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The FKH domain in FOXP3 mRNA frequently contains mutations in hepatocellular carcinoma that influence the subcellular localization and functions of FOXP3.

Ren J, Liu Y, Wang S, Wang Y, Li W, Chen S, Cui D, Yang S, Li MY, Feng B, Lai PBS, Chen GG.

J Biol Chem. 2020 Mar 20. pii: jbc.RA120.012518. doi: 10.1074/jbc.RA120.012518. [Epub ahead of print]


FOXP3Δ3, the major isoform of FOXP3, promotes proliferation, migration, and invasion in non-small cell lung cancer.

Jia H, Qi H, Peng J, Li M, Chen GG.

Ann Oncol. 2019 Apr;30 Suppl 2:ii5-ii6. doi: 10.1093/annonc/mdz072.017. No abstract available.


The permissive role of TCTP in PM2.5/NNK-induced epithelial-mesenchymal transition in lung cells.

Liu LZ, Wang M, Xin Q, Wang B, Chen GG, Li MY.

J Transl Med. 2020 Feb 11;18(1):66. doi: 10.1186/s12967-020-02256-5.


Temperature-induced solid-to-solid transformation in helical homochiral coordination polymers.

Xu ZX, Chen GG, Li LF.

Acta Crystallogr C Struct Chem. 2020 Feb 1;76(Pt 2):125-132. doi: 10.1107/S2053229620000182. Epub 2020 Jan 16.


Lipid oversupply induces CD36 sarcolemmal translocation via dual modulation of PKCζ and TBC1D1: an early event prior to insulin resistance.

Zhu B, Li MY, Lin Q, Liang Z, Xin Q, Wang M, He Z, Wang X, Wu X, Chen GG, Tong PC, Zhang W, Liu LZ.

Theranostics. 2020 Jan 1;10(3):1332-1354. doi: 10.7150/thno.40021. eCollection 2020.


[Room tilt illusion: a chief complaint need to be alert in otology clinic].

Wang N, Zhang CM, Gao W, Chen GG.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Dec;33(12):1125-1129. doi: 10.13201/j.issn.1001-1781.2019.12.003. Chinese.


ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway.

Wang N, Li MY, Liu Y, Yu J, Ren J, Zheng Z, Wang S, Yang S, Yang SL, Liu LP, Hu BG, Chong CC, Merchant JL, Lai PB, Chen GG.

Cancer Lett. 2020 Mar 1;472:70-80. doi: 10.1016/j.canlet.2019.12.026. Epub 2019 Dec 23.


Special Issue on the International Symposium on Biological Polymers 2018.

Rehm BHA, Chen GG.

Biotechnol J. 2019 Dec;14(12):e1900500. doi: 10.1002/biot.201900500. No abstract available.


Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants.

Ju C, Fiori LM, Belzeaux R, Theroux JF, Chen GG, Aouabed Z, Blier P, Farzan F, Frey BN, Giacobbe P, Lam RW, Leri F, MacQueen GM, Milev R, Müller DJ, Parikh SV, Rotzinger S, Soares CN, Uher R, Li Q, Foster JA, Kennedy SH, Turecki G.

Transl Psychiatry. 2019 Oct 8;9(1):254. doi: 10.1038/s41398-019-0589-0.


[How to initially screen common central "malignant vertigo" at the bedside?]

Chen GG, Zhang CM, Gao W, Fan HR, Huangfu H, Wang BQ.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Aug 7;54(8):631-637. doi: 10.3760/cma.j.issn.1673-0860.2019.08.017. Chinese.


Ambient fine particulate matter inhibits 15-lipoxygenases to promote lung carcinogenesis.

Li MY, Liu LZ, Li W, Ng CSH, Liu Y, Kong AWY, Zhao Z, Wang S, Qi H, Jia H, Yang S, Du J, Long X, Ho RLK, Chak ECW, Wan IYP, Mok TSK, Underwood MJ, Gali NK, Ning Z, Chen GG.

J Exp Clin Cancer Res. 2019 Aug 16;38(1):359. doi: 10.1186/s13046-019-1380-z.


EGFR-AS1/HIF2A regulates the expression of FOXP3 to impact the cancer stemness of smoking-related non-small cell lung cancer.

Qi H, Wang S, Wu J, Yang S, Gray S, Ng CSH, Du J, Underwood MJ, Li MY, Chen GG.

Ther Adv Med Oncol. 2019 Jun 13;11:1758835919855228. doi: 10.1177/1758835919855228. eCollection 2019.


[Clinical characteristics of LC-BPPV patients with bilateral direction-fixed horizontal nystagmus in primary Roll test].

Chen GG, Zhang CM, Gao W, Fan HR, HuangFu H, Yu WY, Zheng ZY, Yang J, Wang BQ.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jun;33(6):489-492. doi: 10.13201/j.issn.1001-1781.2019.06.003. Chinese.


Genome-Wide Screening and Functional Analysis Identifies Tumor Suppressor Long Noncoding RNAs Epigenetically Silenced in Hepatocellular Carcinoma.

Xu F, Li CH, Wong CH, Chen GG, Lai PBS, Shao S, Chan SL, Chen Y.

Cancer Res. 2019 Apr 1;79(7):1305-1317. doi: 10.1158/0008-5472.CAN-18-1659. Epub 2019 Feb 4.


PES1 promotes the occurrence and development of papillary thyroid cancer by upregulating the ERα/ERβ protein ratio.

Qiu YB, Liao LY, Jiang R, Xu M, Xu LW, Chen GG, Liu ZM.

Sci Rep. 2019 Jan 31;9(1):1032. doi: 10.1038/s41598-018-37648-7.


Correction: A new microdeletion syndrome involving TBC1D24, ATP6V0C, and PDPK1 causes epilepsy, microcephaly, and developmental delay.

Mucha BE, Banka S, Ajeawung NF, Molidperee S, Chen GG, Koenig MK, Adejumo RB, Till M, Harbord M, Perrier R, Lemyre E, Boucher RM, Skotko BG, Waxler JL, Thomas MA, Hodge JC, Gecz J, Nicholl J, McGregor L, Linden T, Sisodiya SM, Sanlaville D, Cheung SW, Ernst C, Campeau PM.

Genet Med. 2019 Sep;21(9):2159-2160. doi: 10.1038/s41436-018-0413-x.


The expression of FOXP3 and its role in human cancers.

Jia H, Qi H, Gong Z, Yang S, Ren J, Liu Y, Li MY, Chen GG.

Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):170-178. doi: 10.1016/j.bbcan.2018.12.004. Epub 2019 Jan 7. Review.


Cancer stem cells in hepatocellular carcinoma: an overview and promising therapeutic strategies.

Wang N, Wang S, Li MY, Hu BG, Liu LP, Yang SL, Yang S, Gong Z, Lai PBS, Chen GG.

Ther Adv Med Oncol. 2018 Dec 21;10:1758835918816287. doi: 10.1177/1758835918816287. eCollection 2018. Review.


Homology-independent multiallelic disruption via CRISPR/Cas9-based knock-in yields distinct functional outcomes in human cells.

Zhang C, He X, Kwok YK, Wang F, Xue J, Zhao H, Suen KW, Wang CC, Ren J, Chen GG, Lai PBS, Li J, Xia Y, Chan AM, Chan WY, Feng B.

BMC Biol. 2018 Dec 28;16(1):151. doi: 10.1186/s12915-018-0616-2.


[The clinical characteristics of the evoked nystagmus in the non-affected side during Dix-Hallpike test in the unilateral posterior semicircular canal benign paroxysmal positional vertigo].

Xiong BB, Lin CM, Lin YF, Liu J, Chen GG.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Oct 5;32(19):1451-1454. doi: 10.13201/j.issn.1001-1781.2018.19.002. Chinese.


An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals.

Carbonell P, Jervis AJ, Robinson CJ, Yan C, Dunstan M, Swainston N, Vinaixa M, Hollywood KA, Currin A, Rattray NJW, Taylor S, Spiess R, Sung R, Williams AR, Fellows D, Stanford NJ, Mulherin P, Le Feuvre R, Barran P, Goodacre R, Turner NJ, Goble C, Chen GG, Kell DB, Micklefield J, Breitling R, Takano E, Faulon JL, Scrutton NS.

Commun Biol. 2018 Jun 8;1:66. doi: 10.1038/s42003-018-0076-9. eCollection 2018.


A new microdeletion syndrome involving TBC1D24, ATP6V0C, and PDPK1 causes epilepsy, microcephaly, and developmental delay.

Mucha BE, Banka S, Ajeawung NF, Molidperee S, Chen GG, Koenig MK, Adejumo RB, Till M, Harbord M, Perrier R, Lemyre E, Boucher RM, Skotko BG, Waxler JL, Thomas MA, Hodge JC, Gecz J, Nicholl J, McGregor L, Linden T, Sisodiya SM, Sanlaville D, Cheung SW, Ernst C, Campeau PM.

Genet Med. 2019 May;21(5):1058-1064. doi: 10.1038/s41436-018-0290-3. Epub 2018 Sep 24. Erratum in: Genet Med. 2019 Jan 14;:.


Treatment Patterns in Veterans with Laryngeal and Oropharyngeal Cancer and Impact on Survival.

Richardson PA, Kansara S, Chen GG, Sabichi A, Sikora AG, Parke RB, Donovan DT, Chiao E, Sandulache VC.

Laryngoscope Investig Otolaryngol. 2018 Aug 9;3(4):275-282. doi: 10.1002/lio2.170. eCollection 2018 Aug.


Novel method for rapid identification of micropapillary or solid components in early-stage lung adenocarcinoma.

Zhao ZR, Lau RWH, Long H, Mok TSK, Chen GG, Underwood MJ, Ng CSH.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2310-2318.e2. doi: 10.1016/j.jtcvs.2018.07.054. Epub 2018 Aug 2.


ID1-induced p16/IL6 axis activation contributes to the resistant of hepatocellular carcinoma cells to sorafenib.

Niu LL, Cheng CL, Li MY, Yang SL, Hu BG, Chong CCN, Chan SL, Ren J, Chen GG, Lai PBS.

Cell Death Dis. 2018 Aug 28;9(9):852. doi: 10.1038/s41419-018-0926-x.


Novel HDAC5-interacting motifs of Tbx3 are essential for the suppression of E-cadherin expression and for the promotion of metastasis in hepatocellular carcinoma.

Dong L, Dong Q, Chen Y, Li Y, Zhang B, Zhou F, Lyu X, Chen GG, Lai P, Kung HF, He ML.

Signal Transduct Target Ther. 2018 Aug 24;3:22. doi: 10.1038/s41392-018-0025-6. eCollection 2018.


Targeting ZBP-89 for the treatment of hepatocellular carcinoma.

Wang N, Wang S, Yang SL, Liu LP, Li MY, Lai PBS, Chen GG.

Expert Opin Ther Targets. 2018 Oct;22(10):817-822. doi: 10.1080/14728222.2018.1516753. Epub 2018 Sep 6. Review.


XPG rs873601 G>A contributes to uterine leiomyoma susceptibility in a Southern Chinese population.

Liu ZQ, Chen GG, Sun RL, Chen C, Lu MY, Guan LF, Chi XL, Jian YQ, Zhu X, Liu RQ, Cai BY, Chen FF, Liu B.

Biosci Rep. 2018 Sep 13;38(5). pii: BSR20181116. doi: 10.1042/BSR20181116. Print 2018 Oct 31.


MicroRNA-125b Interacts with Foxp3 to Induce Autophagy in Thyroid Cancer.

Wang S, Wu J, Ren J, Vlantis AC, Li MY, Liu SYW, Ng EKW, Chan ABW, Luo DC, Liu Z, Guo W, Xue L, Ng SK, van Hasselt CA, Tong MCF, Chen GG.

Mol Ther. 2018 Sep 5;26(9):2295-2303. doi: 10.1016/j.ymthe.2018.06.015. Epub 2018 Jun 21.


Evidence of Reduced Agmatine Concentrations in the Cerebral Cortex of Suicides.

Chen GG, Almeida D, Fiori L, Turecki G.

Int J Neuropsychopharmacol. 2018 Oct 1;21(10):895-900. doi: 10.1093/ijnp/pyy058.


[Characteristics and Risks of Heavy Metals Content in Surface Sediment of Tidal Flat Areas in Eastern China].

Zhang M, Bao ZY, Chen GG, Yong TJ, Zhu YP, Liang XH.

Huan Jing Ke Xue. 2017 Nov 8;38(11):4513-4524. doi: 10.13227/j.hjkx.201701199. Chinese.


Carfilzomib combined with ex vivo-expanded patient autologous natural killer cells for myeloma immunotherapy.

Chang SK, Hou J, Chen GG, Yu DD, Wu HQ, Xie YS, Hu LN, Gao L, Xiao WQ, Kong YY, Tao Y, Shi JM.

Neoplasma. 2018 Sep 19;65(5):720-729. doi: 10.4149/neo_2018_171019N668. Epub 2018 Jun 18.


[Expression and significance of serum hepatocyte growth factor and myeloperoxidase in patients with obstructive sleep apnea hypopnea syndrome].

Liao LB, Zhai JM, Chen GG, Ma ZE, Yang XB, Zhang JG.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Jun 5;31(11):854-858. doi: 10.13201/j.issn.1001-1781.2017.11.009. Chinese.


Peritumoral overexpression of ZBP-89 is associated with unfavorable disease-free survival rates in patients with hepatocellular carcinoma following hepatectomy.

Wang QS, Chen C, Zhan J, Fang XF, Chen GG, Yang SL, Chen RW, Tong F, Hu JL.

Oncol Lett. 2018 May;15(5):7828-7836. doi: 10.3892/ol.2018.8353. Epub 2018 Mar 26.


Association of PD-L1 and HIF-1α Coexpression with Poor Prognosis in Hepatocellular Carcinoma.

Dai X, Pi G, Yang SL, Chen GG, Liu LP, Dong HH.

Transl Oncol. 2018 Apr;11(2):559-566. doi: 10.1016/j.tranon.2018.02.014. Epub 2018 Mar 8.


CD133 expression and α-fetoprotein levels define novel prognostic subtypes of HBV-associated hepatocellular carcinoma: A long-term follow-up analysis.

Dai XM, Yang SL, Zheng XM, Chen GG, Chen J, Zhang T.

Oncol Lett. 2018 Mar;15(3):2985-2991. doi: 10.3892/ol.2017.7704. Epub 2017 Dec 28.


Crosstalk between prognostic long noncoding RNAs and messenger RNAs as transcriptional hallmarks in gastric cancer.

Zhang J, Yuan Y, Wei Z, Ren J, Hou X, Yang D, Cai S, Chen C, Tan M, Chen GG, Wu K, He Y.

Epigenomics. 2018 Apr 1;10(4):433-443. doi: 10.2217/epi-2017-0136. Epub 2018 Feb 6.


Concomitant high expression of ERα36, GRP78 and GRP94 is associated with aggressive papillary thyroid cancer behavior.

Dai YJ, Qiu YB, Jiang R, Xu M, Liao LY, Chen GG, Liu ZM.

Cell Oncol (Dordr). 2018 Jun;41(3):269-282. doi: 10.1007/s13402-017-0368-y. Epub 2018 Jan 24.


TNF-α induces Drp1-mediated mitochondrial fragmentation during inflammatory cardiomyocyte injury.

Shen YL, Shi YZ, Chen GG, Wang LL, Zheng MZ, Jin HF, Chen YY.

Int J Mol Med. 2018 Apr;41(4):2317-2327. doi: 10.3892/ijmm.2018.3385. Epub 2018 Jan 15.


Global Weak Rigidity of the Gauss-Codazzi-Ricci Equations and Isometric Immersions of Riemannian Manifolds with Lower Regularity.

Chen GG, Li S.

J Geom Anal. 2018;28(3):1957-2007. doi: 10.1007/s12220-017-9893-1. Epub 2017 Aug 18.


Corrigendum to "Peritumoral EpCAM Is an Independent Prognostic Marker after Curative Resection of HBV-Related Hepatocellular Carcinoma".

Dai XM, Huang T, Yang SL, Zheng XM, Chen GG, Zhang T.

Dis Markers. 2017;2017:3765279. doi: 10.1155/2017/3765279. Epub 2017 Sep 20.


Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma.

Sun YF, Guo W, Xu Y, Shi YH, Gong ZJ, Ji Y, Du M, Zhang X, Hu B, Huang A, Chen GG, Lai PBS, Cao Y, Qiu SJ, Zhou J, Yang XR, Fan J.

Clin Cancer Res. 2018 Feb 1;24(3):547-559. doi: 10.1158/1078-0432.CCR-17-1063. Epub 2017 Oct 25.


New insights into sorafenib resistance in hepatocellular carcinoma: Responsible mechanisms and promising strategies.

Niu L, Liu L, Yang S, Ren J, Lai PBS, Chen GG.

Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):564-570. doi: 10.1016/j.bbcan.2017.10.002. Epub 2017 Oct 17. Review.


Concomitant high expression of ERα36, EGFR and HER2 is associated with aggressive behaviors of papillary thyroid carcinomas.

Dai YJ, Qiu YB, Jiang R, Xu M, Zhao L, Chen GG, Liu ZM.

Sci Rep. 2017 Sep 25;7(1):12279. doi: 10.1038/s41598-017-12478-1.


Editorial Special Issue on the Occasion of Prof. Dr. Alf Pühler's 75th birthday.

Alves PM, Becker A, Blöcker H, Chan RL, Chen GG, Fussenegger M, Kondo A, Kourist R, Schwab H, Seo JH, Sensen CW, Sensen M, Scrienc F.

J Biotechnol. 2017 Sep 10;257:1. doi: 10.1016/j.jbiotec.2017.07.013. No abstract available.


Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence.

Lutz PE, Tanti A, Gasecka A, Barnett-Burns S, Kim JJ, Zhou Y, Chen GG, Wakid M, Shaw M, Almeida D, Chay MA, Yang J, Larivière V, M'Boutchou MN, van Kempen LC, Yerko V, Prud'homme J, Davoli MA, Vaillancourt K, Théroux JF, Bramoullé A, Zhang TY, Meaney MJ, Ernst C, Côté D, Mechawar N, Turecki G.

Am J Psychiatry. 2017 Dec 1;174(12):1185-1194. doi: 10.1176/appi.ajp.2017.16111286. Epub 2017 Jul 28.


FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer.

Yang S, Liu Y, Li MY, Ng CSH, Yang SL, Wang S, Zou C, Dong Y, Du J, Long X, Liu LZ, Wan IYP, Mok T, Underwood MJ, Chen GG.

Mol Cancer. 2017 Jul 17;16(1):124. doi: 10.1186/s12943-017-0700-1.


[Effects of Human Acellular Amniotic Membrane on Postsurgical Recovery of Nail Beds].

Xue SL, Chen GG, Lü X, Mei R.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2016 Jul;47(4):533-536. Chinese.


Peritumoral EpCAM Is an Independent Prognostic Marker after Curative Resection of HBV-Related Hepatocellular Carcinoma.

Dai XM, Huang T, Yang SL, Zheng XM, Chen GG, Zhang T.

Dis Markers. 2017;2017:8495326. doi: 10.1155/2017/8495326. Epub 2017 May 10. Erratum in: Dis Markers. 2017;2017:3765279.


Positive Expression of Programmed Death Ligand 1 in Peritumoral Liver Tissue is Associated with Poor Survival after Curative Resection of Hepatocellular Carcinoma.

Dai X, Xue J, Hu J, Yang SL, Chen GG, Lai PBS, Yu C, Zeng C, Fang X, Pan X, Zhang T.

Transl Oncol. 2017 Aug;10(4):511-517. doi: 10.1016/j.tranon.2017.03.009. Epub 2017 May 27.

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