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Items: 10

1.

Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease.

Perni RB, Almquist SJ, Byrn RA, Chandorkar G, Chaturvedi PR, Courtney LF, Decker CJ, Dinehart K, Gates CA, Harbeson SL, Heiser A, Kalkeri G, Kolaczkowski E, Lin K, Luong YP, Rao BG, Taylor WP, Thomson JA, Tung RD, Wei Y, Kwong AD, Lin C.

Antimicrob Agents Chemother. 2006 Mar;50(3):899-909.

2.

Prediction of pharmacokinetic properties using experimental approaches during early drug discovery.

Chaturvedi PR, Decker CJ, Odinecs A.

Curr Opin Chem Biol. 2001 Aug;5(4):452-63. Review.

PMID:
11470610
3.

The novel IMPDH inhibitor VX-497 prolongs skin graft survival and improves graft versus host disease in mice.

Decker CJ, Heiser AD, Chaturvedi PR, Faust TJ, Ku G, Moseley S, Nimmesgern E.

Drugs Exp Clin Res. 2001;27(3):89-95.

PMID:
11447770
4.

Phase I and pharmacokinetic study of the novel MDR1 and MRP1 inhibitor biricodar administered alone and in combination with doxorubicin.

Peck RA, Hewett J, Harding MW, Wang YM, Chaturvedi PR, Bhatnagar A, Ziessman H, Atkins F, Hawkins MJ.

J Clin Oncol. 2001 Jun 15;19(12):3130-41.

PMID:
11408511
5.

Metabolism of amprenavir in liver microsomes: role of CYP3A4 inhibition for drug interactions.

Decker CJ, Laitinen LM, Bridson GW, Raybuck SA, Tung RD, Chaturvedi PR.

J Pharm Sci. 1998 Jul;87(7):803-7.

PMID:
9649346
6.

Pharmacokinetics and safety of single oral doses of VX-366 (isobutyramide) in healthy volunteers.

Brettman LR, Chaturvedi PR.

J Clin Pharmacol. 1996 Jul;36(7):617-22.

PMID:
8844444
7.

Stability studies of gabapentin in aqueous solutions.

Zour E, Lodhi SA, Nesbitt RU, Silbering SB, Chaturvedi PR.

Pharm Res. 1992 May;9(5):595-600.

PMID:
1608888
8.

Effect of terminal heat sterilization on the stability of phospholipid-stabilized submicron emulsions.

Chaturvedi PR, Patel NM, Lodhi SA.

Acta Pharm Nord. 1992;4(1):51-5.

PMID:
1515053
9.

The influence of diffusional barriers on presystemic gut elimination.

Gwilt PR, Comer S, Chaturvedi PR, Waters DH.

Drug Metab Dispos. 1988 Jul-Aug;16(4):521-6.

PMID:
2903017
10.

Steady state absorption kinetics and pharmacodynamics of furosemide in congestive heart failure.

Chaturvedi PR, O'Donnell JP, Nicholas JM, Shoenthal DR, Waters DH, Gwilt PR.

Int J Clin Pharmacol Ther Toxicol. 1987 Mar;25(3):123-8.

PMID:
3557737

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