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Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study.

Sjödin MOD, Checa A, Yang M, Dahlén SE, Wheelock ÅM, Eklund A, Grunewald J, Wheelock CE.

Respir Res. 2018 Dec 3;19(1):236. doi: 10.1186/s12931-018-0939-0.


The influence of culture media upon observed cell secretome metabolite profiles: The balance between cell viability and data interpretability.

Daskalaki E, Pillon NJ, Krook A, Wheelock CE, Checa A.

Anal Chim Acta. 2018 Dec 11;1037:338-350. doi: 10.1016/j.aca.2018.04.034. Epub 2018 Apr 18.


Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose-lowering therapy.

Mahdi A, Kövamees O, Checa A, Wheelock CE, von Heijne M, Alvarsson M, Pernow J.

J Intern Med. 2018 Oct;284(4):388-398. doi: 10.1111/joim.12785. Epub 2018 Aug 27.


ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages.

Laguna-Fernandez A, Checa A, Carracedo M, Artiach G, Petri MH, Baumgartner R, Forteza MJ, Jiang X, Andonova T, Walker ME, Dalli J, Arnardottir H, Gisterå A, Thul S, Wheelock CE, Paulsson-Berne G, Ketelhuth DFJ, Hansson GK, Bäck M.

Circulation. 2018 Oct 16;138(16):1693-1705. doi: 10.1161/CIRCULATIONAHA.117.032801.


Cerebrospinal fluid levels of sphingolipids associate with disease severity in first episode psychosis patients.

Checa A, Malmqvist A, Flyckt L, Schwieler L, Samuelsson M, Skogh E, Cervenka S, Dahl ML, Piehl F; Karolinska Schizophrenia Project (KaSP) Consortium, Erhardt S, Wheelock CE.

Schizophr Res. 2018 Sep;199:438-441. doi: 10.1016/j.schres.2018.03.029. Epub 2018 Apr 4. No abstract available.


Increased Levels of Circulating Fatty Acids Are Associated with Protective Effects against Future Cardiovascular Events in Nondiabetics.

Kamleh MA, McLeod O, Checa A, Baldassarre D, Veglia F, Gertow K, Humphries SE, Rauramaa R, de Faire U, Smit AJ, Giral P, Kurl S, Mannarino E, Tremoli E, Silveira A, Örvik J, Hamsten A, Wheelock CE.

J Proteome Res. 2018 Feb 2;17(2):870-878. doi: 10.1021/acs.jproteome.7b00671. Epub 2018 Jan 22.


Changes in arterial pressure and markers of nitric oxide homeostasis and oxidative stress following surgical correction of hydronephrosis in children.

Al-Mashhadi A, Checa A, Wåhlin N, Neveus T, Fossum M, Wheelock CE, Karanikas B, Stenberg A, Persson AEG, Carlstrom M.

Pediatr Nephrol. 2018 Apr;33(4):639-649. doi: 10.1007/s00467-017-3848-4. Epub 2017 Dec 1.


Adipocyte Expression of SLC19A1 Links DNA Hypermethylation to Adipose Tissue Inflammation and Insulin Resistance.

Petrus P, Bialesova L, Checa A, Kerr A, Naz S, Bäckdahl J, Gracia A, Toft S, Dahlman-Wright K, Hedén P, Dahlman I, Wheelock CE, Arner P, Mejhert N, Gao H, Rydén M.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):710-721. doi: 10.1210/jc.2017-01382.


Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

Bowden JA, Heckert A, Ulmer CZ, Jones CM, Koelmel JP, Abdullah L, Ahonen L, Alnouti Y, Armando AM, Asara JM, Bamba T, Barr JR, Bergquist J, Borchers CH, Brandsma J, Breitkopf SB, Cajka T, Cazenave-Gassiot A, Checa A, Cinel MA, Colas RA, Cremers S, Dennis EA, Evans JE, Fauland A, Fiehn O, Gardner MS, Garrett TJ, Gotlinger KH, Han J, Huang Y, Neo AH, Hyötyläinen T, Izumi Y, Jiang H, Jiang H, Jiang J, Kachman M, Kiyonami R, Klavins K, Klose C, Köfeler HC, Kolmert J, Koal T, Koster G, Kuklenyik Z, Kurland IJ, Leadley M, Lin K, Maddipati KR, McDougall D, Meikle PJ, Mellett NA, Monnin C, Moseley MA, Nandakumar R, Oresic M, Patterson R, Peake D, Pierce JS, Post M, Postle AD, Pugh R, Qiu Y, Quehenberger O, Ramrup P, Rees J, Rembiesa B, Reynaud D, Roth MR, Sales S, Schuhmann K, Schwartzman ML, Serhan CN, Shevchenko A, Somerville SE, St John-Williams L, Surma MA, Takeda H, Thakare R, Thompson JW, Torta F, Triebl A, Trötzmüller M, Ubhayasekera SJK, Vuckovic D, Weir JM, Welti R, Wenk MR, Wheelock CE, Yao L, Yuan M, Zhao XH, Zhou S.

J Lipid Res. 2017 Dec;58(12):2275-2288. doi: 10.1194/jlr.M079012. Epub 2017 Oct 6.


Transformation of ACC into aragonite and the origin of the nanogranular structure of nacre.

Macías-Sánchez E, Willinger MG, Pina CM, Checa AG.

Sci Rep. 2017 Oct 5;7(1):12728. doi: 10.1038/s41598-017-12673-0.


Physical versus Biological Control in Bivalve Calcite Prisms: Comparison of Euheterodonts and Pteriomorphs.

Harper EM, Checa A.

Biol Bull. 2017 Feb;232(1):19-29. doi: 10.1086/691382. Epub 2017 Mar 27. Erratum in: Biol Bull. 2017 Jun;232(3):222.


Metabolomics analysis identifies different metabotypes of asthma severity.

Reinke SN, Gallart-Ayala H, Gómez C, Checa A, Fauland A, Naz S, Kamleh MA, Djukanović R, Hinks TS, Wheelock CE.

Eur Respir J. 2017 Mar 29;49(3). pii: 1601740. doi: 10.1183/13993003.01740-2016. Print 2017 Mar.


Dysregulations in circulating sphingolipids associate with disease activity indices in female patients with systemic lupus erythematosus: a cross-sectional study.

Checa A, Idborg H, Zandian A, Sar DG, Surowiec I, Trygg J, Svenungsson E, Jakobsson PJ, Nilsson P, Gunnarsson I, Wheelock CE.

Lupus. 2017 Sep;26(10):1023-1033. doi: 10.1177/0961203316686707. Epub 2017 Jan 29.


New insights into the effects of onion consumption on lipid mediators using a diet-induced model of hypercholesterolemia.

González-Peña D, Checa A, de Ancos B, Wheelock CE, Sánchez-Moreno C.

Redox Biol. 2017 Apr;11:205-212. doi: 10.1016/j.redox.2016.12.002. Epub 2016 Dec 9.


The present scope of Biomineralization.

Cartwright JH, Checa AG, Sainz-Díaz CI.

J Struct Biol. 2016 Nov;196(2):65-66. doi: 10.1016/j.jsb.2016.10.009. No abstract available.


Arginase Inhibition Improves Microvascular Endothelial Function in Patients With Type 2 Diabetes Mellitus.

Kövamees O, Shemyakin A, Checa A, Wheelock CE, Lundberg JO, Östenson CG, Pernow J.

J Clin Endocrinol Metab. 2016 Nov;101(11):3952-3958. Epub 2016 Jul 11.


Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation.

Hezel M, Peleli M, Liu M, Zollbrecht C, Jensen BL, Checa A, Giulietti A, Wheelock CE, Lundberg JO, Weitzberg E, Carlström M.

Free Radic Biol Med. 2016 Oct;99:87-98. doi: 10.1016/j.freeradbiomed.2016.07.025. Epub 2016 Jul 26.


Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion.

Paquin-Proulx D, Gibbs A, Bächle SM, Checa A, Introini A, Leeansyah E, Wheelock CE, Nixon DF, Broliden K, Tjernlund A, Moll M, Sandberg JK.

J Immunol. 2016 Sep 1;197(5):1843-51. doi: 10.4049/jimmunol.1600556. Epub 2016 Aug 1.


Region 4 of Rhizobium etli Primary Sigma Factor (SigA) Confers Transcriptional Laxity in Escherichia coli.

Santillán O, Ramírez-Romero MA, Lozano L, Checa A, Encarnación SM, Dávila G.

Front Microbiol. 2016 Jul 13;7:1078. doi: 10.3389/fmicb.2016.01078. eCollection 2016.


Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension.

Yang T, Zollbrecht C, Winerdal ME, Zhuge Z, Zhang XM, Terrando N, Checa A, Sällström J, Wheelock CE, Winqvist O, Harris RA, Larsson E, Persson AE, Fredholm BB, Carlström M.

J Am Heart Assoc. 2016 Jul 18;5(7). pii: e003868. doi: 10.1161/JAHA.116.003868.


Fluid-flow-templated self-assembly of calcium carbonate tubes in the laboratory and in biomineralization: The tubules of the watering-pot shells, Clavagelloidea.

Cardoso SSS, Cartwright JHE, Checa AG, Sainz-Díaz CI.

Acta Biomater. 2016 Oct 1;43:338-347. doi: 10.1016/j.actbio.2016.07.005. Epub 2016 Jul 9.


Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia.

Carlström M, Cananau C, Checa A, Wide K, Sartz L, Svensson A, Wheelock CE, Westphal S, Békássy Z, Bárány P, Lundberg JO, Hansson S, Weitzberg E, Krmar RT.

Nitric Oxide. 2016 Aug 31;58:1-9. doi: 10.1016/j.niox.2016.05.005. Epub 2016 May 24.


Biological strategy for the fabrication of highly ordered aragonite helices: the microstructure of the cavolinioidean gastropods.

Checa AG, Macías-Sánchez E, Ramírez-Rico J.

Sci Rep. 2016 May 16;6:25989. doi: 10.1038/srep25989.


Organic membranes determine the pattern of the columnar prismatic layer of mollusc shells.

Checa AG, Macías-Sánchez E, Harper EM, Cartwright JH.

Proc Biol Sci. 2016 May 11;283(1830). pii: 20160032. doi: 10.1098/rspb.2016.0032.


Told through the wine: A liquid chromatography-mass spectrometry interplatform comparison reveals the influence of the global approach on the final annotated metabolites in non-targeted metabolomics.

Díaz R, Gallart-Ayala H, Sancho JV, Nuñez O, Zamora T, Martins CP, Hernández F, Hernández-Cassou S, Saurina J, Checa A.

J Chromatogr A. 2016 Feb 12;1433:90-7. doi: 10.1016/j.chroma.2016.01.010. Epub 2016 Jan 7.


Irregularities of crystallographic orientation and residual stresses in the crossed-lamellar shell as a natural functionally graded material.

Bonarski JT, Checa AG, Rodriguez-Navarro A, Tarkowski L, Wajda W.

J R Soc Interface. 2015 Dec 6;12(113):20150738. doi: 10.1098/rsif.2015.0738.


Lipid mediator profile in vernix caseosa reflects skin barrier development.

Checa A, Holm T, Sjödin MO, Reinke SN, Alm J, Scheynius A, Wheelock CE.

Sci Rep. 2015 Nov 2;5:15740. doi: 10.1038/srep15740.


Lipidomic data analysis: tutorial, practical guidelines and applications.

Checa A, Bedia C, Jaumot J.

Anal Chim Acta. 2015 Jul 23;885:1-16. doi: 10.1016/j.aca.2015.02.068. Epub 2015 Mar 12. Review.


Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment.

Checa A, Xu N, Sar DG, Haeggström JZ, Ståhle M, Wheelock CE.

Sci Rep. 2015 Jul 15;5:12017. doi: 10.1038/srep12017.


The cuttlefish Sepia officinalis (Sepiidae, Cephalopoda) constructs cuttlebone from a liquid-crystal precursor.

Checa AG, Cartwright JH, Sánchez-Almazo I, Andrade JP, Ruiz-Raya F.

Sci Rep. 2015 Jun 18;5:11513. doi: 10.1038/srep11513.


Effects of long-term dietary nitrate supplementation in mice.

Hezel MP, Liu M, Schiffer TA, Larsen FJ, Checa A, Wheelock CE, Carlström M, Lundberg JO, Weitzberg E.

Redox Biol. 2015 Aug;5:234-42. doi: 10.1016/j.redox.2015.05.004. Epub 2015 May 29.


Ultrastructure of the Interlamellar Membranes of the Nacre of the Bivalve Pteria hirundo, Determined by Immunolabelling.

Osuna-Mascaró AJ, Cruz-Bustos T, Marin F, Checa AG.

PLoS One. 2015 Apr 24;10(4):e0122934. doi: 10.1371/journal.pone.0122934. eCollection 2015.


Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis.

Checa A, Khademi M, Sar DG, Haeggström JZ, Lundberg JO, Piehl F, Olsson T, Wheelock CE.

Mult Scler. 2015 Sep;21(10):1271-9. doi: 10.1177/1352458514561908. Epub 2014 Dec 5.


Rates of meniscal tearing in patients with chondrocalcinosis.

Checa A, Chun W.

Clin Rheumatol. 2015 Mar;34(3):573-7. doi: 10.1007/s10067-014-2797-6. Epub 2014 Nov 29.


Sonographic assessment of the carpal tunnel syndrome secondary to a tenosynovitis of the flexor digitorum superficialis in a patient with rheumatoid arthritis.

Panahi E, O'Connor CR, Checa A.

J Clin Rheumatol. 2014 Aug;20(5):294-5. doi: 10.1097/RHU.0000000000000131. No abstract available.


Clinical images: Is ultrasonography better than radiography for determining the need for surgical treatment in patients with carpometacarpal osteoarthritis?

Checa A, Panahi E.

Arthritis Rheumatol. 2014 Jul;66(7):1954. doi: 10.1002/art.38619. No abstract available.


Early stage biomineralization in the periostracum of the 'living fossil' bivalve Neotrigonia.

Checa AG, Salas C, Harper EM, Bueno-Pérez Jde D.

PLoS One. 2014 Feb 25;9(2):e90033. doi: 10.1371/journal.pone.0090033. eCollection 2014.


Sonographic evidence of impingement mechanism in a patient with patellar tendon rupture after total knee replacement.

Checa A, O'Connor CR.

Int J Rheum Dis. 2014 Feb;17(2):221-2. doi: 10.1111/1756-185X.12077. Epub 2013 May 23. No abstract available.


Sonographic bulge test for small effusion and occult synovitis of the knee.

Checa A, Hussain H.

J Clin Rheumatol. 2014 Mar;20(2):109-11. doi: 10.1097/RHU.0000000000000075. No abstract available.


Dietary nitrate reduces resting metabolic rate: a randomized, crossover study in humans.

Larsen FJ, Schiffer TA, Ekblom B, Mattsson MP, Checa A, Wheelock CE, Nyström T, Lundberg JO, Weitzberg E.

Am J Clin Nutr. 2014 Apr;99(4):843-50. doi: 10.3945/ajcn.113.079491. Epub 2014 Feb 5.


Painless engorgement of the calf in a patient with ankylosing spondylitis.

Checa A, Zarro VJ.

Int J Rheum Dis. 2014 Feb;17(2):210-1. doi: 10.1111/1756-185X.12231. Epub 2013 Dec 16. No abstract available.


The shell organic matrix of the crossed lamellar queen conch shell (Strombus gigas).

Osuna-Mascaró A, Cruz-Bustos T, Benhamada S, Guichard N, Marie B, Plasseraud L, Corneillat M, Alcaraz G, Checa A, Marin F.

Comp Biochem Physiol B Biochem Mol Biol. 2014 Feb;168:76-85. doi: 10.1016/j.cbpb.2013.11.009. Epub 2013 Nov 28.


Crystallographic control on the substructure of nacre tablets.

Checa AG, Mutvei H, Osuna-Mascaró AJ, Bonarski JT, Faryna M, Berent K, Pina CM, Rousseau M, Macías-Sánchez E.

J Struct Biol. 2013 Sep;183(3):368-376. doi: 10.1016/j.jsb.2013.07.014. Epub 2013 Aug 6.


Quantitative metabolic profiling of lipid mediators.

Balgoma D, Checa A, Sar DG, Snowden S, Wheelock CE.

Mol Nutr Food Res. 2013 Aug;57(8):1359-77. doi: 10.1002/mnfr.201200840. Epub 2013 Jul 4. Review.


Crystallographic orientation inhomogeneity and crystal splitting in biogenic calcite.

Checa AG, Bonarski JT, Willinger MG, Faryna M, Berent K, Kania B, González-Segura A, Pina CM, Pospiech J, Morawiec A.

J R Soc Interface. 2013 Jun 26;10(86):20130425. doi: 10.1098/rsif.2013.0425. Print 2013 Sep 6.


Pearls are self-organized natural ratchets.

Cartwright JH, Checa AG, Rousseau M.

Langmuir. 2013 Jul 2;29(26):8370-6. doi: 10.1021/la4014202. Epub 2013 Jun 18.


Persistent median artery in the wrist: from a medical curiosity to a common anatomic variant with therapeutic implications.

Checa A, Manohar J, Russell E, Hussain H.

J Clin Rheumatol. 2013 Jun;19(4):223-4. doi: 10.1097/RHU.0b013e318293ae64. No abstract available.


Potential pitfalls in the diagnosis of crystal-induced arthritis and in the sonographic measurement of hyaline cartilage due to the presence of joint effusion.

Russell E, Checa A.

J Clin Rheumatol. 2013 Mar;19(2):98-100. doi: 10.1097/RHU.0b013e31828635c5. No abstract available.


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