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Items: 11

1.

A selective class of inhibitors for the CLC-Ka chloride ion channel.

Koster AK, Wood CAP, Thomas-Tran R, Chavan TS, Almqvist J, Choi KH, Du Bois J, Maduke M.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4900-E4909. doi: 10.1073/pnas.1720584115. Epub 2018 Apr 18.

2.

Plasma membrane regulates Ras signaling networks.

Chavan TS, Muratcioglu S, Marszalek R, Jang H, Keskin O, Gursoy A, Nussinov R, Gaponenko V.

Cell Logist. 2016 Feb 18;5(4):e1136374. eCollection 2015 Oct-Dec. Review.

3.

Revealing an outward-facing open conformational state in a CLC Cl(-)/H(+) exchange transporter.

Khantwal CM, Abraham SJ, Han W, Jiang T, Chavan TS, Cheng RC, Elvington SM, Liu CW, Mathews II, Stein RA, Mchaourab HS, Tajkhorshid E, Maduke M.

Elife. 2016 Jan 22;5. pii: e11189. doi: 10.7554/eLife.11189.

4.

The higher level of complexity of K-Ras4B activation at the membrane.

Jang H, Banerjee A, Chavan TS, Lu S, Zhang J, Gaponenko V, Nussinov R.

FASEB J. 2016 Apr;30(4):1643-55. doi: 10.1096/fj.15-279091. Epub 2015 Dec 30.

5.

High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site.

Chavan TS, Jang H, Khavrutskii L, Abraham SJ, Banerjee A, Freed BC, Johannessen L, Tarasov SG, Gaponenko V, Nussinov R, Tarasova NI.

Biophys J. 2015 Dec 15;109(12):2602-2613. doi: 10.1016/j.bpj.2015.09.034.

6.

GTP-Dependent K-Ras Dimerization.

Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R.

Structure. 2015 Jul 7;23(7):1325-35. doi: 10.1016/j.str.2015.04.019. Epub 2015 Jun 4.

7.

Heteromerization of chemokine (C-X-C motif) receptor 4 with α1A/B-adrenergic receptors controls α1-adrenergic receptor function.

Tripathi A, Vana PG, Chavan TS, Brueggemann LI, Byron KL, Tarasova NI, Volkman BF, Gaponenko V, Majetschak M.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1659-68. doi: 10.1073/pnas.1417564112. Epub 2015 Mar 16.

8.

Mechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.

Jang H, Abraham SJ, Chavan TS, Hitchinson B, Khavrutskii L, Tarasova NI, Nussinov R, Gaponenko V.

J Biol Chem. 2015 Apr 10;290(15):9465-77. doi: 10.1074/jbc.M114.620724. Epub 2015 Feb 24.

9.

A novel method for the production of fully modified K-Ras 4B.

Chavan TS, Meyer JO, Chisholm L, Dobosz-Bartoszek M, Gaponenko V.

Methods Mol Biol. 2014;1120:19-32. doi: 10.1007/978-1-62703-791-4_2.

PMID:
24470016
10.

Application of reductive ¹³C-methylation of lysines to enhance the sensitivity of conventional NMR methods.

Chavan TS, Abraham S, Gaponenko V.

Molecules. 2013 Jun 18;18(6):7103-19. doi: 10.3390/molecules18067103.

11.

ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors.

Halasi M, Wang M, Chavan TS, Gaponenko V, Hay N, Gartel AL.

Biochem J. 2013 Sep 1;454(2):201-8. doi: 10.1042/BJ20130282.

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