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Items: 1 to 50 of 106

1.

Challenges in the development and exploitation of new therapeutic options targeting the histaminergic system.

Chazot PL, Tiligada E.

Br J Pharmacol. 2020 Feb;177(3):467-468. doi: 10.1111/bph.14947. Epub 2020 Jan 28.

PMID:
31994717
2.

Histamine, histamine receptors, and neuropathic pain relief.

Obara I, Telezhkin V, Alrashdi I, Chazot PL.

Br J Pharmacol. 2020 Feb;177(3):580-599. doi: 10.1111/bph.14696. Epub 2019 Jun 7. Review.

PMID:
31046146
3.

Histamine and Delirium: Current Opinion.

Chazot PL, Johnston L, Mcauley E, Bonner S.

Front Pharmacol. 2019 Apr 9;10:299. doi: 10.3389/fphar.2019.00299. eCollection 2019. Review.

4.

Can H2 -receptor upregulation and raised histamine explain an anaphylactoid reaction on cessation of ranitidine in a 19-year-old female? A case report.

Allen SJ, Chazot PL, Dixon CJ.

Br J Clin Pharmacol. 2018 Jul;84(7):1611-1616. doi: 10.1111/bcp.13578. Epub 2018 Apr 18.

5.

Histamine H4 receptor antagonism prevents the progression of diabetic nephropathy in male DBA2/J mice.

Pini A, Grange C, Veglia E, Argenziano M, Cavalli R, Guasti D, Calosi L, Ghè C, Solarino R, Thurmond RL, Camussi G, Chazot PL, Rosa AC.

Pharmacol Res. 2018 Feb;128:18-28. doi: 10.1016/j.phrs.2018.01.002. Epub 2018 Jan 6.

6.

Medicinal Mascarene Aloes: An audit of their phytotherapeutic potential.

Lobine D, Cummins I, Govinden-Soulange J, Ranghoo-Sanmukhiya M, Lindsey K, Chazot PL, Ambler CA, Grellscheid S, Sharples G, Lall N, Lambrechts IA, Lavergne C, Howes MR.

Fitoterapia. 2018 Jan;124:120-126. doi: 10.1016/j.fitote.2017.10.010. Epub 2017 Oct 21.

PMID:
29066297
7.

Bio-prospecting endemic Mascarene Aloes for potential neuroprotectants.

Lobine D, Howes MR, Cummins I, Govinden-Soulange J, Ranghoo-Sanmukhiya M, Lindsey K, Chazot PL.

Phytother Res. 2017 Dec;31(12):1926-1934. doi: 10.1002/ptr.5941. Epub 2017 Oct 11.

PMID:
29024309
8.

Histamine type 1-receptor activation by low dose of histamine undermines human glomerular slit diaphragm integrity.

Veglia E, Pini A, Moggio A, Grange C, Premoselli F, Miglio G, Tiligada K, Fantozzi R, Chazot PL, Rosa AC.

Pharmacol Res. 2016 Dec;114:27-38. doi: 10.1016/j.phrs.2016.10.011. Epub 2016 Oct 14.

PMID:
27751877
9.

Ligand autoradiographical quantification of histamine H3 receptor in human dementia with Lewy bodies.

Lethbridge NL, Chazot PL.

Pharmacol Res. 2016 Nov;113(Pt A):245-256. doi: 10.1016/j.phrs.2016.08.034. Epub 2016 Aug 31.

10.

Slope climbing challenges, fear of heights, anxiety and time of the day.

Ennaceur A, Hussain MD, Abuhamdah RM, Mostafa RM, Chazot PL.

Behav Brain Res. 2017 Jan 1;316:169-182. doi: 10.1016/j.bbr.2016.09.010. Epub 2016 Sep 5.

PMID:
27609646
11.

Role of histamine H4 receptor ligands in bleomycin-induced pulmonary fibrosis.

Lucarini L, Pini A, Rosa AC, Lanzi C, Durante M, Chazot PL, Krief S, Schreeb A, Stark H, Masini E.

Pharmacol Res. 2016 Sep;111:740-748. doi: 10.1016/j.phrs.2016.07.037. Epub 2016 Jul 27.

PMID:
27475884
12.

Histamine in diabetes: Is it time to reconsider?

Pini A, Obara I, Battell E, Chazot PL, Rosa AC.

Pharmacol Res. 2016 Sep;111:316-324. doi: 10.1016/j.phrs.2016.06.021. Epub 2016 Jun 22. Review.

PMID:
27343700
13.

Pre-training in a radial arm maze abolished anxiety and impaired habituation in C57BL6/J mice treated with dizocilpine.

Abuhamdah RM, Hussain MD, Chazot PL, Ennaceur A.

Physiol Behav. 2016 Oct 1;164(Pt A):353-60. doi: 10.1016/j.physbeh.2016.06.017. Epub 2016 Jun 16.

PMID:
27317838
14.

Preclinical animal anxiety research - flaws and prejudices.

Ennaceur A, Chazot PL.

Pharmacol Res Perspect. 2016 Mar 8;4(2):e00223. doi: 10.1002/prp2.223. eCollection 2016 Apr. Review.

15.

Altered GABAA α5 subunit expression in the hypothalamic paraventricular nucleus of hypertensive and pregnant rats.

Cork SC, Chazot PL, Pyner S.

Neurosci Lett. 2016 May 4;620:148-53. doi: 10.1016/j.neulet.2016.03.031. Epub 2016 Mar 30.

16.

Activity- and development-dependent down-regulation of TARPγ8 and GluA1 in cultured rat hippocampal neurons.

Wang JG, Wang YL, Xu F, Zhao JX, Zhou SY, Yu Y, Chazot PL, Wang XF, Lu CB.

Acta Pharmacol Sin. 2016 Mar;37(3):303-11. doi: 10.1038/aps.2015.112. Epub 2016 Jan 4.

17.

Effects of chronic fluoxetine treatment on anxious behaviour of BALB/c mice in a 3-dimensional maze.

Abuhamdah RM, Hussain MD, Chazot PL, Ennaceur A.

Stress. 2015;18(6):677-85. doi: 10.3109/10253890.2015.1083550. Epub 2015 Sep 12.

PMID:
26365460
18.

The European Histamine Research Society 44th Annual Meeting, May 6-9, 2015 Malaga, Spain.

Sturman G, Barrett K, Carruthers N, Ennis M, Pearce FL, Bell D, Chazot PL, Gibbs B.

Inflamm Res. 2015 Jul;64 Suppl 1:S1-50. doi: 10.1007/s00011-015-0842-9. No abstract available.

PMID:
26160655
19.

International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors.

Panula P, Chazot PL, Cowart M, Gutzmer R, Leurs R, Liu WL, Stark H, Thurmond RL, Haas HL.

Pharmacol Rev. 2015 Jul;67(3):601-55. doi: 10.1124/pr.114.010249. Review.

20.

Pharmacological and neuroprotective profile of an essential oil derived from leaves of Aloysia citrodora Palau.

Abuhamdah S, Abuhamdah R, Howes MJ, Al-Olimat S, Ennaceur A, Chazot PL.

J Pharm Pharmacol. 2015 Sep;67(9):1306-15. doi: 10.1111/jphp.12424. Epub 2015 Apr 16.

PMID:
25877296
21.

Activation of histamine H3 receptor decreased cytoplasmic Ca(2+) imaging during electrical stimulation in the skeletal myotubes.

Chen Y, Paavola J, Stegajev V, Stark H, Chazot PL, Wen JG, Konttinen YT.

Eur J Pharmacol. 2015 May 5;754:173-8. doi: 10.1016/j.ejphar.2015.02.035. Epub 2015 Mar 3.

PMID:
25746421
22.

H3 receptor renal expression in normal and diabetic rats.

Pini A, Chazot PL, Veglia E, Moggio A, Rosa AC.

Inflamm Res. 2015 May;64(5):271-3. doi: 10.1007/s00011-015-0808-y. Epub 2015 Mar 7.

23.

Histamine receptor expression in human renal tubules: a comparative pharmacological evaluation.

Veglia E, Grange C, Pini A, Moggio A, Lanzi C, Camussi G, Chazot PL, Rosa AC.

Inflamm Res. 2015 Apr;64(3-4):261-70. doi: 10.1007/s00011-015-0807-z. Epub 2015 Mar 1.

24.

Identification of histamine receptor subtypes in skeletal myogenesis.

Chen Y, Stegaev V, Kouri VP, Sillat T, Chazot PL, Stark H, Wen JG, Konttinen YT.

Mol Med Rep. 2015 Apr;11(4):2624-30. doi: 10.3892/mmr.2014.3073. Epub 2014 Dec 10.

25.

The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils.

Dib K, Perecko T, Jenei V, McFarlane C, Comer D, Brown V, Katebe M, Scheithauer T, Thurmond RL, Chazot PL, Ennis M.

J Leukoc Biol. 2014 Sep;96(3):411-8. doi: 10.1189/jlb.2AB0813-432RR. Epub 2014 May 5.

26.

Histamine pharmacology: four years on.

Chazot PL.

Br J Pharmacol. 2013 Sep;170(1):1-3. doi: 10.1111/bph.12319.

27.

Antagonism of histamine H4 receptors exacerbates clinical and pathological signs of experimental autoimmune encephalomyelitis.

Ballerini C, Aldinucci A, Luccarini I, Galante A, Manuelli C, Blandina P, Katebe M, Chazot PL, Masini E, Passani MB.

Br J Pharmacol. 2013 Sep;170(1):67-77. doi: 10.1111/bph.12263.

28.

Histamine transport and metabolism are deranged in salivary glands in Sjogren's syndrome.

Stegaev V, Nies AT, Porola P, Mieliauskaite D, Sánchez-Jiménez F, Urdiales JL, Sillat T, Schwelberger HG, Chazot PL, Katebe M, Mackiewicz Z, Konttinen YT, Nordström DC.

Rheumatology (Oxford). 2013 Sep;52(9):1599-608. doi: 10.1093/rheumatology/ket188. Epub 2013 May 24.

PMID:
23709238
29.

Non-invasive infra-red therapy (1072 nm) reduces β-amyloid protein levels in the brain of an Alzheimer's disease mouse model, TASTPM.

Grillo SL, Duggett NA, Ennaceur A, Chazot PL.

J Photochem Photobiol B. 2013 Jun 5;123:13-22. doi: 10.1016/j.jphotobiol.2013.02.015. Epub 2013 Mar 22.

PMID:
23603448
30.

Overexpression of histamine H₄ receptors in the kidney of diabetic rat.

Rosa AC, Grange C, Pini A, Katebe MA, Benetti E, Collino M, Miglio G, Bani D, Camussi G, Chazot PL, Fantozzi R.

Inflamm Res. 2013 Apr;62(4):357-65. doi: 10.1007/s00011-012-0587-7. Epub 2012 Dec 22.

31.

Effects of methimepip and JNJ-5207852 in Wistar rats exposed to an open-field with and without object and in Balb/c mice exposed to a radial-arm maze.

Abuhamdah RM, van Rensburg R, Lethbridge NL, Ennaceur A, Chazot PL.

Front Syst Neurosci. 2012 Jul 16;6:54. doi: 10.3389/fnsys.2012.00054. eCollection 2012.

32.

Brief report: first identification of H₄ histamine receptor in healthy salivary glands and in focal sialadenitis in Sjögren's syndrome.

Stegaev V, Sillat T, Porola P, Hänninen A, Falus A, Mieliauskaite D, Buzás E, Rotar Z, Mackiewicz Z, Stark H, Chazot PL, Konttinen YT.

Arthritis Rheum. 2012 Aug;64(8):2663-8. doi: 10.1002/art.34484.

33.

Well characterized antihistamine 4 receptor antibodies contribute to current knowledge of the expression and biology of the human and murine histamine 4 receptor.

Gutzmer R, Werfel T, Bäumer W, Kietzmann M, Chazot PL, Leurs R.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Sep;385(9):853-4; author reply 855-60. doi: 10.1007/s00210-012-0744-0. Epub 2012 Mar 14. No abstract available.

PMID:
22411357
34.

Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study.

Shan L, Bossers K, Luchetti S, Balesar R, Lethbridge N, Chazot PL, Bao AM, Swaab DF.

Neurobiol Aging. 2012 Jul;33(7):1488.e1-13. doi: 10.1016/j.neurobiolaging.2011.10.016. Epub 2011 Nov 26.

PMID:
22118942
35.

Histamine pharmacology and new CNS drug targets.

Tiligada E, Kyriakidis K, Chazot PL, Passani MB.

CNS Neurosci Ther. 2011 Dec;17(6):620-8. doi: 10.1111/j.1755-5949.2010.00212.x. Epub 2010 Nov 22. Review.

36.

MK-801 increases the baseline level of anxiety in mice introduced to a spatial memory task without prior habituation.

Ennaceur A, Michalikova S, van Rensburg R, Chazot PL.

Neuropharmacology. 2011 Oct-Nov;61(5-6):981-91. doi: 10.1016/j.neuropharm.2011.06.027. Epub 2011 Jul 6.

PMID:
21762710
37.

Effects of NMDA receptor antagonists with different subtype selectivities on retinal spreading depression.

Wang M, Chazot PL, Ali S, Duckett SF, Obrenovitch TP.

Br J Pharmacol. 2012 Jan;165(1):235-44. doi: 10.1111/j.1476-5381.2011.01553.x.

38.

Therapeutic potential of histamine H3 receptor antagonists in dementias.

Chazot PL.

Drug News Perspect. 2010 Mar;23(2):99-103. doi: 10.1358/dnp.2010.23.2.1475899.

PMID:
20369074
39.

Tolerance, sensitization and dependence to diazepam in Balb/c mice exposed to a novel open space anxiety test.

Ennaceur A, Michalikova S, van Rensburg R, Chazot PL.

Behav Brain Res. 2010 May 1;209(1):154-64. doi: 10.1016/j.bbr.2010.01.039. Epub 2010 Feb 1.

PMID:
20117142
40.

Immunological identification of the mouse H4 histamine receptor on spinal cord motor neurons using a novel anti-mouse H4R antibody.

Lethbridge NL, Chazot PL.

Inflamm Res. 2010 Mar;59 Suppl 2:S197-8. doi: 10.1007/s00011-009-0127-2.

PMID:
20020316
41.

Anxiety responses in Balb/c, c57 and CD-1 mice exposed to a novel open space test.

Michalikova S, van Rensburg R, Chazot PL, Ennaceur A.

Behav Brain Res. 2010 Mar 5;207(2):402-17. doi: 10.1016/j.bbr.2009.10.028. Epub 2009 Nov 10.

PMID:
19900487
42.

Distinguishing anxiolysis and hyperactivity in an open space behavioral test.

Ennaceur A, Michalikova S, van Rensburg R, Chazot PL.

Behav Brain Res. 2010 Feb 11;207(1):84-98. doi: 10.1016/j.bbr.2009.09.042. Epub 2009 Oct 2.

PMID:
19800918
43.

Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat.

Giannoni P, Passani MB, Nosi D, Chazot PL, Shenton FC, Medhurst AD, Munari L, Blandina P.

Eur J Neurosci. 2009 Jun;29(12):2363-74. doi: 10.1111/j.1460-9568.2009.06765.x. Epub 2009 May 22.

PMID:
19490084
44.

The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS.

Connelly WM, Shenton FC, Lethbridge N, Leurs R, Waldvogel HJ, Faull RL, Lees G, Chazot PL.

Br J Pharmacol. 2009 May;157(1):55-63. doi: 10.1111/j.1476-5381.2009.00227.x.

45.

Molecular and biochemical pharmacology of the histamine H4 receptor.

Leurs R, Chazot PL, Shenton FC, Lim HD, de Esch IJ.

Br J Pharmacol. 2009 May;157(1):14-23. doi: 10.1111/j.1476-5381.2009.00250.x. Review.

46.

Advances in histamine pharmacology reveal new drug targets.

Chazot PL.

Br J Pharmacol. 2009 May;157(1):1-3. doi: 10.1111/j.1476-5381.2009.00228.x.

47.

Generation and characterisation of the first anti-human H3R445/453 isoform specific antibody probe.

Lethbridge NL, Shenton FC, Chazot PL.

Inflamm Res. 2009 Apr;58 Suppl 1:43-4. doi: 10.1007/s00011-009-2000-8. No abstract available.

PMID:
19271149
48.

British Pharmacology Society Winter Meeting: focus on neuropharmacology.

Burroughs S, Lethbridge N, Chazot PL.

Expert Rev Clin Pharmacol. 2009 Mar;2(2):163-7. doi: 10.1586/17512433.2.2.163.

PMID:
24410647
49.

A new model for the study of high-K(+)-induced preconditioning in cultured neurones: role of N-methyl-d-aspartate and alpha7-nicotinic acetylcholine receptors.

van Rensburg R, Errington DR, Ennaceur A, Lees G, Obrenovitch TP, Chazot PL.

J Neurosci Methods. 2009 Mar 15;177(2):311-6. doi: 10.1016/j.jneumeth.2008.10.012. Epub 2008 Oct 21.

PMID:
19007816
50.

Do rats really express neophobia towards novel objects? Experimental evidence from exposure to novelty and to an object recognition task in an open space and an enclosed space.

Ennaceur A, Michalikova S, Chazot PL.

Behav Brain Res. 2009 Feb 11;197(2):417-34. doi: 10.1016/j.bbr.2008.10.007. Epub 2008 Oct 15.

PMID:
18992282

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