Sort by
Items per page

Send to

Choose Destination

Search results

Items: 10


Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1.

He M, Chaurushiya MS, Webster JD, Kummerfeld S, Reja R, Chaudhuri S, Chen YJ, Modrusan Z, Haley B, Dugger DL, Eastham-Anderson J, Lau S, Dey A, Caothien R, Roose-Girma M, Newton K, Dixit VM.

Science. 2019 Apr 19;364(6437):283-285. doi: 10.1126/science.aav4902. Epub 2019 Apr 18.


The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma.

Webster JD, Pham TH, Wu X, Hughes NW, Li Z, Totpal K, Lee HJ, Calses PC, Chaurushiya MS, Stawiski EW, Modrusan Z, Chang MT, Tran C, Lee WP, Chalasani S, Hung J, Sharma N, Chan S, Hotzel K, Talevich E, Shain A, Xu M, Lill J, Dixit VM, Bastian BC, Dey A.

Pigment Cell Melanoma Res. 2019 Mar;32(2):269-279. doi: 10.1111/pcmr.12735. Epub 2018 Sep 24.


Loss of the tumor suppressor BAP1 causes myeloid transformation.

Dey A, Seshasayee D, Noubade R, French DM, Liu J, Chaurushiya MS, Kirkpatrick DS, Pham VC, Lill JR, Bakalarski CE, Wu J, Phu L, Katavolos P, LaFave LM, Abdel-Wahab O, Modrusan Z, Seshagiri S, Dong K, Lin Z, Balazs M, Suriben R, Newton K, Hymowitz S, Garcia-Manero G, Martin F, Levine RL, Dixit VM.

Science. 2012 Sep 21;337(6101):1541-6. Epub 2012 Aug 9.


Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain.

Chaurushiya MS, Lilley CE, Aslanian A, Meisenhelder J, Scott DC, Landry S, Ticau S, Boutell C, Yates JR 3rd, Schulman BA, Hunter T, Weitzman MD.

Mol Cell. 2012 Apr 13;46(1):79-90. doi: 10.1016/j.molcel.2012.02.004. Epub 2012 Mar 7.


The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0.

Lilley CE, Chaurushiya MS, Boutell C, Everett RD, Weitzman MD.

PLoS Pathog. 2011 Jun;7(6):e1002084. doi: 10.1371/journal.ppat.1002084. Epub 2011 Jun 16.


Changing the ubiquitin landscape during viral manipulation of the DNA damage response.

Weitzman MD, Lilley CE, Chaurushiya MS.

FEBS Lett. 2011 Sep 16;585(18):2897-906. doi: 10.1016/j.febslet.2011.04.049. Epub 2011 May 5. Review.


Genomes in conflict: maintaining genome integrity during virus infection.

Weitzman MD, Lilley CE, Chaurushiya MS.

Annu Rev Microbiol. 2010;64:61-81. doi: 10.1146/annurev.micro.112408.134016. Review.


A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses.

Lilley CE, Chaurushiya MS, Boutell C, Landry S, Suh J, Panier S, Everett RD, Stewart GS, Durocher D, Weitzman MD.

EMBO J. 2010 Mar 3;29(5):943-55. doi: 10.1038/emboj.2009.400. Epub 2010 Jan 14.


Chromatin at the intersection of viral infection and DNA damage.

Lilley CE, Chaurushiya MS, Weitzman MD.

Biochim Biophys Acta. 2010 Mar-Apr;1799(3-4):319-27. doi: 10.1016/j.bbagrm.2009.06.007. Epub 2009 Jul 17. Review.


Viral manipulation of DNA repair and cell cycle checkpoints.

Chaurushiya MS, Weitzman MD.

DNA Repair (Amst). 2009 Sep 2;8(9):1166-76. doi: 10.1016/j.dnarep.2009.04.016. Epub 2009 May 26. Review.

Supplemental Content

Loading ...
Support Center