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Items: 1 to 50 of 18687

1.

Ability of preschoolers to achieve maximal exercise and its correlation with oxygen uptake efficiency slope ∼ an observational study by direct cardiopulmonary exercise testing.

Tuan SH, Su HT, Chen YJ, Chen CH, Tsai WJ, Chen GB, Lin KL.

Medicine (Baltimore). 2018 Nov;97(46):e13296. doi: 10.1097/MD.0000000000013296.

PMID:
30431617
2.

Monoacylglycerol Lipase Inactivation by Using URB602 Mitigates Myocardial Damage in a Rat Model of Cardiac Arrest.

Hai K, Chen G, Gou X, Jang H, Gong D, Cheng Y, Gong C, Li X, Liu Y, Li H, Zhang G, Yang L, Ke B, Liu J.

Crit Care Med. 2018 Nov 13. doi: 10.1097/CCM.0000000000003552. [Epub ahead of print]

PMID:
30431495
3.

MicroRNA‑584 directly targets CCND1 and inhibits cell proliferation and invasion in pancreatic cancer.

Chen G, Hu M, Qu X, Wang K, Qu Y.

Mol Med Rep. 2018 Nov 13. doi: 10.3892/mmr.2018.9651. [Epub ahead of print]

PMID:
30431107
4.

DOK7V1 influences the malignant phenotype of lung cancer cells through PI3K/AKT/mTOR and FAK/paxillin signaling pathways.

Zhao H, Chen G, Ye L, Yu H, Li S, Jiang WG.

Int J Oncol. 2018 Nov 5. doi: 10.3892/ijo.2018.4624. [Epub ahead of print]

PMID:
30431081
5.

Ultrastable Luminescent Organic-Inorganic Perovskite Quantum Dots via Surface Engineering: Coordination of Methylammonium Bromide and Covalent Silica Encapsulation.

Zeng FL, Yang M, Qin JL, Teng F, Wang YQ, Chen GX, Wang DW, Peng HS.

ACS Appl Mater Interfaces. 2018 Nov 15. doi: 10.1021/acsami.8b14677. [Epub ahead of print]

PMID:
30430827
6.

Negative pressure pulmonary edema after percutaneous endoscopic interlaminar lumbar discectomy-a case report.

Chen G, Wang XD, Nie HF, Yang ZQ, Chen K, Li ZH, Song YM, Pei FX, Zeng JC.

BMC Musculoskelet Disord. 2018 Nov 14;19(1):401. doi: 10.1186/s12891-018-2306-1.

PMID:
30428864
7.

Effects of Lactococcus lactis subsp. lactis JCM5805 on colonization dynamics of gut microbiota and regulation of immunity in early ontogenetic stages of tilapia.

Xia Y, Cao J, Wang M, Lu M, Chen G, Gao F, Liu Z, Zhang D, Ke X, Yi M.

Fish Shellfish Immunol. 2018 Nov 11. pii: S1050-4648(18)30741-1. doi: 10.1016/j.fsi.2018.11.022. [Epub ahead of print]

PMID:
30428393
8.

Design, synthesis and biological evaluation of imidazo[1,2-a]pyridine analogues or derivatives as anti-helmintic drug.

Zhou S, Chen G, Huang G.

Chem Biol Drug Des. 2018 Nov 14. doi: 10.1111/cbdd.13441. [Epub ahead of print]

PMID:
30427117
9.

LRRC8A potentiates temozolomide sensitivity in glioma cells via activating mitochondria-dependent apoptotic pathway.

Yang C, He L, Chen G, Ning Z, Xia Z.

Hum Cell. 2018 Nov 13. doi: 10.1007/s13577-018-0221-2. [Epub ahead of print]

PMID:
30426452
10.

Echinacoside protects against MPTP/MPP+-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.

Chen C, Xia B, Tang L, Wu W, Tang J, Liang Y, Yang H, Zhang Z, Lu Y, Chen G, Yang Y, Zhao Y.

Metab Brain Dis. 2018 Nov 13. doi: 10.1007/s11011-018-0330-3. [Epub ahead of print]

PMID:
30426321
11.

Preventive agents for neurodegenerative diseases from resin of Dracaena cochinchinensis attenuate LPS-induced microglia over-activation.

Tang Y, Su G, Li N, Li W, Chen G, Chen R, Zhou D, Hou Y.

J Nat Med. 2018 Nov 13. doi: 10.1007/s11418-018-1266-y. [Epub ahead of print]

PMID:
30426288
12.

Antifungal Activity and Action Mechanism of Ginger Oleoresin Against Pestalotiopsis microspora Isolated From Chinese Olive Fruits.

Chen T, Lu J, Kang B, Lin M, Ding L, Zhang L, Chen G, Chen S, Lin H.

Front Microbiol. 2018 Oct 30;9:2583. doi: 10.3389/fmicb.2018.02583. eCollection 2018.

13.

Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.

Cao S, Chen G, Yan L, Li L, Huang X.

Onco Targets Ther. 2018 Oct 24;11:7385-7394. doi: 10.2147/OTT.S177524. eCollection 2018.

14.

Structural Studies of the 3',3'-cGAMP Riboswitch Induced by Cognate and Noncognate Ligands Using Molecular Dynamics Simulation.

Li C, Zhao X, Zhu X, Xie P, Chen G.

Int J Mol Sci. 2018 Nov 9;19(11). pii: E3527. doi: 10.3390/ijms19113527.

15.
16.

Chirality Enabled Liquid Crystalline Physical Gels with High Modulus but Low Driving Voltage.

Ruan H, Chen G, Zhao X, Wang Y, Liao Y, Peng H, Feng CL, Xie X, Smalyukh II.

ACS Appl Mater Interfaces. 2018 Nov 13. doi: 10.1021/acsami.8b14488. [Epub ahead of print]

PMID:
30421604
17.

CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans.

Au V, Li-Leger E, Raymant G, Flibotte S, Chen G, Martin K, Fernando L, Doell C, Rosell FL, Wang S, Edgley ML, Rougvie AE, Hutter H, Moerman DG.

G3 (Bethesda). 2018 Nov 12. pii: g3.200778.2018. doi: 10.1534/g3.118.200778. [Epub ahead of print]

18.

Signal and noise characteristics of a CdTe-based photon counting detector: Cascaded systems analysis and experimental studies.

Ji X, Zhang R, Ge Y, Chen GH, Li K.

Proc SPIE Int Soc Opt Eng. 2017 Feb;10132. pii: 1013207. doi: 10.1117/12.2255063. Epub 2017 Mar 9.

19.

Hepatitis C virus genotype diversity and distribution among methadone maintenance treatment patients in Jiangsu, China.

Lu J, Zhang L, Xu X, Chen Y, Zhou Y, Zhang Z, Fu G, Chen G.

Drug Alcohol Depend. 2018 Nov 3;194:101-106. doi: 10.1016/j.drugalcdep.2018.09.026. [Epub ahead of print]

PMID:
30419403
20.

Rapid and sensitive detection of Amphidinium carterae by loop-mediated isothermal amplification combined with a chromatographic lateral-flow dipstick.

Wang L, Chen GF, Zhang CY, Wang YY, Sun R.

Mol Cell Probes. 2018 Nov 9. pii: S0890-8508(18)30241-X. doi: 10.1016/j.mcp.2018.11.001. [Epub ahead of print]

PMID:
30419277
21.

Intraspectrum Discrimination and Interspectrum Correlation Analysis Deep Network for Multispectral Face Recognition.

Wu F, Jing XY, Dong X, Hu R, Yue D, Wang L, Ji YM, Wang R, Chen G.

IEEE Trans Cybern. 2018 Nov 6. doi: 10.1109/TCYB.2018.2876591. [Epub ahead of print]

PMID:
30418895
22.

Confining Redox Electrolytes in Functionalized Porous Carbon with Improved Energy Density for Supercapacitors.

Yan L, Li D, Yan T, Chen G, Shi L, An Z, Zhang D.

ACS Appl Mater Interfaces. 2018 Nov 12. doi: 10.1021/acsami.8b16642. [Epub ahead of print]

PMID:
30418743
23.

TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro.

Balleza-Tapia H, Crux S, Andrade-Talavera Y, Dolz-Gaiton P, Papadia D, Chen G, Johansson J, Fisahn A.

Elife. 2018 Nov 12;7. pii: e37703. doi: 10.7554/eLife.37703. [Epub ahead of print]

24.

Thiol-ene click reaction-induced fluorescence enhancement by altering the radiative rate for assaying butyrylcholinesterase activity.

Chen G, Feng H, Xi W, Xu J, Pan S, Qian Z.

Analyst. 2018 Nov 12. doi: 10.1039/c8an01808a. [Epub ahead of print]

PMID:
30417195
25.

Detection of reverse triggering in a 55-year-old man under deep sedation and controlled mechanical ventilation.

He X, Luo XY, Chen GQ, Zhou JX.

J Thorac Dis. 2018 Sep;10(9):E682-E685. doi: 10.21037/jtd.2018.08.09. No abstract available.

26.

Analysis of Prestenting on Outcomes of Flexible Ureteroscopy for Upper Urinary Urolithiasis: A Historical Control Study.

Chen H, Chen G, Zhu Y, Yang Z, Xiong C, Pan Y.

Urol Int. 2018 Nov 9:1-6. doi: 10.1159/000494362. [Epub ahead of print]

PMID:
30415258
27.

Serum immunoglobulin G provides early risk prediction in immunoglobulin A nephropathy.

Liu D, You J, Liu Y, Tang X, Tan X, Xia M, Wu L, Chen G, He L, Zhu X, Liu H.

Int Immunopharmacol. 2018 Nov 8;66:13-18. doi: 10.1016/j.intimp.2018.10.044. [Epub ahead of print]

PMID:
30415190
28.

Impaired growth in rural Gambian infants exposed to aflatoxin: a prospective cohort study.

Watson S, Moore SE, Darboe MK, Chen G, Tu YK, Huang YT, Eriksen KG, Bernstein RM, Prentice AM, Wild CP, Xu Y, Routledge MN, Gong YY.

BMC Public Health. 2018 Nov 9;18(1):1247. doi: 10.1186/s12889-018-6164-4.

29.

The Effects of Different Degrees of Procyanidin Polymerization on the Nutrient Absorption and Digestive Enzyme Activity in Mice.

Zhong H, Xue Y, Lu X, Shao Q, Cao Y, Wu Z, Chen G.

Molecules. 2018 Nov 8;23(11). pii: E2916. doi: 10.3390/molecules23112916.

30.

Measurement of the Branching Fraction For the Semileptonic Decay D^{0(+)}→π^{-(0)}μ^{+}ν_{μ} and Test of Lepton Flavor Universality.

Ablikim M, Achasov MN, Ahmed S, Albrecht M, Amoroso A, An FF, An Q, Bai JZ, Bai Y, Bakina O, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Berger N, Bertani M, Bettoni D, Bian JM, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Cakir O, Calcaterra A, Cao GF, Cetin SA, Chai J, Chang JF, Chelkov G, Chen G, Chen HS, Chen JC, Chen ML, Chen PL, Chen SJ, Chen XR, Chen YB, Chu XK, Cibinetto G, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Duan PF, Fang J, Fang SS, Fang Y, Farinelli R, Fava L, Fegan S, Feldbauer F, Felici G, Feng CQ, Fioravanti E, Fritsch M, Fu CD, Gao Q, Gao XL, Gao Y, Gao YG, Gao Z, Garzia I, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu MH, Gu YT, Guo AQ, Guo RP, Guo YP, Haddadi Z, Han S, Hao XQ, Harris FA, He KL, He XQ, Heinsius FH, Held T, Heng YK, Holtmann T, Hou ZL, Hu HM, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huang ZL, Hussain T, Ikegami Andersson W, Ji Q, Ji QP, Ji XB, Ji XL, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Jin Y, Johansson T, Julin A, Kalantar-Nayestanaki N, Kang XL, Kang XS, Kavatsyuk M, Ke BC, Khan T, Khoukaz A, Kiese P, Kliemt R, Koch L, Kolcu OB, Kopf B, Kornicer M, Kuemmel M, Kuessner M, Kuhlmann M, Kupsc A, Kühn W, Lange JS, Lara M, Larin P, Lavezzi L, Leithoff H, Leng C, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li J, Li KJ, Li K, Li K, Li L, Li PL, Li PR, Li QY, Li WD, Li WG, Li XL, Li XN, Li XQ, Li ZB, Liang H, Liang YF, Liang YT, Liao GR, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu FH, Liu F, Liu F, Liu HB, Liu HM, Liu H, Liu H, Liu JB, Liu JP, Liu JY, Liu K, Liu KY, Liu K, Liu LD, Liu PL, Liu Q, Liu SB, Liu X, Liu YB, Liu ZA, Liu Z, Long YF, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo XL, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma T, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Malik QA, Mao YJ, Mao ZP, Marcello S, Meng ZX, Messchendorp JG, Mezzadri G, Min J, Min TJ, Mitchell RE, Mo XH, Mo YJ, Morales Morales C, Muchnoi NY, Muramatsu H, Musiol P, Mustafa A, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Papenbrock M, Patteri P, Pelizaeus M, Pellegrino J, Peng HP, Peters K, Pettersson J, Ping JL, Ping RG, Pitka A, Poling R, Prasad V, Qi HR, Qi M, Qian S, Qiao CF, Qin N, Qin XS, Qin ZH, Qiu JF, Rashid KH, Redmer CF, Richter M, Ripka M, Rolo M, Rong G, Rosner C, Sarantsev A, Savrié M, Schnier C, Schoenning K, Shan W, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Song JJ, Song WM, Song XY, Sosio S, Sowa C, Spataro S, Sun GX, Sun JF, Sun L, Sun SS, Sun XH, Sun YJ, Sun YK, Sun YZ, Sun ZJ, Sun ZT, Tang CJ, Tang GY, Tang X, Tapan I, Tiemens M, Tsednee B, Uman I, Varner GS, Wang B, Wang BL, Wang D, Wang DY, Wang D, Wang K, Wang LL, Wang LS, Wang M, Wang M, Wang P, Wang PL, Wang WP, Wang XF, Wang Y, Wang YD, Wang YF, Wang YQ, Wang Z, Wang ZG, Wang ZY, Wang Z, Weber T, Wei DH, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia Y, Xiao D, Xiao H, Xiao YJ, Xiao ZJ, Xie YG, Xie YH, Xiong XA, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu QN, Xu XP, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang YH, Yang YX, Ye M, Ye MH, Yin JH, You ZY, Yu BX, Yu CX, Yu JS, Yuan CZ, Yuan Y, Yuncu A, Zafar AA, Zeng Y, Zeng Z, Zhang BX, Zhang BY, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang SQ, Zhang XY, Zhang YH, Zhang YT, Zhang Y, Zhang Y, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng YH, Zhong B, Zhou L, Zhou X, Zhou XK, Zhou XR, Zhou XY, Zhou YX, Zhu J, Zhu J, Zhu K, Zhu KJ, Zhu S, Zhu SH, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2018 Oct 26;121(17):171803. doi: 10.1103/PhysRevLett.121.171803.

PMID:
30411926
31.

[Spatial distributions and environmental control of diatom functional groups in sediments of Haixi Lake, Southwest China.]

Wang JY, Chen GJ, Kang WG, Hu K, Chen XL, Wu FH, Zhu QS, Feng Z.

Ying Yong Sheng Tai Xue Bao. 2018 Sep;29(9):3120-3130. doi: 10.13287/j.1001-9332.201809.006. Chinese.

PMID:
30411590
32.

[Spatial distribution of cladoceran assemblages in surface sediments of shallow lakes in Yunnan.]

Zhu QS, Kong LY, Chen L, Wang X, Wang JY, Kang WG, Li R, Liang H, Chen GJ.

Ying Yong Sheng Tai Xue Bao. 2018 Sep;29(9):3111-3119. doi: 10.13287/j.1001-9332.201809.032. Chinese.

PMID:
30411589
33.

Comparative on plant stoichiometry response to agricultural non-point source pollution in different types of ecological ditches.

Wang J, Chen G, Zou G, Song X, Liu F.

Environ Sci Pollut Res Int. 2018 Nov 8. doi: 10.1007/s11356-018-3567-9. [Epub ahead of print]

PMID:
30411294
34.

Overexpression of Peroxiredoxin 6 (PRDX6) Promotes the Aggressive Phenotypes of Esophageal Squamous Cell Carcinoma.

He Y, Xu W, Xiao Y, Pan L, Chen G, Tang Y, Zhou J, Wu J, Zhu W, Zhang S, Cao J.

J Cancer. 2018 Oct 10;9(21):3939-3949. doi: 10.7150/jca.26041. eCollection 2018.

35.

Berberine Combined with Triple Therapy versus Triple Therapy for Helicobacter pylori Eradication: A Meta-Analysis of Randomized Controlled Trials.

Jiang X, Jiang C, Huang C, Chen G, Jiang K, Huang B, Liu F.

Evid Based Complement Alternat Med. 2018 Oct 4;2018:8716910. doi: 10.1155/2018/8716910. eCollection 2018.

36.

Molecular Control of Follicular Helper T cell Development and Differentiation.

Wu H, Deng Y, Zhao M, Zhang J, Zheng M, Chen G, Li L, He Z, Lu Q.

Front Immunol. 2018 Oct 25;9:2470. doi: 10.3389/fimmu.2018.02470. eCollection 2018. Review.

37.

DJ-1 promotes survival of human colon cancer cells under hypoxia by modulating HIF-1α expression through the PI3K-AKT pathway.

Zheng H, Zhou C, Lu X, Liu Q, Liu M, Chen G, Chen W, Wang S, Qiu Y.

Cancer Manag Res. 2018 Oct 16;10:4615-4629. doi: 10.2147/CMAR.S172008. eCollection 2018.

38.

Combined rotational atherectomy and intravascular lithotripsy for the treatment of severely calcified in-stent neoatherosclerosis: A mini-review.

Chen G, Zrenner B, Pyxaras SA.

Cardiovasc Revasc Med. 2018 Oct 27. pii: S1553-8389(18)30446-9. doi: 10.1016/j.carrev.2018.10.007. [Epub ahead of print] Review.

PMID:
30409500
39.

Early life exposure to particulate matter air pollution (PM1, PM2.5 and PM10) and autism in Shanghai, China: A case-control study.

Chen G, Jin Z, Li S, Jin X, Tong S, Liu S, Yang Y, Huang H, Guo Y.

Environ Int. 2018 Oct 30. pii: S0160-4120(18)31324-2. doi: 10.1016/j.envint.2018.10.026. [Epub ahead of print]

PMID:
30409451
40.

Associations of urinary polycyclic aromatic hydrocarbons with age at natural menopause in U.S. women aged 35-65, NHANES 2003-2012.

Huang Y, Guo J, Lv N, Li S, Wu Y, Bai R, Shen J, Chen G, Zhang D.

Environ Pollut. 2018 Dec;243(Pt B):1878-1886. doi: 10.1016/j.envpol.2018.09.109. Epub 2018 Oct 3.

PMID:
30408876
41.

LncRNA NEAT1 promotes the tumorigenesis of colorectal cancer by sponging miR-193a-3p.

Yu HM, Wang C, Yuan Z, Chen GL, Ye T, Yang BW.

Cell Prolif. 2018 Nov 8:e12526. doi: 10.1111/cpr.12526. [Epub ahead of print]

PMID:
30407674
42.

Efficacy and safety of Xiaofeng powder (xiao feng san) in treating urticaria: A protocol for a systematic review and meta-analysis of randomized controlled trials.

Chen G, Zhao J, Chen T, Zhang Z, Huang C, Xu Z, Xu H.

Medicine (Baltimore). 2018 Nov;97(45):e13039. doi: 10.1097/MD.0000000000013039.

43.
44.

Functional Hydrogels With Tunable Structures and Properties for Tissue Engineering Applications.

Li X, Sun Q, Li Q, Kawazoe N, Chen G.

Front Chem. 2018 Oct 22;6:499. doi: 10.3389/fchem.2018.00499. eCollection 2018. Review.

45.

Interaction Between Prediabetes and the ABO Blood Types in Predicting Postsurgical Esophageal Squamous Cell Carcinoma-Specific Mortality: The FIESTA Study.

Fan G, Hu D, Zhang X, Peng F, Lin X, Chen G, Liang B, Zhang H, Xia Y, Zheng X, Jie J, Niu W.

Front Oncol. 2018 Oct 23;8:461. doi: 10.3389/fonc.2018.00461. eCollection 2018.

46.

Uncovering the Changing Gene Expression Profile of Honeybee (Apis mellifera) Worker Larvae Transplanted to Queen Cells.

Yin L, Wang K, Niu L, Zhang H, Chen Y, Ji T, Chen G.

Front Genet. 2018 Oct 24;9:416. doi: 10.3389/fgene.2018.00416. eCollection 2018.

47.

Influence of Audiovisual Training on Horizontal Sound Localization and Its Related ERP Response.

Cai Y, Chen G, Zhong X, Yu G, Mo H, Jiang J, Chen X, Zhao F, Zheng Y.

Front Hum Neurosci. 2018 Oct 23;12:423. doi: 10.3389/fnhum.2018.00423. eCollection 2018.

48.

Synthesis of Polyaromatic Rings: Rh(III)-Catalyzed [5 + 1] Annulation of Enaminones with Vinyl Esters through C-H Bond Functionalization.

Liang G, Rong J, Sun W, Chen G, Jiang Y, Loh TP.

Org Lett. 2018 Nov 7. doi: 10.1021/acs.orglett.8b03284. [Epub ahead of print]

PMID:
30403359
49.

Long non-coding RNA expression profile in permanent atrial fibrillation patients with rheumatic heart disease.

Mei B, Liu H, Yang S, Liang MY, Yue Y, Huang SQ, Hou J, Chen GX, Wu ZK.

Eur Rev Med Pharmacol Sci. 2018 Oct;22(20):6940-6947. doi: 10.26355/eurrev_201810_16165.

PMID:
30402860
50.

Speed-adaptive control of functional electrical stimulation for dropfoot correction.

Chen G, Ma L, Song R, Li L, Wang X, Tong K.

J Neuroeng Rehabil. 2018 Nov 6;15(1):98. doi: 10.1186/s12984-018-0448-x.

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