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Items: 24


Cdx2 Animal Models Reveal Developmental Origins of Cancers.

Chawengsaksophak K.

Genes (Basel). 2019 Nov 14;10(11). pii: E928. doi: 10.3390/genes10110928. Review.


Author Correction: The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.

Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K.

Sci Rep. 2018 Apr 5;8(1):5762. doi: 10.1038/s41598-018-22650-w.


The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.

Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K.

Sci Rep. 2017 Aug 24;7(1):9322. doi: 10.1038/s41598-017-09490-w. Erratum in: Sci Rep. 2018 Apr 5;8(1):5762.


Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice.

Vrbacký M, Kovalčíková J, Chawengsaksophak K, Beck IM, Mráček T, Nůsková H, Sedmera D, Papoušek F, Kolář F, Sobol M, Hozák P, Sedlacek R, Houštěk J.

Hum Mol Genet. 2016 Nov 1;25(21):4674-4685. doi: 10.1093/hmg/ddw295.


A site-specific, single-copy transgenesis strategy to identify 5' regulatory sequences of the mouse testis-determining gene Sry.

Quinn A, Kashimada K, Davidson TL, Ng ET, Chawengsaksophak K, Bowles J, Koopman P.

PLoS One. 2014 Apr 17;9(4):e94813. doi: 10.1371/journal.pone.0094813. eCollection 2014.


Tmem26 is dynamically expressed during palate and limb development but is not required for embryonic survival.

Town L, McGlinn E, Davidson TL, Browne CM, Chawengsaksophak K, Koopman P, Richman JM, Wicking C.

PLoS One. 2011;6(9):e25228. doi: 10.1371/journal.pone.0025228. Epub 2011 Sep 29.


Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice.

Chawengsaksophak K, Svingen T, Ng ET, Epp T, Spiller CM, Clark C, Cooper H, Koopman P.

Biol Reprod. 2012 Jan 10;86(1):1-12. doi: 10.1095/biolreprod.111.095232. Print 2012 Jan.


Cdx1 refines positional identity of the vertebrate hindbrain by directly repressing Mafb expression.

Sturgeon K, Kaneko T, Biemann M, Gauthier A, Chawengsaksophak K, Cordes SP.

Development. 2011 Jan;138(1):65-74. doi: 10.1242/dev.058727. Epub 2010 Nov 23.


Cdx gene deficiency compromises embryonic hematopoiesis in the mouse.

Wang Y, Yabuuchi A, McKinney-Freeman S, Ducharme DM, Ray MK, Chawengsaksophak K, Archer TK, Daley GQ.

Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7756-61. doi: 10.1073/pnas.0708951105. Epub 2008 May 29.


Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.

Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J.

J Clin Invest. 2007 Nov;117(11):3369-82.


Trophoblast-specific gene manipulation using lentivirus-based vectors.

Georgiades P, Cox B, Gertsenstein M, Chawengsaksophak K, Rossant J.

Biotechniques. 2007 Mar;42(3):317-8, 320, 322-5.


Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry.

Takeuchi JK, Lickert H, Bisgrove BW, Sun X, Yamamoto M, Chawengsaksophak K, Hamada H, Yost HJ, Rossant J, Bruneau BG.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):846-51. Epub 2007 Jan 8.


Retinoid signaling determines germ cell fate in mice.

Bowles J, Knight D, Smith C, Wilhelm D, Richman J, Mamiya S, Yashiro K, Chawengsaksophak K, Wilson MJ, Rossant J, Hamada H, Koopman P.

Science. 2006 Apr 28;312(5773):596-600. Epub 2006 Mar 30.


Endothelial cells and VEGF in vascular development.

Coultas L, Chawengsaksophak K, Rossant J.

Nature. 2005 Dec 15;438(7070):937-45. Review.


Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst.

Strumpf D, Mao CA, Yamanaka Y, Ralston A, Chawengsaksophak K, Beck F, Rossant J.

Development. 2005 May;132(9):2093-102. Epub 2005 Mar 23.


Cdx2 is essential for axial elongation in mouse development.

Chawengsaksophak K, de Graaff W, Rossant J, Deschamps J, Beck F.

Proc Natl Acad Sci U S A. 2004 May 18;101(20):7641-5. Epub 2004 May 10.


The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.

Bonhomme C, Duluc I, Martin E, Chawengsaksophak K, Chenard MP, Kedinger M, Beck F, Freund JN, Domon-Dell C.

Gut. 2003 Oct;52(10):1465-71.


A study of regional gut endoderm potency by analysis of Cdx2 null mutant chimaeric mice.

Beck F, Chawengsaksophak K, Luckett J, Giblett S, Tucci J, Brown J, Poulsom R, Jeffery R, Wright NA.

Dev Biol. 2003 Mar 15;255(2):399-406.


Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation.

van den Akker E, Forlani S, Chawengsaksophak K, de Graaff W, Beck F, Meyer BI, Deschamps J.

Development. 2002 May;129(9):2181-93.


Homeobox genes and gut development.

Beck F, Tata F, Chawengsaksophak K.

Bioessays. 2000 May;22(5):431-41. Review.


Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice.

Beck F, Chawengsaksophak K, Waring P, Playford RJ, Furness JB.

Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7318-23.


CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer.

Wicking C, Simms LA, Evans T, Walsh M, Chawengsaksophak K, Beck F, Chenevix-Trench G, Young J, Jass J, Leggett B, Wainwright B.

Oncogene. 1998 Aug 6;17(5):657-9.


Homeosis and intestinal tumours in Cdx2 mutant mice.

Chawengsaksophak K, James R, Hammond VE, Köntgen F, Beck F.

Nature. 1997 Mar 6;386(6620):84-7.


Chromosomal localization of cdx2, a murine homologue of the Drosophila gene caudal, to mouse chromosome 5.

Chawengsaksophak K, Beck F.

Genomics. 1996 Jun 1;34(2):270-1. No abstract available.


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