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Items: 15


Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle.

Li X, Kumar S, McDew-White M, Haile M, Cheeseman IH, Emrich S, Button-Simons K, Nosten F, Kappe SHI, Ferdig MT, Anderson TJC, Vaughan AM.

PLoS Genet. 2019 Oct 14;15(10):e1008453. doi: 10.1371/journal.pgen.1008453. eCollection 2019 Oct.


Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates.

Tirrell AR, Vendrely KM, Checkley LA, Davis SZ, McDew-White M, Cheeseman IH, Vaughan AM, Nosten FH, Anderson TJC, Ferdig MT.

Malar J. 2019 Aug 28;18(1):295. doi: 10.1186/s12936-019-2934-4.


High-Resolution Single-Cell Sequencing of Malaria Parasites.

Trevino SG, Nkhoma SC, Nair S, Daniel BJ, Moncada K, Khoswe S, Banda RL, Nosten F, Cheeseman IH.

Genome Biol Evol. 2017 Dec 1;9(12):3373-3383. doi: 10.1093/gbe/evx256.


Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance.

Cerqueira GC, Cheeseman IH, Schaffner SF, Nair S, McDew-White M, Phyo AP, Ashley EA, Melnikov A, Rogov P, Birren BW, Nosten F, Anderson TJC, Neafsey DE.

Genome Biol. 2017 Apr 28;18(1):78. doi: 10.1186/s13059-017-1204-4.


Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites.

Anderson TJ, Nair S, McDew-White M, Cheeseman IH, Nkhoma S, Bilgic F, McGready R, Ashley E, Pyae Phyo A, White NJ, Nosten F.

Mol Biol Evol. 2017 Jan;34(1):131-144. doi: 10.1093/molbev/msw228. Epub 2016 Oct 20.


Population Structure Shapes Copy Number Variation in Malaria Parasites.

Cheeseman IH, Miller B, Tan JC, Tan A, Nair S, Nkhoma SC, De Donato M, Rodulfo H, Dondorp A, Branch OH, Mesia LR, Newton P, Mayxay M, Amambua-Ngwa A, Conway DJ, Nosten F, Ferdig MT, Anderson TJ.

Mol Biol Evol. 2016 Mar;33(3):603-20. doi: 10.1093/molbev/msv282. Epub 2015 Nov 26.


Plasmodium falciparum genetic crosses in a humanized mouse model.

Vaughan AM, Pinapati RS, Cheeseman IH, Camargo N, Fishbaugher M, Checkley LA, Nair S, Hutyra CA, Nosten FH, Anderson TJ, Ferdig MT, Kappe SH.

Nat Methods. 2015 Jul;12(7):631-3. doi: 10.1038/nmeth.3432. Epub 2015 Jun 1.


Pooled sequencing and rare variant association tests for identifying the determinants of emerging drug resistance in malaria parasites.

Cheeseman IH, McDew-White M, Phyo AP, Sriprawat K, Nosten F, Anderson TJ.

Mol Biol Evol. 2015 Apr;32(4):1080-90. doi: 10.1093/molbev/msu397. Epub 2014 Dec 21.


Single-cell genomics for dissection of complex malaria infections.

Nair S, Nkhoma SC, Serre D, Zimmerman PA, Gorena K, Daniel BJ, Nosten F, Anderson TJ, Cheeseman IH.

Genome Res. 2014 Jun;24(6):1028-38. doi: 10.1101/gr.168286.113. Epub 2014 May 8.


Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.

Amambua-Ngwa A, Tetteh KK, Manske M, Gomez-Escobar N, Stewart LB, Deerhake ME, Cheeseman IH, Newbold CI, Holder AA, Knuepfer E, Janha O, Jallow M, Campino S, Macinnis B, Kwiatkowski DP, Conway DJ.

PLoS Genet. 2012;8(11):e1002992. doi: 10.1371/journal.pgen.1002992. Epub 2012 Nov 1.


A major genome region underlying artemisinin resistance in malaria.

Cheeseman IH, Miller BA, Nair S, Nkhoma S, Tan A, Tan JC, Al Saai S, Phyo AP, Moo CL, Lwin KM, McGready R, Ashley E, Imwong M, Stepniewska K, Yi P, Dondorp AM, Mayxay M, Newton PN, White NJ, Nosten F, Ferdig MT, Anderson TJ.

Science. 2012 Apr 6;336(6077):79-82. doi: 10.1126/science.1215966.


Close kinship within multiple-genotype malaria parasite infections.

Nkhoma SC, Nair S, Cheeseman IH, Rohr-Allegrini C, Singlam S, Nosten F, Anderson TJ.

Proc Biol Sci. 2012 Jul 7;279(1738):2589-98. doi: 10.1098/rspb.2012.0113. Epub 2012 Mar 7.


An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations.

Tan JC, Miller BA, Tan A, Patel JJ, Cheeseman IH, Anderson TJ, Manske M, Maslen G, Kwiatkowski DP, Ferdig MT.

Genome Biol. 2011;12(4):R35. doi: 10.1186/gb-2011-12-4-r35. Epub 2011 Apr 8.


Gene copy number variation throughout the Plasmodium falciparum genome.

Cheeseman IH, Gomez-Escobar N, Carret CK, Ivens A, Stewart LB, Tetteh KK, Conway DJ.

BMC Genomics. 2009 Aug 4;10:353. doi: 10.1186/1471-2164-10-353.


Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria.

Walther M, Jeffries D, Finney OC, Njie M, Ebonyi A, Deininger S, Lawrence E, Ngwa-Amambua A, Jayasooriya S, Cheeseman IH, Gomez-Escobar N, Okebe J, Conway DJ, Riley EM.

PLoS Pathog. 2009 Apr;5(4):e1000364. doi: 10.1371/journal.ppat.1000364. Epub 2009 Apr 3.

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