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Molecular heterogeneity unravelled by single-cell transcriptomics in patients with essential thrombocythaemia.

Hsu CC, Chen YJ, Huang CE, Wu YY, Wang MC, Pei SN, Liao CK, Lu CH, Chen PT, Tsou HY, Li CP, Chuang WH, Chuang CK, Yang CY, Lai YH, Lin YH, Chen CC.

Br J Haematol. 2019 Oct 14. doi: 10.1111/bjh.16225. [Epub ahead of print]


Remarkable cell recovery from cerebral ischemia in rats using an adaptive escalator-based rehabilitation mechanism.

Chen CC, Wang YL, Chang CP.

PLoS One. 2019 Oct 11;14(10):e0223820. doi: 10.1371/journal.pone.0223820. eCollection 2019.


Additive Manufacturing of Nerve Decellularized Extracellular Matrix-Contained Polyurethane Conduits for Peripheral Nerve Regeneration.

Chen YW, Chen CC, Ng HY, Lou CW, Chen YS, Shie MY.

Polymers (Basel). 2019 Oct 4;11(10). pii: E1612. doi: 10.3390/polym11101612.


The medial sural artery perforator pedicled propeller flap for coverage of middle-third leg defects.

Tee R, Jeng SF, Chen CC, Shih HS.

J Plast Reconstr Aesthet Surg. 2019 Sep 7. pii: S1748-6815(19)30378-X. doi: 10.1016/j.bjps.2019.08.006. [Epub ahead of print]


An unusual cause of left lower quadrant abdominal pain.

Chen CC, Cheng CJ, Kuo LJ.

Gastroenterology. 2019 Sep 24. pii: S0016-5085(19)41356-5. doi: 10.1053/j.gastro.2019.09.018. [Epub ahead of print] No abstract available.


Long-term changes of gut microbiota, antibiotic resistance, and metabolic parameters after Helicobacter pylori eradication: a multicentre, open-label, randomised trial.

Liou JM, Chen CC, Chang CM, Fang YJ, Bair MJ, Chen PY, Chang CY, Hsu YC, Chen MJ, Chen CC, Lee JY, Yang TH, Luo JC, Chen CY, Hsu WF, Chen YN, Wu JY, Lin JT, Lu TP, Chuang EY, El-Omar EM, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

Lancet Infect Dis. 2019 Oct;19(10):1109-1120. doi: 10.1016/S1473-3099(19)30272-5.


Association of rs2651899 Polymorphism in the Positive Regulatory Domain 16 and Common Migraine Subtypes: A Meta-Analysis.

Lee HH, Chen CC, Ong JR, Lin YF, Lee FP, Hu CJ, Wang YH.

Headache. 2019 Sep 26. doi: 10.1111/head.13670. [Epub ahead of print]


Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS.

Wang LY, Huang CS, Chen YH, Chen CC, Chen CC, Chuang CH.

Molecules. 2019 Sep 12;24(18). pii: E3317. doi: 10.3390/molecules24183317.


Threshold Effects of PM2.5 Exposure on Particle-Related Mortality in China.

Tran BL, Chang CC, Hsu CS, Chen CC, Tseng WC, Hsu SH.

Int J Environ Res Public Health. 2019 Sep 22;16(19). pii: E3549. doi: 10.3390/ijerph16193549.


Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma.

Chahal KK, Li J, Kufareva I, Parle M, Durden DL, Wechsler-Reya RJ, Chen CC, Abagyan R.

PLoS One. 2019 Sep 20;14(9):e0214901. doi: 10.1371/journal.pone.0214901. eCollection 2019.


Risk of major autoimmune diseases in female breast cancer patients: A nationwide, population-based cohort study.

Chen HH, Lin CH, Chen DY, Chao WC, Chen YH, Hung WT, Chou YY, Wu YD, Chen CC.

PLoS One. 2019 Sep 19;14(9):e0222860. doi: 10.1371/journal.pone.0222860. eCollection 2019.


α-Ketoglutarate links p53 to cell fate during tumour suppression.

Morris JP 4th, Yashinskie JJ, Koche R, Chandwani R, Tian S, Chen CC, Baslan T, Marinkovic ZS, Sánchez-Rivera FJ, Leach SD, Carmona-Fontaine C, Thompson CB, Finley LWS, Lowe SW.

Nature. 2019 Sep;573(7775):595-599. doi: 10.1038/s41586-019-1577-5. Epub 2019 Sep 18.


Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.

Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, Weil AG, Ursini-Siegel J, De Carvalho DD, Dirks PB, Lewis PW, Salomoni P, Lupien M, Arrowsmith C, Lasko PF, Garcia BA, Kleinman CL, Jabado N, Mack SC.

Cancer Cell. 2019 Sep 16;36(3):338-339. doi: 10.1016/j.ccell.2019.08.012. No abstract available.


OutbreakFinder: a visualization tool for rapid detection of bacterial strain clusters based on optimized multidimensional scaling.

Tsai MH, Liu YY, Chen CC.

PeerJ. 2019 Aug 28;7:e7600. doi: 10.7717/peerj.7600. eCollection 2019.


Development and Sensory Experience Dependent Regulation of Microglia in Barrel Cortex.

Kalambogias J, Chen CC, Khan S, Son T, Wercberger R, Headlam C, Lin C, Brumberg JC.

J Comp Neurol. 2019 Sep 9. doi: 10.1002/cne.24771. [Epub ahead of print]


Subthalamic nucleus oscillations correlate with vulnerability to freezing of gait in patients with Parkinson's disease.

Chen CC, Yeh CH, Chan HL, Chang YJ, Tu PH, Yeh CH, Lu CS, Fischer P, Tinkhauser G, Tan H, Brown P.

Neurobiol Dis. 2019 Sep 5;132:104605. doi: 10.1016/j.nbd.2019.104605. [Epub ahead of print]


Stability and Quality of Anthocyanin in Purple Sweet Potato Extracts.

Chen CC, Lin C, Chen MH, Chiang PY.

Foods. 2019 Sep 6;8(9). pii: E393. doi: 10.3390/foods8090393.


Alcohol Consumption and Risk of Chronic Kidney Disease: A Nationwide Observational Cohort Study.

Lai YJ, Chen YY, Lin YK, Chen CC, Yen YF, Deng CY.

Nutrients. 2019 Sep 6;11(9). pii: E2121. doi: 10.3390/nu11092121.


Induction of Autophagic Death of Human Hepatocellular Carcinoma Cells by Armillaridin from Armillaria mellea.

Leu YS, Chen YJ, Chen CC, Huang HL.

Am J Chin Med. 2019;47(6):1365-1380. doi: 10.1142/S0192415X19500708. Epub 2019 Sep 5.


Application of the deep learning for the prediction of rainfall in Southern Taiwan.

Yen MH, Liu DW, Hsin YC, Lin CE, Chen CC.

Sci Rep. 2019 Sep 4;9(1):12774. doi: 10.1038/s41598-019-49242-6.


Efficacy and Safety of Ablative Resurfacing With A High-Energy 1,064 Nd-YAG Picosecond-domain Laser for the Treatment of Facial Acne Scars in Asians.

Dai YX, Chuang YY, Chen PY, Chen CC.

Lasers Surg Med. 2019 Sep 4. doi: 10.1002/lsm.23151. [Epub ahead of print]


Assessment of the intramolecular magnetic interactions in the highly saddled iron(iii) porphyrin π-radical cations: the change from planar to saddle conformations.

Chen CC, Wu YW, Nakamura M, Cheng RJ, Tseng TH, Chen PP.

Dalton Trans. 2019 Sep 17;48(36):13820-13833. doi: 10.1039/c9dt02714a.


A novel DNA repair inhibitor, diallyl disulfide (DADS), impairs DNA resection during DNA double-strand break repair by reducing Sae2 and Exo1 levels.

Kuo CH, Leu YL, Wang TH, Tseng WC, Feng CH, Wang SH, Chen CC.

DNA Repair (Amst). 2019 Oct;82:102690. doi: 10.1016/j.dnarep.2019.102690. Epub 2019 Aug 24.


Distribution of Carnivore protoparvovirus 1 in free-living leopard cats (Prionailurus bengalensis chinensis) and its association with domestic carnivores in Taiwan.

Chen CC, Chang AM, Wada T, Chen MT, Tu YS.

PLoS One. 2019 Sep 3;14(9):e0221990. doi: 10.1371/journal.pone.0221990. eCollection 2019.


Metabolic targeting of HIF-1α potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer.

Wei TT, Lin YT, Tang SP, Luo CK, Tsai CT, Shun CT, Chen CC.

Oncogene. 2019 Sep 2. doi: 10.1038/s41388-019-0999-8. [Epub ahead of print]


Crystal structure of TchmY from Actinoplanes teichomyceticus.

Yang Z, Zhang L, Yu X, Wu S, Yang Y, Hu Y, Li Q, Shang N, Guo RT, Chen CC, Dai L, Liu W.

Acta Crystallogr F Struct Biol Commun. 2019 Sep 1;75(Pt 9):570-575. doi: 10.1107/S2053230X19010914. Epub 2019 Aug 28.


Receipt of brachytherapy is an independent predictor of survival in glioblastoma in the Surveillance, Epidemiology, and End Results database.

Bartek J Jr, Alattar AA, Dhawan S, Ma J, Koga T, Nakaji P, Dusenbery KE, Chen CC.

J Neurooncol. 2019 Oct;145(1):75-83. doi: 10.1007/s11060-019-03268-y. Epub 2019 Aug 30.


C-Reactive Protein Gene Variants and Their Serum Levels in Early Adult-onset Type 2 Diabetes Mellitus.

Huang YC, Chen CC, Wang TY, Nguyen HTT, Chen YH, Wu CM, Chang YW, Liao WL, Tsai FJ.

In Vivo. 2019 Sep-Oct;33(5):1685-1690. doi: 10.21873/invivo.11656.


Breast Tumor Detection and Classification Using Intravoxel Incoherent Motion Hyperspectral Imaging Techniques.

Chan SW, Chang YC, Huang PW, Ouyang YC, Chang YT, Chang RF, Chai JW, Chen CC, Chen HM, Chang CI, Lin CY.

Biomed Res Int. 2019 Jul 28;2019:3843295. doi: 10.1155/2019/3843295. eCollection 2019.


Ambient air pollution is associated with pediatric pneumonia: a time-stratified case-crossover study in an urban area.

Cheng CY, Cheng SY, Chen CC, Pan HY, Wu KH, Cheng FJ.

Environ Health. 2019 Aug 28;18(1):77. doi: 10.1186/s12940-019-0520-4.


Positive Effects of Ger-Gen-Chyn-Lian-Tang on Cholestatic Liver Fibrosis in Bile Duct Ligation-Challenged Mice.

Chang ZY, Chen CC, Liu HM, Yeh YC, Lin TY, Lee TY, Huang TH.

Int J Mol Sci. 2019 Aug 26;20(17). pii: E4181. doi: 10.3390/ijms20174181.


Correction: Huang, H.-M., et al. Effects of Sapindus mukorossi Seed Oil on Skin Wound Healing: In Vivo and In Vitro Testing. Int. J. Mol. Sci. 2019, 20, 2579.

Chen CC, Nien CJ, Chen LG, Huang KY, Chang WJ, Huang HM.

Int J Mol Sci. 2019 Aug 26;20(17). pii: E4178. doi: 10.3390/ijms20174178.


High levels of EGFR prevent sulforaphane-induced reactive oxygen species-mediated apoptosis in non-small-cell lung cancer cells.

Wang TH, Chen CC, Huang KY, Shih YM, Chen CY.

Phytomedicine. 2019 Apr 13;64:152926. doi: 10.1016/j.phymed.2019.152926. [Epub ahead of print]


fMRI indicates cortical activation through TRPV1 modulation during acute gouty attacks.

Chen CC, Chang C, Hsu YH, Peng YJ, Lee HS, Huang GS.

Sci Rep. 2019 Aug 26;9(1):12348. doi: 10.1038/s41598-019-48656-6.


The Prognosis of Blunt Bowel and Mesenteric Injury-the Pitfall in the Contemporary Image Survey.

Liao CH, Hsieh FJ, Chen CC, Cheng CT, Ooyang CH, Hsieh CH, Yang SJ, Fu CY.

J Clin Med. 2019 Aug 24;8(9). pii: E1300. doi: 10.3390/jcm8091300.


Identification and medical utilization of newly diagnosed panic disorder: A Nationwide case-control study.

Chang HM, Pan CH, Chen PH, Chen YL, Su SS, Tsai SY, Chen CC, Kuo CJ.

J Psychosom Res. 2019 Oct;125:109815. doi: 10.1016/j.jpsychores.2019.109815. Epub 2019 Aug 20.


Evidence for a strain-tuned topological phase transition in ZrTe5.

Mutch J, Chen WC, Went P, Qian T, Wilson IZ, Andreev A, Chen CC, Chu JH.

Sci Adv. 2019 Aug 9;5(8):eaav9771. doi: 10.1126/sciadv.aav9771. eCollection 2019 Aug.


Prior Antiplatelet Therapy, Excluding Phosphodiesterase Inhibitor Is Associated with Poor Outcome in Patients with Spontaneous Intracerebral Haemorrhage.

Liu ZH, Liu CH, Tu PH, Yip PK, Chen CC, Wang YC, Chen NY, Lin YS.

Transl Stroke Res. 2019 Aug 24. doi: 10.1007/s12975-019-00722-x. [Epub ahead of print]


Incidence, risk factors and impact on virological response of anemia in chronic genotype 2 hepatitis C receiving sofosbuvir plus ribavirin.

Chen CC, Tung SY, Wei KL, Shen CH, Chang TS, Chen WM, Xu HW, Yen CW, Chen YH, Lu SN, Hung CH.

J Formos Med Assoc. 2019 Aug 21. pii: S0929-6646(19)30413-9. doi: 10.1016/j.jfma.2019.07.028. [Epub ahead of print]


Epidemiologic features of shigellosis and associated climatic factors in Taiwan.

Chen CC, Lin CY, Chen KT.

Medicine (Baltimore). 2019 Aug;98(34):e16928. doi: 10.1097/MD.0000000000016928.


Relationship between fine particulate air pollution exposure and human adult life expectancy in Taiwan.

Chen CC, Chen PS, Yang CY.

J Toxicol Environ Health A. 2019;82(14):826-832. doi: 10.1080/15287394.2019.1658386. Epub 2019 Aug 22.


Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling.

Altman MC, Lai Y, Nolin JD, Long S, Chen CC, Piliponsky AM, Altemeier WA, Larmore M, Frevert CW, Mulligan MS, Ziegler SF, Debley JS, Peters MC, Hallstrand TS.

J Clin Invest. 2019 Oct 14. pii: 126402. doi: 10.1172/JCI126402. [Epub ahead of print]


Length summation in noise.

Chen CC, Yeh YC, Tyler CW.

J Vis. 2019 Aug 1;19(9):11. doi: 10.1167/19.9.11.


ASIC3-dependent metabolomics profiling of serum and urine in a mouse model of fibromyalgia.

Hsu WH, Lee CH, Chao YM, Kuo CH, Ku WC, Chen CC, Lin YL.

Sci Rep. 2019 Aug 20;9(1):12123. doi: 10.1038/s41598-019-48315-w.


Activation of Aryl Hydrocarbon Receptor by Kynurenine Impairs Progression and Metastasis of Neuroblastoma.

Wu PY, Yu IS, Lin YC, Chang YT, Chen CC, Lin KH, Tseng TH, Kargren M, Tai YL, Shen TL, Liu YL, Wang BJ, Chang CH, Chen WM, Juan HF, Huang SF, Chan YY, Liao YF, Hsu WM, Lee H.

Cancer Res. 2019 Aug 20. pii: canres.3272.2018. doi: 10.1158/0008-5472.CAN-18-3272. [Epub ahead of print]


Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age.

Mehdipour M, Etienne J, Chen CC, Gathwala R, Rehman M, Kato C, Liu C, Liu Y, Zuo Y, Conboy MJ, Conboy IM.

Aging (Albany NY). 2019 Aug 15;11(15):5628-5645. doi: 10.18632/aging.102148. Epub 2019 Aug 15.


Activation of the NLRP3 and AIM2 inflammasomes in a mouse model of Schistosoma mansoni infection.

Chen TTW, Cheng PC, Chang KC, Cao JP, Feng JL, Chen CC, Lam HYP, Peng SY.

J Helminthol. 2019 Aug 15:1-9. doi: 10.1017/S0022149X19000622. [Epub ahead of print]


Application of Helicobacter pylori stool antigen test to survey the updated prevalence of H. pylori infection in Taiwan.

Chen MJ, Fang YJ, Wu MS, Chen CC, Chen YN, Yu CC, Kuo CC, Chiu MC, Hu WH, Tsai MH, Hsieh CL, Chen HH, Bair MJ, Liou JM; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

J Gastroenterol Hepatol. 2019 Aug 13. doi: 10.1111/jgh.14828. [Epub ahead of print]


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