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Items: 50


Transcriptional alterations in glioma result primarily from DNA methylation-independent mechanisms.

Court F, Le Boiteux E, Fogli A, Müller-Barthélémy M, Vaurs-Barrière C, Chautard E, Pereira B, Biau J, Kemeny JL, Khalil T, Karayan-Tapon L, Verrelle P, Arnaud P.

Genome Res. 2019 Oct;29(10):1605-1621. doi: 10.1101/gr.249219.119. Epub 2019 Sep 18.


Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models.

Biau J, Chautard E, Berthault N, de Koning L, Court F, Pereira B, Verrelle P, Dutreix M.

Front Oncol. 2019 Jun 19;9:549. doi: 10.3389/fonc.2019.00549. eCollection 2019.


WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma.

Gonçalves CS, Vieira de Castro J, Pojo M, Martins EP, Queirós S, Chautard E, Taipa R, Pires MM, Pinto AA, Pardal F, Custódia C, Faria CC, Clara C, Reis RM, Sousa N, Costa BM.

Theranostics. 2018 Sep 9;8(17):4805-4823. doi: 10.7150/thno.25025. eCollection 2018.


Second course of stereotactic radiosurgery for locally recurrent brain metastases: Safety and efficacy.

Moreau J, Khalil T, Dupic G, Chautard E, Lemaire JJ, Magnier F, Dedieu V, Lapeyre M, Verrelle P, Biau J.

PLoS One. 2018 Apr 5;13(4):e0195608. doi: 10.1371/journal.pone.0195608. eCollection 2018.


Complementarity of assembly-first and mapping-first approaches for alternative splicing annotation and differential analysis from RNAseq data.

Benoit-Pilven C, Marchet C, Chautard E, Lima L, Lambert MP, Sacomoto G, Rey A, Cologne A, Terrone S, Dulaurier L, Claude JB, Bourgeois CF, Auboeuf D, Lacroix V.

Sci Rep. 2018 Mar 9;8(1):4307. doi: 10.1038/s41598-018-21770-7.


Radiotherapy plus temozolomide in elderly patients with glioblastoma: a "real-life" report.

Biau J, Chautard E, De Schlichting E, Dupic G, Pereira B, Fogli A, Müller-Barthélémy M, Dalloz P, Khalil T, Dillies AF, Durando X, Godfraind C, Verrelle P.

Radiat Oncol. 2017 Dec 6;12(1):197. doi: 10.1186/s13014-017-0929-2.


Detection of the alternative lengthening of telomeres pathway in malignant gliomas for improved molecular diagnosis.

Fogli A, Demattei MV, Corset L, Vaurs-Barrière C, Chautard E, Biau J, Kémény JL, Godfraind C, Pereira B, Khalil T, Grandin N, Arnaud P, Charbonneau M, Verrelle P.

J Neurooncol. 2017 Nov;135(2):381-390. doi: 10.1007/s11060-017-2585-7. Epub 2017 Jul 28.


Predictive biomarkers of resistance to hypofractionated radiotherapy in high grade glioma.

Biau J, Chautard E, De Koning L, Court F, Pereira B, Verrelle P, Dutreix M.

Radiat Oncol. 2017 Jul 28;12(1):123. doi: 10.1186/s13014-017-0858-0.


Identification of protein features encoded by alternative exons using Exon Ontology.

Tranchevent LC, Aubé F, Dulaurier L, Benoit-Pilven C, Rey A, Poret A, Chautard E, Mortada H, Desmet FO, Chakrama FZ, Moreno-Garcia MA, Goillot E, Janczarski S, Mortreux F, Bourgeois CF, Auboeuf D.

Genome Res. 2017 Jun;27(6):1087-1097. doi: 10.1101/gr.212696.116. Epub 2017 Apr 18.


Role of STAT3 in Genesis and Progression of Human Malignant Gliomas.

Ouédraogo ZG, Biau J, Kemeny JL, Morel L, Verrelle P, Chautard E.

Mol Neurobiol. 2017 Oct;54(8):5780-5797. doi: 10.1007/s12035-016-0103-0. Epub 2016 Sep 22. Review.


Global Conservation of Protein Status between Cell Lines and Xenografts.

Biau J, Chautard E, Court F, Pereira B, Verrelle P, Devun F, De Koning L, Dutreix M.

Transl Oncol. 2016 Aug;9(4):313-21. doi: 10.1016/j.tranon.2016.05.005.


Nucleosome eviction in mitosis assists condensin loading and chromosome condensation.

Toselli-Mollereau E, Robellet X, Fauque L, Lemaire S, Schiklenk C, Klein C, Hocquet C, Legros P, N'Guyen L, Mouillard L, Chautard E, Auboeuf D, Haering CH, Bernard P.

EMBO J. 2016 Jul 15;35(14):1565-81. doi: 10.15252/embj.201592849. Epub 2016 Jun 6.


Different dose rate-dependent responses of human melanoma cells and fibroblasts to low dose fast neutrons.

Dionet C, Müller-Barthélémy M, Marceau G, Denis JM, Averbeck D, Gueulette J, Sapin V, Pereira B, Tchirkov A, Chautard E, Verrelle P.

Int J Radiat Biol. 2016 Sep;92(9):527-35. doi: 10.1080/09553002.2016.1186300. Epub 2016 Jun 3.


Fractionated stereotactic radiotherapy of benign skull-base tumors: a dosimetric comparison of volumetric modulated arc therapy with Rapidarc® versus non-coplanar dynamic arcs.

Martin F, Magnier F, Berger L, Miroir J, Chautard E, Verrelle P, Lapeyre M, Biau J.

Radiat Oncol. 2016 Apr 18;11:58. doi: 10.1186/s13014-016-0632-8.


Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

Freyermuth F, Rau F, Kokunai Y, Linke T, Sellier C, Nakamori M, Kino Y, Arandel L, Jollet A, Thibault C, Philipps M, Vicaire S, Jost B, Udd B, Day JW, Duboc D, Wahbi K, Matsumura T, Fujimura H, Mochizuki H, Deryckere F, Kimura T, Nukina N, Ishiura S, Lacroix V, Campan-Fournier A, Navratil V, Chautard E, Auboeuf D, Horie M, Imoto K, Lee KY, Swanson MS, de Munain AL, Inada S, Itoh H, Nakazawa K, Ashihara T, Wang E, Zimmer T, Furling D, Takahashi MP, Charlet-Berguerand N.

Nat Commun. 2016 Apr 11;7:11067. doi: 10.1038/ncomms11067.


Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents.

Merlevede J, Droin N, Qin T, Meldi K, Yoshida K, Morabito M, Chautard E, Auboeuf D, Fenaux P, Braun T, Itzykson R, de Botton S, Quesnel B, Commes T, Jourdan E, Vainchenker W, Bernard O, Pata-Merci N, Solier S, Gayevskiy V, Dinger ME, Cowley MJ, Selimoglu-Buet D, Meyer V, Artiguenave F, Deleuze JF, Preudhomme C, Stratton MR, Alexandrov LB, Padron E, Ogawa S, Koscielny S, Figueroa M, Solary E.

Nat Commun. 2016 Feb 24;7:10767. doi: 10.1038/ncomms10767.


The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients' survival.

Fogli A, Chautard E, Vaurs-Barrière C, Pereira B, Müller-Barthélémy M, Court F, Biau J, Pinto AA, Kémény JL, Khalil T, Karayan-Tapon L, Verrelle P, Costa BM, Arnaud P.

Carcinogenesis. 2016 Feb;37(2):169-176. doi: 10.1093/carcin/bgv251. Epub 2015 Dec 30.


Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound.

Merle P, Gueugneau M, Teulade-Fichou MP, Müller-Barthélémy M, Amiard S, Chautard E, Guetta C, Dedieu V, Communal Y, Mergny JL, Gallego M, White C, Verrelle P, Tchirkov A.

Sci Rep. 2015 Nov 6;5:16255. doi: 10.1038/srep16255.


In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin.

Laustriat D, Gide J, Barrault L, Chautard E, Benoit C, Auboeuf D, Boland A, Battail C, Artiguenave F, Deleuze JF, Bénit P, Rustin P, Franc S, Charpentier G, Furling D, Bassez G, Nissan X, Martinat C, Peschanski M, Baghdoyan S.

Mol Ther Nucleic Acids. 2015 Nov 3;4:e262. doi: 10.1038/mtna.2015.35.


[Radioresistance parameters in head and neck cancers and methods to radiosensitize].

Biau J, Chautard E, Miroir J, Lapeyre M.

Cancer Radiother. 2015 Aug;19(5):337-46; quiz 360-1, 363. doi: 10.1016/j.canrad.2015.02.014. Epub 2015 Jun 25. Review. French.


STAT3 Serine 727 Phosphorylation: A Relevant Target to Radiosensitize Human Glioblastoma.

Ouédraogo ZG, Müller-Barthélémy M, Kemeny JL, Dedieu V, Biau J, Khalil T, Raoelfils LI, Granzotto A, Pereira B, Beaudoin C, Guissou IP, Berger M, Morel L, Chautard E, Verrelle P.

Brain Pathol. 2016 Jan;26(1):18-30. doi: 10.1111/bpa.12254. Epub 2015 Apr 30.


[Elderly patients with glioblastoma: state of the art].

Biau J, Dalloz P, Durando X, Hager MO, Ouédraogo ZG, Khalil T, Lemaire JJ, Chautard E, Verrelle P.

Bull Cancer. 2015 Mar;102(3):277-86. doi: 10.1016/j.bulcan.2015.02.002. Epub 2015 Feb 27. Review. French.


Cellular and molecular portrait of eleven human glioblastoma cell lines under photon and carbon ion irradiation.

Ferrandon S, Magné N, Battiston-Montagne P, Hau-Desbat NH, Diaz O, Beuve M, Constanzo J, Chargari C, Poncet D, Chautard E, Ardail D, Alphonse G, Rodriguez-Lafrasse C.

Cancer Lett. 2015 Apr 28;360(1):10-6. doi: 10.1016/j.canlet.2015.01.025. Epub 2015 Feb 2.


A preclinical study combining the DNA repair inhibitor Dbait with radiotherapy for the treatment of melanoma.

Biau J, Devun F, Jdey W, Kotula E, Quanz M, Chautard E, Sayarath M, Sun JS, Verrelle P, Dutreix M.

Neoplasia. 2014 Oct 23;16(10):835-44. doi: 10.1016/j.neo.2014.08.008. eCollection 2014 Oct.


New in-capillary electrophoretic kinase assays to evaluate inhibitors of the PI3k/Akt/mTOR signaling pathway.

Nehmé R, Nehmé H, Saurat T, de-Tauzia ML, Buron F, Lafite P, Verrelle P, Chautard E, Morin P, Routier S, Bénédetti H.

Anal Bioanal Chem. 2014 Jun;406(15):3743-54. doi: 10.1007/s00216-014-7790-z. Epub 2014 May 11.


Role of Akt in human malignant glioma: from oncogenesis to tumor aggressiveness.

Chautard E, Ouédraogo ZG, Biau J, Verrelle P.

J Neurooncol. 2014 Apr;117(2):205-15. doi: 10.1007/s11060-014-1382-9. Epub 2014 Jan 30. Review.


Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin.

Mallinjoud P, Villemin JP, Mortada H, Polay Espinoza M, Desmet FO, Samaan S, Chautard E, Tranchevent LC, Auboeuf D.

Genome Res. 2014 Mar;24(3):511-21. doi: 10.1101/gr.162933.113. Epub 2013 Dec 4.


Extended interaction network of procollagen C-proteinase enhancer-1 in the extracellular matrix.

Salza R, Peysselon F, Chautard E, Faye C, Moschcovich L, Weiss T, Perrin-Cocon L, Lotteau V, Kessler E, Ricard-Blum S.

Biochem J. 2014 Jan 1;457(1):137-49. doi: 10.1042/BJ20130295.


Mapping of heparin/heparan sulfate binding sites on αvβ3 integrin by molecular docking.

Ballut L, Sapay N, Chautard E, Imberty A, Ricard-Blum S.

J Mol Recognit. 2013 Feb;26(2):76-85. doi: 10.1002/jmr.2250.


Protein interaction data curation: the International Molecular Exchange (IMEx) consortium.

Orchard S, Kerrien S, Abbani S, Aranda B, Bhate J, Bidwell S, Bridge A, Briganti L, Brinkman FS, Cesareni G, Chatr-aryamontri A, Chautard E, Chen C, Dumousseau M, Goll J, Hancock RE, Hannick LI, Jurisica I, Khadake J, Lynn DJ, Mahadevan U, Perfetto L, Raghunath A, Ricard-Blum S, Roechert B, Salwinski L, Stümpflen V, Tyers M, Uetz P, Xenarios I, Hermjakob H.

Nat Methods. 2012 Apr;9(4):345-50. doi: 10.1038/nmeth.1931. Erratum in: Nat Methods. 2012 Jun;9(6):626. Brinkman, Fiona [corrected to Brinkman, Fiona S L]; Hancock, Robert [corrected to Hancock, Robert E W].


Toward a systems level view of the ECM and related proteins: a framework for the systematic definition and analysis of biological systems.

Cromar GL, Xiong X, Chautard E, Ricard-Blum S, Parkinson J.

Proteins. 2012 Jun;80(6):1522-44. doi: 10.1002/prot.24036. Epub 2012 Feb 13. Erratum in: Proteins. 2012 Nov;80(11):2643.


Telomere targeting with a new G4 ligand enhances radiation-induced killing of human glioblastoma cells.

Merle P, Evrard B, Petitjean A, Lehn JM, Teulade-Fichou MP, Chautard E, De Cian A, Guittat L, Tran PL, Mergny JL, Verrelle P, Tchirkov A.

Mol Cancer Ther. 2011 Oct;10(10):1784-95. doi: 10.1158/1535-7163.MCT-10-0664.


PSICQUIC and PSISCORE: accessing and scoring molecular interactions.

Aranda B, Blankenburg H, Kerrien S, Brinkman FS, Ceol A, Chautard E, Dana JM, De Las Rivas J, Dumousseau M, Galeota E, Gaulton A, Goll J, Hancock RE, Isserlin R, Jimenez RC, Kerssemakers J, Khadake J, Lynn DJ, Michaut M, O'Kelly G, Ono K, Orchard S, Prieto C, Razick S, Rigina O, Salwinski L, Simonovic M, Velankar S, Winter A, Wu G, Bader GD, Cesareni G, Donaldson IM, Eisenberg D, Kleywegt GJ, Overington J, Ricard-Blum S, Tyers M, Albrecht M, Hermjakob H.

Nat Methods. 2011 Jun 29;8(7):528-9. doi: 10.1038/nmeth.1637. No abstract available.


MatrixDB, the extracellular matrix interaction database.

Chautard E, Fatoux-Ardore M, Ballut L, Thierry-Mieg N, Ricard-Blum S.

Nucleic Acids Res. 2011 Jan;39(Database issue):D235-40. doi: 10.1093/nar/gkq830. Epub 2010 Sep 17.


Increased expression of the oncogenic KLF6-SV1 transcript in human glioblastoma.

Tchirkov A, Sapin V, Marceau G, Chautard E, Narla G, Veronese L, Friedman S, Khalil T, Vago P, Kemeny JL, Verrelle P.

Clin Chem Lab Med. 2010 Aug;48(8):1167-70. doi: 10.1515/CCLM.2010.219.


Akt signaling pathway: a target for radiosensitizing human malignant glioma.

Chautard E, Loubeau G, Tchirkov A, Chassagne J, Vermot-Desroches C, Morel L, Verrelle P.

Neuro Oncol. 2010 May;12(5):434-43. doi: 10.1093/neuonc/nop059. Epub 2010 Feb 4.


Interaction networks as a tool to investigate the mechanisms of aging.

Chautard E, Thierry-Mieg N, Ricard-Blum S.

Biogerontology. 2010 Aug;11(4):463-73. doi: 10.1007/s10522-010-9268-5. Epub 2010 Mar 7.


The first draft of the endostatin interaction network.

Faye C, Chautard E, Olsen BR, Ricard-Blum S.

J Biol Chem. 2009 Aug 14;284(33):22041-7. doi: 10.1074/jbc.M109.002964. Epub 2009 Jun 19.


Molecular interplay between endostatin, integrins, and heparan sulfate.

Faye C, Moreau C, Chautard E, Jetne R, Fukai N, Ruggiero F, Humphries MJ, Olsen BR, Ricard-Blum S.

J Biol Chem. 2009 Aug 14;284(33):22029-40. doi: 10.1074/jbc.M109.002840. Epub 2009 Jun 5.


Strong correlation between VEGF and MCL-1 mRNA expression levels in B-cell chronic lymphocytic leukemia.

Véronèse L, Tournilhac O, Verrelle P, Davi F, Dighiero G, Chautard E, Veyrat-Masson R, Kwiatkowski F, Goumy C, Gouas L, Bay JO, Vago P, Tchirkov A.

Leuk Res. 2009 Dec;33(12):1623-6. doi: 10.1016/j.leukres.2009.05.003. Epub 2009 May 31.


MatrixDB, a database focused on extracellular protein-protein and protein-carbohydrate interactions.

Chautard E, Ballut L, Thierry-Mieg N, Ricard-Blum S.

Bioinformatics. 2009 Mar 1;25(5):690-1. doi: 10.1093/bioinformatics/btp025. Epub 2009 Jan 15.


Interaction networks: from protein functions to drug discovery. A review.

Chautard E, Thierry-Mieg N, Ricard-Blum S.

Pathol Biol (Paris). 2009 Jun;57(4):324-33. doi: 10.1016/j.patbio.2008.10.004. Epub 2008 Dec 13. Review.


Low MCL-1 mRNA expression correlates with prolonged survival in B-cell chronic lymphocytic leukemia.

Véronèse L, Tournilhac O, Verrelle P, Davi F, Dighiero G, Chautard E, Veyrat-Masson R, Kwiatkowski F, Goumy C, Vago P, Travade P, Tchirkov A.

Leukemia. 2008 Jun;22(6):1291-3. Epub 2007 Nov 29. No abstract available.


Interleukin-6 gene amplification and shortened survival in glioblastoma patients.

Tchirkov A, Khalil T, Chautard E, Mokhtari K, Véronèse L, Irthum B, Vago P, Kémény JL, Verrelle P.

Br J Cancer. 2007 Feb 12;96(3):474-6. Epub 2007 Jan 16.


The Poland syndrome-clinical and genealogical data, dermatoglyphic analysis, and incidence.

Freire-Maia N, Chautard EA, Opitz JM, Freire-Maia A, Quelce-Salgado A.

Hum Hered. 1973;23(2):97-104. No abstract available.


Poland's syndrome.

Chautard EA, Freire-Maia N.

Br Med J. 1971 Dec 25;4(5790):812. No abstract available.


Dermatoglyphic analysis in a highly mutilating syndrome.

Chautard EA, Freire-Maia N.

Acta Genet Med Gemellol (Roma). 1970 Jul;19(3):421-4. No abstract available.


A new malformation syndrome?

Freire-Maia N, Cat I, Lopes VL, Chautard EA, Marcallo FA, Cavalli IJ, Pilotto RF, Schetino MC, Bedrossian AA der.

Lancet. 1970 Apr 18;1(7651):840-1. No abstract available.


A genetic study on palatolabial defects.

Arce-Gomez B, Azevedo JB, Chautard EA, Freire-Maia N.

Hum Hered. 1970;20(6):580-9. No abstract available.


[Incidence and recurrence risks of labiopalatine clefts].

Arce B, Azevedo JB, Freire-Maia N, Chautard EA.

Rev Paul Med. 1968 May;72(5):239-46. Portuguese. No abstract available.


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