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Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model.

Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Kline Z, Belt P, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.

Anticancer Res. 2019 Sep;39(9):4781-4786. doi: 10.21873/anticanres.13662.


Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma.

Higuchi T, Oshiro H, Miyake K, Sugisawa N, Han Q, Tan Y, Park J, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Chawla SP, Singh SR, Tsuchiya H, Hoffman RM.

Anticancer Res. 2019 Sep;39(9):4653-4657. doi: 10.21873/anticanres.13646.


Altered Levels of Toll-Like Receptors in Circulating Extracellular Vesicles in Multiple Sclerosis.

Bhargava P, Nogueras-Ortiz C, Chawla S, Bæk R, Jørgensen MM, Kapogiannis D.

Cells. 2019 Sep 10;8(9). pii: E1058. doi: 10.3390/cells8091058.


Validation of a QuEChERS-Based Method for the Estimation of Afidopyropen in Brinjal (Solanum Melongena L.) and Soil.

Chawla S, Gor HN, Patel HK, Upadhyay PP, Shah PG.

J AOAC Int. 2019 Sep 9. doi: 10.5740/jaoacint.19-0206. [Epub ahead of print]


Examining the Evidence for an Adult Healthy Middle Ear Microbiome.

Jervis-Bardy J, Leong LEX, Papanicolas LE, Ivey KL, Chawla S, Woods CM, Frauenfelder C, Ooi EH, Rogers GB.

mSphere. 2019 Sep 4;4(5). pii: e00456-19. doi: 10.1128/mSphere.00456-19.


A predictive model for extubation readiness in extremely preterm infants.

Gupta D, Greenberg RG, Sharma A, Natarajan G, Cotten M, Thomas R, Chawla S.

J Perinatol. 2019 Aug 27. doi: 10.1038/s41372-019-0475-x. [Epub ahead of print]


Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model.

Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.

Anticancer Res. 2019 Aug;39(8):4079-4084. doi: 10.21873/anticanres.13565.


Phase 1 study of the MDM2 inhibitor AMG 232 in patients with advanced P53 wild-type solid tumors or multiple myeloma.

Gluck WL, Gounder MM, Frank R, Eskens F, Blay JY, Cassier PA, Soria JC, Chawla S, de Weger V, Wagner AJ, Siegel D, De Vos F, Rasmussen E, Henary HA.

Invest New Drugs. 2019 Jul 29. doi: 10.1007/s10637-019-00840-1. [Epub ahead of print]


Association of Extracellular Vesicle Biomarkers With Alzheimer Disease in the Baltimore Longitudinal Study of Aging.

Kapogiannis D, Mustapic M, Shardell MD, Berkowitz ST, Diehl TC, Spangler RD, Tran J, Lazaropoulos MP, Chawla S, Gulyani S, Eitan E, An Y, Huang CW, Oh ES, Lyketsos CG, Resnick SM, Goetzl EJ, Ferrucci L.

JAMA Neurol. 2019 Jul 15. doi: 10.1001/jamaneurol.2019.2462. [Epub ahead of print]


Levofloxacin induced Desquamation: A Rare Case Report.

Gill GK, Chhabra M, Chawla SPS.

Curr Drug Saf. 2019 Jul 8. doi: 10.2174/1574886314666190708152223. [Epub ahead of print]


A neurotoxin that specifically targets Anopheles mosquitoes.

Contreras E, Masuyer G, Qureshi N, Chawla S, Dhillon HS, Lee HL, Chen J, Stenmark P, Gill SS.

Nat Commun. 2019 Jun 28;10(1):2869. doi: 10.1038/s41467-019-10732-w.


The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model.

Miyake K, Higuchi T, Oshiro H, Zhang Z, Sugisawa N, Park JH, Razmjooei S, Katsuya Y, Barangi M, Li Y, Nelson SD, Murakami T, Homma Y, Hiroshima Y, Matsuyama R, Bouvet M, Chawla SP, Singh SR, Endo I, Hoffman RM.

Biomed Pharmacother. 2019 Sep;117:109093. doi: 10.1016/j.biopha.2019.109093. Epub 2019 Jun 11.


Evaluation of obstructive sleep apnea in metabolic syndrome.

Soin D, Kumar PA, Chahal J, Chawla SPS, Kaur S, Garg R, Kaur R.

J Family Med Prim Care. 2019 May;8(5):1580-1586. doi: 10.4103/jfmpc.jfmpc_175_19.


Overall survival and histology-specific subgroup analyses from a phase 3, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma.

Patel S, von Mehren M, Reed DR, Kaiser P, Charlson J, Ryan CW, Rushing D, Livingston M, Singh A, Seth R, Forscher C, D'Amato G, Chawla SP, McCarthy S, Wang G, Parekh T, Knoblauch R, Hensley ML, Maki RG, Demetri GD.

Cancer. 2019 Aug 1;125(15):2610-2620. doi: 10.1002/cncr.32117. Epub 2019 Jun 7.


Safe, Effective Chin and Jaw Restoration With VYC-25L Hyaluronic Acid Injectable Gel.

Ogilvie P, Sattler G, Gaymans F, Belhaouari L, Weichman BM, Snow S, Chawla S, Abrams S, Schumacher A.

Dermatol Surg. 2019 May 22. doi: 10.1097/DSS.0000000000001960. [Epub ahead of print]


Lack of choline elevation on proton magnetic resonance spectroscopy in grade I-III gliomas.

Chawla S, Lee SC, Mohan S, Wang S, Nasrallah M, Vossough A, Krejza J, Melhem ER, Nabavizadeh SA.

Neuroradiol J. 2019 Aug;32(4):250-258. doi: 10.1177/1971400919846509. Epub 2019 May 3.


Towards Deep-Learning-Driven Intrusion Detection for the Internet of Things.

Thamilarasu G, Chawla S.

Sensors (Basel). 2019 Apr 27;19(9). pii: E1977. doi: 10.3390/s19091977.


A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb-004) in metastatic soft-tissue sarcomas.

Jones RL, Chawla SP, Attia S, Schöffski P, Gelderblom H, Chmielowski B, Le Cesne A, Van Tine BA, Trent JC, Patel S, Wagner AJ, Chugh R, Heyburn JW, Weil SC, Wang W, Viele K, Maki RG.

Cancer. 2019 Jul 15;125(14):2445-2454. doi: 10.1002/cncr.32084. Epub 2019 Apr 29.


Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma.

Davis LE, Bolejack V, Ryan CW, Ganjoo KN, Loggers ET, Chawla S, Agulnik M, Livingston MB, Reed D, Keedy V, Rushing D, Okuno S, Reinke DK, Riedel RF, Attia S, Mascarenhas L, Maki RG.

J Clin Oncol. 2019 Jun 1;37(16):1424-1431. doi: 10.1200/JCO.18.02374. Epub 2019 Apr 23.


Disseminated Trichosporon asahii infection in a combined liver-kidney transplant recipient successfully treated with voriconazole.

Sah R, Soin AS, Chawla S, Wadhwa T, Gupta N.

Immun Inflamm Dis. 2019 Sep;7(3):125-129. doi: 10.1002/iid3.250. Epub 2019 Apr 20.


Asymptomatic bacteriuria among the patients of type 2 diabetes mellitus.

Bharti A, Chawla SPS, Kumar S, Kaur S, Soin D, Jindal N, Garg R.

J Family Med Prim Care. 2019 Feb;8(2):539-543. doi: 10.4103/jfmpc.jfmpc_403_18.


Extreme hyperbilirubinemia: An indicator of morbidity and mortality in sickle cell disease.

Haydek JP, Taborda C, Shah R, Reshamwala PA, McLemore ML, Rassi FE, Chawla S.

World J Hepatol. 2019 Mar 27;11(3):287-293. doi: 10.4254/wjh.v11.i3.287.


Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model.

Higuchi T, Miyake K, Oshiro H, Sugisawa N, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.

Biochem Biophys Res Commun. 2019 May 28;513(2):326-331. doi: 10.1016/j.bbrc.2019.03.191. Epub 2019 Apr 5.


Concomitant medication use and clinical outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment of Major Depressive Disorder.

Hunter AM, Minzenberg MJ, Cook IA, Krantz DE, Levitt JG, Rotstein NM, Chawla SA, Leuchter AF.

Brain Behav. 2019 May;9(5):e01275. doi: 10.1002/brb3.1275. Epub 2019 Apr 2.


Impact of health education on knowledge, attitude, practices and glycemic control in type 2 diabetes mellitus.

Chawla SPS, Kaur S, Bharti A, Garg R, Kaur M, Soin D, Ghosh A, Pal R.

J Family Med Prim Care. 2019 Jan;8(1):261-268. doi: 10.4103/jfmpc.jfmpc_228_18.


Extracellular vesicles reveal abnormalities in neuronal iron metabolism in restless legs syndrome.

Chawla S, Gulyani S, Allen RP, Earley CJ, Li X, Van Zijl P, Kapogiannis D.

Sleep. 2019 Jul 8;42(7). pii: zsz079. doi: 10.1093/sleep/zsz079.


Acute Hypobaric Hypoxia-Mediated Biochemical/Metabolic Shuffling and Differential Modulation of S1PR-SphK in Cardiac and Skeletal Muscles.

Rahar B, Chawla S, Tulswani R, Saxena S.

High Alt Med Biol. 2019 Mar;20(1):78-88. doi: 10.1089/ham.2018.0046.


Aldoxorubicin in soft tissue sarcomas.

Chamberlain FE, Jones RL, Chawla SP.

Future Oncol. 2019 May;15(13):1429-1435. doi: 10.2217/fon-2018-0922. Epub 2019 Mar 15. Review.


Tumor thrombus in the venous drainage pathways of primary, recurrent and metastatic disease on routine oncologic imaging studies: beyond hepatocellular and renal cell carcinomas.

Yedururi S, Kang H, Cox VL, Chawla S, Le O, Loyer EM, Marcal L.

Br J Radiol. 2019 Jun;92(1098):20180478. doi: 10.1259/bjr.20180478. Epub 2019 Apr 24.


Diagnostic and therapeutic considerations for obscure gastrointestinal bleeding in patients with chronic kidney disease.

Muftah M, Mulki R, Dhere T, Keilin S, Chawla S.

Ann Gastroenterol. 2019 Mar-Apr;32(2):113-123. doi: 10.20524/aog.2018.0341. Epub 2018 Dec 20. Review.


Role of pancreatoscopy in management of pancreatic disease: A systematic review.

Kaura T, Willingham FF, Chawla S.

World J Gastrointest Endosc. 2019 Feb 16;11(2):155-167. doi: 10.4253/wjge.v11.i2.155.


Detection of occult neoplastic infiltration in the corpus callosum and prediction of overall survival in patients with glioblastoma using diffusion tensor imaging.

Mohan S, Wang S, Coban G, Kural F, Chawla S, O'Rourke DM, Poptani H.

Eur J Radiol. 2019 Mar;112:106-111. doi: 10.1016/j.ejrad.2019.01.015. Epub 2019 Jan 15.


Regorafenib regressed a doxorubicin-resistant Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model.

Miyake K, Kiyuna T, Kawaguchi K, Higuchi T, Oshiro H, Zhang Z, Wangsiricharoen S, Razmjooei S, Li Y, Nelson SD, Murakami T, Hiroshima Y, Matsuyama R, Bouvet M, Chawla SP, Singh SR, Endo I, Hoffman RM.

Cancer Chemother Pharmacol. 2019 May;83(5):809-815. doi: 10.1007/s00280-019-03782-w. Epub 2019 Feb 13.


Alpha Particle Radium 223 Dichloride in High-risk Osteosarcoma: A Phase I Dose Escalation Trial.

Subbiah V, Anderson PM, Kairemo K, Hess K, Huh WW, Ravi V, Daw NC, Somaiah N, Ludwig JA, Benjamin RS, Chawla S, Hong DS, Meric-Bernstam F, Ravizzini G, Kleinerman E, Macapinlac H, Rohren E.

Clin Cancer Res. 2019 Jul 1;25(13):3802-3810. doi: 10.1158/1078-0432.CCR-18-3964. Epub 2019 Feb 7.


Effect of sofosbuvir and daclatasvir on lipid profile, glycemic control and quality of life index in chronic hepatitis C, genotype 3 patients.

Jain A, Kalra BS, Srivastava S, Chawla S.

Indian J Gastroenterol. 2019 Feb;38(1):39-43. doi: 10.1007/s12664-019-00935-w. Epub 2019 Feb 2.


A Phase I-II Study Using Rexin-G Tumor-Targeted Retrovector Encoding a Dominant-Negative Cyclin G1 Inhibitor for Advanced Pancreatic Cancer.

Chawla SP, Bruckner H, Morse MA, Assudani N, Hall FL, Gordon EM.

Mol Ther Oncolytics. 2018 Dec 14;12:56-67. doi: 10.1016/j.omto.2018.12.005. eCollection 2019 Mar 29.


Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model.

Miyake K, Kiyuna T, Miyake M, Kawaguchi K, Zhang Z, Wangsiricharoen S, Razmjooei S, Oshiro H, Higuchi T, Li Y, Nelson SD, Murakami T, Hiroshima Y, Kumamoto T, Matsuyama R, Bouvet M, Singh SR, Chawla SP, Endo I, Hoffman RM.

Biochem Biophys Res Commun. 2019 Feb 19;509(4):1041-1046. doi: 10.1016/j.bbrc.2019.01.046. Epub 2019 Jan 16.


A novel approach to outpatient clinic management.

Chawla S.

Br J Dermatol. 2019 Jun;180(6):1560-1561. doi: 10.1111/bjd.17643. Epub 2019 Mar 20. No abstract available.


Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease: A Secondary Analysis of the Exenatide-PD Trial.

Athauda D, Gulyani S, Karnati HK, Li Y, Tweedie D, Mustapic M, Chawla S, Chowdhury K, Skene SS, Greig NH, Kapogiannis D, Foltynie T.

JAMA Neurol. 2019 Apr 1;76(4):420-429. doi: 10.1001/jamaneurol.2018.4304. Erratum in: JAMA Neurol. 2019 Apr 1;76(4):509.


Endoscopic removal of a silastic gastric band.

Mulki R, Lin E, Chawla S.

VideoGIE. 2018 Oct 31;4(1):20-21. doi: 10.1016/j.vgie.2018.09.004. eCollection 2019 Jan. No abstract available.


The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.

Higuchi T, Kawaguchi K, Miyake K, Oshiro H, Zhang Z, Razmjooei S, Wangsiricharoen S, Igarashi K, Yamamoto N, Hayashi K, Kimura H, Miwa S, Nelson SD, Dry SM, Li Y, Chawla SP, Eilber FC, Singh SR, Tsuchiya H, Hoffman RM.

Biomed Pharmacother. 2019 Mar;111:835-840. doi: 10.1016/j.biopha.2018.12.110. Epub 2019 Jan 4.


Plasma neuronal exosomes serve as biomarkers of cognitive impairment in HIV infection and Alzheimer's disease.

Pulliam L, Sun B, Mustapic M, Chawla S, Kapogiannis D.

J Neurovirol. 2019 Jan 4. doi: 10.1007/s13365-018-0695-4. [Epub ahead of print]


Exploiting Oncogenic Drivers along the CCNG1 Pathway for Cancer Therapy and Gene Therapy.

Al-Shihabi A, Chawla SP, Hall FL, Gordon EM.

Mol Ther Oncolytics. 2018 Dec 12;11:122-126. doi: 10.1016/j.omto.2018.11.002. eCollection 2018 Dec 21. Review. No abstract available.


Three-dimensional echo planar spectroscopic imaging for differentiation of true progression from pseudoprogression in patients with glioblastoma.

Verma G, Chawla S, Mohan S, Wang S, Nasrallah M, Sheriff S, Desai A, Brem S, O'Rourke DM, Wolf RL, Maudsley AA, Poptani H.

NMR Biomed. 2019 Feb;32(2):e4042. doi: 10.1002/nbm.4042. Epub 2018 Dec 17.


Identifying the barriers to gastric cancer care at safety-net hospitals: A novel comparison of a safety-net hospital to a neighboring quaternary referral academic center in the same healthcare system.

Zaidi MY, Rappaport JM, Ethun CG, Gillespie T, Hawk N, Chawla S, Cardona K, Maithel SK, Russell MC.

J Surg Oncol. 2019 Jan;119(1):64-70. doi: 10.1002/jso.25299. Epub 2018 Nov 27.


Multiparametric magnetic resonance imaging in the assessment of anti-EGFRvIII chimeric antigen receptor T cell therapy in patients with recurrent glioblastoma.

Wang S, O'Rourke DM, Chawla S, Verma G, Nasrallah MP, Morrissette JJD, Plesa G, June CH, Brem S, Maloney E, Desai A, Wolf RL, Poptani H, Mohan S.

Br J Cancer. 2019 Jan;120(1):54-56. doi: 10.1038/s41416-018-0342-0. Epub 2018 Nov 27.


Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study.

Lally PJ, Montaldo P, Oliveira V, Soe A, Swamy R, Bassett P, Mendoza J, Atreja G, Kariholu U, Pattnayak S, Sashikumar P, Harizaj H, Mitchell M, Ganesh V, Harigopal S, Dixon J, English P, Clarke P, Muthukumar P, Satodia P, Wayte S, Abernethy LJ, Yajamanyam K, Bainbridge A, Price D, Huertas A, Sharp DJ, Kalra V, Chawla S, Shankaran S, Thayyil S; MARBLE consortium.

Lancet Neurol. 2019 Jan;18(1):35-45. doi: 10.1016/S1474-4422(18)30325-9. Epub 2018 Nov 15.


Oncologic Emergencies-The Old, the New, and the Deadly.

Thandra K, Salah Z, Chawla S.

J Intensive Care Med. 2018 Nov 9:885066618803863. doi: 10.1177/0885066618803863. [Epub ahead of print]


Interplay between hereditary and environmental factors to establish an in vitro disease model of keratoconus.

Roy S, Yadav S, Dasgupta T, Chawla S, Tandon R, Ghosh S.

Drug Discov Today. 2019 Feb;24(2):403-416. doi: 10.1016/j.drudis.2018.10.017. Epub 2018 Nov 5. Review.


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