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Protonation state of the selectivity filter of bacterial voltage-gated sodium channels is modulated by ions.

Damjanovic A, Chen AY, Rosenberg RL, Roe DR, Wu X, Brooks BR.

Proteins. 2019 Oct 7. doi: 10.1002/prot.25831. [Epub ahead of print]


AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injury.

Charsar BA, Brinton MA, Locke K, Chen AY, Ghosh B, Urban MW, Komaravolu S, Krishnamurthy K, Smit R, Pasinelli P, Wright MC, Smith GM, Lepore AC.

FASEB J. 2019 Oct 2:fj201901730R. doi: 10.1096/fj.201901730R. [Epub ahead of print]


Head and Neck Cancer Detection in Digitized Whole-Slide Histology Using Convolutional Neural Networks.

Halicek M, Shahedi M, Little JV, Chen AY, Myers LL, Sumer BD, Fei B.

Sci Rep. 2019 Oct 1;9(1):14043. doi: 10.1038/s41598-019-50313-x.


Rapid Induction and Maintenance of Remission in Refractory Ulcerative Colitis with Ustekinumab.

Chen AY, Oz HS.

Diseases. 2019 Sep 28;7(4). pii: E55. doi: 10.3390/diseases7040055.


Hyperspectral Imaging of Head and Neck Squamous Cell Carcinoma for Cancer Margin Detection in Surgical Specimens from 102 Patients Using Deep Learning.

Halicek M, Dormer JD, Little JV, Chen AY, Myers L, Sumer BD, Fei B.

Cancers (Basel). 2019 Sep 14;11(9). pii: E1367. doi: 10.3390/cancers11091367.


Readmissions After Acute Myocardial Infarction: How Often Do Patients Return to the Discharging Hospital?

Rymer JA, Chen AY, Thomas L, Fonarow GC, Peterson ED, Wang TY.

J Am Heart Assoc. 2019 Oct;8(19):e012059. doi: 10.1161/JAHA.119.012059. Epub 2019 Sep 20.


Hyperspectral imaging for head and neck cancer detection: specular glare and variance of the tumor margin in surgical specimens.

Halicek M, Fabelo H, Ortega S, Little JV, Wang X, Chen AY, Callico GM, Myers L, Sumer BD, Fei B.

J Med Imaging (Bellingham). 2019 Jul;6(3):035004. doi: 10.1117/1.JMI.6.3.035004. Epub 2019 Sep 14.


Redirecting, Without Dampening, the Enthusiasm of Surgeons.

Chen AY.

JAMA Otolaryngol Head Neck Surg. 2019 Aug 29. doi: 10.1001/jamaoto.2019.2404. [Epub ahead of print] No abstract available.


Association of Cognitive Impairment With Treatment and Outcomes in Older Myocardial Infarction Patients: A Report From the NCDR Chest Pain-MI Registry.

Bagai A, Chen AY, Udell JA, Dodson JA, McManus DD, Maurer MS, Enriquez JR, Hochman J, Goyal A, Henry TD, Gulati M, Garratt KN, Roe MT, Alexander KP.

J Am Heart Assoc. 2019 Sep 3;8(17):e012929. doi: 10.1161/JAHA.119.012929. Epub 2019 Aug 29.


Dermatology residents in the era of #MeToo: Ethical considerations of appropriate responses to inappropriate patient behavior.

Mattessich S, Chiaravalloti A, Chen AY.

Int J Womens Dermatol. 2019 Jan 24;5(3):175-176. doi: 10.1016/j.ijwd.2019.01.004. eCollection 2019 Jul. No abstract available.


Hospital participation in clinical trials for patients with acute myocardial infarction: Results from the National Cardiovascular Data Registry.

Fanaroff AC, Vora AN, Chen AY, Mathews R, Udell JA, Roe MT, Thomas LE, Wang TY.

Am Heart J. 2019 Aug;214:184-193. doi: 10.1016/j.ahj.2019.05.011. Epub 2019 May 25.


Discovery of a Lead Triphenylethanamine Cholesterol Ester Transfer Protein (CETP) Inhibitor.

Finlay HJ, Jiang J, Rampulla R, Salvati ME, Qiao JX, Wang TC, Lawrence RM, Harikrishnan LS, Kamau MG, Taylor DS, Chen AYA, Yin X, Huang CS, Chang M, Chen XQ, Sleph PG, Xu C, Li J, Levesque P, Adam LP, Wexler RR.

ACS Med Chem Lett. 2019 May 6;10(6):911-916. doi: 10.1021/acsmedchemlett.9b00086. eCollection 2019 Jun 13.


Symmetric red-purple papules in the diaper region.

Weston G, Chen AY.

JAAD Case Rep. 2019 May 8;5(5):439-440. doi: 10.1016/j.jdcr.2019.02.018. eCollection 2019 May. No abstract available.


Correction to Targeting Metalloenzymes for Therapeutic Intervention.

Chen AY, Adamek RN, Dick BL, Credille CV, Morrison CN, Cohen SM.

Chem Rev. 2019 Jun 11. doi: 10.1021/acs.chemrev.9b00322. [Epub ahead of print] No abstract available.


Effects of Online Care on Functional and Psychological Outcomes in Patients with Psoriasis: A Randomized Controlled Trial.

Young PM, Chen AY, Ford AR, Cheng MY, Lane CJ, Armstrong AW.

J Am Acad Dermatol. 2019 Jun 5. pii: S0190-9622(19)30893-X. doi: 10.1016/j.jaad.2019.05.089. [Epub ahead of print]


Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo-β-Lactamases.

Chen AY, Thomas PW, Cheng Z, Xu NY, Tierney DL, Crowder MW, Fast W, Cohen SM.

ChemMedChem. 2019 Jul 3;14(13):1271-1282. doi: 10.1002/cmdc.201900172. Epub 2019 May 24.


Social context influences sensorimotor gating in female African cichlid fish Astatotilapia burtoni.

Adelman M, Chen AY, Aberg A, Neumeister H, Preuss T.

Behav Brain Res. 2019 Sep 16;370:111925. doi: 10.1016/j.bbr.2019.111925. Epub 2019 May 15.


Enhanced safety and immunogenicity of a pneumococcal surface antigen A mutant whole-cell inactivated pneumococcal vaccine.

David SC, Laan Z, Minhas V, Chen AY, Davies J, Hirst TR, McColl SR, Alsharifi M, Paton JC.

Immunol Cell Biol. 2019 Sep;97(8):726-739. doi: 10.1111/imcb.12257. Epub 2019 May 23.


T4 Laryngeal Cancer With Good Function: Should We Be Reluctant to Treat Without Surgery?

Beitler JJ, Ridge JA, Vermorken JB, Bradford CR, Strojan P, Saba NF, Suárez C, Rodrigo JP, Rinaldo A, Chen AY, Ferlito A.

Int J Radiat Oncol Biol Phys. 2018 Dec 1;102(5):1400-1403. doi: 10.1016/j.ijrobp.2018.03.007. No abstract available.


Children and thyroid cancer: Interpreting troubling trends.

Chen AY, Davies L.

Cancer. 2019 Jul 15;125(14):2359-2361. doi: 10.1002/cncr.32124. Epub 2019 Apr 23. No abstract available.


Intensive Care Utilization in Stable Patients With ST-Segment Elevation Myocardial Infarction Treated With Rapid Reperfusion.

Shavadia JS, Chen AY, Fanaroff AC, de Lemos JA, Kontos MC, Wang TY.

JACC Cardiovasc Interv. 2019 Apr 22;12(8):709-717. doi: 10.1016/j.jcin.2019.01.230.


VATS Resection of Large Ectopic Posterior Mediastinal Cystic Parathyroid Adenoma.

Medbery RL, Winters A, Chen AY, Rogers TE, Force SD.

Ann Thorac Surg. 2019 Apr 9. pii: S0003-4975(19)30510-7. doi: 10.1016/j.athoracsur.2019.03.029. [Epub ahead of print]


Scale law of complex deformation transitions of nanotwins in stainless steel.

Chen AY, Zhu LL, Sun LG, Liu JB, Wang HT, Wang XY, Yang JH, Lu J.

Nat Commun. 2019 Mar 29;10(1):1403. doi: 10.1038/s41467-019-09360-1.


Assessment of Gender Differences in Perceptions of Work-Life Integration Among Head and Neck Surgeons.

Tulunay-Ugur OE, Sinclair CF, Chen AY.

JAMA Otolaryngol Head Neck Surg. 2019 May 1;145(5):453-458. doi: 10.1001/jamaoto.2019.0104.


Optical biopsy of head and neck cancer using hyperspectral imaging and convolutional neural networks.

Halicek M, Little JV, Wang X, Chen AY, Fei B.

J Biomed Opt. 2019 Mar;24(3):1-9. doi: 10.1117/1.JBO.24.3.036007.


Highly-efficient luminol immobilization approach and exponential strand displacement reaction based electrochemiluminescent strategy for monitoring microRNA expression in cell.

Yuan Y, Li X, Chen AY, Wang HJ, Chai YQ, Yuan R.

Biosens Bioelectron. 2019 May 1;132:62-67. doi: 10.1016/j.bios.2019.02.005. Epub 2019 Feb 23.


High expression of carbonic anhydrase 12 (CA12) is associated with good prognosis in breast cancer.

Li Y, Lei B, Zou J, Wang W, Chen A, Zhang J, Fu Y, Li Z.

Neoplasma. 2019 May 23;66(3):420-426. doi: 10.4149/neo_2018_180819N624. Epub 2019 Feb 14.


Novel Ru(bpy)2(cpaphen)2+/TPrA/TiO2 Ternary ECL System: An Efficient Platform for the Detection of Glutathione with Mn2+ as Substitute Target.

Zhang R, Zhong X, Chen AY, Liu JL, Li SK, Chai YQ, Zhuo Y, Yuan R.

Anal Chem. 2019 Mar 5;91(5):3681-3686. doi: 10.1021/acs.analchem.8b05795. Epub 2019 Feb 11.


Doping effect and fluorescence quenching mechanism of N-doped graphene quantum dots in the detection of dopamine.

Ma Y, Chen AY, Xie XF, Wang XY, Wang D, Wang P, Li HJ, Yang JH, Li Y.

Talanta. 2019 May 1;196:563-571. doi: 10.1016/j.talanta.2019.01.001. Epub 2019 Jan 3.


Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase.

Johnson JA, Tora G, Pi Z, Phillips M, Yin X, Yang R, Zhao L, Chen AY, Taylor DS, Basso M, Rose A, Behnia K, Onorato J, Chen XQ, Abell LM, Lu H, Locke G, Caporuscio C, Galella M, Adam LP, Gordon D, Wexler RR, Finlay HJ.

ACS Med Chem Lett. 2018 Nov 21;9(12):1263-1268. doi: 10.1021/acsmedchemlett.8b00424. eCollection 2018 Dec 13.


Down-regulated expression of LINC00518 prevents epithelial cell growth and metastasis in breast cancer through the inhibition of CDX2 methylation and the Wnt signaling pathway.

Wang HB, Wei H, Wang JS, Li L, Chen AY, Li ZG.

Biochim Biophys Acta Mol Basis Dis. 2019 Mar 1;1865(3):708-723. doi: 10.1016/j.bbadis.2019.01.003. Epub 2019 Jan 4.


Prognostic implications of peritumoral vasculature in head and neck cancer.

Evans M, Baddour HM Jr, Magliocca KR, Müller S, Nannapaneni S, Chen AY, Kim S, Chen Z, Shin DM, Wang AY, Saba NF, Chen ZG.

Cancer Med. 2019 Jan;8(1):147-154. doi: 10.1002/cam4.1910. Epub 2018 Dec 21.


Patterns of use of targeted temperature management for acute myocardial infarction patients following out-of-hospital cardiac arrest: Insights from the National Cardiovascular Data Registry.

Fordyce CB, Chen AY, Wang TY, Lucas J, Goyal A, Wong GC, van Diepen S, Kontos MC, Henry TD, Granger CB, Roe MT.

Am Heart J. 2018 Dec;206:131-133. doi: 10.1016/j.ahj.2018.08.013. Epub 2018 Sep 24.


The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction: Insights From the ACTION Registry.

Dodson JA, Hochman JS, Roe MT, Chen AY, Chaudhry SI, Katz S, Zhong H, Radford MJ, Udell JA, Bagai A, Fonarow GC, Gulati M, Enriquez JR, Garratt KN, Alexander KP.

JACC Cardiovasc Interv. 2018 Nov 26;11(22):2287-2296. doi: 10.1016/j.jcin.2018.08.028. Erratum in: JACC Cardiovasc Interv. 2019 Apr 8;12(7):695-696.


Advanced Practice Provider Versus Physician-Only Outpatient Follow-Up After Acute Myocardial Infarction.

Rymer JA, Chen AY, Thomas L, Stafford J, Enriquez JR, Goyal A, Peterson ED, Wang TY.

J Am Heart Assoc. 2018 Sep 4;7(17):e008481. doi: 10.1161/JAHA.117.008481.


Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.

Hu CH, Wang TC, Qiao JX, Haque L, Chen AYA, Taylor DS, Ying X, Onorato JM, Galella M, Shen H, Huang CS, Toussaint N, Li YX, Abell L, Adam LP, Gordon D, Wexler RR, Finlay HJ.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3721-3725. doi: 10.1016/j.bmcl.2018.10.022. Epub 2018 Oct 15.


Estimating the hospital costs of inpatient harms.

Anand P, Kranker K, Chen AY.

Health Serv Res. 2019 Feb;54(1):86-96. doi: 10.1111/1475-6773.13066. Epub 2018 Oct 11.


International neuromonitoring study group guidelines 2018: Part II: Optimal recurrent laryngeal nerve management for invasive thyroid cancer-incorporation of surgical, laryngeal, and neural electrophysiologic data.

Wu CW, Dionigi G, Barczynski M, Chiang FY, Dralle H, Schneider R, Al-Quaryshi Z, Angelos P, Brauckhoff K, Brooks JA, Cernea CR, Chaplin J, Chen AY, Davies L, Diercks GR, Duh QY, Fundakowski C, Goretzki PE, Hales NW, Hartl D, Kamani D, Kandil E, Kyriazidis N, Liddy W, Miyauchi A, Orloff L, Rastatter JC, Scharpf J, Serpell J, Shin JJ, Sinclair CF, Stack BC Jr, Tolley NS, Slycke SV, Snyder SK, Urken ML, Volpi E, Witterick I, Wong RJ, Woodson G, Zafereo M, Randolph GW.

Laryngoscope. 2018 Oct;128 Suppl 3:S18-S27. doi: 10.1002/lary.27360. Epub 2018 Oct 6.


The 11-Kilodalton Nonstructural Protein of Human Parvovirus B19 Facilitates Viral DNA Replication by Interacting with Grb2 through Its Proline-Rich Motifs.

Xu P, Chen AY, Ganaie SS, Cheng F, Shen W, Wang X, Kleiboeker S, Li Y, Qiu J.

J Virol. 2018 Dec 10;93(1). pii: e01464-18. doi: 10.1128/JVI.01464-18. Print 2019 Jan 1.


Tumor Margin Classification of Head and Neck Cancer Using Hyperspectral Imaging and Convolutional Neural Networks.

Halicek M, Little JV, Wang X, Patel M, Griffith CC, Chen AY, Fei B.

Proc SPIE Int Soc Opt Eng. 2018 Feb;10576. pii: 1057605. doi: 10.1117/12.2293167. Epub 2018 Mar 12.


Association Between Cardiac Catheterization Laboratory Pre-Activation and Reperfusion Timing Metrics and Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: A Report From the ACTION Registry.

Shavadia JS, Roe MT, Chen AY, Lucas J, Fanaroff AC, Kochar A, Fordyce CB, Jollis JG, Tamis-Holland J, Henry TD, Bagai A, Kontos MC, Granger CB, Wang TY.

JACC Cardiovasc Interv. 2018 Sep 24;11(18):1837-1847. doi: 10.1016/j.jcin.2018.07.020.


Deformable Registration of Histological Cancer Margins to Gross Hyperspectral Images using Demons.

Halicek M, Little JV, Wang X, Chen ZG, Patel M, Griffith CC, El-Deiry MW, Saba NF, Chen AY, Fei B.

Proc SPIE Int Soc Opt Eng. 2018 Feb;10581. pii: 105810N. doi: 10.1117/12.2293165. Epub 2018 Mar 6.


Transcriptional Responses to ppGpp and DksA.

Gourse RL, Chen AY, Gopalkrishnan S, Sanchez-Vazquez P, Myers A, Ross W.

Annu Rev Microbiol. 2018 Sep 8;72:163-184. doi: 10.1146/annurev-micro-090817-062444. Review.


Optical Biopsy of Head and Neck Cancer Using Hyperspectral Imaging and Convolutional Neural Networks.

Halicek M, Little JV, Wang X, Patel M, Griffith CC, El-Deiry MW, Chen AY, Fei B.

Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb;10469. pii: 104690X. doi: 10.1117/12.2289023. Epub 2018 Feb 12.


Targeting Metalloenzymes for Therapeutic Intervention.

Chen AY, Adamek RN, Dick BL, Credille CV, Morrison CN, Cohen SM.

Chem Rev. 2019 Jan 23;119(2):1323-1455. doi: 10.1021/acs.chemrev.8b00201. Epub 2018 Sep 7. Erratum in: Chem Rev. 2019 Jun 11;:.


Autoimmune blistering disorders in the setting of human immunodeficiency virus infection.

Min MS, Damstetter E, Chen AYY.

Int J Womens Dermatol. 2018 Jun 11;4(3):159-165. doi: 10.1016/j.ijwd.2018.02.002. eCollection 2018 Sep. Review.


Sodium Channel SCN3A (NaV1.3) Regulation of Human Cerebral Cortical Folding and Oral Motor Development.

Smith RS, Kenny CJ, Ganesh V, Jang A, Borges-Monroy R, Partlow JN, Hill RS, Shin T, Chen AY, Doan RN, Anttonen AK, Ignatius J, Medne L, Bönnemann CG, Hecht JL, Salonen O, Barkovich AJ, Poduri A, Wilke M, de Wit MCY, Mancini GMS, Sztriha L, Im K, Amrom D, Andermann E, Paetau R, Lehesjoki AE, Walsh CA, Lehtinen MK.

Neuron. 2018 Sep 5;99(5):905-913.e7. doi: 10.1016/j.neuron.2018.07.052. Epub 2018 Aug 23.

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