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Items: 1 to 50 of 91

1.

Comprehensive literature data-mining analysis reveals a broad genetic network functionally associated with autism spectrum disorder.

Xu C, Cao H, Zhang F, Cheadle C.

Int J Mol Med. 2018 Nov;42(5):2353-2362. doi: 10.3892/ijmm.2018.3845. Epub 2018 Aug 28.

PMID:
30226572
2.

Shortwave infrared luminescent Pt-nanowires: a mechanistic study of emission in solution and in the solid state.

Cheadle C, Ratcliff J, Berezin M, Pal'shin V, Nemykin VN, Gerasimchuk NN.

Dalton Trans. 2017 Oct 10;46(39):13562-13581. doi: 10.1039/c7dt02317k.

3.

Advanced literature analysis in a Big Data world.

Cheadle C, Cao H, Kalinin A, Hodgkinson J.

Ann N Y Acad Sci. 2017 Jan;1387(1):25-33. doi: 10.1111/nyas.13270. Epub 2016 Nov 10. Review.

PMID:
27859320
4.

The Intratumoral Balance between Metabolic and Immunologic Gene Expression Is Associated with Anti-PD-1 Response in Patients with Renal Cell Carcinoma.

Ascierto ML, McMiller TL, Berger AE, Danilova L, Anders RA, Netto GJ, Xu H, Pritchard TS, Fan J, Cheadle C, Cope L, Drake CG, Pardoll DM, Taube JM, Topalian SL.

Cancer Immunol Res. 2016 Sep 2;4(9):726-33. doi: 10.1158/2326-6066.CIR-16-0072. Epub 2016 Aug 4.

5.

Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APCMin/+ Mouse Model of Intestinal Tumorigenesis.

Paul-Clark M, Elsheikh W, Kirkby N, Chan M, Devchand P, Agbor TA, Flannigan KL, Cheadle C, Freydin M, Ianaro A, Mitchell JA, Wallace JL.

PLoS One. 2016 Feb 24;11(2):e0147289. doi: 10.1371/journal.pone.0147289. eCollection 2016.

6.

Longitudinal Transcriptome Analysis Reveals a Sustained Differential Gene Expression Signature in Patients Treated for Acute Lyme Disease.

Bouquet J, Soloski MJ, Swei A, Cheadle C, Federman S, Billaud JN, Rebman AW, Kabre B, Halpert R, Boorgula M, Aucott JN, Chiu CY.

MBio. 2016 Feb 12;7(1):e00100-16. doi: 10.1128/mBio.00100-16.

7.

Identification of Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis by Whole-Exome Sequencing.

Gao L, Emond MJ, Louie T, Cheadle C, Berger AE, Rafaels N, Vergara C, Kim Y, Taub MA, Ruczinski I, Mathai SC, Rich SS, Nickerson DA, Hummers LK, Bamshad MJ, Hassoun PM, Mathias RA; National Heart, Lung, and Blood Institute GO Exome Sequencing Project, Barnes KC.

Arthritis Rheumatol. 2016 Jan;68(1):191-200. doi: 10.1002/art.39449.

8.

Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data.

Ma J, Chen C, Barth AS, Cheadle C, Guan X, Gao L.

Mediators Inflamm. 2015;2015:984825. doi: 10.1155/2015/984825. Epub 2015 Apr 30. Review.

9.

Mobilization of epithelial mesenchymal transition genes distinguishes active from inactive lesional tissue in patients with ulcerative colitis.

Zhao X, Fan J, Zhi F, Li A, Li C, Berger AE, Boorgula MP, Barkataki S, Courneya JP, Chen Y, Barnes KC, Cheadle C.

Hum Mol Genet. 2015 Aug 15;24(16):4615-24. doi: 10.1093/hmg/ddv192. Epub 2015 Jun 1.

PMID:
26034135
10.

Differential Expression of Immune-Regulatory Genes Associated with PD-L1 Display in Melanoma: Implications for PD-1 Pathway Blockade.

Taube JM, Young GD, McMiller TL, Chen S, Salas JT, Pritchard TS, Xu H, Meeker AK, Fan J, Cheadle C, Berger AE, Pardoll DM, Topalian SL.

Clin Cancer Res. 2015 Sep 1;21(17):3969-76. doi: 10.1158/1078-0432.CCR-15-0244. Epub 2015 May 5.

11.

Resistin-Like Molecule α in Allergen-Induced Pulmonary Vascular Remodeling.

Fan C, Meuchel LW, Su Q, Angelini DJ, Zhang A, Cheadle C, Kolosova I, Makarevich OD, Yamaji-Kegan K, Rothenberg ME, Johns RA.

Am J Respir Cell Mol Biol. 2015 Sep;53(3):303-13. doi: 10.1165/rcmb.2014-0322OC.

12.

RAP-011, an activin receptor ligand trap, increases hemoglobin concentration in hepcidin transgenic mice.

Langdon JM, Barkataki S, Berger AE, Cheadle C, Xue QL, Sung V, Roy CN.

Am J Hematol. 2015 Jan;90(1):8-14. doi: 10.1002/ajh.23856. Epub 2014 Oct 25.

13.

A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes.

Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF Jr, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF Jr, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celedón JC, Carey VJ, Weiss ST, Raby BA.

J Allergy Clin Immunol. 2014 Nov;134(5):1153-62. doi: 10.1016/j.jaci.2014.04.011. Epub 2014 Jun 13.

14.

Hypoxia-induced mitogenic factor (FIZZ1/RELMα) induces endothelial cell apoptosis and subsequent interleukin-4-dependent pulmonary hypertension.

Yamaji-Kegan K, Takimoto E, Zhang A, Weiner NC, Meuchel LW, Berger AE, Cheadle C, Johns RA.

Am J Physiol Lung Cell Mol Physiol. 2014 Jun 15;306(12):L1090-103. doi: 10.1152/ajplung.00279.2013. Epub 2014 May 2.

15.

Hepcidin-dependent and hepcidin-independent regulation of erythropoiesis in a mouse model of anemia of chronic inflammation.

Langdon JM, Yates SC, Femnou LK, McCranor BJ, Cheadle C, Xue QL, Vaulont S, Civin CI, Walston JD, Roy CN.

Am J Hematol. 2014 May;89(5):470-9. doi: 10.1002/ajh.23670. Epub 2014 Feb 24.

16.

Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age.

McCranor BJ, Langdon JM, Prince OD, Femnou LK, Berger AE, Cheadle C, Civin CI, Kim A, Rivera S, Ganz T, Vaulont S, Xue QL, Walston JD, Roy CN.

Haematologica. 2013 Oct;98(10):1633-40. doi: 10.3324/haematol.2013.087114. Epub 2013 Aug 30.

17.

Stoichiometry of SecYEG in the active translocase of Escherichia coli varies with precursor species.

Mao C, Cheadle CE, Hardy SJ, Lilly AA, Suo Y, Sanganna Gari RR, King GM, Randall LL.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11815-20. doi: 10.1073/pnas.1303289110. Epub 2013 Jul 1.

18.

The first bis-cyanoxime: synthesis and properties of a new versatile and accessible polydentate bifunctional building block for coordination and supramolecular chemistry.

Cheadle C, Gerasimchuk N, Barnes CL, Tyukhtenko SI, Silchenko S.

Dalton Trans. 2013 Apr 14;42(14):4931-46. doi: 10.1039/c2dt31924a.

PMID:
23385567
19.

Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling.

Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Skinner JT, Poloczek A, El-Haddad H, Cheadle C, Johns RA.

Respir Res. 2013 Jan 4;14:1. doi: 10.1186/1465-9921-14-1.

20.

Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases.

Hall JC, Casciola-Rosen L, Berger AE, Kapsogeorgou EK, Cheadle C, Tzioufas AG, Baer AN, Rosen A.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17609-14. doi: 10.1073/pnas.1209724109. Epub 2012 Oct 8.

21.

Effect of luteal-phase support on endometrial microRNA expression following controlled ovarian stimulation.

Zhao Y, Zacur H, Cheadle C, Ning N, Fan J, Vlahos NF.

Reprod Biol Endocrinol. 2012 Sep 6;10:72. doi: 10.1186/1477-7827-10-72.

22.

Resistin-like molecule α stimulates proliferation of mesenchymal stem cells while maintaining their multipotency.

Kolosova IA, Angelini D, Fan C, Skinner J, Cheadle C, Johns RA.

Stem Cells Dev. 2013 Jan 15;22(2):239-47. doi: 10.1089/scd.2012.0192. Epub 2012 Oct 5.

23.

Late stage erythroid precursor production is impaired in mice with chronic inflammation.

Prince OD, Langdon JM, Layman AJ, Prince IC, Sabogal M, Mak HH, Berger AE, Cheadle C, Chrest FJ, Yu Q, Andrews NC, Xue QL, Civin CI, Walston JD, Roy CN.

Haematologica. 2012 Nov;97(11):1648-56. doi: 10.3324/haematol.2011.053397. Epub 2012 May 11.

24.

Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients.

Cheadle C, Berger AE, Mathai SC, Grigoryev DN, Watkins TN, Sugawara Y, Barkataki S, Fan J, Boorgula M, Hummers L, Zaiman AL, Girgis R, McDevitt MA, Johns RA, Wigley F, Barnes KC, Hassoun PM.

PLoS One. 2012;7(4):e34951. doi: 10.1371/journal.pone.0034951. Epub 2012 Apr 24.

25.

Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations.

Almeida MQ, Azevedo MF, Xekouki P, Bimpaki EI, Horvath A, Collins MT, Karaviti LP, Jeha GS, Bhattacharyya N, Cheadle C, Watkins T, Bourdeau I, Nesterova M, Stratakis CA.

J Clin Endocrinol Metab. 2012 Apr;97(4):E687-93. doi: 10.1210/jc.2011-3000. Epub 2012 Jan 18.

26.

Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice.

Podowski M, Calvi C, Metzger S, Misono K, Poonyagariyagorn H, Lopez-Mercado A, Ku T, Lauer T, McGrath-Morrow S, Berger A, Cheadle C, Tuder R, Dietz HC, Mitzner W, Wise R, Neptune E.

J Clin Invest. 2012 Jan;122(1):229-40. doi: 10.1172/JCI46215. Epub 2011 Dec 19.

27.

Transcriptional analysis of infiltrating T cells in kidney ischemia-reperfusion injury reveals a pathophysiological role for CCR5.

Ko GJ, Linfert D, Jang HR, Higbee E, Watkins T, Cheadle C, Liu M, Racusen L, Grigoryev DN, Rabb H.

Am J Physiol Renal Physiol. 2012 Mar 15;302(6):F762-73. doi: 10.1152/ajprenal.00335.2011. Epub 2011 Dec 7.

28.

Array-based nuclear run-on analysis.

Fan J, Chen YC, Watkins T, Dang CV, Gorospe M, Cheadle C.

Methods Mol Biol. 2012;809:505-17. doi: 10.1007/978-1-61779-376-9_33.

29.

Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation.

Ji H, Wu G, Zhan X, Nolan A, Koh C, De Marzo A, Doan HM, Fan J, Cheadle C, Fallahi M, Cleveland JL, Dang CV, Zeller KI.

PLoS One. 2011;6(10):e26057. doi: 10.1371/journal.pone.0026057. Epub 2011 Oct 19.

30.

Critical transition in tissue homeostasis accompanies murine lung senescence.

Calvi CL, Podowski M, D'Alessio FR, Metzger SL, Misono K, Poonyagariyagorn H, Lopez-Mercado A, Ku T, Lauer T, Cheadle C, Talbot CC Jr, Jie C, McGrath-Morrow S, King LS, Walston J, Neptune ER.

PLoS One. 2011;6(6):e20712. doi: 10.1371/journal.pone.0020712. Epub 2011 Jun 21.

31.

rPSGL-Ig for improvement of early liver allograft function: a double-blind, placebo-controlled, single-center phase II study.

Busuttil RW, Lipshutz GS, Kupiec-Weglinski JW, Ponthieux S, Gjertson DW, Cheadle C, Watkins T, Ehrlich E, Katz E, Squiers EC, Rabb H, Hemmerich S.

Am J Transplant. 2011 Apr;11(4):786-97. doi: 10.1111/j.1600-6143.2011.03441.x. Epub 2011 Mar 14.

32.

Pulmonary endothelial cell activation during experimental acute kidney injury.

Feltes CM, Hassoun HT, Lie ML, Cheadle C, Rabb H.

Shock. 2011 Aug;36(2):170-6. doi: 10.1097/SHK.0b013e3182169c76.

33.

Gene expression pathways of high grade localized prostate cancer.

Ross AE, Marchionni L, Vuica-Ross M, Cheadle C, Fan J, Berman DM, Schaeffer EM.

Prostate. 2011 Oct 1;71(14):1568-77. doi: 10.1002/pros.21373. Epub 2011 Feb 25.

PMID:
21360566
34.

Integrated genomic analysis of nodular tissue in macronodular adrenocortical hyperplasia: progression of tumorigenesis in a disorder associated with multiple benign lesions.

Almeida MQ, Harran M, Bimpaki EI, Hsiao HP, Horvath A, Cheadle C, Watkins T, Nesterova M, Stratakis CA.

J Clin Endocrinol Metab. 2011 Apr;96(4):E728-38. doi: 10.1210/jc.2010-2420. Epub 2011 Jan 20.

35.

Chemokine transcripts as targets of the RNA-binding protein HuR in human airway epithelium.

Fan J, Ishmael FT, Fang X, Myers A, Cheadle C, Huang SK, Atasoy U, Gorospe M, Stellato C.

J Immunol. 2011 Feb 15;186(4):2482-94. doi: 10.4049/jimmunol.0903634. Epub 2011 Jan 10.

36.

Tight junction defects in patients with atopic dermatitis.

De Benedetto A, Rafaels NM, McGirt LY, Ivanov AI, Georas SN, Cheadle C, Berger AE, Zhang K, Vidyasagar S, Yoshida T, Boguniewicz M, Hata T, Schneider LC, Hanifin JM, Gallo RL, Novak N, Weidinger S, Beaty TH, Leung DY, Barnes KC, Beck LA.

J Allergy Clin Immunol. 2011 Mar;127(3):773-86.e1-7. doi: 10.1016/j.jaci.2010.10.018. Epub 2010 Dec 15.

37.

Effects of anti-adhesive therapy on kidney biomarkers of ischemia reperfusion injury in human deceased donor kidney allografts.

Cheadle C, Watkins T, Ehrlich E, Barnes K, Gaber AO, Hemmerich S, Rabb H.

Clin Transplant. 2011 Sep-Oct;25(5):766-75. doi: 10.1111/j.1399-0012.2010.01365.x. Epub 2010 Nov 28.

PMID:
21114535
38.

Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors.

Almeida MQ, Tsang KM, Cheadle C, Watkins T, Grivel JC, Nesterova M, Goldbach-Mansky R, Stratakis CA.

Hum Mol Genet. 2011 Jan 1;20(1):165-75. doi: 10.1093/hmg/ddq455. Epub 2010 Oct 11.

39.

Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism.

Yamaji-Kegan K, Su Q, Angelini DJ, Myers AC, Cheadle C, Johns RA.

J Immunol. 2010 Nov 1;185(9):5539-48. doi: 10.4049/jimmunol.0904021. Epub 2010 Oct 1.

40.

CD14, a key candidate gene associated with a specific immune response to cockroach.

Gao P, Grigoryev DN, Rafaels NM, Mu D, Wright JM, Cheadle C, Togias A, Beaty TH, Mathias RA, Schroeder JT, Barnes KC.

Clin Exp Allergy. 2010 Sep;40(9):1353-64. doi: 10.1111/j.1365-2222.2010.03561.x. Epub 2010 Jul 4.

41.

Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone.

Tsang KM, Starost MF, Nesterova M, Boikos SA, Watkins T, Almeida MQ, Harran M, Li A, Collins MT, Cheadle C, Mertz EL, Leikin S, Kirschner LS, Robey P, Stratakis CA.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8683-8. doi: 10.1073/pnas.1003680107. Epub 2010 Apr 26.

42.

Time-dependent c-Myc transactomes mapped by Array-based nuclear run-on reveal transcriptional modules in human B cells.

Fan J, Zeller K, Chen YC, Watkins T, Barnes KC, Becker KG, Dang CV, Cheadle C.

PLoS One. 2010 Mar 15;5(3):e9691. doi: 10.1371/journal.pone.0009691.

43.
44.

Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition.

Ko GJ, Grigoryev DN, Linfert D, Jang HR, Watkins T, Cheadle C, Racusen L, Rabb H.

Am J Physiol Renal Physiol. 2010 Jun;298(6):F1472-83. doi: 10.1152/ajprenal.00619.2009. Epub 2010 Feb 24.

45.

Transcription of proteinase 3 and related myelopoiesis genes in peripheral blood mononuclear cells of patients with active Wegener's granulomatosis.

Cheadle C, Berger AE, Andrade F, James R, Johnson K, Watkins T, Park JK, Chen YC, Ehrlich E, Mullins M, Chrest F, Barnes KC, Levine SM.

Arthritis Rheum. 2010 Jun;62(6):1744-54. doi: 10.1002/art.27398.

46.

Vaccinia virus-specific molecular signature in atopic dermatitis skin.

Grigoryev DN, Howell MD, Watkins TN, Chen YC, Cheadle C, Boguniewicz M, Barnes KC, Leung DY.

J Allergy Clin Immunol. 2010 Jan;125(1):153-159.e28. doi: 10.1016/j.jaci.2009.10.024.

47.

Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling.

Almeida MQ, Muchow M, Boikos S, Bauer AJ, Griffin KJ, Tsang KM, Cheadle C, Watkins T, Wen F, Starost MF, Bossis I, Nesterova M, Stratakis CA.

Hum Mol Genet. 2010 Apr 15;19(8):1387-98. doi: 10.1093/hmg/ddq014. Epub 2010 Jan 15.

48.

GSMA: Gene Set Matrix Analysis, An Automated Method for Rapid Hypothesis Testing of Gene Expression Data.

Cheadle C, Watkins T, Fan J, Williams MA, Georas S, Hall J, Rosen A, Barnes KC.

Bioinform Biol Insights. 2009 Nov 24;1:49-62.

49.

Regulatory T cell-mediated resolution of lung injury: identification of potential target genes via expression profiling.

Aggarwal NR, D'Alessio FR, Tsushima K, Sidhaye VK, Cheadle C, Grigoryev DN, Barnes KC, King LS.

Physiol Genomics. 2010 Apr 1;41(2):109-19. doi: 10.1152/physiolgenomics.00131.2009. Epub 2009 Dec 22. Erratum in: Physiol Genomics. 2016 Dec 1;48(12 ):961.

50.

Complex integration of matrix, oxidative stress, and apoptosis in genetic emphysema.

Podowski M, Calvi CL, Cheadle C, Tuder RM, Biswals S, Neptune ER.

Am J Pathol. 2009 Jul;175(1):84-96. doi: 10.2353/ajpath.2009.080870. Epub 2009 Jun 18.

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