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Items: 14


2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations.

Trzaska C, Amand S, Bailly C, Leroy C, Marchand V, Duvernois-Berthet E, Saliou JM, Benhabiles H, Werkmeister E, Chassat T, Guilbert R, Hannebique D, Mouray A, Copin MC, Moreau PA, Adriaenssens E, Kulozik A, Westhof E, Tulasne D, Motorin Y, Rebuffat S, Lejeune F.

Nat Commun. 2020 Mar 20;11(1):1509. doi: 10.1038/s41467-020-15140-z.


Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability.

Bokhari A, Jonchere V, Lagrange A, Bertrand R, Svrcek M, Marisa L, Buhard O, Greene M, Demidova A, Jia J, Adriaenssens E, Chassat T, Biard DS, Flejou JF, Lejeune F, Duval A, Collura A.

Oncogenesis. 2018 Sep 19;7(9):70. doi: 10.1038/s41389-018-0079-x.


The long non-coding RNA 91H increases aggressive phenotype of breast cancer cells and up-regulates H19/IGF2 expression through epigenetic modifications.

Vennin C, Spruyt N, Robin YM, Chassat T, Le Bourhis X, Adriaenssens E.

Cancer Lett. 2017 Jan 28;385:198-206. doi: 10.1016/j.canlet.2016.10.023. Epub 2016 Oct 22.


Relationship Between Pneumocystis carinii Burden and the Degree of Host Immunosuppression in an Airborne Transmission Experimental Model.

Khalife S, Chabé M, Gantois N, Audebert C, Pottier M, Hlais S, Pinçon C, Chassat T, Pierrot C, Khalife J, Aliouat-Denis CM, Aliouat el M.

J Eukaryot Microbiol. 2016 May;63(3):309-17. doi: 10.1111/jeu.12280. Epub 2015 Nov 24.


H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b.

Vennin C, Spruyt N, Dahmani F, Julien S, Bertucci F, Finetti P, Chassat T, Bourette RP, Le Bourhis X, Adriaenssens E.

Oncotarget. 2015 Oct 6;6(30):29209-23. doi: 10.18632/oncotarget.4976.


NGF-induced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib.

Aubert L, Guilbert M, Corbet C, Génot E, Adriaenssens E, Chassat T, Bertucci F, Daubon T, Magné N, Le Bourhis X, Toillon RA.

Oncotarget. 2015;6(12):9807-19.


Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model.

Benamrouz S, Conseil V, Chabé M, Praet M, Audebert C, Blervaque R, Guyot K, Gazzola S, Mouray A, Chassat T, Delaire B, Goetinck N, Gantois N, Osman M, Slomianny C, Dehennaut V, Lefebvre T, Viscogliosi E, Cuvelier C, Dei-Cas E, Creusy C, Certad G.

Dis Model Mech. 2014 Jun;7(6):693-700. doi: 10.1242/dmm.013292. Epub 2014 Mar 20.


Chronic ingestion of cadmium and lead alters the bioavailability of essential and heavy metals, gene expression pathways and genotoxicity in mouse intestine.

Breton J, Le Clère K, Daniel C, Sauty M, Nakab L, Chassat T, Dewulf J, Penet S, Carnoy C, Thomas P, Pot B, Nesslany F, Foligné B.

Arch Toxicol. 2013 Oct;87(10):1787-95. doi: 10.1007/s00204-013-1032-6. Epub 2013 Mar 17.


Cryptosporidium parvum infection in SCID mice infected with only one oocyst: qPCR assessment of parasite replication in tissues and development of digestive cancer.

Benamrouz S, Guyot K, Gazzola S, Mouray A, Chassat T, Delaire B, Chabé M, Gosset P, Viscogliosi E, Dei-Cas E, Creusy C, Conseil V, Certad G.

PLoS One. 2012;7(12):e51232. doi: 10.1371/journal.pone.0051232. Epub 2012 Dec 13.


Fulminant cryptosporidiosis after near-drowning: a human Cryptosporidium parvum strain implicated in invasive gastrointestinal adenocarcinoma and cholangiocarcinoma in an experimental model.

Certad G, Benamrouz S, Guyot K, Mouray A, Chassat T, Flament N, Delhaes L, Coiteux V, Delaire B, Praet M, Cuvelier C, Gosset P, Dei-Cas E, Creusy C.

Appl Environ Microbiol. 2012 Mar;78(6):1746-51. doi: 10.1128/AEM.06457-11. Epub 2012 Jan 13.


Fulminant cryptosporidiosis associated with digestive adenocarcinoma in SCID mice infected with Cryptosporidium parvum TUM1 strain.

Certad G, Creusy C, Guyot K, Mouray A, Chassat T, Delaire B, Pinon A, Sitja-Bobadilla A, Alvarez-Pellitero P, Praet M, Cuvelier C, Dei-Cas E.

Int J Parasitol. 2010 Nov;40(13):1469-75. doi: 10.1016/j.ijpara.2010.07.007. Epub 2010 Aug 12.


Development of Cryptosporidium parvum-induced gastrointestinal neoplasia in severe combined immunodeficiency (SCID) mice: severity of lesions is correlated with infection intensity.

Certad G, Creusy C, Ngouanesavanh T, Guyot K, Gantois N, Mouray A, Chassat T, Flament N, Fleurisse L, Pinon A, Delhaes L, Dei-Cas E.

Am J Trop Med Hyg. 2010 Feb;82(2):257-65. doi: 10.4269/ajtmh.2010.09-0309.


Cryptosporidium parvum, a potential cause of colic adenocarcinoma.

Certad G, Ngouanesavanh T, Guyot K, Gantois N, Chassat T, Mouray A, Fleurisse L, Pinon A, Cailliez JC, Dei-Cas E, Creusy C.

Infect Agent Cancer. 2007 Nov 21;2:22. doi: 10.1186/1750-9378-2-22.


Genotoxicity of ochratoxin A by Salmonella mutagenicity test after bioactivation by mouse kidney microsomes.

Obrecht-Pflumio S, Chassat T, Dirheimer G, Marzin D.

Mutat Res. 1999 Oct 29;446(1):95-102.


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