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From Deep Learning Towards Finding Skin Lesion Biomarkers.

Li X, Wu J, Chen EZ, Jiang H.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:2797-2800. doi: 10.1109/EMBC.2019.8857334.


Skin Lesion Segmentation with C-UNet.

Wu J, Chen EZ, Rong R, Li X, Xu D, Jiang H.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:2785-2788. doi: 10.1109/EMBC.2019.8857773.


Paclitaxel alleviated sepsis-induced acute lung injury by activating MUC1 and suppressing TLR-4/NF-κB pathway.

Wang YM, Ji R, Chen WW, Huang SW, Zheng YJ, Yang ZT, Qu HP, Chen H, Mao EQ, Chen Y, Chen EZ.

Drug Des Devel Ther. 2019 Sep 24;13:3391-3404. doi: 10.2147/DDDT.S222296. eCollection 2019.


Clinical characteristics of 5375 cases of acute pancreatitis from a single Chinese center, 1996-2015.

Huang SW, Mao EQ, Wang HS, Zhao B, Chen Y, Qu HP, Chen EZ.

Chin Med J (Engl). 2019 May 20;132(10):1233-1236. doi: 10.1097/CM9.0000000000000208. No abstract available.


DC-SIGN Expression in Intestinal Epithelial Cells Regulates Sepsis-Associated Acute Intestinal Injury Via Activating ERK1/2-NF-κB/P65 Signaling.

Chen W, Ma L, Li R, Huang S, Xie R, Chen Y, Zhao B, Fei J, Qu H, Chen H, Mao E, Chen EZ.

Shock. 2019 Oct;52(4):434-442. doi: 10.1097/SHK.0000000000001277.


Intravenous Vitamin C attenuates hemorrhagic shock-related renal injury through the induction of SIRT1 in rats.

Qi MZ, Yao Y, Xie RL, Sun SL, Sun WW, Wang JL, Chen Y, Zhao B, Chen EZ, Mao EQ.

Biochem Biophys Res Commun. 2018 Jun 22;501(2):358-364. doi: 10.1016/j.bbrc.2018.04.111.


Mycophenolate Mofetil Protects Septic Mice via the Dual Inhibition of Inflammatory Cytokines and PD-1.

Huang SW, Chen H, Lu ML, Wang JL, Xie RL, Zhao B, Chen Y, Xu ZW, Fei J, Mao EQ, Chen EZ.

Inflammation. 2018 Jun;41(3):1008-1020. doi: 10.1007/s10753-018-0754-2.


A role for bacterial urease in gut dysbiosis and Crohn's disease.

Ni J, Shen TD, Chen EZ, Bittinger K, Bailey A, Roggiani M, Sirota-Madi A, Friedman ES, Chau L, Lin A, Nissim I, Scott J, Lauder A, Hoffmann C, Rivas G, Albenberg L, Baldassano RN, Braun J, Xavier RJ, Clish CB, Yudkoff M, Li H, Goulian M, Bushman FD, Lewis JD, Wu GD.

Sci Transl Med. 2017 Nov 15;9(416). pii: eaah6888. doi: 10.1126/scitranslmed.aah6888.


A Model-Based Approach For Species Abundance Quantification Based On Shotgun Metagenomic Data.

Chen EZ, Bushman FD, Li H.

Stat Biosci. 2017 Jun;9(1):13-27. doi: 10.1007/s12561-016-9148-x. Epub 2016 May 16.


Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn's Disease.

Lewis JD, Chen EZ, Baldassano RN, Otley AR, Griffiths AM, Lee D, Bittinger K, Bailey A, Friedman ES, Hoffmann C, Albenberg L, Sinha R, Compher C, Gilroy E, Nessel L, Grant A, Chehoud C, Li H, Wu GD, Bushman FD.

Cell Host Microbe. 2017 Aug 9;22(2):247. doi: 10.1016/j.chom.2017.07.011. No abstract available.


Biliary tract external drainage protects against multiple organs injuries of severe acute pancreatitis rats via heme oxygenase-1 upregulation.

Wang JL, Chen Y, Song XQ, Lu ML, Zhao B, Ma L, Chen EZ, Mao EQ.

Pancreatology. 2017 Mar - Apr;17(2):219-227. doi: 10.1016/j.pan.2017.01.012. Epub 2017 Feb 1.


Does training improve diagnostic accuracy and inter-rater agreement in applying the Berlin radiographic definition of acute respiratory distress syndrome? A multicenter prospective study.

Peng JM, Qian CY, Yu XY, Zhao MY, Li SS, Ma XC, Kang Y, Zhou FC, He ZY, Qin TH, Yin YJ, Jiang L, Hu ZJ, Sun RH, Lin JD, Li T, Wu DW, An YZ, Ai YH, Zhou LH, Cao XY, Zhang XJ, Sun RQ, Chen EZ, Du B; China Critical Care Clinical Trial Group (CCCCTG).

Crit Care. 2017 Jan 20;21(1):12. doi: 10.1186/s13054-017-1606-4.


Value of Kidney Disease Improving Global Outcomes Urine Output Criteria in Critically Ill Patients: A Secondary Analysis of a Multicenter Prospective Cohort Study.

Qin JP, Yu XY, Qian CY, Li SS, Qin TH, Chen EZ, Lin JD, Ai YH, Wu DW, Liu DX, Sun RH, Hu ZJ, Cao XY, Zhou FC, He ZY, Zhou LH, An YZ, Kang Y, Ma XC, Zhao MY, Jiang L, Xu Y, Du B; China Critical Care Clinical Trial Group (CCCCTG).

Chin Med J (Engl). 2016 Sep 5;129(17):2050-7. doi: 10.4103/0366-6999.189059.


Vitamin C Attenuates Hemorrhagic Shock-induced Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing Nonintegrin Expression in Tubular Epithelial Cells and Renal Injury in Rats.

Ma L, Fei J, Chen Y, Zhao B, Yang ZT, Wang L, Sheng HQ, Chen EZ, Mao EQ.

Chin Med J (Engl). 2016 Jul 20;129(14):1731-6. doi: 10.4103/0366-6999.185868.


A Cost-Effectiveness Analysis of Clopidogrel for Patients with Non-ST-Segment Elevation Acute Coronary Syndrome in China.

Cui M, Tu CC, Chen EZ, Wang XL, Tan SC, Chen C.

Adv Ther. 2016 Sep;33(9):1600-11. doi: 10.1007/s12325-016-0375-9. Epub 2016 Jul 11.


Prospective observational study to compare oral topical metronidazole versus 0.2% chlorhexidine gluconate to prevent nosocomial pneumonia.

Chen Y, Mao EQ, Yang YJ, Zhao SY, Zhu C, Wang XF, Jing F, Sheng HQ, Yang ZT, Chen EZ.

Am J Infect Control. 2016 Oct 1;44(10):1116-1122. doi: 10.1016/j.ajic.2016.03.054. Epub 2016 Jun 14.


The revised Atlanta criteria 2012 altered the classification, severity assessment and management of acute pancreatitis.

Huang J, Qu HP, Zheng YF, Song XW, Li L, Xu ZW, Mao EQ, Chen EZ.

Hepatobiliary Pancreat Dis Int. 2016 Jun;15(3):310-5.


Effect of S100A12 and soluble receptor for advanced glycation end products on the occurrence of severe acute pancreatitis.

Zhao B, Chen Y, Sun WW, Chen WW, Ma L, Yang ZT, Huang J, Chen EZ, Fei J, Mao EQ.

J Dig Dis. 2016 Jul;17(7):475-82. doi: 10.1111/1751-2980.12364.


A two-part mixed-effects model for analyzing longitudinal microbiome compositional data.

Chen EZ, Li H.

Bioinformatics. 2016 Sep 1;32(17):2611-7. doi: 10.1093/bioinformatics/btw308. Epub 2016 May 14.


Pre-Treatment Serum C-Reactive Protein Level Is An Independent Risk Factor for Development of Nephrotoxicity in Patients Receiving High-Dose Vancomycin.

He J, Mao EQ, Jing F, Jiang HT, Yang WH, Chen EZ.

Pharmacology. 2016;97(5-6):294-300. doi: 10.1159/000443895. Epub 2016 Feb 27.


The pharmacokinetics of vancomycin in patients with severe acute pancreatitis.

He J, Mao EQ, Feng J, Jiang HT, Yang WH, Chen EZ.

Eur J Clin Pharmacol. 2016 Jun;72(6):697-702. doi: 10.1007/s00228-016-2018-0. Epub 2016 Feb 23.


Biliary tract external drainage protects against intestinal barrier injury in hemorrhagic shock rats.

Wang L, Zhao B, Chen Y, Ma L, Chen EZ, Mao EQ.

World J Gastroenterol. 2015 Dec 7;21(45):12800-13. doi: 10.3748/wjg.v21.i45.12800.


Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn's Disease.

Lewis JD, Chen EZ, Baldassano RN, Otley AR, Griffiths AM, Lee D, Bittinger K, Bailey A, Friedman ES, Hoffmann C, Albenberg L, Sinha R, Compher C, Gilroy E, Nessel L, Grant A, Chehoud C, Li H, Wu GD, Bushman FD.

Cell Host Microbe. 2015 Oct 14;18(4):489-500. doi: 10.1016/j.chom.2015.09.008. Erratum in: Cell Host Microbe. 2017 Aug 9;22(2):247.


EUS-guided liver biopsy provides diagnostic samples comparable with those via the percutaneous or transjugular route.

Pineda JJ, Diehl DL, Miao CL, Johal AS, Khara HS, Bhanushali A, Chen EZ.

Gastrointest Endosc. 2016 Feb;83(2):360-5. doi: 10.1016/j.gie.2015.08.025. Epub 2015 Aug 22.


Inflammation and Edema in the Lung and Kidney of Hemorrhagic Shock Rats Are Alleviated by Biliary Tract External Drainage via the Heme Oxygenase-1 Pathway.

Wang L, Zhao B, Chen Y, Ma L, Chen EZ, Mao EQ.

Inflammation. 2015 Dec;38(6):2242-51. doi: 10.1007/s10753-015-0208-z.


Biliary tract external drainage increases the expression levels of heme oxygenase-1 in rat livers.

Wang L, Zhao B, Chen Y, Ma L, Chen EZ, Mao EQ.

Eur J Med Res. 2015 Jul 22;20:61. doi: 10.1186/s40001-015-0152-2.


Endoscopic ultrasound-guided liver biopsy: a multicenter experience.

Diehl DL, Johal AS, Khara HS, Stavropoulos SN, Al-Haddad M, Ramesh J, Varadarajulu S, Aslanian H, Gordon SR, Shieh FK, Pineda-Bonilla JJ, Dunkelberger T, Gondim DD, Chen EZ.

Endosc Int Open. 2015 Jun;3(3):E210-5. doi: 10.1055/s-0034-1391412. Epub 2015 Feb 27.


Biliary tract external drainage alleviates kidney injury in shock.

Wang L, Zhao B, Chen Y, Ma L, Chen EZ, Mao EQ.

J Surg Res. 2015 Dec;199(2):564-71. doi: 10.1016/j.jss.2015.05.025. Epub 2015 May 21.


Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma.

Jacobson BA, Chen EZ, Tang S, Belgum HS, McCauley JA, Evenson KA, Etchison RG, Jay-Dixon J, Patel MR, Raza A, Saluja AK, D'Cunha J, Kratzke RA.

Genes Cancer. 2015 Mar;6(3-4):144-52.


Comparative Effectiveness of Nutritional and Biological Therapy in North American Children with Active Crohn's Disease.

Lee D, Baldassano RN, Otley AR, Albenberg L, Griffiths AM, Compher C, Chen EZ, Li H, Gilroy E, Nessel L, Grant A, Chehoud C, Bushman FD, Wu GD, Lewis JD.

Inflamm Bowel Dis. 2015 Aug;21(8):1786-93. doi: 10.1097/MIB.0000000000000426.


Genome wide nucleosome mapping for HSV-1 shows nucleosomes are deposited at preferred positions during lytic infection.

Oh J, Sanders IF, Chen EZ, Li H, Tobias JW, Isett RB, Penubarthi S, Sun H, Baldwin DA, Fraser NW.

PLoS One. 2015 Feb 24;10(2):e0117471. doi: 10.1371/journal.pone.0117471. eCollection 2015.


Association between Glu504Lys polymorphism of ALDH2 gene and cancer risk: a meta-analysis.

Cai Q, Wu J, Cai Q, Chen EZ, Jiang ZY.

PLoS One. 2015 Feb 13;10(2):e0117173. doi: 10.1371/journal.pone.0117173. eCollection 2015.


Comparative metabolomics in vegans and omnivores reveal constraints on diet-dependent gut microbiota metabolite production.

Wu GD, Compher C, Chen EZ, Smith SA, Shah RD, Bittinger K, Chehoud C, Albenberg LG, Nessel L, Gilroy E, Star J, Weljie AM, Flint HJ, Metz DC, Bennett MJ, Li H, Bushman FD, Lewis JD.

Gut. 2016 Jan;65(1):63-72. doi: 10.1136/gutjnl-2014-308209. Epub 2014 Nov 26.


Vitamin C treatment attenuates hemorrhagic shock related multi-organ injuries through the induction of heme oxygenase-1.

Zhao B, Fei J, Chen Y, Ying YL, Ma L, Song XQ, Huang J, Chen EZ, Mao EQ.

BMC Complement Altern Med. 2014 Nov 12;14:442. doi: 10.1186/1472-6882-14-442.


Relationship between CYP7A1 -204A>C polymorphism with gallbladder stone disease and serum lipid levels: a meta-analysis.

Cai Q, Wang ZQ, Cai Q, Li C, Chen EZ, Jiang ZY.

Lipids Health Dis. 2014 Aug 8;13:126. doi: 10.1186/1476-511X-13-126.


Pharmacological preconditioning with vitamin C attenuates intestinal injury via the induction of heme oxygenase-1 after hemorrhagic shock in rats.

Zhao B, Fei J, Chen Y, Ying YL, Ma L, Song XQ, Wang L, Chen EZ, Mao EQ.

PLoS One. 2014 Jun 13;9(6):e99134. doi: 10.1371/journal.pone.0099134. eCollection 2014.


Epidemiology, species distribution and outcome of nosocomial Candida spp. bloodstream infection in Shanghai.

Yang ZT, Wu L, Liu XY, Zhou M, Li J, Wu JY, Cai Y, Mao EQ, Chen EZ, Lortholary O.

BMC Infect Dis. 2014 May 6;14:241. doi: 10.1186/1471-2334-14-241.


'All singing, all dancing': staff views on the integration of family planning and genitourinary medicine in Lothian, UK.

Higgins M, Chen EZ, Gebbie AE, Fernando I, Milne D, Cochrane R.

J Fam Plann Reprod Health Care. 2014 Oct;40(4):254-60. doi: 10.1136/jfprhc-2013-100590. Epub 2014 May 20.


Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells.

Chen EZ, Jacobson BA, Patel MR, Okon AM, Li S, Xiong K, Vaidya AJ, Bitterman PB, Wagner CR, Kratzke RA.

Invest New Drugs. 2014 Aug;32(4):598-603. doi: 10.1007/s10637-014-0076-7. Epub 2014 Apr 9.


Association of three common single nucleotide polymorphisms of ATP binding cassette G8 gene with gallstone disease: a meta-analysis.

Jiang ZY, Cai Q, Chen EZ.

PLoS One. 2014 Jan 30;9(1):e87200. doi: 10.1371/journal.pone.0087200. eCollection 2014.


Risk of bladder cancer in renal transplant recipients: a meta-analysis.

Yan L, Chen P, Chen EZ, Gu A, Jiang ZY.

Br J Cancer. 2014 Apr 2;110(7):1871-7. doi: 10.1038/bjc.2014.44. Epub 2014 Feb 4.


Prevalence, risk factors, clinical course, and outcome of acute kidney injury in Chinese intensive care units: a prospective cohort study.

Wen Y, Jiang L, Xu Y, Qian CY, Li SS, Qin TH, Chen EZ, Lin JD, Ai YH, Wu DW, Wang YS, Sun RH, Hu ZJ, Cao XY, Zhou FC, He ZY, Zhou LH, An YZ, Kang Y, Ma XC, Yu XY, Zhao MY, Xi XM, DU B; China Critical Care Clinical Trial Group (CCCCTG).

Chin Med J (Engl). 2013 Dec;126(23):4409-16.


A randomized controlled study on the effects of bisoprolol and atenolol on sympathetic nervous activity and central aortic pressure in patients with essential hypertension.

Zhou WJ, Wang RY, Li Y, Chen DR, Chen EZ, Zhu DL, Gao PJ.

PLoS One. 2013 Sep 10;8(9):e72102. doi: 10.1371/journal.pone.0072102. eCollection 2013.


Clinical features and outcomes of patients with severe acute pancreatitis complicated with gangrenous cholecystitis.

Chen EZ, Huang J, Xu ZW, Fei J, Mao EQ, Zhang SD.

Hepatobiliary Pancreat Dis Int. 2013 Jun;12(3):317-23.


Sources of multidrug-resistant Acinetobacter baumannii and its role in respiratory tract colonization and nosocomial pneumonia in intensive care unit patients.

Huang J, Chen EZ, Qu HP, Mao EQ, Zhu ZG, Ni YX, Han LZ, Tang YQ.

Chin Med J (Engl). 2013;126(10):1826-31.


Fluorescence endoscopy of cathepsin activity discriminates dysplasia from colitis.

Gounaris E, Martin J, Ishihara Y, Khan MW, Lee G, Sinh P, Chen EZ, Angarone M, Weissleder R, Khazaie K, Barrett TA.

Inflamm Bowel Dis. 2013 Jun;19(7):1339-45. doi: 10.1097/MIB.0b013e318281f3f8.


Genome-wide roles of Foxa2 in directing liver specification.

Xu C, Lu X, Chen EZ, He Z, Uyunbilig B, Li G, Ma Y, Hui L, Xie B, Gao Y, Ding X, Hu Y, Hu P, Han JD, Wang X.

J Mol Cell Biol. 2012 Dec;4(6):420-2. doi: 10.1093/jmcb/mjs037. Epub 2012 Jun 28. No abstract available.


A Novel YY1-miR-1 regulatory circuit in skeletal myogenesis revealed by genome-wide prediction of YY1-miRNA network.

Lu L, Zhou L, Chen EZ, Sun K, Jiang P, Wang L, Su X, Sun H, Wang H.

PLoS One. 2012;7(2):e27596. doi: 10.1371/journal.pone.0027596. Epub 2012 Feb 1.


Nonhematopoietically derived DNA is shorter than hematopoietically derived DNA in plasma: a transplantation model.

Zheng YW, Chan KC, Sun H, Jiang P, Su X, Chen EZ, Lun FM, Hung EC, Lee V, Wong J, Lai PB, Li CK, Chiu RW, Lo YM.

Clin Chem. 2012 Mar;58(3):549-58. doi: 10.1373/clinchem.2011.169318. Epub 2011 Nov 3.


SFRS7-mediated splicing of tau exon 10 is directly regulated by STOX1A in glial cells.

van Abel D, Hölzel DR, Jain S, Lun FM, Zheng YW, Chen EZ, Sun H, Chiu RW, Lo YM, van Dijk M, Oudejans CB.

PLoS One. 2011;6(7):e21994. doi: 10.1371/journal.pone.0021994. Epub 2011 Jul 6.

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