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Gemcitabine Combination Nano Therapies for Pancreatic Cancer.

Samanta K, Setua S, Kumari S, Jaggi M, Yallapu MM, Chauhan SC.

Pharmaceutics. 2019 Nov 4;11(11). pii: E574. doi: 10.3390/pharmaceutics11110574. Review.


Ormeloxifene nanotherapy for cervical cancer treatment.

Chauhan N, Maher DM, Hafeez BB, Mandil H, Singh MM, Yallapu MM, Jaggi M, Chauhan SC.

Int J Nanomedicine. 2019 Sep 3;14:7107-7121. doi: 10.2147/IJN.S200944. eCollection 2019.


Cross-Linked Polyphenol-Based Drug Nano-Self-Assemblies Engineered to Blockade Prostate Cancer Senescence.

Nagesh PKB, Chowdhury P, Hatami E, Kumari S, Kashyap VK, Tripathi MK, Wagh S, Meibohm B, Chauhan SC, Jaggi M, Yallapu MM.

ACS Appl Mater Interfaces. 2019 Oct 23;11(42):38537-38554. doi: 10.1021/acsami.9b14738. Epub 2019 Oct 8.


A triphenylethylene nonsteroidal SERM attenuates cervical cancer growth.

Chauhan N, Maher DM, Yallapu MM, B Hafeez B, Singh MM, Chauhan SC, Jaggi M.

Sci Rep. 2019 Jul 29;9(1):10917. doi: 10.1038/s41598-019-46680-0.


Next-generation paclitaxel-nanoparticle formulation for pancreatic cancer treatment.

Massey AE, Sikander M, Chauhan N, Kumari S, Setua S, Shetty AB, Mandil H, Kashyap VK, Khan S, Jaggi M, Yallapu MM, Hafeez BB, Chauhan SC.

Nanomedicine. 2019 Aug;20:102027. doi: 10.1016/j.nano.2019.102027. Epub 2019 Jun 4.


Superparamagnetic iron oxide nanoparticles of curcumin enhance gemcitabine therapeutic response in pancreatic cancer.

Khan S, Setua S, Kumari S, Dan N, Massey A, Hafeez BB, Yallapu MM, Stiles ZE, Alabkaa A, Yue J, Ganju A, Behrman S, Jaggi M, Chauhan SC.

Biomaterials. 2019 Jul;208:83-97. doi: 10.1016/j.biomaterials.2019.04.005. Epub 2019 Apr 8.


Cucurbitacin D Reprograms Glucose Metabolic Network in Prostate Cancer.

Sikander M, Malik S, Chauhan N, Khan P, Kumari S, Kashyap VK, Khan S, Ganju A, Halaweish FT, Yallapu MM, Jaggi M, Chauhan SC.

Cancers (Basel). 2019 Mar 14;11(3). pii: E364. doi: 10.3390/cancers11030364.


Dietary fatty acids fine-tune Piezo1 mechanical response.

Romero LO, Massey AE, Mata-Daboin AD, Sierra-Valdez FJ, Chauhan SC, Cordero-Morales JF, Vásquez V.

Nat Commun. 2019 Mar 13;10(1):1200. doi: 10.1038/s41467-019-09055-7.


Mannose-decorated hybrid nanoparticles for enhanced macrophage targeting.

Hatami E, Mu Y, Shields DN, Chauhan SC, Kumar S, Cory TJ, Yallapu MM.

Biochem Biophys Rep. 2019 Jan 25;17:197-207. doi: 10.1016/j.bbrep.2019.01.007. eCollection 2019 Mar.


Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer.

Kashyap VK, Wang Q, Setua S, Nagesh PKB, Chauhan N, Kumari S, Chowdhury P, Miller DD, Yallapu MM, Li W, Jaggi M, Hafeez BB, Chauhan SC.

J Exp Clin Cancer Res. 2019 Jan 23;38(1):29. doi: 10.1186/s13046-018-1009-7.


Tannic acid-inspired paclitaxel nanoparticles for enhanced anticancer effects in breast cancer cells.

Chowdhury P, Nagesh PKB, Hatami E, Wagh S, Dan N, Tripathi MK, Khan S, Hafeez BB, Meibohm B, Chauhan SC, Jaggi M, Yallapu MM.

J Colloid Interface Sci. 2019 Feb 1;535:133-148. doi: 10.1016/j.jcis.2018.09.072. Epub 2018 Sep 22.


Z Probe, An Efficient Tool for Characterizing Long Non-Coding RNA in FFPE Tissues.

Tripathi MK, Zacheaus C, Doxtater K, Keramatnia F, Gao C, Yallapu MM, Jaggi M, Chauhan SC.

Noncoding RNA. 2018 Sep 5;4(3). pii: E20. doi: 10.3390/ncrna4030020.


miRNA-205 Nanoformulation Sensitizes Prostate Cancer Cells to Chemotherapy.

Nagesh PKB, Chowdhury P, Hatami E, Boya VKN, Kashyap VK, Khan S, Hafeez BB, Chauhan SC, Jaggi M, Yallapu MM.

Cancers (Basel). 2018 Aug 25;10(9). pii: E289. doi: 10.3390/cancers10090289.


Transmembrane mucin MUC13 distinguishes intraductal papillary mucinous neoplasms from non-mucinous cysts and is associated with high-risk lesions.

Stiles ZE, Khan S, Patton KT, Jaggi M, Behrman SW, Chauhan SC.

HPB (Oxford). 2019 Jan;21(1):87-95. doi: 10.1016/j.hpb.2018.07.009. Epub 2018 Aug 14.


Development of polyvinylpyrrolidone/paclitaxel self-assemblies for breast cancer.

Chowdhury P, Nagesh PKB, Khan S, Hafeez BB, Chauhan SC, Jaggi M, Yallapu MM.

Acta Pharm Sin B. 2018 Jul;8(4):602-614. doi: 10.1016/j.apsb.2017.10.004. Epub 2017 Dec 10.


Tannic Acid-Lung Fluid Assemblies Promote Interaction and Delivery of Drugs to Lung Cancer Cells.

Hatami E, Nagesh PKB, Chowdhury P, Chauhan SC, Jaggi M, Samarasinghe AE, Yallapu MM.

Pharmaceutics. 2018 Aug 1;10(3). pii: E111. doi: 10.3390/pharmaceutics10030111.


Optical study of chemotherapy efficiency in cancer treatment via intracellular structural disorder analysis using partial wave spectroscopy.

Almabadi HM, Nagesh PKB, Sahay P, Bhandari S, Eckstein EC, Jaggi M, Chauhan SC, Yallapu MM, Pradhan P.

J Biophotonics. 2018 Dec;11(12):e201800056. doi: 10.1002/jbio.201800056. Epub 2018 Sep 26.


Role of lncRNAs in ovarian cancer: defining new biomarkers for therapeutic purposes.

Tripathi MK, Doxtater K, Keramatnia F, Zacheaus C, Yallapu MM, Jaggi M, Chauhan SC.

Drug Discov Today. 2018 Sep;23(9):1635-1643. doi: 10.1016/j.drudis.2018.04.010. Epub 2018 Apr 23. Review.


Antibody-Drug Conjugates for Cancer Therapy: Chemistry to Clinical Implications.

Dan N, Setua S, Kashyap VK, Khan S, Jaggi M, Yallapu MM, Chauhan SC.

Pharmaceuticals (Basel). 2018 Apr 9;11(2). pii: E32. doi: 10.3390/ph11020032. Review.


Tannic Acid Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Prostate Cancer.

Nagesh PKB, Hatami E, Chowdhury P, Kashyap VK, Khan S, Hafeez BB, Chauhan SC, Jaggi M, Yallapu MM.

Cancers (Basel). 2018 Mar 7;10(3). pii: E68. doi: 10.3390/cancers10030068.


Targeting IκappaB kinases for cancer therapy.

Awasthee N, Rai V, Chava S, Nallasamy P, Kunnumakkara AB, Bishayee A, Chauhan SC, Challagundla KB, Gupta SC.

Semin Cancer Biol. 2019 Jun;56:12-24. doi: 10.1016/j.semcancer.2018.02.007. Epub 2018 Feb 24. Review.


MUC13 contributes to rewiring of glucose metabolism in pancreatic cancer.

Kumari S, Khan S, Gupta SC, Kashyap VK, Yallapu MM, Chauhan SC, Jaggi M.

Oncogenesis. 2018 Feb 22;7(2):19. doi: 10.1038/s41389-018-0031-0.


Protein kinase D1 regulates subcellular localisation and metastatic function of metastasis-associated protein 1.

Ganju A, Chauhan SC, Hafeez BB, Doxtater K, Tripathi MK, Zafar N, Yallapu MM, Kumar R, Jaggi M.

Br J Cancer. 2018 Feb 20;118(4):587-599. doi: 10.1038/bjc.2017.431. Epub 2018 Feb 20.


Clinical significance of MUC13 in pancreatic ductal adenocarcinoma.

Khan S, Zafar N, Khan SS, Setua S, Behrman SW, Stiles ZE, Yallapu MM, Sahay P, Ghimire H, Ise T, Nagata S, Wang L, Wan JY, Pradhan P, Jaggi M, Chauhan SC.

HPB (Oxford). 2018 Jun;20(6):563-572. doi: 10.1016/j.hpb.2017.12.003. Epub 2018 Jan 17.


Quantification of photonic localization properties of targeted nuclear mass density variations: Application in cancer-stage detection.

Sahay P, Ganju A, Almabadi HM, Ghimire HM, Yallapu MM, Skalli O, Jaggi M, Chauhan SC, Pradhan P.

J Biophotonics. 2018 May;11(5):e201700257. doi: 10.1002/jbio.201700257. Epub 2018 Jan 17.


miR-145: Revival of a Dragon in Pancreatic Cancer.

Setua S, Khan S, Doxtater K, Yallapu MM, Jaggi M, Chauhan SC.

J Nat Sci. 2017 Mar;3(3). pii: e332.


Ormeloxifene Suppresses Prostate Tumor Growth and Metastatic Phenotypes via Inhibition of Oncogenic β-catenin Signaling and EMT Progression.

Hafeez BB, Ganju A, Sikander M, Kashyap VK, Hafeez ZB, Chauhan N, Malik S, Massey AE, Tripathi MK, Halaweish FT, Zafar N, Singh MM, Yallapu MM, Chauhan SC, Jaggi M.

Mol Cancer Ther. 2017 Oct;16(10):2267-2280. doi: 10.1158/1535-7163.MCT-17-0157. Epub 2017 Jun 14.


Magnetic nanoformulations for prostate cancer.

Chowdhury P, Roberts AM, Khan S, Hafeez BB, Chauhan SC, Jaggi M, Yallapu MM.

Drug Discov Today. 2017 Aug;22(8):1233-1241. doi: 10.1016/j.drudis.2017.04.018. Epub 2017 May 16. Review.


Disparity in rates of HPV infection and cervical cancer in underserved US populations.

Karuri AR, Kashyap VK, Yallapu MM, Zafar N, Kedia SK, Jaggi M, Chauhan SC.

Front Biosci (Schol Ed). 2017 Jun 1;9:254-269. Review.


Probing mucin interaction behavior of magnetic nanoparticles.

Boya VN, Lovett R, Setua S, Gandhi V, Nagesh PKB, Khan S, Jaggi M, Yallapu MM, Chauhan SC.

J Colloid Interface Sci. 2017 Feb 15;488:258-268. doi: 10.1016/j.jcis.2016.10.090. Epub 2016 Nov 1.


Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer.

Sikander M, Hafeez BB, Malik S, Alsayari A, Halaweish FT, Yallapu MM, Chauhan SC, Jaggi M.

Sci Rep. 2016 Nov 8;6:36594. doi: 10.1038/srep36594.


miRNA nanotherapeutics for cancer.

Ganju A, Khan S, Hafeez BB, Behrman SW, Yallapu MM, Chauhan SC, Jaggi M.

Drug Discov Today. 2017 Feb;22(2):424-432. doi: 10.1016/j.drudis.2016.10.014. Epub 2016 Nov 1. Review.


Restitution of Tumor Suppressor MicroRNA-145 Using Magnetic Nanoformulation for Pancreatic Cancer Therapy.

Setua S, Khan S, Yallapu MM, Behrman SW, Sikander M, Khan SS, Jaggi M, Chauhan SC.

J Gastrointest Surg. 2017 Jan;21(1):94-105. doi: 10.1007/s11605-016-3222-z. Epub 2016 Aug 9.


MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression.

Khan S, Sikander M, Ebeling MC, Ganju A, Kumari S, Yallapu MM, Hafeez BB, Ise T, Nagata S, Zafar N, Behrman SW, Wan JY, Ghimire HM, Sahay P, Pradhan P, Chauhan SC, Jaggi M.

Oncogene. 2017 Jan 26;36(4):491-500. doi: 10.1038/onc.2016.218. Epub 2016 Jun 20.


PSMA targeted docetaxel-loaded superparamagnetic iron oxide nanoparticles for prostate cancer.

Nagesh PKB, Johnson NR, Boya VKN, Chowdhury P, Othman SF, Khalilzad-Sharghi V, Hafeez BB, Ganju A, Khan S, Behrman SW, Zafar N, Chauhan SC, Jaggi M, Yallapu MM.

Colloids Surf B Biointerfaces. 2016 Aug 1;144:8-20. doi: 10.1016/j.colsurfb.2016.03.071. Epub 2016 Mar 26.


Curcumin Nanoformulation for Cervical Cancer Treatment.

Zaman MS, Chauhan N, Yallapu MM, Gara RK, Maher DM, Kumari S, Sikander M, Khan S, Zafar N, Jaggi M, Chauhan SC.

Sci Rep. 2016 Feb 3;6:20051. doi: 10.1038/srep20051.


Revisiting stroma in pancreatic cancer.

Khan S, Jaggi M, Chauhan SC.

Oncoscience. 2015 Aug 21;2(10):819-20. eCollection 2015. No abstract available.


Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy.

Sane S, Abdullah A, Nelson ME, Wang H, Chauhan SC, Newton SS, Rezvani K.

Cell Stress Chaperones. 2016 Mar;21(2):313-26. doi: 10.1007/s12192-015-0661-5. Epub 2015 Dec 4.


Therapeutic Applications of Curcumin Nanoformulations.

Yallapu MM, Nagesh PK, Jaggi M, Chauhan SC.

AAPS J. 2015 Nov;17(6):1341-56. doi: 10.1208/s12248-015-9811-z. Epub 2015 Sep 3. Review.


Approach for chemosensitization of cisplatin-resistant ovarian cancer by cucurbitacin B.

El-Senduny FF, Badria FA, El-Waseef AM, Chauhan SC, Halaweish F.

Tumour Biol. 2016 Jan;37(1):685-98. doi: 10.1007/s13277-015-3773-8. Epub 2015 Aug 5.


Nanoparticle formulation of ormeloxifene for pancreatic cancer.

Khan S, Chauhan N, Yallapu MM, Ebeling MC, Balakrishna S, Ellis RT, Thompson PA, Balabathula P, Behrman SW, Zafar N, Singh MM, Halaweish FT, Jaggi M, Chauhan SC.

Biomaterials. 2015;53:731-43. doi: 10.1016/j.biomaterials.2015.02.082. Epub 2015 Mar 26.


Ormeloxifene suppresses desmoplasia and enhances sensitivity of gemcitabine in pancreatic cancer.

Khan S, Ebeling MC, Chauhan N, Thompson PA, Gara RK, Ganju A, Yallapu MM, Behrman SW, Zhao H, Zafar N, Singh MM, Jaggi M, Chauhan SC.

Cancer Res. 2015 Jun 1;75(11):2292-304. doi: 10.1158/0008-5472.CAN-14-2397. Epub 2015 Apr 3. Erratum in: Cancer Res. 2018 May 1;78(9):2444.


Implications of protein corona on physico-chemical and biological properties of magnetic nanoparticles.

Yallapu MM, Chauhan N, Othman SF, Khalilzad-Sharghi V, Ebeling MC, Khan S, Jaggi M, Chauhan SC.

Biomaterials. 2015 Apr;46:1-12. doi: 10.1016/j.biomaterials.2014.12.045. Epub 2015 Jan 15.


Ormeloxifene efficiently inhibits ovarian cancer growth.

Maher DM, Khan S, Nordquist JL, Ebeling MC, Bauer NA, Kopel L, Singh MM, Halaweish F, Bell MC, Jaggi M, Chauhan SC.

Cancer Lett. 2015 Jan 28;356(2 Pt B):606-12. doi: 10.1016/j.canlet.2014.10.009. Epub 2014 Oct 13.


MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer.

Khan S, Ebeling MC, Zaman MS, Sikander M, Yallapu MM, Chauhan N, Yacoubian AM, Behrman SW, Zafar N, Kumar D, Thompson PA, Jaggi M, Chauhan SC.

Oncotarget. 2014 Sep 15;5(17):7599-609.


Slit/Robo pathway: a promising therapeutic target for cancer.

Gara RK, Kumari S, Ganju A, Yallapu MM, Jaggi M, Chauhan SC.

Drug Discov Today. 2015 Jan;20(1):156-64. doi: 10.1016/j.drudis.2014.09.008. Epub 2014 Sep 20. Review.


Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating β-catenin/T cell factor activity.

Sundram V, Ganju A, Hughes JE, Khan S, Chauhan SC, Jaggi M.

Oncotarget. 2014 Aug 30;5(16):6867-84.


The roles of cellular nanomechanics in cancer.

Yallapu MM, Katti KS, Katti DR, Mishra SR, Khan S, Jaggi M, Chauhan SC.

Med Res Rev. 2015 Jan;35(1):198-223. doi: 10.1002/med.21329. Epub 2014 Aug 18. Review.


Anti-cancer activity of curcumin loaded nanoparticles in prostate cancer.

Yallapu MM, Khan S, Maher DM, Ebeling MC, Sundram V, Chauhan N, Ganju A, Balakrishna S, Gupta BK, Zafar N, Jaggi M, Chauhan SC.

Biomaterials. 2014 Oct;35(30):8635-48. doi: 10.1016/j.biomaterials.2014.06.040. Epub 2014 Jul 12.


Nanoways to overcome docetaxel resistance in prostate cancer.

Ganju A, Yallapu MM, Khan S, Behrman SW, Chauhan SC, Jaggi M.

Drug Resist Updat. 2014 Apr;17(1-2):13-23. doi: 10.1016/j.drup.2014.04.001. Epub 2014 Apr 5. Review.

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