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Items: 1 to 50 of 66

1.

CpxR/CpxA-controls scsABCD transcription to counteract copper and oxidative stress in Salmonella Typhimurium.

López C, Checa SK, Soncini FC.

J Bacteriol. 2018 Jun 4. pii: JB.00126-18. doi: 10.1128/JB.00126-18. [Epub ahead of print]

PMID:
29866803
2.

Sclerostin Neutralizing Antibody Treatment Enhances Bone Formation but Does Not Rescue Mechanically Induced Delayed Healing.

Kruck B, Zimmermann EA, Damerow S, Figge C, Julien C, Wulsten D, Thiele T, Martin M, Hamdy R, Reumann MK, Duda GN, Checa S, Willie BM.

J Bone Miner Res. 2018 Apr 25. doi: 10.1002/jbmr.3454. [Epub ahead of print]

PMID:
29694687
3.

Sost deficiency leads to reduced mechanical strains at the tibia midshaft in strain-matched in vivo loading experiments in mice.

Albiol L, Cilla M, Pflanz D, Kramer I, Kneissel M, Duda GN, Willie BM, Checa S.

J R Soc Interface. 2018 Apr;15(141). pii: 20180012. doi: 10.1098/rsif.2018.0012.

PMID:
29669893
4.

Physiological joint line total knee arthroplasty designs are especially sensitive to rotational placement - A finite element analysis.

Moewis P, Checa S, Kutzner I, Hommel H, Duda GN.

PLoS One. 2018 Feb 5;13(2):e0192225. doi: 10.1371/journal.pone.0192225. eCollection 2018.

5.

Mechanobiologically optimized 3D titanium-mesh scaffolds enhance bone regeneration in critical segmental defects in sheep.

Pobloth AM, Checa S, Razi H, Petersen A, Weaver JC, Schmidt-Bleek K, Windolf M, Tatai AÁ, Roth CP, Schaser KD, Duda GN, Schwabe P.

Sci Transl Med. 2018 Jan 10;10(423). pii: eaam8828. doi: 10.1126/scitranslmed.aam8828.

PMID:
29321260
6.

Examining tissue composition, whole-bone morphology and mechanical behavior of GorabPrx1 mice tibiae: A mouse model of premature aging.

Yang H, Albiol L, Chan WL, Wulsten D, Seliger A, Thelen M, Thiele T, Spevak L, Boskey A, Kornak U, Checa S, Willie BM.

J Biomech. 2017 Dec 8;65:145-153. doi: 10.1016/j.jbiomech.2017.10.018. Epub 2017 Oct 25.

PMID:
29108851
7.

Machine learning techniques for the optimization of joint replacements: Application to a short-stem hip implant.

Cilla M, Borgiani E, Martínez J, Duda GN, Checa S.

PLoS One. 2017 Sep 5;12(9):e0183755. doi: 10.1371/journal.pone.0183755. eCollection 2017.

8.

Sost deficiency led to a greater cortical bone formation response to mechanical loading and altered gene expression.

Pflanz D, Birkhold AI, Albiol L, Thiele T, Julien C, Seliger A, Thomson E, Kramer I, Kneissel M, Duda GN, Kornak U, Checa S, Willie BM.

Sci Rep. 2017 Aug 25;7(1):9435. doi: 10.1038/s41598-017-09653-9.

9.

Femoral head necrosis: A finite element analysis of common and novel surgical techniques.

Cilla M, Checa S, Preininger B, Winkler T, Perka C, Duda GN, Pumberger M.

Clin Biomech (Bristol, Avon). 2017 Oct;48:49-56. doi: 10.1016/j.clinbiomech.2017.07.005. Epub 2017 Jul 6.

PMID:
28728078
10.

The CpxR/CpxA system contributes to Salmonella gold-resistance by controlling the GolS-dependent gesABC transcription.

Cerminati S, Giri GF, Mendoza JI, Soncini FC, Checa SK.

Environ Microbiol. 2017 Oct;19(10):4035-4044. doi: 10.1111/1462-2920.13837. Epub 2017 Jul 17.

PMID:
28631419
11.

Multiscale Modeling of Bone Healing: Toward a Systems Biology Approach.

Borgiani E, Duda GN, Checa S.

Front Physiol. 2017 May 8;8:287. doi: 10.3389/fphys.2017.00287. eCollection 2017. Review.

12.

Strain shielding inspired re-design of proximal femoral stems for total hip arthroplasty.

Cilla M, Checa S, Duda GN.

J Orthop Res. 2017 Nov;35(11):2534-2544. doi: 10.1002/jor.23540. Epub 2017 Mar 2.

PMID:
28176355
13.

Tomography-Based Quantification of Regional Differences in Cortical Bone Surface Remodeling and Mechano-Response.

Birkhold AI, Razi H, Duda GN, Checa S, Willie BM.

Calcif Tissue Int. 2017 Mar;100(3):255-270. doi: 10.1007/s00223-016-0217-4. Epub 2016 Dec 20.

PMID:
27999894
14.

The Periosteal Bone Surface is Less Mechano-Responsive than the Endocortical.

Birkhold AI, Razi H, Duda GN, Weinkamer R, Checa S, Willie BM.

Sci Rep. 2016 Mar 23;6:23480. doi: 10.1038/srep23480.

15.

Computational analyses of different intervertebral cages for lumbar spinal fusion.

Bashkuev M, Checa S, Postigo S, Duda G, Schmidt H.

J Biomech. 2015 Sep 18;48(12):3274-82. doi: 10.1016/j.jbiomech.2015.06.024. Epub 2015 Jun 30.

PMID:
26162547
16.

Skeletal maturation substantially affects elastic tissue properties in the endosteal and periosteal regions of loaded mice tibiae.

Checa S, Hesse B, Roschger P, Aido M, Duda GN, Raum K, Willie BM.

Acta Biomater. 2015 Jul;21:154-64. doi: 10.1016/j.actbio.2015.04.020. Epub 2015 Apr 18.

PMID:
25900443
17.

Aging Leads to a Dysregulation in Mechanically Driven Bone Formation and Resorption.

Razi H, Birkhold AI, Weinkamer R, Duda GN, Willie BM, Checa S.

J Bone Miner Res. 2015 Oct;30(10):1864-73. doi: 10.1002/jbmr.2528. Epub 2015 May 1.

18.

Monitoring in vivo (re)modeling: a computational approach using 4D microCT data to quantify bone surface movements.

Birkhold AI, Razi H, Weinkamer R, Duda GN, Checa S, Willie BM.

Bone. 2015 Jun;75:210-21. doi: 10.1016/j.bone.2015.02.027. Epub 2015 Mar 4.

PMID:
25746796
19.

A sensitive whole-cell biosensor for the simultaneous detection of a broad-spectrum of toxic heavy metal ions.

Cerminati S, Soncini FC, Checa SK.

Chem Commun (Camb). 2015 Apr 7;51(27):5917-20. doi: 10.1039/c5cc00981b. Epub 2015 Mar 2.

PMID:
25730473
20.

A single serine residue determines selectivity to monovalent metal ions in metalloregulators of the MerR family.

Ibáñez MM, Checa SK, Soncini FC.

J Bacteriol. 2015 May;197(9):1606-13. doi: 10.1128/JB.02565-14. Epub 2015 Feb 17.

21.

Effect of in vivo loading on bone composition varies with animal age.

Aido M, Kerschnitzki M, Hoerth R, Checa S, Spevak L, Boskey AL, Fratzl P, Duda GN, Wagermaier W, Willie BM.

Exp Gerontol. 2015 Mar;63:48-58. doi: 10.1016/j.exger.2015.01.048. Epub 2015 Jan 30.

22.

Skeletal maturity leads to a reduction in the strain magnitudes induced within the bone: a murine tibia study.

Razi H, Birkhold AI, Zaslansky P, Weinkamer R, Duda GN, Willie BM, Checa S.

Acta Biomater. 2015 Feb;13:301-10. doi: 10.1016/j.actbio.2014.11.021. Epub 2014 Nov 20.

PMID:
25463494
23.

Relationship between nanoscale mineral properties and calcein labeling in mineralizing bone surfaces.

Aido M, Kerschnitzki M, Hoerth R, Burghammer M, Montero C, Checa S, Fratzl P, Duda GN, Willie BM, Wagermaier W.

Connect Tissue Res. 2014 Aug;55 Suppl 1:15-7. doi: 10.3109/03008207.2014.923869.

PMID:
25158172
24.

The influence of age on adaptive bone formation and bone resorption.

Birkhold AI, Razi H, Duda GN, Weinkamer R, Checa S, Willie BM.

Biomaterials. 2014 Nov;35(34):9290-301. doi: 10.1016/j.biomaterials.2014.07.051. Epub 2014 Aug 13.

PMID:
25128376
25.

Mineralizing surface is the main target of mechanical stimulation independent of age: 3D dynamic in vivo morphometry.

Birkhold AI, Razi H, Duda GN, Weinkamer R, Checa S, Willie BM.

Bone. 2014 Sep;66:15-25. doi: 10.1016/j.bone.2014.05.013. Epub 2014 Jun 2.

PMID:
24882735
26.

Identification of a Salmonella ancillary copper detoxification mechanism by a comparative analysis of the genome-wide transcriptional response to copper and zinc excess.

Pontel LB, Scampoli NL, Porwollik S, Checa SK, McClelland M, Soncini FC.

Microbiology. 2014 Aug;160(Pt 8):1659-1669. doi: 10.1099/mic.0.080473-0. Epub 2014 May 23.

27.

The emergence of extracellular matrix mechanics and cell traction forces as important regulators of cellular self-organization.

Checa S, Rausch MK, Petersen A, Kuhl E, Duda GN.

Biomech Model Mechanobiol. 2015 Jan;14(1):1-13. doi: 10.1007/s10237-014-0581-9. Epub 2014 Apr 10.

PMID:
24718853
28.

Investigation of different cage designs and mechano-regulation algorithms in the lumbar interbody fusion process - a finite element analysis.

Postigo S, Schmidt H, Rohlmann A, Putzier M, Simón A, Duda G, Checa S.

J Biomech. 2014 Apr 11;47(6):1514-9. doi: 10.1016/j.jbiomech.2014.02.005. Epub 2014 Feb 15.

PMID:
24607006
29.

Protein signatures that promote operator selectivity among paralog MerR monovalent metal ion regulators.

Humbert MV, Rasia RM, Checa SK, Soncini FC.

J Biol Chem. 2013 Jul 12;288(28):20510-9. doi: 10.1074/jbc.M113.452797. Epub 2013 Jun 3.

30.

Dissecting the metal selectivity of MerR monovalent metal ion sensors in Salmonella.

Ibáñez MM, Cerminati S, Checa SK, Soncini FC.

J Bacteriol. 2013 Jul;195(13):3084-92. doi: 10.1128/JB.00153-13. Epub 2013 May 3.

31.

Diminished response to in vivo mechanical loading in trabecular and not cortical bone in adulthood of female C57Bl/6 mice coincides with a reduction in deformation to load.

Willie BM, Birkhold AI, Razi H, Thiele T, Aido M, Kruck B, Schill A, Checa S, Main RP, Duda GN.

Bone. 2013 Aug;55(2):335-46. doi: 10.1016/j.bone.2013.04.023. Epub 2013 May 1.

PMID:
23643681
32.

In vivo tracking of segmental bone defect healing reveals that callus patterning is related to early mechanical stimuli.

Mehta M, Checa S, Lienau J, Hutmacher D, Duda GN.

Eur Cell Mater. 2012 Nov 2;24:358-71; discussion 371.

33.

Shaping scaffold structures in rapid manufacturing implants: a modeling approach toward mechano-biologically optimized configurations for large bone defect.

Razi H, Checa S, Schaser KD, Duda GN.

J Biomed Mater Res B Appl Biomater. 2012 Oct;100(7):1736-45. doi: 10.1002/jbm.b.32740. Epub 2012 Jul 18.

PMID:
22807248
34.

Bacterial signaling systems as platforms for rational design of new generations of biosensors.

Checa SK, Zurbriggen MD, Soncini FC.

Curr Opin Biotechnol. 2012 Oct;23(5):766-72. doi: 10.1016/j.copbio.2012.05.003. Epub 2012 Jun 2. Review.

PMID:
22658939
35.

Selective detection of gold using genetically engineered bacterial reporters.

Cerminati S, Soncini FC, Checa SK.

Biotechnol Bioeng. 2011 Nov;108(11):2553-60. doi: 10.1002/bit.23213. Epub 2011 Jun 9.

PMID:
21618467
36.

Inter-species investigation of the mechano-regulation of bone healing: comparison of secondary bone healing in sheep and rat.

Checa S, Prendergast PJ, Duda GN.

J Biomech. 2011 Apr 29;44(7):1237-45. doi: 10.1016/j.jbiomech.2011.02.074. Epub 2011 Mar 17.

PMID:
21419412
37.

Variability observed in mechano-regulated in vivo tissue differentiation can be explained by variation in cell mechano-sensitivity.

Khayyeri H, Checa S, Tägil M, Aspenberg P, Prendergast PJ.

J Biomech. 2011 Apr 7;44(6):1051-8. doi: 10.1016/j.jbiomech.2011.02.003. Epub 2011 Mar 5.

PMID:
21377680
38.

Spatial-temporal mapping of bone structural and elastic properties in a sheep model following osteotomy.

Preininger B, Checa S, Molnar FL, Fratzl P, Duda GN, Raum K.

Ultrasound Med Biol. 2011 Mar;37(3):474-83. doi: 10.1016/j.ultrasmedbio.2010.12.007. Epub 2011 Jan 21.

PMID:
21256668
39.

Bacterial gold sensing and resistance.

Checa SK, Soncini FC.

Biometals. 2011 Jun;24(3):419-27. doi: 10.1007/s10534-010-9393-2. Epub 2010 Dec 14. Review.

PMID:
21153861
40.

Target transcription binding sites differentiate two groups of MerR-monovalent metal ion sensors.

Pérez Audero ME, Podoroska BM, Ibáñez MM, Cauerhff A, Checa SK, Soncini FC.

Mol Microbiol. 2010 Nov;78(4):853-65. doi: 10.1111/j.1365-2958.2010.07370.x. Epub 2010 Sep 24.

41.

Tissue differentiation in an in vivo bioreactor: in silico investigations of scaffold stiffness.

Khayyeri H, Checa S, Tägil M, O'Brien FJ, Prendergast PJ.

J Mater Sci Mater Med. 2010 Aug;21(8):2331-6. doi: 10.1007/s10856-009-3973-0.

PMID:
20037774
42.

Simulation of angiogenesis and cell differentiation in a CaP scaffold subjected to compressive strains using a lattice modeling approach.

Sandino C, Checa S, Prendergast PJ, Lacroix D.

Biomaterials. 2010 Mar;31(8):2446-52. doi: 10.1016/j.biomaterials.2009.11.063. Epub 2009 Dec 6.

PMID:
19969348
43.
44.

Corroboration of mechanobiological simulations of tissue differentiation in an in vivo bone chamber using a lattice-modeling approach.

Khayyeri H, Checa S, Tägil M, Prendergast PJ.

J Orthop Res. 2009 Dec;27(12):1659-66. doi: 10.1002/jor.20926.

45.

Characterization of Citrus sinensis type 1 mitochondrial alternative oxidase and expression analysis in biotic stress.

Daurelio LD, Checa SK, Barrio JM, Ottado J, Orellano EG.

Biosci Rep. 2009 Oct 9;30(1):59-71, 1 p following 71. doi: 10.1042/BSR20080180.

PMID:
19257856
46.

Downregulation of RpoN-controlled genes protects Salmonella cells from killing by the cationic antimicrobial peptide polymyxin B.

Barchiesi J, Espariz M, Checa SK, Soncini FC.

FEMS Microbiol Lett. 2009 Feb;291(1):73-9. doi: 10.1111/j.1574-6968.2008.01437.x. Epub 2008 Dec 3.

47.

A mechanobiological model for tissue differentiation that includes angiogenesis: a lattice-based modeling approach.

Checa S, Prendergast PJ.

Ann Biomed Eng. 2009 Jan;37(1):129-45. doi: 10.1007/s10439-008-9594-9. Epub 2008 Nov 15.

PMID:
19011968
48.

Influence of an interpositional spacer on the behaviour of the tibiofemoral joint: a finite element study.

Checa S, Taylor M, New A.

Clin Biomech (Bristol, Avon). 2008 Oct;23(8):1044-52. doi: 10.1016/j.clinbiomech.2008.04.006. Epub 2008 May 21.

PMID:
18499317
49.

GolS controls the response to gold by the hierarchical induction of Salmonella-specific genes that include a CBA efflux-coding operon.

Pontel LB, Audero ME, Espariz M, Checa SK, Soncini FC.

Mol Microbiol. 2007 Nov;66(3):814-25. Epub 2007 Oct 4.

50.

Dissecting the Salmonella response to copper.

Espariz M, Checa SK, Audero ME, Pontel LB, Soncini FC.

Microbiology. 2007 Sep;153(Pt 9):2989-97.

PMID:
17768242

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