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Items: 1 to 50 of 58

1.

PAX5, NOTCH3, CBFB, and ACD drive an activated RAS pathway and monosomy 7 to B-ALL and AML in donor cell leukemia.

Assi R, Mahfouz R, Owen R, Gunthorpe M, Chehab FF, Bazarbachi A.

Bone Marrow Transplant. 2018 Dec 10. doi: 10.1038/s41409-018-0419-7. [Epub ahead of print] No abstract available.

PMID:
30532056
2.

Upregulation of cholesterol 24-hydroxylase following hypoxia-ischemia in neonatal mouse brain.

Lu F, Zhu J, Guo S, Wong BJ, Chehab FF, Ferriero DM, Jiang X.

Pediatr Res. 2018 Jun;83(6):1218-1227. doi: 10.1038/pr.2018.49. Epub 2018 May 2.

3.

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.

Stieglitz E, Mazor T, Olshen AB, Geng H, Gelston LC, Akutagawa J, Lipka DB, Plass C, Flotho C, Chehab FF, Braun BS, Costello JF, Loh ML.

Nat Commun. 2017 Dec 19;8(1):2127. doi: 10.1038/s41467-017-02178-9.

4.

First report of a deletion encompassing an entire exon in the homogentisate 1,2-dioxygenase gene causing alkaptonuria.

Zouheir Habbal M, Bou-Assi T, Zhu J, Owen R, Chehab FF.

PLoS One. 2014 Sep 18;9(9):e106948. doi: 10.1371/journal.pone.0106948. eCollection 2014.

5.

20 years of leptin: leptin and reproduction: past milestones, present undertakings, and future endeavors.

Chehab FF.

J Endocrinol. 2014 Oct;223(1):T37-48. doi: 10.1530/JOE-14-0413. Epub 2014 Aug 12. Review.

6.

FoxO4 interacts with the sterol regulatory factor SREBP2 and the hypoxia inducible factor HIF2α at the CYP51 promoter.

Zhu J, Jiang X, Chehab FF.

J Lipid Res. 2014 Mar;55(3):431-42. doi: 10.1194/jlr.M043521. Epub 2013 Dec 18.

7.

Duplication of C7orf58, WNT16 and FAM3C in an obese female with a t(7;22)(q32.1;q11.2) chromosomal translocation and clinical features resembling Coffin-Siris Syndrome.

Zhu J, Qiu J, Magrane G, Abedalthagafi M, Zanko A, Golabi M, Chehab FF.

PLoS One. 2012;7(12):e52353. doi: 10.1371/journal.pone.0052353. Epub 2012 Dec 27. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/c8463645-79f3-4d9b-bc55-d5d53e43a9ba.

8.

Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia.

Van Ziffle J, Yang W, Chehab FF.

PLoS One. 2011 Feb 24;6(2):e17327. doi: 10.1371/journal.pone.0017327.

9.

Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake.

Zhu J, Mounzih K, Chehab EF, Mitro N, Saez E, Chehab FF.

J Lipid Res. 2010 Jun;51(6):1312-24. doi: 10.1194/jlr.M001586. Epub 2009 Dec 25.

10.

Overexpression of the transcription factor Foxo4 is associated with rapid glucose clearance.

Wang B, Zhu J, Mounzih K, Chehab EF, Ke Y, Chehab FF.

Mol Cell Endocrinol. 2009 Aug 13;307(1-2):217-23. doi: 10.1016/j.mce.2009.04.011. Epub 2009 May 3.

PMID:
19410631
11.

Obesity and lipodystrophy--where do the circles intersect?

Chehab FF.

Endocrinology. 2008 Mar;149(3):925-34. doi: 10.1210/en.2007-1355. Epub 2008 Jan 17. Review.

12.
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The use of animal models to dissect the biology of leptin.

Chehab FF, Qiu J, Ogus S.

Recent Prog Horm Res. 2004;59:245-66. Review.

PMID:
14749505
15.

Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels.

Ke Y, Qiu J, Ogus S, Shen WJ, Kraemer FB, Chehab FF.

Biochem Biophys Res Commun. 2003 Dec 26;312(4):1165-70.

PMID:
14651995
16.

Hyperleptinemia precipitates diet-induced obesity in transgenic mice overexpressing leptin.

Ogus S, Ke Y, Qiu J, Wang B, Chehab FF.

Endocrinology. 2003 Jul;144(7):2865-9.

PMID:
12810541
17.

Leptin and reproduction.

Chehab FF, Qiu J, Mounzih K, Ewart-Toland A, Ogus S.

Nutr Rev. 2002 Oct;60(10 Pt 2):S39-46; discussion S68-84, 85-7. Review.

PMID:
12403083
18.
19.

Transgenic mice overexpressing leptin accumulate adipose mass at an older, but not younger, age.

Qiu J, Ogus S, Lu R, Chehab FF.

Endocrinology. 2001 Jan;142(1):348-58.

PMID:
11145598
20.

Leptin as a regulator of adipose mass and reproduction.

Chehab FF.

Trends Pharmacol Sci. 2000 Aug;21(8):309-14. Review.

PMID:
10918637
21.

Effect of the genetic background on the reproduction of leptin-deficient obese mice.

Ewart-Toland A, Mounzih K, Qiu J, Chehab FF.

Endocrinology. 1999 Feb;140(2):732-8.

PMID:
9927300
22.

Leptin is not necessary for gestation and parturition but regulates maternal nutrition via a leptin resistance state.

Mounzih K, Qiu J, Ewart-Toland A, Chehab FF.

Endocrinology. 1998 Dec;139(12):5259-62.

PMID:
9832467
23.

Cross-species characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene reveals multiple levels of regulation.

Vuillaumier S, Dixmeras I, Messaï H, Lapouméroulie C, Lallemand D, Gekas J, Chehab FF, Perret C, Elion J, Denamur E.

Biochem J. 1997 Nov 1;327 ( Pt 3):651-62.

24.

Is Hb A2 elevated in adults with sickle-alpha-thalassemia (beta(S)/beta(S); -alpha/-alpha)?

Ballas SK, Gay RN, Chehab FF.

Hemoglobin. 1997 Sep;21(5):405-50.

PMID:
9322076
25.

The reproductive side of leptin.

Chehab FF.

Nat Med. 1997 Sep;3(9):952-3. No abstract available.

PMID:
9288714
26.

Molecular basis of asymptomatic beta-thalassemia major in an African American individual.

Ballas SK, Cai SP, Gabuzda T, Chehab FF.

Am J Med Genet. 1997 Mar 17;69(2):196-9. Review.

PMID:
9056561
27.

Leptin treatment rescues the sterility of genetically obese ob/ob males.

Mounzih K, Lu R, Chehab FF.

Endocrinology. 1997 Mar;138(3):1190-3.

PMID:
9048626
28.

Early onset of reproductive function in normal female mice treated with leptin.

Chehab FF, Mounzih K, Lu R, Lim ME.

Science. 1997 Jan 3;275(5296):88-90.

29.

A broader role for leptin.

Chehab FF.

Nat Med. 1996 Jul;2(7):723-4. No abstract available.

PMID:
8673906
30.
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32.

Detection of viral deoxyribonucleic acid in the amniotic fluid of low-risk pregnancies by polymerase chain reaction.

McLean LK, Chehab FF, Goldberg JD.

Am J Obstet Gynecol. 1995 Oct;173(4):1282-6.

PMID:
7485338
33.

Methylation status of CpG sites in the mouse and human CFTR promoters.

Denamur E, Chehab FF.

DNA Cell Biol. 1995 Sep;14(9):811-5.

PMID:
7545404
34.
35.

Uniparental isodisomy for paternal 7p and maternal 7q in a child with growth retardation.

Eggerding FA, Schonberg SA, Chehab FF, Norton ME, Cox VA, Epstein CJ.

Am J Hum Genet. 1994 Aug;55(2):253-65.

36.

Analysis of the mouse and rat CFTR promoter regions.

Denamur E, Chehab FF.

Hum Mol Genet. 1994 Jul;3(7):1089-94.

PMID:
7526924
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39.

A new frameshift mutation, insertion of ATCT, at codon 48 in the beta-globin gene causes beta-thalassemia in an Indian proband.

Jain PK, Dozy AM, Verma IC, Chehab FF.

Hum Mutat. 1994;3(4):397-8. No abstract available.

PMID:
8081396
41.

Molecular diagnostics: past, present, and future.

Chehab FF.

Hum Mutat. 1993;2(5):331-7. Review.

PMID:
8257984
44.
46.

Detection of the hemoglobin E mutation using the color complementation assay: application to complex genotyping.

Embury SH, Kropp GL, Stanton TS, Warren TC, Cornett PA, Chehab FF.

Blood. 1990 Aug 1;76(3):619-23.

47.

Detection of sickle cell anaemia mutation by colour DNA amplification.

Chehab FF, Kan YW.

Lancet. 1990 Jan 6;335(8680):15-7.

PMID:
1967329
48.
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