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Feasibility of Using Crystal Geometry for a DOI Scintillation Detector.

Valenciaga Y, Prout DL, Taschereau R, Chatziioannou AF.

IEEE Trans Radiat Plasma Med Sci. 2018 May;2(3):161-169. doi: 10.1109/TRPMS.2018.2760857. Epub 2017 Oct 6.


Performance Evaluation of G8, a High-Sensitivity Benchtop Preclinical PET/CT Tomograph.

Gu Z, Taschereau R, Vu NT, Prout DL, Silverman RW, Lee JT, Chatziioannou AF.

J Nucl Med. 2019 Jan;60(1):142-149. doi: 10.2967/jnumed.118.208827. Epub 2018 Jun 14.


Immuno-PET in Inflammatory Bowel Disease: Imaging CD4-Positive T Cells in a Murine Model of Colitis.

Freise AC, Zettlitz KA, Salazar FB, Tavaré R, Tsai WK, Chatziioannou AF, Rozengurt N, Braun J, Wu AM.

J Nucl Med. 2018 Jun;59(6):980-985. doi: 10.2967/jnumed.117.199075. Epub 2018 Jan 11.


ARAS: an automated radioactivity aliquoting system for dispensing solutions containing positron-emitting radioisotopes.

Dooraghi AA, Carroll L, Collins J, van Dam RM, Chatziioannou AF.

EJNMMI Res. 2016 Dec;6(1):22. doi: 10.1186/s13550-016-0176-9. Epub 2016 Mar 9.


Quantitative assessments of glycolysis from single cells.

Shin YS, Kim J, Johnson D, Dooraghi AA, Mai WX, Ta L, Chatziioannou AF, Phelps ME, Nathanson DA, Heath JR.

Technology (Singap World Sci). 2015 Jun;3(4):172-178. Epub 2015 Jun 25.


A DOI Detector With Crystal Scatter Identification Capability for High Sensitivity and High Spatial Resolution PET Imaging.

Gu Z, Prout DL, Silverman RW, Herman H, Dooraghi A, Chatziioannou AF.

IEEE Trans Nucl Sci. 2015 Jun;62(3):740-747.


Optimization of the Energy Window for PETbox4, a Preclinical PET Tomograph With a Small Inner Diameter.

Gu Z, Bao Q, Taschereau R, Wang H, Bai B, Chatziioannou AF.

IEEE Trans Nucl Sci. 2014 Jun 1;61(3):1164-1173.


A deformable atlas of the laboratory mouse.

Wang H, Stout DB, Chatziioannou AF.

Mol Imaging Biol. 2015 Feb;17(1):18-28. doi: 10.1007/s11307-014-0767-7.


Fast metabolic response to drug intervention through analysis on a miniaturized, highly integrated molecular imaging system.

Wang J, Hwang K, Braas D, Dooraghi A, Nathanson D, Campbell DO, Gu Y, Sandberg T, Mischel P, Radu C, Chatziioannou AF, Phelps ME, Christofk H, Heath JR.

J Nucl Med. 2013 Oct;54(10):1820-4. doi: 10.2967/jnumed.112.118497. Epub 2013 Aug 26.


Optimization of microfluidic PET tracer synthesis with Cerenkov imaging.

Dooraghi AA, Keng PY, Chen S, Javed MR, Kim CJ, Chatziioannou AF, van Dam RM.

Analyst. 2013 Oct 7;138(19):5654-64. doi: 10.1039/c3an01113e.


NEMA NU-4 performance evaluation of PETbox4, a high sensitivity dedicated PET preclinical tomograph.

Gu Z, Taschereau R, Vu NT, Wang H, Prout DL, Silverman RW, Bai B, Stout DB, Phelps ME, Chatziioannou AF.

Phys Med Biol. 2013 Jun 7;58(11):3791-814. doi: 10.1088/0031-9155/58/11/3791. Epub 2013 May 10.


Betabox: a beta particle imaging system based on a position sensitive avalanche photodiode.

Dooraghi AA, Vu NT, Silverman RW, Farrell R, Shah KS, Wang J, Heath JR, Chatziioannou AF.

Phys Med Biol. 2013 Jun 7;58(11):3739-53. doi: 10.1088/0031-9155/58/11/3739. Epub 2013 May 8.


A method of 2D/3D registration of a statistical mouse atlas with a planar X-ray projection and an optical photo.

Wang H, Stout DB, Chatziioannou AF.

Med Image Anal. 2013 May;17(4):401-16. doi: 10.1016/ Epub 2013 Mar 5.


MARS: a mouse atlas registration system based on a planar x-ray projector and an optical camera.

Wang H, Stout DB, Taschereau R, Gu Z, Vu NT, Prout DL, Chatziioannou AF.

Phys Med Biol. 2012 Oct 7;57(19):6063-77. doi: 10.1088/0031-9155/57/19/6063. Epub 2012 Sep 12.


NEMA NU 4-2008 comparison of preclinical PET imaging systems.

Goertzen AL, Bao Q, Bergeron M, Blankemeyer E, Blinder S, Cañadas M, Chatziioannou AF, Dinelle K, Elhami E, Jans HS, Lage E, Lecomte R, Sossi V, Surti S, Tai YC, Vaquero JJ, Vicente E, Williams DA, Laforest R.

J Nucl Med. 2012 Aug;53(8):1300-9. doi: 10.2967/jnumed.111.099382. Epub 2012 Jun 14.


Micro-chemical synthesis of molecular probes on an electronic microfluidic device.

Keng PY, Chen S, Ding H, Sadeghi S, Shah GJ, Dooraghi A, Phelps ME, Satyamurthy N, Chatziioannou AF, Kim CJ, van Dam RM.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):690-5. doi: 10.1073/pnas.1117566109. Epub 2011 Dec 30.


Mouse atlas registration with non-tomographic imaging modalities-a pilot study based on simulation.

Wang H, Stout DB, Chatziioannou AF.

Mol Imaging Biol. 2012 Aug;14(4):408-19. doi: 10.1007/s11307-011-0519-x.


Estimation of mouse organ locations through registration of a statistical mouse atlas with micro-CT images.

Wang H, Stout DB, Chatziioannou AF.

IEEE Trans Med Imaging. 2012 Jan;31(1):88-102. doi: 10.1109/TMI.2011.2165294. Epub 2011 Aug 18.


A beta-camera integrated with a microfluidic chip for radioassays based on real-time imaging of glycolysis in small cell populations.

Vu NT, Yu ZT, Comin-Anduix B, Søndergaard JN, Silverman RW, Chang CY, Ribas A, Tseng HR, Chatziioannou AF.

J Nucl Med. 2011 May;52(5):815-21. doi: 10.2967/jnumed.110.078725.


Performance Characteristics of BGO Detectors for a Low Cost Preclinical PET Scanner.

Zhang H, Vu NT, Bao Q, Silverman RW, Berry-Pusey BN, Douraghy A, Williams DA, Rannou FR, Stout DB, Chatziioannou AF.

IEEE Trans Nucl Sci. 2010 Jun 1;57(3):1038-1044.


Combined inhibition of the BMP pathway and the RANK-RANKL axis in a mixed lytic/blastic prostate cancer lesion.

Virk MS, Alaee F, Petrigliano FA, Sugiyama O, Chatziioannou AF, Stout D, Dougall WC, Lieberman JR.

Bone. 2011 Mar 1;48(3):578-87. doi: 10.1016/j.bone.2010.11.003. Epub 2010 Nov 10.


Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples.

Fang C, Wang Y, Vu NT, Lin WY, Hsieh YT, Rubbi L, Phelps ME, Müschen M, Kim YM, Chatziioannou AF, Tseng HR, Graeber TG.

Cancer Res. 2010 Nov 1;70(21):8299-308. doi: 10.1158/0008-5472.CAN-10-0851. Epub 2010 Sep 13.


Performance evaluation of PETbox: a low cost bench top preclinical PET scanner.

Zhang H, Bao Q, Vu NT, Silverman RW, Taschereau R, Berry-Pusey BN, Douraghy A, Rannou FR, Stout DB, Chatziioannou AF.

Mol Imaging Biol. 2011 Oct;13(5):949-61. doi: 10.1007/s11307-010-0413-y.


In vivo mouse bioluminescence tomography with radionuclide-based imaging validation.

Lu Y, Machado HB, Bao Q, Stout D, Herschman H, Chatziioannou AF.

Mol Imaging Biol. 2011 Feb;13(1):53-8. doi: 10.1007/s11307-010-0332-y.


Dual-energy attenuation coefficient decomposition with differential filtration and application to a microCT scanner.

Taschereau R, Silverman RW, Chatziioannou AF.

Phys Med Biol. 2010 Feb 21;55(4):1141-55. doi: 10.1088/0031-9155/55/4/016. Epub 2010 Jan 28.


Cerenkov radiation imaging as a method for quantitative measurements of beta particles in a microfluidic chip.

Cho JS, Taschereau R, Olma S, Liu K, Chen YC, Shen CK, van Dam RM, Chatziioannou AF.

Phys Med Biol. 2009 Nov 21;54(22):6757-71. doi: 10.1088/0031-9155/54/22/001. Epub 2009 Oct 21.


Spectrally resolved bioluminescence tomography with the third-order simplified spherical harmonics approximation.

Lu Y, Douraghy A, Machado HB, Stout D, Tian J, Herschman H, Chatziioannou AF.

Phys Med Biol. 2009 Nov 7;54(21):6477-93. doi: 10.1088/0031-9155/54/21/003. Epub 2009 Oct 9.


Experimental bioluminescence tomography with fully parallel radiative-transfer-based reconstruction framework.

Lu Y, Machado HB, Douraghy A, Stout D, Herschman H, Chatziioannou AF.

Opt Express. 2009 Sep 14;17(19):16681-95. doi: 10.1364/OE.17.016681.


Source reconstruction for spectrally-resolved bioluminescence tomography with sparse a priori information.

Lu Y, Zhang X, Douraghy A, Stout D, Tian J, Chan TF, Chatziioannou AF.

Opt Express. 2009 May 11;17(10):8062-80.


Performance evaluation of the inveon dedicated PET preclinical tomograph based on the NEMA NU-4 standards.

Bao Q, Newport D, Chen M, Stout DB, Chatziioannou AF.

J Nucl Med. 2009 Mar;50(3):401-8. doi: 10.2967/jnumed.108.056374. Epub 2009 Feb 17.


A facile route to bulk high-Z polymer composites for gamma ray scintillation.

Zhao YS, Yu Z, Douraghy A, Chatziioannou AF, Mo Y, Pei Q.

Chem Commun (Camb). 2008 Dec 7;(45):6008-10. doi: 10.1039/b813571a. Epub 2008 Oct 14.


Influence of simultaneous targeting of the bone morphogenetic protein pathway and RANK/RANKL axis in osteolytic prostate cancer lesion in bone.

Virk MS, Petrigliano FA, Liu NQ, Chatziioannou AF, Stout D, Kang CO, Dougall WC, Lieberman JR.

Bone. 2009 Jan;44(1):160-7. doi: 10.1016/j.bone.2008.09.009. Epub 2008 Sep 26.


FPGA Electronics for OPET: A Dual-Modality Optical and Positron Emission Tomograph.

Douraghy A, Rannou FR, Silverman RW, Chatziioannou AF.

IEEE Trans Nucl Sci. 2008 Oct 1;55(5):2541-2545.


Adenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer.

Burton JB, Johnson M, Sato M, Koh SB, Mulholland DJ, Stout D, Chatziioannou AF, Phelps ME, Wu H, Wu L.

Nat Med. 2008 Aug;14(8):882-8. doi: 10.1038/nm.1727. Epub 2008 Jul 11.


Characterization of osteolytic, osteoblastic, and mixed lesions in a prostate cancer mouse model using 18F-FDG and 18F-fluoride PET/CT.

Hsu WK, Virk MS, Feeley BT, Stout DB, Chatziioannou AF, Lieberman JR.

J Nucl Med. 2008 Mar;49(3):414-21. doi: 10.2967/jnumed.107.045666. Epub 2008 Feb 20.


Compressed voxels for high-resolution phantom simulations in GATE.

Taschereau R, Chatziioannou AF.

Mol Imaging Biol. 2008 Jan-Feb;10(1):40-7.


Monte Carlo simulations of absorbed dose in a mouse phantom from 18-fluorine compounds.

Taschereau R, Chatziioannou AF.

Med Phys. 2007 Mar;34(3):1026-36.


The use of 18F-fluoride and 18F-FDG PET scans to assess fracture healing in a rat femur model.

Hsu WK, Feeley BT, Krenek L, Stout DB, Chatziioannou AF, Lieberman JR.

Eur J Nucl Med Mol Imaging. 2007 Aug;34(8):1291-301. Epub 2007 Mar 3.


Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT, and bioluminescence imaging.

Deroose CM, De A, Loening AM, Chow PL, Ray P, Chatziioannou AF, Gambhir SS.

J Nucl Med. 2007 Feb;48(2):295-303.


Digimouse: a 3D whole body mouse atlas from CT and cryosection data.

Dogdas B, Stout D, Chatziioannou AF, Leahy RM.

Phys Med Biol. 2007 Feb 7;52(3):577-87. Epub 2007 Jan 10.


Noninvasive measurement of cardiovascular function in mice with high-temporal-resolution small-animal PET.

Kreissl MC, Wu HM, Stout DB, Ladno W, Schindler TH, Zhang X, Prior JO, Prins ML, Chatziioannou AF, Huang SC, Schelbert HR.

J Nucl Med. 2006 Jun;47(6):974-80.


Effect of optical property estimation accuracy on tomographic bioluminescence imaging: simulation of a combined optical-PET (OPET) system.

Alexandrakis G, Rannou FR, Chatziioannou AF.

Phys Med Biol. 2006 Apr 21;51(8):2045-53. Epub 2006 Apr 3.


Monte carlo simulations of dose from microCT imaging procedures in a realistic mouse phantom.

Taschereau R, Chow PL, Chatziioannou AF.

Med Phys. 2006 Jan;33(1):216-24.


Investigation of OPET Performance Using GATE, a Geant4-Based Simulation Software.

Rannou FR, Kohli V, Prout DL, Chatziioannou AF.

IEEE Trans Nucl Sci. 2004 Oct;51(5):2713-2717.


A method of image registration for small animal, multi-modality imaging.

Chow PL, Stout DB, Komisopoulou E, Chatziioannou AF.

Phys Med Biol. 2006 Jan 21;51(2):379-90. Epub 2006 Jan 4.


Instrumentation for molecular imaging in preclinical research: Micro-PET and Micro-SPECT.

Chatziioannou AF.

Proc Am Thorac Soc. 2005;2(6):533-6, 510-11. Review.


Small animal imaging center design: the facility at the UCLA Crump Institute for Molecular Imaging.

Stout DB, Chatziioannou AF, Lawson TP, Silverman RW, Gambhir SS, Phelps ME.

Mol Imaging Biol. 2005 Nov-Dec;7(6):393-402.

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