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Multi-domain cognitive assessment of male mice shows space radiation is not harmful to high-level cognition and actually improves pattern separation.

Whoolery CW, Yun S, Reynolds RP, Lucero MJ, Soler I, Tran FH, Ito N, Redfield RL, Richardson DR, Shih HY, Rivera PD, Chen BPC, Birnbaum SG, Stowe AM, Eisch AJ.

Sci Rep. 2020 Feb 17;10(1):2737. doi: 10.1038/s41598-020-59419-z.


DNA-dependent protein kinase in telomere maintenance and protection.

Sui J, Zhang S, Chen BPC.

Cell Mol Biol Lett. 2020 Jan 17;25:2. doi: 10.1186/s11658-020-0199-0. eCollection 2020.


Capturing adverse events in elective orthopedic surgery: comparison of administrative, surgeon and reviewer reporting

Garland K, Chen BP, Poitras S, Wai EK, Kingwell SP, Roffey DM, Beaulé PE.

Can J Surg. 2020 Jan 22;63(1):E35-E37. doi: 10.1503/cjs.019117.


RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer.

Yenerall P, Das AK, Wang S, Kollipara RK, Li LS, Villalobos P, Flaming J, Lin YF, Huffman K, Timmons BC, Gilbreath C, Sonavane R, Kinch LN, Rodriguez-Canales J, Moran C, Behrens C, Hirasawa M, Takata T, Murakami R, Iwanaga K, Chen BPC, Grishin NV, Raj GV, Wistuba II, Minna JD, Kittler R.

Cell Chem Biol. 2020 Jan 16;27(1):105-121.e14. doi: 10.1016/j.chembiol.2019.12.005. Epub 2019 Dec 26.


Vanillin derivative VND3207 activates DNA-PKcs conferring protection against radiation-induced intestinal epithelial cells injury in vitro and in vivo.

Li M, Lang Y, Gu MM, Shi J, Chen BPC, Yu L, Zhou PK, Shang ZF.

Toxicol Appl Pharmacol. 2020 Jan 15;387:114855. doi: 10.1016/j.taap.2019.114855. Epub 2019 Dec 9.


Selective Dorsal Rhizotomy for the Treatment of Gait Dysfunction in Cerebral Palsy: A Critical Analysis Review.

Chen BP, Wang KK, Novacheck TF.

JBJS Rev. 2019 Nov;7(11):e3. doi: 10.2106/JBJS.RVW.19.00020. No abstract available.


Lysophosphatidic acid receptor LPA3 prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome.

Chen WM, Chiang JC, Lin YC, Lin YN, Chuang PY, Chang YC, Chen CC, Wu KY, Hsieh JC, Chen SK, Huang WP, Chen BPC, Lee H.

Aging Cell. 2020 Jan;19(1):e13064. doi: 10.1111/acel.13064. Epub 2019 Nov 12.


The vanillin derivative VND3207 protects intestine against radiation injury by modulating p53/NOXA signaling pathway and restoring the balance of gut microbiota.

Li M, Gu MM, Lang Y, Shi J, Chen BPC, Guan H, Yu L, Zhou PK, Shang ZF.

Free Radic Biol Med. 2019 Dec;145:223-236. doi: 10.1016/j.freeradbiomed.2019.09.035. Epub 2019 Sep 30.


Exosomal microRNA-16-5p from human urine-derived stem cells ameliorates diabetic nephropathy through protection of podocyte.

Duan YR, Chen BP, Chen F, Yang SX, Zhu CY, Ma YL, Li Y, Shi J.

J Cell Mol Med. 2019 Sep 30. doi: 10.1111/jcmm.14558. [Epub ahead of print]


Global hospital and operative costs associated with various ventral cavity procedures: a comprehensive literature review and analysis across regions.

Chen BP, Clymer JW, Turner AP, Ferko N.

J Med Econ. 2019 Nov;22(11):1210-1220. doi: 10.1080/13696998.2019.1661680. Epub 2019 Sep 14.


Clinical and economic outcomes of cesarean deliveries with skin closure through skin staples plus waterproof wound dressings versus 2-octyl cyanoacrylate plus polymer mesh tape.

Johnston SS, Chen BP, Nayak A, Lee SHY, Costa M, Tommaselli GA.

J Matern Fetal Neonatal Med. 2019 Aug 1:1-10. doi: 10.1080/14767058.2019.1645830. [Epub ahead of print]


A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments.

Kuo CT, Wang JY, Lu SR, Lai YS, Chang HH, Hsieh JT, Wo AM, Chen BPC, Lu JH, Lee H.

Sci Rep. 2019 Jul 12;9(1):10120. doi: 10.1038/s41598-019-46502-3.


Comparing the effects of two spasticity management strategies on the long-term outcomes of individuals with bilateral spastic cerebral palsy: a multicentre cohort study protocol.

Munger ME, Chen BP, MacWilliams BA, McMulkin ML, Schwartz MH.

BMJ Open. 2019 Jun 20;9(6):e027486. doi: 10.1136/bmjopen-2018-027486.


LncRNA MALAT1 inhibits osteogenic differentiation of mesenchymal stem cells in osteoporosis rats through MAPK signaling pathway.

Zheng S, Wang YB, Yang YL, Chen BP, Wang CX, Li RH, Huang D.

Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4609-4617. doi: 10.26355/eurrev_201906_18038.


Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.

Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ.

Nature. 2019 May;569(7756):E4. doi: 10.1038/s41586-019-1133-3.


Downregulation of Human DAB2IP Gene Expression in Renal Cell Carcinoma Results in Resistance to Ionizing Radiation.

Yun EJ, Lin CJ, Dang A, Hernandez E, Guo J, Chen WM, Allison J, Kim N, Kapur P, Brugarolas J, Wu K, He D, Lai CH, Lin H, Saha D, Baek ST, Chen BPC, Hsieh JT.

Clin Cancer Res. 2019 Jul 15;25(14):4542-4551. doi: 10.1158/1078-0432.CCR-18-3004. Epub 2019 Apr 18.


Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.

Han Y, Wu P, Wang Z, Zhang Z, Sun S, Liu J, Gong S, Gao P, Iwakuma T, Molina-Vila MA, Chen BP, Zhang Y, Ji T, Mo Q, Chen P, Hu J, Wang S, Zhou J, Lu H, Gao Q.

EBioMedicine. 2019 Feb;40:92-105. doi: 10.1016/j.ebiom.2019.01.002. Epub 2019 Jan 20.


The popliteal angle tests in patients with cerebral palsy.

Manikowska F, Chen BP, Jóźwiak M, Lebiedowska MK.

J Pediatr Orthop B. 2019 Jul;28(4):332-336. doi: 10.1097/BPB.0000000000000579.


High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells.

Huang YL, Lin YC, Lin CC, Chen WM, Chen BPC, Lee H.

Cell Physiol Biochem. 2018;50(2):597-611. doi: 10.1159/000494177. Epub 2018 Oct 12.


Whole-Body 12C Irradiation Transiently Decreases Mouse Hippocampal Dentate Gyrus Proliferation and Immature Neuron Number, but Does Not Change New Neuron Survival Rate.

Zanni G, Deutsch HM, Rivera PD, Shih HY, LeBlanc JA, Amaral WZ, Lucero MJ, Redfield RL, DeSalle MJ, Chen BPC, Whoolery CW, Reynolds RP, Yun S, Eisch AJ.

Int J Mol Sci. 2018 Oct 9;19(10). pii: E3078. doi: 10.3390/ijms19103078.


Selective dorsal rhizotomy in ambulant children with cerebral palsy.

Wang KK, Munger ME, Chen BP, Novacheck TF.

J Child Orthop. 2018 Oct 1;12(5):413-427. doi: 10.1302/1863-2548.12.180123.


The Relative Biological Effect of Spread-Out Bragg Peak Protons in Sensitive and Resistant Tumor Cells.

Lin YF, Chen BP, Li W, Perko Z, Wang Y, Testa M, Schneider R, Lu HM, Gerweck LE.

Int J Part Ther. 2018 Winter;4(3):33-39. doi: 10.14338/IJPT-17-00025.1. Epub 2018 Mar 21.


Patchy increased echogenicity: a sonographic sign of femoral head necrosis following reduction and casting for developmental dysplasia of the hip.

Chen BP, Harcke HT, Bowen JR.

Pediatr Radiol. 2018 Dec;48(13):1971-1974. doi: 10.1007/s00247-018-4212-y. Epub 2018 Jul 28.


Facilitating tumor spheroid-based bioassays and in vitro blood vessel modeling via bioinspired self-formation microstructure devices.

Kuo CT, Lu SR, Chen WM, Wang JY, Lee SC, Chang HH, Wo AM, Chen BPC, Lee H.

Lab Chip. 2018 Aug 7;18(16):2453-2465. doi: 10.1039/c8lc00423d.


Comparison of three-dimensional multi-segmental foot models used in clinical gait laboratories.

Nicholson K, Church C, Takata C, Niiler T, Chen BP, Lennon N, Sees JP, Henley J, Miller F.

Gait Posture. 2018 Jun;63:236-241. doi: 10.1016/j.gaitpost.2018.05.013. Epub 2018 May 16.


Systematic Review and Meta-analysis of Restrictive Perioperative Fluid Management in Pancreaticoduodenectomy.

Chen BP, Chen M, Bennett S, Lemon K, Bertens KA, Balaa FK, Martel G.

World J Surg. 2018 Sep;42(9):2938-2950. doi: 10.1007/s00268-018-4545-6. Review.


Validation of Manual Muscle Testing (MMT) in children and adolescents with cerebral palsy.

Manikowska F, Chen BP, Jóźwiak M, Lebiedowska MK.

NeuroRehabilitation. 2018;42(1):1-7. doi: 10.3233/NRE-172179.


PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway.

Lin YF, Shih HY, Shang ZF, Kuo CT, Guo J, Du C, Lee H, Chen BPC.

Nucleic Acids Res. 2018 Feb 28;46(4):1847-1859. doi: 10.1093/nar/gkx1298.


MicroRNA-21 promotes the progression of peritoneal fibrosis through the activation of the TGF-β/Smad signaling pathway: An in vitro and in vivo study.

Ma YL, Chen F, Yang SX, Chen BP, Shi J.

Int J Mol Med. 2018 Feb;41(2):1030-1038. doi: 10.3892/ijmm.2017.3268. Epub 2017 Nov 17.


Whole-Body Exposure to 28Si-Radiation Dose-Dependently Disrupts Dentate Gyrus Neurogenesis and Proliferation in the Short Term and New Neuron Survival and Contextual Fear Conditioning in the Long Term.

Whoolery CW, Walker AK, Richardson DR, Lucero MJ, Reynolds RP, Beddow DH, Clark KL, Shih HY, LeBlanc JA, Cole MG, Amaral WZ, Mukherjee S, Zhang S, Ahn F, Bulin SE, DeCarolis NA, Rivera PD, Chen BPC, Yun S, Eisch AJ.

Radiat Res. 2017 Nov;188(5):532-551. doi: 10.1667/RR14797.1. Epub 2017 Sep 25.


Use and acceptance of the International Study Group for Pancreatic Fistula (ISGPF) definition and criteria in the surgical literature.

Chen BP, Bennett S, Bertens KA, Balaa FK, Martel G.

HPB (Oxford). 2018 Jan;20(1):69-75. doi: 10.1016/j.hpb.2017.08.022. Epub 2017 Sep 18.


Prolonged Operative Duration Increases Risk of Surgical Site Infections: A Systematic Review.

Cheng H, Chen BP, Soleas IM, Ferko NC, Cameron CG, Hinoul P.

Surg Infect (Larchmt). 2017 Aug/Sep;18(6):722-735. doi: 10.1089/sur.2017.089. Review.


Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation.

Yin Y, Li R, Xu K, Ding S, Li J, Baek G, Ramanand SG, Ding S, Liu Z, Gao Y, Kanchwala MS, Li X, Hutchinson R, Liu X, Woldu SL, Xing C, Desai NB, Feng FY, Burma S, de Bono JS, Dehm SM, Mani RS, Chen BPC, Raj GV.

Cancer Res. 2017 Sep 15;77(18):4745-4754. doi: 10.1158/0008-5472.CAN-17-0164. Epub 2017 Jul 28.


Impact of Definition and Timeframe on Capturing Surgery-Related Readmissions After Primary Joint Arthroplasty.

Chen BP, Dobransky J, Poitras S, Forster A, Beaulé PE.

J Arthroplasty. 2017 Dec;32(12):3563-3567. doi: 10.1016/j.arth.2017.06.039. Epub 2017 Jul 5.


Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array.

Kuo CT, Wang JY, Lin YF, Wo AM, Chen BPC, Lee H.

Sci Rep. 2017 Jun 29;7(1):4363. doi: 10.1038/s41598-017-04718-1.


Looping-out mechanism for resolution of replicative stress at telomeres.

Zhang T, Zhang Z, Li F, Hu Q, Liu H, Tang M, Ma W, Huang J, Songyang Z, Rong Y, Zhang S, Chen BP, Zhao Y.

EMBO Rep. 2017 Aug;18(8):1412-1428. doi: 10.15252/embr.201643866. Epub 2017 Jun 14.


Economic burden of cancer among patients with surgical resections of the lung, rectum, liver and uterus: results from a US hospital database claims analysis.

Kalsekar I, Hsiao CW, Cheng H, Yadalam S, Chen BP, Goldstein L, Yoo A.

Health Econ Rev. 2017 Dec;7(1):22. doi: 10.1186/s13561-017-0160-8. Epub 2017 Jun 2.


CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.

Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ.

Nature. 2017 Jun 1;546(7656):168-172. doi: 10.1038/nature22359. Epub 2017 May 24. Erratum in: Nature. 2019 May;569(7756):E4.


Imaging of Fluorescently Tagged ATM Kinase at the Sites of DNA Double Strand Breaks.

Davis AJ, Wang SY, Chen DJ, Chen BPC.

Methods Mol Biol. 2017;1599:277-285. doi: 10.1007/978-1-4939-6955-5_20.


ParaStamp and Its Applications to Cell Patterning, Drug Synergy Screening, and Rewritable Devices for Droplet Storage.

Kuo CT, Wang JY, Wo AM, Chen BPC, Lee H.

Adv Biosyst. 2017 May;1(5). pii: 1700048. doi: 10.1002/adbi.201700048. Epub 2017 Apr 24.


A pilot validation study of crowdsourcing systematic reviews: update of a searchable database of pediatric clinical trials of high-dose vitamin D.

Nama N, Iliriani K, Xia MY, Chen BP, Zhou LL, Pojsupap S, Kappel C, O'Hearn K, Sampson M, Menon K, McNally JD.

Transl Pediatr. 2017 Jan;6(1):18-26. doi: 10.21037/tp.2016.12.01.


[Effects of ApoE gene polymorphism on the efficacy of atorvastatin in the treatment of hyperlipidemia].

Zhang Y, Wei DD, Yuan RR, Ge QX, Chen F, Yang SX, Chen BP, Shi J.

Zhonghua Yi Xue Za Zhi. 2017 Jan 24;97(4):291-294. doi: 10.3760/cma.j.issn.0376-2491.2017.04.011. Chinese.


Coordination of the Ser2056 and Thr2609 Clusters of DNA-PKcs in Regulating Gamma Rays and Extremely Low Fluencies of Alpha-Particle Irradiation to G0/G1 Phase Cells.

Nagasawa H, Lin YF, Kato TA, Brogan JR, Shih HY, Kurimasa A, Bedford JS, Chen BP, Little JB.

Radiat Res. 2017 Feb;187(2):259-267. doi: 10.1667/RR14679.1. Epub 2017 Jan 24.


The influence of an external breast prosthesis on the posture of women after mastectomy.

Hojan K, Manikowska F, Chen BP, Lin CC.

J Back Musculoskelet Rehabil. 2016 Apr 27;29(2):337-342.


Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments.

Yu L, Shang ZF, Abdisalaam S, Lee KJ, Gupta A, Hsieh JT, Asaithamby A, Chen BP, Saha D.

Nucleic Acids Res. 2016 Oct 14;44(18):8842-8854. Epub 2016 Aug 27.


Four-week prehabilitation program is sufficient to modify exercise behaviors and improve preoperative functional walking capacity in patients with colorectal cancer.

Chen BP, Awasthi R, Sweet SN, Minnella EM, Bergdahl A, Santa Mina D, Carli F, Scheede-Bergdahl C.

Support Care Cancer. 2017 Jan;25(1):33-40. Epub 2016 Aug 18.


Can Surgeons Adequately Capture Adverse Events Using the Spinal Adverse Events Severity System (SAVES) and OrthoSAVES?

Chen BP, Garland K, Roffey DM, Poitras S, Dervin G, Lapner P, Phan P, Wai EK, Kingwell SP, Beaulé PE.

Clin Orthop Relat Res. 2017 Jan;475(1):253-260. doi: 10.1007/s11999-016-5021-y. Epub 2016 Aug 10.


Knee Deformities in Children With Down Syndrome: A Focus on Knee Malalignment.

Duque Orozco MDP, Abousamra O, Chen BP, Rogers KJ, Sees JP, Miller F.

J Pediatr Orthop. 2018 May/Jun;38(5):266-273. doi: 10.1097/BPO.0000000000000814.


IL-16 rs4778889 polymorphism contribution to the development of renal cell cancer in a Chinese population.

Yang SX, Chen F, Zhang JW, Sun ZQ, Chen BP.

Genet Mol Res. 2016 Jun 10;15(2). doi: 10.4238/gmr.15027553.

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