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Items: 37


Structure of Ddi2, a highly inducible detoxifying metalloenzyme from Saccharomyces cerevisiae.

Li J, Jia Y, Lin A, Hanna M, Chelico L, Xiao W, Moore SA.

J Biol Chem. 2019 Jul 5;294(27):10674-10685. doi: 10.1074/jbc.RA118.006394. Epub 2019 May 31.


Role of co-expressed APOBEC3F and APOBEC3G in inducing HIV-1 drug resistance.

Mohammadzadeh N, Love RP, Gibson R, Arts EJ, Poon AFY, Chelico L.

Heliyon. 2019 Apr 16;5(4):e01498. doi: 10.1016/j.heliyon.2019.e01498. eCollection 2019 Apr.


APOBEC3 Host Restriction Factors of HIV-1 Can Change the Template Switching Frequency of Reverse Transcriptase.

Adolph MB, Ara A, Chelico L.

J Mol Biol. 2019 Mar 29;431(7):1339-1352. doi: 10.1016/j.jmb.2019.02.015. Epub 2019 Feb 22.


Polymorphisms of the cytidine deaminase APOBEC3F have different HIV-1 restriction efficiencies.

Mohammadzadeh N, Follack TB, Love RP, Stewart K, Sanche S, Chelico L.

Virology. 2019 Jan 15;527:21-31. doi: 10.1016/j.virol.2018.11.004. Epub 2018 Nov 15.


RNA-Mediated Dimerization of the Human Deoxycytidine Deaminase APOBEC3H Influences Enzyme Activity and Interaction with Nucleic Acids.

Feng Y, Wong L, Morse M, Rouzina I, Williams MC, Chelico L.

J Mol Biol. 2018 Dec 7;430(24):4891-4907. doi: 10.1016/j.jmb.2018.11.006. Epub 2018 Nov 9.


Corrigendum: Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B.

Adolph MB, Love RP, Feng Y, Chelico L.

Nucleic Acids Res. 2018 Dec 14;46(22):12190-12191. doi: 10.1093/nar/gky1115. No abstract available.


Biochemical Basis of APOBEC3 Deoxycytidine Deaminase Activity on Diverse DNA Substrates.

Adolph MB, Love RP, Chelico L.

ACS Infect Dis. 2018 Mar 9;4(3):224-238. doi: 10.1021/acsinfecdis.7b00221. Epub 2018 Feb 9.


Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B.

Adolph MB, Love RP, Feng Y, Chelico L.

Nucleic Acids Res. 2017 Nov 16;45(20):11925-11940. doi: 10.1093/nar/gkx832. Erratum in: Nucleic Acids Res. 2018 Dec 14;46(22):12190-12191.


Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G.

Morse M, Huo R, Feng Y, Rouzina I, Chelico L, Williams MC.

Nat Commun. 2017 Sep 19;8(1):597. doi: 10.1038/s41467-017-00501-y.


Deamination-independent restriction of LINE-1 retrotransposition by APOBEC3H.

Feng Y, Goubran MH, Follack TB, Chelico L.

Sci Rep. 2017 Sep 7;7(1):10881. doi: 10.1038/s41598-017-11344-4.


Correction for Baig et al., Determinants of Efficient Degradation of APOBEC3 Restriction Factors by HIV-1 Vif.

Baig TT, Feng Y, Chelico L.

J Virol. 2017 Mar 13;91(7). pii: e00079-17. doi: 10.1128/JVI.00079-17. Print 2017 Apr 1. No abstract available.


Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization.

Adolph MB, Ara A, Feng Y, Wittkopp CJ, Emerman M, Fraser JS, Chelico L.

Nucleic Acids Res. 2017 Apr 7;45(6):3378-3394. doi: 10.1093/nar/gkx066.


Mechanism of Enhanced HIV Restriction by Virion Coencapsidated Cytidine Deaminases APOBEC3F and APOBEC3G.

Ara A, Love RP, Follack TB, Ahmed KA, Adolph MB, Chelico L.

J Virol. 2017 Jan 18;91(3). pii: e02230-16. doi: 10.1128/JVI.02230-16. Print 2017 Feb 1.


A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses.

Wittkopp CJ, Adolph MB, Wu LI, Chelico L, Emerman M.

PLoS Pathog. 2016 Oct 12;12(10):e1005865. doi: 10.1371/journal.ppat.1005865. eCollection 2016 Oct.


The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis.

Starrett GJ, Luengas EM, McCann JL, Ebrahimi D, Temiz NA, Love RP, Feng Y, Adolph MB, Chelico L, Law EK, Carpenter MA, Harris RS.

Nat Commun. 2016 Sep 21;7:12918. doi: 10.1038/ncomms12918.


Natural Polymorphisms and Oligomerization of Human APOBEC3H Contribute to Single-stranded DNA Scanning Ability.

Feng Y, Love RP, Ara A, Baig TT, Adolph MB, Chelico L.

J Biol Chem. 2015 Nov 6;290(45):27188-203. doi: 10.1074/jbc.M115.666065. Epub 2015 Sep 22.


Determinants of efficient degradation of APOBEC3 restriction factors by HIV-1 Vif.

Baig TT, Feng Y, Chelico L.

J Virol. 2014 Dec;88(24):14380-95. doi: 10.1128/JVI.02484-14. Epub 2014 Oct 1. Erratum in: J Virol. 2017 Mar 13;91(7):.


Suppression of APOBEC3-mediated restriction of HIV-1 by Vif.

Feng Y, Baig TT, Love RP, Chelico L.

Front Microbiol. 2014 Aug 26;5:450. doi: 10.3389/fmicb.2014.00450. eCollection 2014. Review.


Different mutagenic potential of HIV-1 restriction factors APOBEC3G and APOBEC3F is determined by distinct single-stranded DNA scanning mechanisms.

Ara A, Love RP, Chelico L.

PLoS Pathog. 2014 Mar 20;10(3):e1004024. doi: 10.1371/journal.ppat.1004024. eCollection 2014 Mar.


Retroviral restriction factor APOBEC3G delays the initiation of DNA synthesis by HIV-1 reverse transcriptase.

Adolph MB, Webb J, Chelico L.

PLoS One. 2013 May 23;8(5):e64196. doi: 10.1371/journal.pone.0064196. Print 2013.


HIV-1 viral infectivity factor (Vif) alters processive single-stranded DNA scanning of the retroviral restriction factor APOBEC3G.

Feng Y, Love RP, Chelico L.

J Biol Chem. 2013 Mar 1;288(9):6083-94. doi: 10.1074/jbc.M112.421875. Epub 2013 Jan 11.


Biochemical analysis of hypermutation by the deoxycytidine deaminase APOBEC3A.

Love RP, Xu H, Chelico L.

J Biol Chem. 2012 Aug 31;287(36):30812-22. doi: 10.1074/jbc.M112.393181. Epub 2012 Jul 20.


Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution.

Senavirathne G, Jaszczur M, Auerbach PA, Upton TG, Chelico L, Goodman MF, Rueda D.

J Biol Chem. 2012 May 4;287(19):15826-35. doi: 10.1074/jbc.M112.342790. Epub 2012 Feb 23.


Intensity of deoxycytidine deamination of HIV-1 proviral DNA by the retroviral restriction factor APOBEC3G is mediated by the noncatalytic domain.

Feng Y, Chelico L.

J Biol Chem. 2011 Apr 1;286(13):11415-26. doi: 10.1074/jbc.M110.199604. Epub 2011 Feb 7.


Structural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3G.

Chelico L, Prochnow C, Erie DA, Chen XS, Goodman MF.

J Biol Chem. 2010 May 21;285(21):16195-205. doi: 10.1074/jbc.M110.107987. Epub 2010 Mar 8.


Biochemical basis of immunological and retroviral responses to DNA-targeted cytosine deamination by activation-induced cytidine deaminase and APOBEC3G.

Chelico L, Pham P, Petruska J, Goodman MF.

J Biol Chem. 2009 Oct 9;284(41):27761-5. doi: 10.1074/jbc.R109.052449. Epub 2009 Aug 13. Review.


Mechanisms of APOBEC3G-catalyzed processive deamination of deoxycytidine on single-stranded DNA.

Chelico L, Pham P, Goodman MF.

Nat Struct Mol Biol. 2009 May;16(5):454-5; author reply 455-6. doi: 10.1038/nsmb0509-454. No abstract available.


Dissecting APOBEC3G substrate specificity by nucleoside analog interference.

Rausch JW, Chelico L, Goodman MF, Le Grice SF.

J Biol Chem. 2009 Mar 13;284(11):7047-58. doi: 10.1074/jbc.M807258200. Epub 2009 Jan 9.


Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G.

Chelico L, Pham P, Goodman MF.

Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12;364(1517):583-93. doi: 10.1098/rstb.2008.0195. Review.


Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.

Holden LG, Prochnow C, Chang YP, Bransteitter R, Chelico L, Sen U, Stevens RC, Goodman MF, Chen XS.

Nature. 2008 Nov 6;456(7218):121-4. doi: 10.1038/nature07357. Epub 2008 Oct 12.


A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV.

Chelico L, Sacho EJ, Erie DA, Goodman MF.

J Biol Chem. 2008 May 16;283(20):13780-91. doi: 10.1074/jbc.M801004200. Epub 2008 Mar 24.


Isolation and characterization of nucleotide excision repair deficient mutants of the entomopathogenic fungus, Beauveria bassiana.

Chelico L, Khachatourians GG.

J Invertebr Pathol. 2008 May;98(1):93-100. Epub 2007 Oct 13.


DNA deaminases AID and APOBEC3G act processively on single-stranded DNA.

Pham P, Chelico L, Goodman MF.

DNA Repair (Amst). 2007 Jun 1;6(6):689-92; author reply 693-4. Epub 2007 Feb 8. No abstract available.


APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA.

Chelico L, Pham P, Calabrese P, Goodman MF.

Nat Struct Mol Biol. 2006 May;13(5):392-9. Epub 2006 Apr 23.


Quantification of ultraviolet-C irradiation induced cyclobutane pyrimidine dimers and their removal in Beauveria bassiana conidiospore DNA.

Chelico L, Haughian JL, Woytowich AE, Khachatourians GG.

Mycologia. 2005 May-Jun;97(3):621-7.


Permeabilization of Beauveria bassiana blastospores for in situ enzymatic assays.

Chelico L, Khachatourians GG.

Mycologia. 2003 Sep-Oct;95(5):976-81.


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