IT, Aung T, Thant HN, Sudhinaraset M, Kahn JG.

Malar J. 2015 Feb 5;14:55. doi: 10.1186/s12936-015-0569-7.


Trends in bilateral salpingo-oophorectomy among Taiwanese women undergoing benign hysterectomy: a population-based, pooled, cross-sectional study.

Lai JC, Huang N, Wang KL, Hu HY, Chen IT, Chou YJ.

Menopause. 2015 Jul;22(7):765-72. doi: 10.1097/GME.0000000000000360.


Trends and outcome predictors after traumatic brain injury surgery: a nationwide population-based study in Taiwan.

Shi HY, Hwang SL, Lee IC, Chen IT, Lee KT, Lin CL.

J Neurosurg. 2014 Dec;121(6):1323-30. doi: 10.3171/2014.8.JNS131526. Epub 2014 Oct 3.


Draft Genome Sequences of Four Strains of Vibrio parahaemolyticus, Three of Which Cause Early Mortality Syndrome/Acute Hepatopancreatic Necrosis Disease in Shrimp in China and Thailand.

Yang YT, Chen IT, Lee CT, Chen CY, Lin SS, Hor LI, Tseng TC, Huang YT, Sritunyalucksana K, Thitamadee S, Wang HC, Lo CF.

Genome Announc. 2014 Sep 4;2(5). pii: e00816-14. doi: 10.1128/genomeA.00816-14.


Targeting Plasmodium falciparum transmission with primaquine: same efficacy, improved safety with a lower dose?

Chen IT, Gosling RD.

Expert Rev Clin Pharmacol. 2014 Nov;7(6):681-6. doi: 10.1586/17512433.2014.948421. Epub 2014 Aug 13.


SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma.

Su JC, Tseng PH, Wu SH, Hsu CY, Tai WT, Li YS, Chen IT, Liu CY, Chen KF, Shiau CW.

Neoplasia. 2014 Jul;16(7):595-605. doi: 10.1016/j.neo.2014.06.005. Epub 2014 Jul 18.


An invertebrate Warburg effect: a shrimp virus achieves successful replication by altering the host metabolome via the PI3K-Akt-mTOR pathway.

Su MA, Huang YT, Chen IT, Lee DY, Hsieh YC, Li CY, Ng TH, Liang SY, Lin SY, Huang SW, Chiang YA, Yu HT, Khoo KH, Chang GD, Lo CF, Wang HC.

PLoS Pathog. 2014 Jun 12;10(6):e1004196. doi: 10.1371/journal.ppat.1004196. eCollection 2014 Jun.


Total synthesis of sandresolide B and amphilectolide.

Chen IT, Baitinger I, Schreyer L, Trauner D.

Org Lett. 2014 Jan 3;16(1):166-9. doi: 10.1021/ol403156r. Epub 2013 Dec 5.


Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo.

Deu E, Chen IT, Lauterwasser EM, Valderramos J, Li H, Edgington LE, Renslo AR, Bogyo M.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18244-9. doi: 10.1073/pnas.1312782110. Epub 2013 Oct 21.


Penaeus monodon thioredoxin restores the DNA binding activity of oxidized white spot syndrome virus IE1.

Huang JY, Liu WJ, Wang HC, Lee DY, Leu JH, Wang HC, Tsai MH, Kang ST, Chen IT, Kou GH, Chang GD, Lo CF.

Antioxid Redox Signal. 2012 Sep 15;17(6):914-26. doi: 10.1089/ars.2011.4264. Epub 2012 Apr 16.


Long-term prediction of emergency department revenue and visitor volume using autoregressive integrated moving average model.

Chen CF, Ho WH, Chou HY, Yang SM, Chen IT, Shi HY.

Comput Math Methods Med. 2011;2011:395690. doi: 10.1155/2011/395690. Epub 2011 Dec 4.


White spot syndrome virus induces metabolic changes resembling the warburg effect in shrimp hemocytes in the early stage of infection.

Chen IT, Aoki T, Huang YT, Hirono I, Chen TC, Huang JY, Chang GD, Lo CF, Wang HC.

J Virol. 2011 Dec;85(24):12919-28. doi: 10.1128/JVI.05385-11. Epub 2011 Oct 5.


Heterogeneous nuclear ribonucleoprotein hrp36 acts as an alternative splicing repressor in Litopenaeus vannamei Dscam.

Lee CW, Chen IT, Chou PH, Hung HY, Wang KV.

Dev Comp Immunol. 2012 Jan;36(1):10-20. doi: 10.1016/j.dci.2011.05.006. Epub 2011 May 31.


Penaeus monodon TATA box-binding protein interacts with the white spot syndrome virus transactivator IE1 and promotes its transcriptional activity.

Liu WJ, Chang YS, Huang WT, Chen IT, Wang KC, Kou GH, Lo CF.

J Virol. 2011 Jul;85(13):6535-47. doi: 10.1128/JVI.02433-10. Epub 2011 Apr 20.


Penaeus monodon Dscam (PmDscam) has a highly diverse cytoplasmic tail and is the first membrane-bound shrimp Dscam to be reported.

Chou PH, Chang HS, Chen IT, Lee CW, Hung HY, Han-Ching Wang KC.

Fish Shellfish Immunol. 2011 Apr-May;30(4-5):1109-23. doi: 10.1016/j.fsi.2011.02.009. Epub 2011 Feb 19.


RNAi knock-down of the Litopenaeus vannamei Toll gene (LvToll) significantly increases mortality and reduces bacterial clearance after challenge with Vibrio harveyi.

Han-Ching Wang K, Tseng CW, Lin HY, Chen IT, Chen YH, Chen YM, Chen TY, Yang HL.

Dev Comp Immunol. 2010 Jan;34(1):49-58. doi: 10.1016/j.dci.2009.08.003. Epub 2009 Aug 27.


The putative invertebrate adaptive immune protein Litopenaeus vannamei Dscam (LvDscam) is the first reported Dscam to lack a transmembrane domain and cytoplasmic tail.

Chou PH, Chang HS, Chen IT, Lin HY, Chen YM, Yang HL, Wang KC.

Dev Comp Immunol. 2009 Dec;33(12):1258-67. doi: 10.1016/j.dci.2009.07.006. Epub 2009 Aug 5.


Suppression of transcription factor early growth response 1 reduces herpes simplex virus lethality in mice.

Chen SH, Yao HW, Chen IT, Shieh B, Li C, Chen SH.

J Clin Invest. 2008 Oct;118(10):3470-7. doi: 10.1172/JCI35114.


Total synthesis of (-)-archazolid B.

Roethle PA, Chen IT, Trauner D.

J Am Chem Soc. 2007 Jul 25;129(29):8960-1. Epub 2007 Jun 27. No abstract available.


Structural role of zinc ions bound to postsynaptic densities.

Jan HH, Chen IT, Tsai YY, Chang YC.

J Neurochem. 2002 Nov;83(3):525-34.


Excavatolides U-Z, new briarane diterpenes from the gorgonian briareum excavatum

Sheu JH, Sung PJ, Su JH, Wang GH, Duh CY, Shen YC, Chiang MY, Chen IT.

J Nat Prod. 1999 Oct;62(10):1415-20.


Interprotein disulfide bonds formed during isolation process tighten the structure of the postsynaptic density.

Lai SL, Chiang SF, Chen IT, Chow WY, Chang YC.

J Neurochem. 1999 Nov;73(5):2130-8.


Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding.

Zhan Q, Chen IT, Antinore MJ, Fornace AJ Jr.

Mol Cell Biol. 1998 May;18(5):2768-78. Erratum in: Mol Cell Biol 1998 Sep;18(9):5620.


Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction.

Chen IT, Akamatsu M, Smith ML, Lung FD, Duba D, Roller PP, Fornace AJ Jr, O'Connor PM.

Oncogene. 1996 Feb 1;12(3):595-607.


Direct interaction of Gadd45 with PCNA and evidence for competitive interaction of Gadd45 and p21Waf1/Cip1 with PCNA.

Chen IT, Smith ML, O'Connor PM, Fornace AJ Jr.

Oncogene. 1995 Nov 16;11(10):1931-7.


Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage.

Smith ML, Chen IT, Zhan Q, O'Connor PM, Fornace AJ Jr.

Oncogene. 1995 Mar 16;10(6):1053-9.


Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.

Smith ML, Chen IT, Zhan Q, Bae I, Chen CY, Gilmer TM, Kastan MB, O'Connor PM, Fornace AJ Jr.

Science. 1994 Nov 25;266(5189):1376-80.


Large exon size does not limit splicing in vivo.

Chen IT, Chasin LA.

Mol Cell Biol. 1994 Mar;14(3):2140-6.


The transcriptionally active human ribosomal protein S17 gene.

Chen IT, Roufa DJ.

Gene. 1988 Oct 15;70(1):107-16.


Ribosomal protein S14 is encoded by a pair of highly conserved, adjacent genes on the X chromosome of Drosophila melanogaster.

Brown SJ, Rhoads DD, Stewart MJ, Van Slyke B, Chen IT, Johnson TK, Denell RE, Roufa DJ.

Mol Cell Biol. 1988 Oct;8(10):4314-21.

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