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Items: 46

1.

Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers.

Lyu X, Chastain M, Chai W.

BMC Genomics. 2019 Jul 12;20(1):579. doi: 10.1186/s12864-019-5934-4.

2.

The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells.

Huang C, Jia P, Chastain M, Shiva O, Chai W.

Exp Cell Res. 2017 Jun 15;355(2):95-104. doi: 10.1016/j.yexcr.2017.03.058. Epub 2017 Mar 31.

3.

Human MLH1 suppresses the insertion of telomeric sequences at intra-chromosomal sites in telomerase-expressing cells.

Jia P, Chastain M, Zou Y, Her C, Chai W.

Nucleic Acids Res. 2017 Feb 17;45(3):1219-1232. doi: 10.1093/nar/gkw1170.

4.

Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress.

Chastain M, Zhou Q, Shiva O, Fadri-Moskwik M, Whitmore L, Jia P, Dai X, Huang C, Ye P, Chai W.

Cell Rep. 2016 Aug 16;16(7):2048. doi: 10.1016/j.celrep.2016.08.008. No abstract available.

5.

Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress.

Chastain M, Zhou Q, Shiva O, Fadri-Moskwik M, Whitmore L, Jia P, Dai X, Huang C, Ye P, Chai W.

Cell Rep. 2016 Aug 2;16(5):1300-1314. doi: 10.1016/j.celrep.2016.06.077. Erratum in: Cell Rep. 2016 Aug 16;16(7):2048.

6.

Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma.

Puzanov I, Milhem MM, Minor D, Hamid O, Li A, Chen L, Chastain M, Gorski KS, Anderson A, Chou J, Kaufman HL, Andtbacka RH.

J Clin Oncol. 2016 Aug 1;34(22):2619-26. doi: 10.1200/JCO.2016.67.1529. Epub 2016 Jun 13.

PMID:
27298410
7.

Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies.

Li Y, Burns JA, Cheney CA, Zhang N, Vitelli S, Wang F, Bett A, Chastain M, Audoly LP, Zhang ZQ.

Biologics. 2010 Jun 24;4:163-71.

8.

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.

Loboda A, Nebozhyn M, Klinghoffer R, Frazier J, Chastain M, Arthur W, Roberts B, Zhang T, Chenard M, Haines B, Andersen J, Nagashima K, Paweletz C, Lynch B, Feldman I, Dai H, Huang P, Watters J.

BMC Med Genomics. 2010 Jun 30;3:26. doi: 10.1186/1755-8794-3-26.

9.

Angiotropic neonatal congenital melanocytic nevus: how extravascular migration of melanocytes may explain the development of congenital nevi.

Barnhill RL, Chastain MA, Jerdan MS, Lebbé C, Janin A, Lugassy C.

Am J Dermatopathol. 2010 Jul;32(5):495-9. doi: 10.1097/DAD.0b013e3181c6afce.

PMID:
20442637
10.

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.

Aste-Amézaga M, Zhang N, Lineberger JE, Arnold BA, Toner TJ, Gu M, Huang L, Vitelli S, Vo KT, Haytko P, Zhao JZ, Baleydier F, L'Heureux S, Wang H, Gordon WR, Thoryk E, Andrawes MB, Tiyanont K, Stegmaier K, Roti G, Ross KN, Franlin LL, Wang H, Wang F, Chastain M, Bett AJ, Audoly LP, Aster JC, Blacklow SC, Huber HE.

PLoS One. 2010 Feb 8;5(2):e9094. doi: 10.1371/journal.pone.0009094.

11.

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions.

Joyce JG, Krauss IJ, Song HC, Opalka DW, Grimm KM, Nahas DD, Esser MT, Hrin R, Feng M, Dudkin VY, Chastain M, Shiver JW, Danishefsky SJ.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15684-9. doi: 10.1073/pnas.0807837105. Epub 2008 Oct 6.

12.

Enhanced in vivo transgene expression and immunogenicity from plasmid vectors following electrostimulation in rodents and primates.

Simon AJ, Casimiro DR, Finnefrock AC, Davies ME, Tang A, Chen M, Chastain M, Kath GS, Chen L, Shiver JW.

Vaccine. 2008 Sep 19;26(40):5202-9. doi: 10.1016/j.vaccine.2008.03.058. Epub 2008 Apr 14.

PMID:
18472195
13.

Investigation of the terminal P4 domain in a series of D-phenylglycinamide-based factor Xa inhibitors.

Franciskovich JB, Masters JJ, Weber WW, Klimkowski VJ, Chouinard M, Sipes PR, Johnson LM, Snyder DW, Chastain MK, Craft TJ, Towner RD, Gifford-Moore DS, Froelich LL, Smallwood JK, Foster RS, Smith GF, Liebeschuetz JW, Murray CW, Young SC.

Bioorg Med Chem Lett. 2007 Dec 15;17(24):6910-3. Epub 2007 Oct 24.

PMID:
17976987
14.

D-phenylglycinol-derived non-covalent factor Xa inhibitors: effect of non-peptidic S4 linkage elements on affinity and anticoagulant activity.

Klimkowski VJ, Watson BM, Wiley MR, Liebeschuetz J, Franciskovich JB, Marimuthu J, Bastian JA, Sall DJ, Smallwood JK, Chirgadze NY, Smith GF, Foster RS, Craft T, Sipes P, Chastain M, Sheehan SM.

Bioorg Med Chem Lett. 2007 Nov 1;17(21):5801-5. Epub 2007 Aug 28.

PMID:
17881231
15.

Fully synthetic carbohydrate HIV antigens designed on the logic of the 2G12 antibody.

Krauss IJ, Joyce JG, Finnefrock AC, Song HC, Dudkin VY, Geng X, Warren JD, Chastain M, Shiver JW, Danishefsky SJ.

J Am Chem Soc. 2007 Sep 12;129(36):11042-4. Epub 2007 Aug 21. No abstract available.

PMID:
17711286
16.

Improvement of cystic fibrosis during treatment with isotretinoin.

Buckley JL, Chastain MA, Rietschel RL.

Skinmed. 2006 Sep-Oct;5(5):252-5.

PMID:
16957442
17.
18.

Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor.

Bianchi E, Liang X, Ingallinella P, Finotto M, Chastain MA, Fan J, Fu TM, Song HC, Horton MS, Freed DC, Manger W, Wen E, Shi L, Ionescu R, Price C, Wenger M, Emini EA, Cortese R, Ciliberto G, Shiver JW, Pessi A.

J Virol. 2005 Jun;79(12):7380-8.

19.

Carbocyclic[g]indole inhibitors of human nonpancreatic s-PLA2.

Sawyer JS, Beight DW, Smith EC, Snyder DW, Chastain MK, Tielking RL, Hartley LW, Carlson DG.

J Med Chem. 2005 Feb 10;48(3):893-6.

PMID:
15689175
20.

Heterologous human immunodeficiency virus type 1 priming-boosting immunization strategies involving replication-defective adenovirus and poxvirus vaccine vectors.

Casimiro DR, Bett AJ, Fu TM, Davies ME, Tang A, Wilson KA, Chen M, Long R, McKelvey T, Chastain M, Gurunathan S, Tartaglia J, Emini EA, Shiver J.

J Virol. 2004 Oct;78(20):11434-8.

21.

Preclinical study of influenza virus A M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys.

Fan J, Liang X, Horton MS, Perry HC, Citron MP, Heidecker GJ, Fu TM, Joyce J, Przysiecki CT, Keller PM, Garsky VM, Ionescu R, Rippeon Y, Shi L, Chastain MA, Condra JH, Davies ME, Liao J, Emini EA, Shiver JW.

Vaccine. 2004 Aug 13;22(23-24):2993-3003.

PMID:
15297047
22.

T-cell response to adenovirus hexon and DNA-binding protein in mice.

McKelvey T, Tang A, Bett AJ, Casimiro DR, Chastain M.

Gene Ther. 2004 May;11(9):791-6.

PMID:
14961070
23.

Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene.

Casimiro DR, Chen L, Fu TM, Evans RK, Caulfield MJ, Davies ME, Tang A, Chen M, Huang L, Harris V, Freed DC, Wilson KA, Dubey S, Zhu DM, Nawrocki D, Mach H, Troutman R, Isopi L, Williams D, Hurni W, Xu Z, Smith JG, Wang S, Liu X, Guan L, Long R, Trigona W, Heidecker GJ, Perry HC, Persaud N, Toner TJ, Su Q, Liang X, Youil R, Chastain M, Bett AJ, Volkin DB, Emini EA, Shiver JW.

J Virol. 2003 Jun;77(11):6305-13.

24.

Mycobacterium chelonae/abscessus complex infection in a liver transplant patient.

Chastain MA, Buckley J, Russo GG.

Int J Dermatol. 2001 Dec;40(12):769-74. Review. No abstract available.

PMID:
11903675
25.

Vaccine-induced immune responses in rodents and nonhuman primates by use of a humanized human immunodeficiency virus type 1 pol gene.

Casimiro DR, Tang A, Perry HC, Long RS, Chen M, Heidecker GJ, Davies ME, Freed DC, Persaud NV, Dubey S, Smith JG, Havlir D, Richman D, Chastain MA, Simon AJ, Fu TM, Emini EA, Shiver JW.

J Virol. 2002 Jan;76(1):185-94.

26.

Chemical peels.

Monheit GD, Chastain MA.

Facial Plast Surg Clin North Am. 2001 May;9(2):239-55, viii. Review.

PMID:
11457690
27.

Deep dermatophytosis: report of 2 cases and review of the literature.

Chastain MA, Reed RJ, Pankey GA.

Cutis. 2001 Jun;67(6):457-62. Review.

PMID:
11419016
28.

The glucagonoma syndrome: a review of its features and discussion of new perspectives.

Chastain MA.

Am J Med Sci. 2001 May;321(5):306-20. Review.

PMID:
11370794
29.

HIV lipodystrophy: review of the syndrome and report of a case treated with liposuction.

Chastain MA, Chastain JB, Coleman WP.

Dermatol Surg. 2001 May;27(5):497-500.

PMID:
11359503
30.

Antigen levels and antibody titers after DNA vaccination.

Chastain M, Simon AJ, Soper KA, Holder DJ, Montgomery DL, Sagar SL, Casimiro DR, Middaugh CR.

J Pharm Sci. 2001 Apr;90(4):474-84.

PMID:
11170037
31.

Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination.

Barouch DH, Santra S, Schmitz JE, Kuroda MJ, Fu TM, Wagner W, Bilska M, Craiu A, Zheng XX, Krivulka GR, Beaudry K, Lifton MA, Nickerson CE, Trigona WL, Punt K, Freed DC, Guan L, Dubey S, Casimiro D, Simon A, Davies ME, Chastain M, Strom TB, Gelman RS, Montefiori DC, Lewis MG, Emini EA, Shiver JW, Letvin NL.

Science. 2000 Oct 20;290(5491):486-92.

32.

KID syndrome: report of a case and support for its reclassification as an ectodermal dysplasia.

Chastain MA, Russo GG, Boh EE.

Pediatr Dermatol. 2000 May-Jun;17(3):244-5. No abstract available.

PMID:
10886766
33.
34.

Pilomatrix dysplasia in an immunosuppressed patient.

Chastain MA, Millikan LE.

J Am Acad Dermatol. 2000 Jul;43(1 Pt 1):118-22.

PMID:
10863236
35.

More on the facelift flap.

Flynn TC, Chastain MA, McDonald WS.

Dermatol Surg. 2000 May;26(5):507-8. No abstract available.

PMID:
10847742
36.

The "facelift" flap for reconstruction of cheek, lateral orbit, and temple defects.

Flynn TC, McDonald WS, Chastain MA.

Dermatol Surg. 1999 Nov;25(11):836-43. Review.

PMID:
10594594
37.

Propylthiouracil hypersensitivity: report of two patients with vasculitis and review of the literature.

Chastain MA, Russo GG, Boh EE, Chastain JB, Falabella A, Millikan LE.

J Am Acad Dermatol. 1999 Nov;41(5 Pt 1):757-64. Review.

PMID:
10534640
38.

Enhancement of DNA vaccine potency using conventional aluminum adjuvants.

Ulmer JB, DeWitt CM, Chastain M, Friedman A, Donnelly JJ, McClements WL, Caulfield MJ, Bohannon KE, Volkin DB, Evans RK.

Vaccine. 1999 Aug 20;18(1-2):18-28.

PMID:
10501231
39.

Evaluation of activated protein C on canine infarct size in a nonthrombotic model of myocardial reperfusion injury.

Hahn RA, MacDonald BR, Chastain M, Grinnell BW, Simpson PJ.

J Pharmacol Exp Ther. 1996 Mar;276(3):1104-10.

PMID:
8786541
40.

Nucleoside triples from the group I intron.

Chastain M, Tinoco I Jr.

Biochemistry. 1993 Dec 28;32(51):14220-8.

PMID:
8260508
41.

A base-triple structural domain in RNA.

Chastain M, Tinoco I Jr.

Biochemistry. 1992 Dec 29;31(51):12733-41.

PMID:
1463745
42.

Poly(rA) binds poly(rG).poly(rC) to form a triple helix.

Chastain M, Tinoco I Jr.

Nucleic Acids Res. 1992 Jan 25;20(2):315-8.

43.

Synthesis and purification of large amounts of RNA oligonucleotides.

Wyatt JR, Chastain M, Puglisi JD.

Biotechniques. 1991 Dec;11(6):764-9.

PMID:
1809333
44.

Structural elements in RNA.

Chastain M, Tinoco I Jr.

Prog Nucleic Acid Res Mol Biol. 1991;41:131-77. Review. No abstract available.

PMID:
1715587
45.

Cryogenically preserved adult and juvenile goat mandibular condylar transplantation.

Bifano CA, Grellner T, Houston G, Farr SC, Ehler WJ, Cissik JH, Chastain M.

Oral Surg Oral Med Oral Pathol. 1990 Mar;69(3):291-8.

PMID:
2314855
46.

Transplantation of cryogenically preserved mandibular condyles in the adult and juvenile goat.

Bifano CA, Grellner T, Houston G, Farr SC, Ehler WJ, Cissik JH, Chastain M.

Aviat Space Environ Med. 1988 Nov;59(11 Pt 2):A76-80.

PMID:
3202807

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