Sort by
Items per page

Send to

Choose Destination

Search results

Items: 49


Sialochemical analysis in polytraumatized patients in intensive care units.

Chaves MHM, Wolf ARDS, Nascimento KAL, Nawcki D, Feustel GM, Bettega PVC, Ignacio SA, Brancher JA, Tannous LA, Werneck RI, Souza PHC, de Barros MMT, Johann ACBR.

PLoS One. 2019 Oct 3;14(10):e0222974. doi: 10.1371/journal.pone.0222974. eCollection 2019.


New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells.

Garcia IJP, de Oliveira GC, de Moura Valadares JM, Banfi FF, Andrade SN, Freitas TR, Dos Santos Monção Filho E, Lima Santos H, Júnior GMV, Chaves MH, de Jesus Rodrigues D, Sanchez BAM, Varotti FP, Barbosa LA.

Steroids. 2019 Sep 6;152:108490. doi: 10.1016/j.steroids.2019.108490. [Epub ahead of print]


Application of multivariate optimization for the selective extraction of phenolic compounds in cashew nuts (Anacardium occidentale L.).

Mendes MKA, Oliveira CBDS, Veras MDA, Araújo BQ, Dantas C, Chaves MH, Lopes Júnior CA, Vieira EC.

Talanta. 2019 Dec 1;205:120100. doi: 10.1016/j.talanta.2019.06.100. Epub 2019 Jun 29.


Involvement of Potassium Channels, Nitric Oxide Synthase, and Guanylate Cyclase in the Spasmolytic Effect of Simaba ferruginea A.St.-Hil on Rat Isolated Ileum.

Almendra RB, da Fonseca OC, Nunes DB, da Silva TIN, Oliveira JSSM, Chaves MH, de Oliveira AP, Dos Santos RF, Oliveira RCM.

Dig Dis Sci. 2019 Nov;64(11):3104-3114. doi: 10.1007/s10620-019-05667-7. Epub 2019 May 24.


Terminalia fagifolia Mart. & Zucc. elicits vasorelaxation of rat thoracic aorta through nitric oxide and K+ channels dependent mechanism.

de Carvalho EF, Nunes AF, Silva NCB, da Silva Gomes JP, de Sousa RP, Silva VG, Nunes PHM, Santos RF, Chaves MH, Oliveira AP, Oliveira RCM.

Biol Open. 2019 Feb 27;8(2). pii: bio035238. doi: 10.1242/bio.035238.


α, β-Amyrin, a pentacyclic triterpenoid from Protium heptaphyllum suppresses adipocyte differentiation accompanied by down regulation of PPARγ and C/EBPα in 3T3-L1 cells.

de Melo KM, de Oliveira FTB, Costa Silva RA, Gomes Quinderé AL, Marinho Filho JDB, Araújo AJ, Barros Pereira ED, Carvalho AA, Chaves MH, Rao VS, Santos FA.

Biomed Pharmacother. 2019 Jan;109:1860-1866. doi: 10.1016/j.biopha.2018.11.027. Epub 2018 Nov 26.


Silver and gold nanoparticles from tannic acid: synthesis, characterization and evaluation of antileishmanial and cytotoxic activities.

Lopes LCS, Brito LM, Bezerra TT, Gomes KN, Carvalho FAA, Chaves MH, Cantanhêde W.

An Acad Bras Cienc. 2018 Jul-Sep;90(3):2679-2689. doi: 10.1590/0001-3765201820170598. Epub 2018 Jul 19.


Marinobufagin, a molecule from poisonous frogs, causes biochemical, morphological and cell cycle changes in human neoplasms and vegetal cells.

Machado KDC, Sousa LQ, Lima DJB, Soares BM, Cavalcanti BC, Maranhão SS, Noronha JDC, Rodrigues DJ, Militão GCG, Chaves MH, Vieira-Júnior GM, Pessoa C, Moraes MO, Sousa JMCE, Melo-Cavalcante AAC, Ferreira PMP.

Toxicol Lett. 2018 Mar 15;285:121-131. doi: 10.1016/j.toxlet.2017.12.018. Epub 2017 Dec 26.


Platonia insignis Mart., a Brazilian Amazonian Plant: The Stem Barks Extract and Its Main Constituent Lupeol Exert Antileishmanial Effects Involving Macrophages Activation.

Souza AC, Alves MMM, Brito LM, Oliveira LGC, Sobrinho-Júnior EPC, Costa ICG, Freitas SDL, Rodrigues KADF, Chaves MH, Arcanjo DDR, Carvalho FAA.

Evid Based Complement Alternat Med. 2017;2017:3126458. doi: 10.1155/2017/3126458. Epub 2017 Aug 9.


The triterpenoid alpha, beta-amyrin prevents the impaired aortic vascular reactivity in high-fat diet-induced obese mice.

Santos FA, Carvalho KMMB, Batista-Lima FJ, Nunes PIG, Viana AFSC, de Carvalho Almeida da Silva AA, da Cruz Fonseca SG, Chaves MH, Rao VS, Magalhães PJC, de Brito TS.

Naunyn Schmiedebergs Arch Pharmacol. 2017 Oct;390(10):1029-1039. doi: 10.1007/s00210-017-1404-1. Epub 2017 Jul 17.


Gallic and ellagic acids: two natural immunomodulator compounds solve infection of macrophages by Leishmania major.

Alves MMM, Brito LM, Souza AC, Queiroz BCSH, de Carvalho TP, Batista JF, Oliveira JSSM, de Mendonça IL, Lira SRS, Chaves MH, Gonçalves JCR, Carneiro SMP, Arcanjo DDR, Carvalho FAA.

Naunyn Schmiedebergs Arch Pharmacol. 2017 Sep;390(9):893-903. doi: 10.1007/s00210-017-1387-y. Epub 2017 Jun 22.


Antiprotozoal activity of extracts and isolated triterpenoids of 'carnauba' (Copernicia prunifera) wax from Brazil.

de Almeida BC, Araújo BQ, Carvalho AA, Freitas SD, Maciel DD, Ferreira AJ, Tempone AG, Martins LF, Alexandre TR, Chaves MH, Lago JH.

Pharm Biol. 2016 Dec;54(12):3280-3284. Epub 2016 Aug 28.


Inhibitory effects of Zanthoxylum rhoifolium Lam. (Rutaceae) against the infection and infectivity of macrophages by Leishmania amazonensis.

Melo B Neto, Leitão JM, Oliveira LG, Santos SE, Carneiro SM, Rodrigues KA, Chaves MH, Arcanjo DD, Carvalho FA.

An Acad Bras Cienc. 2016;88(3 Suppl):1851-1861. doi: 10.1590/0001-3765201620150131. Epub 2016 Aug 15.


Amyrins from Protium heptaphyllum Reduce High-Fat Diet-Induced Obesity in Mice via Modulation of Enzymatic, Hormonal And Inflammatory Responses.

Carvalho KM, de Melo TS, de Melo KM, Quinderé AL, de Oliveira FT, Viana AF, Nunes PI, Quetz JD, Viana DA, da Silva AA, Havt A, Fonseca SG, Chaves MH, Rao VS, Santos FA.

Planta Med. 2017 Feb;83(3-04):285-291. doi: 10.1055/s-0042-114222. Epub 2016 Aug 15.


Quantification of bufadienolides in the poisons of Rhinella marina and Rhaebo guttatus by HPLC-UV.

Kerkhoff J, Noronha Jda C, Bonfilio R, Sinhorin AP, Rodrigues Dde J, Chaves MH, Vieira GM Júnior.

Toxicon. 2016 Sep 1;119:311-8. doi: 10.1016/j.toxicon.2016.07.003. Epub 2016 Jul 4.


The Resin from Protium heptaphyllum Prevents High-Fat Diet-Induced Obesity in Mice: Scientific Evidence and Potential Mechanisms.

Carvalho KM, Marinho Filho JD, de Melo TS, Araújo AJ, Quetz Jda S, da Cunha Mdo P, de Melo KM, da Silva AA, Tomé AR, Havt A, Fonseca SG, Brito GA, Chaves MH, Rao VS, Santos FA.

Evid Based Complement Alternat Med. 2015;2015:106157. doi: 10.1155/2015/106157. Epub 2015 Jan 29.


Pharmacological evidence of α2-adrenergic receptors in the hypotensive effect of Platonia insignis mart.

Mendes MB, da Silva-Filho JC, Sabino CK, Arcanjo DD, Sousa CM, Costa IC, Chaves MH, Oliveira Rde C, Oliveira AP.

J Med Food. 2014 Oct;17(10):1079-85. doi: 10.1089/jmf.2013.0151. Epub 2014 Jul 23.


Gastric antiulcerogenic and hypokinetic activities of Terminalia fagifolia Mart. & Zucc. (Combretaceae).

Nunes PH, Martins Mdo C, Oliveira Rde C, Chaves MH, Sousa EA, Leite JR, Véras LM, Almeida FR.

Biomed Res Int. 2014;2014:261745. doi: 10.1155/2014/261745. Epub 2014 May 12.


Anti-inflammatory and antinociceptive effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in rodents.

Silva FV, Oliveira IS, Figueiredo KA, Júnior FB, Costa DA, Chaves MH, Amaral MP, Almeida FR, Oliveira FA, Oliveira RC.

J Med Food. 2014 Jun;17(6):694-700. doi: 10.1089/jmf.2013.0062. Epub 2014 Jan 29.


Antihypertensive and vasorelaxant effects of ethanol extract of stem barks from Zanthoxylum rhoifolium Lam. in rats.

Ferreira-Filho ES, Arcanjo DD, Moura LH, da Silva-Filho JC, Paulino ET, Ribeiro EA, Chaves MH, Oliveira Rde C, de Oliveira AP.

Indian J Exp Biol. 2013 Aug;51(8):661-9.


Gastroprotective activity of Cenostigma macrophyllum Tul. var. acuminata Teles Freire leaves on experimental ulcer models.

Viana AF, Fernandes HB, Silva FV, Oliveira IS, Freitas FF, Machado FD, Costa CL, Arcanjo DD, Chaves MH, Oliveira FA, Oliveira RC.

J Ethnopharmacol. 2013 Oct 28;150(1):316-23. doi: 10.1016/j.jep.2013.08.047. Epub 2013 Sep 12.


The stem bark extracts of Cenostigma macrophyllum attenuates tactile allodynia in streptozotocin-induced diabetic rats.

Piaulino CA, Carvalho FC, Almeida BC, Chaves MH, Almeida FR, Brito SM.

Pharm Biol. 2013 Oct;51(10):1243-8. doi: 10.3109/13880209.2013.786096. Epub 2013 Jul 11.


Chemical constituents and cytotoxic evaluation of essential oils from leaves of Porcelia macrocarpa (Annonaceae).

da Silva EB, Matsuo AL, Figueiredo CR, Chaves MH, Sartorelli P, Lago JH.

Nat Prod Commun. 2013 Feb;8(2):277-9.


Antinociceptive effect of Lecythis pisonis Camb. (Lecythidaceae) in models of acute pain in mice.

Brandão MS, Pereira SS, Lima DF, Oliveira JP, Ferreira EL, Chaves MH, Almeida FR.

J Ethnopharmacol. 2013 Mar 7;146(1):180-6. doi: 10.1016/j.jep.2012.12.028. Epub 2012 Dec 28.


The cytotoxic and antileishmanial activity of extracts and fractions of leaves and fruits of Azadirachta indica (A Juss.).

Carneiro SM, Carvalho FA, Santana LC, Sousa AP, Neto JM, Chaves MH.

Biol Res. 2012;45(2):111-6. doi: 10.4067/S0716-97602012000200002.


Antihyperglycemic and hypolipidemic effects of α, β-amyrin, a triterpenoid mixture from Protium heptaphyllum in mice.

Santos FA, Frota JT, Arruda BR, de Melo TS, da Silva AA, Brito GA, Chaves MH, Rao VS.

Lipids Health Dis. 2012 Aug 6;11:98. doi: 10.1186/1476-511X-11-98.


Mechanisms of the antinociceptive action of (-) epicatechin obtained from the hydroalcoholic fraction of Combretum leprosum Mart & Eic in rodents.

Lopes Lda S, Marques RB, Fernandes HB, Pereira Sda S, Ayres MC, Chaves MH, Almeida FR.

J Biomed Sci. 2012 Jul 25;19:68. doi: 10.1186/1423-0127-19-68.


Gastroprotective activity of Sterculia striata A. St. Hil. & Naudin (Malvaceae) in rodents.

Sousa JA, Oliveira IS, Silva FV, Costa DA, Chaves MH, Oliveira FA, Nunes PH, Oliveira RC.

Z Naturforsch C J Biosci. 2012 Mar-Apr;67(3-4):163-71.


Effects of Lecythis pisonis Camb. (Lecythidaceae) in a mouse model of pruritus.

Silva LL, Gomes BS, Sousa-Neto BP, Oliveira JP, Ferreira EL, Chaves MH, Oliveira FA.

J Ethnopharmacol. 2012 Jan 6;139(1):90-7. doi: 10.1016/j.jep.2011.10.023. Epub 2011 Oct 28.


Gastroprotective activity of Zanthoxylum rhoifolium Lam. in animal models.

Freitas FF, Fernandes HB, Piauilino CA, Pereira SS, Carvalho KI, Chaves MH, Soares PM, Miura LM, Leite JR, Oliveira RC, Oliveira FA.

J Ethnopharmacol. 2011 Sep 1;137(1):700-8. doi: 10.1016/j.jep.2011.06.026. Epub 2011 Jun 22.


Anti-inflammatory effect of α,β-amyrin, a triterpene from Protium heptaphyllum, on cerulein-induced acute pancreatitis in mice.

Melo CM, Morais TC, Tomé AR, Brito GA, Chaves MH, Rao VS, Santos FA.

Inflamm Res. 2011 Jul;60(7):673-81. doi: 10.1007/s00011-011-0321-x. Epub 2011 Mar 12.


Antinociceptive effect on mice of the hydroalcoholic fraction and (-) epicatechin obtained from Combretum leprosum Mart & Eich.

Lopes LS, Marques RB, Pereira SS, Ayres MC, Chaves MH, Cavalheiro AJ, Vieira Júnior GM, Almeida FR.

Braz J Med Biol Res. 2010 Dec;43(12):1184-92.


alpha,beta-amyrin, a natural triterpenoid ameliorates L-arginine-induced acute pancreatitis in rats.

Melo CM, Carvalho KM, Neves JC, Morais TC, Rao VS, Santos FA, Brito GA, Chaves MH.

World J Gastroenterol. 2010 Sep 14;16(34):4272-80.


Antinociceptive effect of Zanthoxylum rhoifolium Lam. (Rutaceae) in models of acute pain in rodents.

Pereira SS, Lopes LS, Marques RB, Figueiredo KA, Costa DA, Chaves MH, Almeida FR.

J Ethnopharmacol. 2010 May 27;129(2):227-31. doi: 10.1016/j.jep.2010.03.009. Epub 2010 Mar 19.


Gastroprotective effect of the ethanolic extract of Parkia platycephala Benth. leaves against acute gastric lesion models in rodents.

Fernandes HB, Silva FV, Passos FF, Bezerra RD, Chaves MH, Oliveira FA, Oliveira RC.

Biol Res. 2010;43(4):451-7. doi: /S0716-97602010000400010. Epub 2011 Feb 1.


Gastroprotective effect of lupeol on ethanol-induced gastric damage and the underlying mechanism.

Lira SR, Rao VS, Carvalho AC, Guedes MM, de Morais TC, de Souza AL, Trevisan MT, Lima AF, Chaves MH, Santos FA.

Inflammopharmacology. 2009 Aug;17(4):221-8. doi: 10.1007/s10787-009-0009-9. Epub 2009 Jul 16.


Catalysts of Cu(II) and Co(II) ions adsorbed in chitosan used in transesterification of soy bean and babassu oils - a new route for biodiesel syntheses.

da Silva RB, Lima Neto AF, Soares Dos Santos LS, de Oliveira Lima JR, Chaves MH, Dos Santos JR Jr, de Lima GM, de Moura EM, de Moura CV.

Bioresour Technol. 2008 Oct;99(15):6793-8. doi: 10.1016/j.biortech.2008.01.047. Epub 2008 Apr 28.


Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels.

Lima-Júnior RC, Sousa DI, Brito GA, Cunha GM, Chaves MH, Rao VS, Santos FA.

Inflamm Res. 2007 Dec;56(12):487-94. doi: 10.1007/s00011-007-7023-4.


Antinoceptive effect of triterpenoid alpha,beta-amyrin in rats on orofacial pain induced by formalin and capsaicin.

Holanda Pinto SA, Pinto LM, Guedes MA, Cunha GM, Chaves MH, Santos FA, Rao VS.

Phytomedicine. 2008 Aug;15(8):630-4. doi: 10.1016/j.phymed.2007.11.016. Epub 2008 Mar 4.


Anti-inflammatory effect of alpha, beta-Amyrin, a pentacyclic triterpene from Protium heptaphyllum in rat model of acute periodontitis.

Holanda Pinto SA, Pinto LM, Cunha GM, Chaves MH, Santos FA, Rao VS.

Inflammopharmacology. 2008 Feb;16(1):48-52.


Evaluation of antifungal and DNA-damaging activities of alkaloids from branches of Porcelia macrocarpa.

Lago JH, Chaves MH, Ayres MC, Agripino DG, Young MC.

Planta Med. 2007 Mar;73(3):292-5. Epub 2007 Mar 12.


Attenuation of visceral nociception by alpha- and beta-amyrin, a triterpenoid mixture isolated from the resin of Protium heptaphyllum, in mice.

Lima-Júnior RC, Oliveira FA, Gurgel LA, Cavalcante IJ, Santos KA, Campos DA, Vale CA, Silva RM, Chaves MH, Rao VS, Santos FA.

Planta Med. 2006 Jan;72(1):34-9.


Attenuation of capsaicin-induced acute and visceral nociceptive pain by alpha- and beta-amyrin, a triterpene mixture isolated from Protium heptaphyllum resin in mice.

Oliveira FA, Costa CL, Chaves MH, Almeida FR, Cavalcante IJ, Lima AF, Lima RC Jr, Silva RM, Campos AR, Santos FA, Rao VS.

Life Sci. 2005 Oct 21;77(23):2942-52. Epub 2005 Jun 16.


Protective effect of alpha- and beta-amyrin, a triterpene mixture from Protium heptaphyllum (Aubl.) March. trunk wood resin, against acetaminophen-induced liver injury in mice.

Oliveira FA, Chaves MH, Almeida FR, Lima RC Jr, Silva RM, Maia JL, Brito GA, Santos FA, Rao VS.

J Ethnopharmacol. 2005 Apr 8;98(1-2):103-8.


Evaluation of a methylation procedure to determine cyclopropenoids fatty acids from Sterculia striata St. Hil. Et Nauds seed oil.

Aued-Pimentel S, Lago JH, Chaves MH, Kumagai EE.

J Chromatogr A. 2004 Oct 29;1054(1-2):235-9.


Gastroprotective effect of the mixture of alpha- and beta-amyrin from Protium heptaphyllum: role of capsaicin-sensitive primary afferent neurons.

Oliveira FA, Vieira-Júnior GM, Chaves MH, Almeida FR, Santos KA, Martins FS, Silva RM, Santos FA, Rao VS.

Planta Med. 2004 Aug;70(8):780-2.


Pentacyclic triterpenoids, alpha,beta-amyrins, suppress the scratching behavior in a mouse model of pruritus.

Oliveira FA, Lima-Junior RC, Cordeiro WM, Vieira-Júnior GM, Chaves MH, Almeida FR, Silva RM, Santos FA, Rao VS.

Pharmacol Biochem Behav. 2004 Aug;78(4):719-25.


Gastroprotective and anti-inflammatory effects of resin from Protium heptaphyllum in mice and rats.

Oliveira FA, Vieira-Júnior GM, Chaves MH, Almeida FR, Florêncio MG, Lima RC Jr, Silva RM, Santos FA, Rao VS.

Pharmacol Res. 2004 Feb;49(2):105-11.


Alkaloids from Porcelia macrocarpa.

Chaves MH, Santos LA, Lago JH, Roque NF.

J Nat Prod. 2001 Feb;64(2):240-2.


Supplemental Content

Loading ...
Support Center