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Items: 1 to 50 of 402

1.

A Dynamic Situation with Uncertainty: Multiscale Modeling of Cardiac Thin-Filament Ca2+ Regulation.

Chase PB.

Biophys J. 2019 Sep 28. pii: S0006-3495(19)30817-3. doi: 10.1016/j.bpj.2019.09.030. [Epub ahead of print] No abstract available.

PMID:
31623882
2.

Cardiomyocyte nuclearity and ploidy: when is double trouble?

Landim-Vieira M, Schipper JM, Pinto JR, Chase PB.

J Muscle Res Cell Motil. 2019 Jul 17. doi: 10.1007/s10974-019-09545-7. [Epub ahead of print]

PMID:
31317457
3.

Elastic domains of giant proteins in striated muscle: Modeling compliance with rulers.

Chase PB.

J Gen Physiol. 2019 May 6;151(5):619-622. doi: 10.1085/jgp.201912345. Epub 2019 Apr 11. No abstract available.

PMID:
30975697
4.

Vital Directions for Pharmacy Education and Practice: Report of the 2017-18 Argus Commission.

Bootman JL, Boyle CJ, Chase P, DiPiro JT, Piascik P, Maine LL.

Am J Pharm Educ. 2018 Sep;82(7):7161. doi: 10.5688/ajpe7161.

5.

Identification of Antimalarial Inhibitors Using Late-Stage Gametocytes in a Phenotypic Live/Dead Assay.

Spicer TP, Gardiner DL, Schoenen FJ, Roy S, Griffin PR, Chase P, Scampavia L, Hodder P, Trenholme KR.

SLAS Discov. 2019 Jan;24(1):38-46. doi: 10.1177/2472555218796410. Epub 2018 Aug 24.

PMID:
30142014
6.

Identification of Novel, Structurally Diverse, Small Molecule Modulators of GPR119.

Nieto A, Fernández-Vega V, Spicer TP, Sturchler E, Adhikari P, Kennedy N, Mandat S, Chase P, Scampavia L, Bannister T, Hodder P, McDonald PH.

Assay Drug Dev Technol. 2018 Jul;16(5):278-288. doi: 10.1089/adt.2018.849.

7.

The Evolving State of Medical Device Cybersecurity.

Schwartz S, Ross A, Carmody S, Chase P, Coley SC, Connolly J, Petrozzino C, Zuk M.

Biomed Instrum Technol. 2018 Mar/Apr;52(2):103-111. doi: 10.2345/0899-8205-52.2.103. No abstract available.

PMID:
29558182
8.

Troponin through the looking-glass: emerging roles beyond regulation of striated muscle contraction.

Johnston JR, Chase PB, Pinto JR.

Oncotarget. 2017 Dec 4;9(1):1461-1482. doi: 10.18632/oncotarget.22879. eCollection 2018 Jan 2. Review.

9.

Aligning the AACP Strategic Engagement Agenda with Key Federal Priorities in Health: Report of the 2016-17 Argus Commission.

Crabtree B, Bootman JL, Boyle CJ, Chase P, Piascik P, Maine LL.

Am J Pharm Educ. 2017 Oct;81(8):S15. doi: 10.5688/ajpeS15.

10.

Systematic Changes to Help Parentsof Medically Complex Infants Manage Medical Expenses.

Carter J, Dwyer N, Roselund J, Cote K, Chase P, Martorana K, Gustafson K, Bergling E, Kamalia R, DeGrazia M.

Adv Neonatal Care. 2017 Dec;17(6):461-469. doi: 10.1097/ANC.0000000000000447.

PMID:
29077581
11.

Leveraging the IncuCyte Technology for Higher-Throughput and Automated Chemotaxis Assays for Target Validation and Compound Characterization.

Chen J, Ribeiro B, Li H, Myer L, Chase P, Surti N, Lippy J, Zhang L, Cvijic ME.

SLAS Discov. 2018 Feb;23(2):122-131. doi: 10.1177/2472555217733437. Epub 2017 Sep 28.

PMID:
28957636
12.

Exercise Oscillatory Ventilation: Interreviewer Agreement and a Novel Determination.

Brawner CA, Ehrman JK, Myers J, Chase P, Vainshelboim B, Farha S, Saval MA, McGuire R, Pozehl B, Keteyian SJ.

Med Sci Sports Exerc. 2018 Feb;50(2):369-374. doi: 10.1249/MSS.0000000000001423.

13.

The Cooccurrence of Obesity, Osteoporosis, and Sarcopenia in the Ovariectomized Rat: A Study for Modeling Osteosarcopenic Obesity in Rodents.

Ezzat-Zadeh Z, Kim JS, Chase PB, Arjmandi BH.

J Aging Res. 2017;2017:1454103. doi: 10.1155/2017/1454103. Epub 2017 Jun 1.

14.

Hypertrophic Cardiomyopathy Cardiac Troponin C Mutations Differentially Affect Slow Skeletal and Cardiac Muscle Regulation.

Veltri T, Landim-Vieira M, Parvatiyar MS, Gonzalez-Martinez D, Dieseldorff Jones KM, Michell CA, Dweck D, Landstrom AP, Chase PB, Pinto JR.

Front Physiol. 2017 Apr 20;8:221. doi: 10.3389/fphys.2017.00221. eCollection 2017.

15.

Examining the Foundation of AACP: Report of the 2015-16 Argus Commission.

Carter RA, Bootman JL, Chase PA, Crabtree BL, Piascik P, Maine LL.

Am J Pharm Educ. 2016 Nov 25;80(9):S18. doi: 10.5688/ajpe809S18. No abstract available.

16.

Will you still need me (Ca2+ , TnT, and DHPR), will you still cleave me (calpain), when I'm 64?

Pinto JR, Muller-Delp J, Chase PB.

Aging Cell. 2017 Apr;16(2):202-204. doi: 10.1111/acel.12560. Epub 2016 Dec 23. No abstract available.

17.

Development of an HTS-Compatible Assay for Discovery of Melanoma-Related Microphthalmia Transcription Factor Disruptors Using AlphaScreen Technology.

Wang J, Fang P, Chase P, Tshori S, Razin E, Spicer TP, Scampavia L, Hodder P, Guo M.

SLAS Discov. 2017 Jan;22(1):58-66. doi: 10.1177/1087057116675274. Epub 2016 Nov 11.

PMID:
27827304
18.

Efficacy of an Overnight Predictive Low-Glucose Suspend System in Relation to Hypoglycemia Risk Factors in Youth and Adults With Type 1 Diabetes.

Calhoun PM, Buckingham BA, Maahs DM, Hramiak I, Wilson DM, Aye T, Clinton P, Chase P, Messer L, Kollman C, Beck RW, Lum J; In Home Closed Loop Study Group.

J Diabetes Sci Technol. 2016 Nov 1;10(6):1216-1221. Print 2016 Nov. Erratum in: J Diabetes Sci Technol. 2017 Mar;11(2):NP1.

19.

Fluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin C.

Badr MA, Pinto JR, Davidson MW, Chase PB.

PLoS One. 2016 Oct 13;11(10):e0164222. doi: 10.1371/journal.pone.0164222. eCollection 2016.

20.
21.

An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C).

Swingle M, Volmar CH, Saldanha SA, Chase P, Eberhart C, Salter EA, D'Arcy B, Schroeder CE, Golden JE, Wierzbicki A, Hodder P, Honkanen RE.

SLAS Discov. 2017 Jan;22(1):21-31. doi: 10.1177/1087057116668852. Epub 2016 Sep 27.

PMID:
27628691
22.

Predictive Value of Fecal Calprotectin in Pediatric Graft-Versus-Host Disease.

Wadhwani SI, Nakayuenyongsuk W, Shinn L, Chase P, Kharbanda S, Bass D, Park KT.

J Pediatr Gastroenterol Nutr. 2016 Dec;63(6):e208-e209. No abstract available.

PMID:
27504814
23.

Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition.

Wood MR, Noetzel MJ, Tarr JC, Rodriguez AL, Lamsal A, Chang S, Foster JJ, Smith E, Chase P, Hodder PS, Engers DW, Niswender CM, Brandon NJ, Wood MW, Duggan ME, Conn PJ, Bridges TM, Lindsley CW.

Bioorg Med Chem Lett. 2016 Sep 1;26(17):4282-6. doi: 10.1016/j.bmcl.2016.07.042. Epub 2016 Jul 21.

24.

Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core.

Wood MR, Noetzel MJ, Engers JL, Bollinger KA, Melancon BJ, Tarr JC, Han C, West M, Gregro AR, Lamsal A, Chang S, Ajmera S, Smith E, Chase P, Hodder PS, Bubser M, Jones CK, Hopkins CR, Emmitte KA, Niswender CM, Wood MW, Duggan ME, Conn PJ, Bridges TM, Lindsley CW.

Bioorg Med Chem Lett. 2016 Jul 1;26(13):3029-3033. doi: 10.1016/j.bmcl.2016.05.010. Epub 2016 May 5.

25.

Fluorometric High-Throughput Screening Assay for Secreted Phospholipases A2 Using Phospholipid Vesicles.

Ewing H, Fernández-Vega V, Spicer TP, Chase P, Brown S, Scampavia L, Roush WR, Riley S, Rosen H, Hodder P, Lambeau G, Gelb MH.

J Biomol Screen. 2016 Aug;21(7):713-21. doi: 10.1177/1087057116646742. Epub 2016 May 4.

PMID:
27146384
26.

Role of cardiac troponin I carboxy terminal mobile domain and linker sequence in regulating cardiac contraction.

Meyer NL, Chase PB.

Arch Biochem Biophys. 2016 Jul 1;601:80-7. doi: 10.1016/j.abb.2016.03.010. Epub 2016 Mar 10.

27.

The functional significance of the last 5 residues of the C-terminus of cardiac troponin I.

Gilda JE, Xu Q, Martinez ME, Nguyen ST, Chase PB, Gomes AV.

Arch Biochem Biophys. 2016 Jul 1;601:88-96. doi: 10.1016/j.abb.2016.02.023. Epub 2016 Feb 23.

28.

Variables Measured During Cardiopulmonary Exercise Testing as Predictors of Mortality in Chronic Systolic Heart Failure.

Keteyian SJ, Patel M, Kraus WE, Brawner CA, McConnell TR, Piña IL, Leifer ES, Fleg JL, Blackburn G, Fonarow GC, Chase PJ, Piner L, Vest M, O'Connor CM, Ehrman JK, Walsh MN, Ewald G, Bensimhon D, Russell SD; HF-ACTION Investigators.

J Am Coll Cardiol. 2016 Feb 23;67(7):780-9. doi: 10.1016/j.jacc.2015.11.050. Erratum in: J Am Coll Cardiol. 2016 Apr 26;67(16):1979-80.

29.
30.

An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors.

Jambrina E, Cerne R, Smith E, Scampavia L, Cuadrado M, Findlay J, Krambis MJ, Wakulchik M, Chase P, Brunavs M, Burris KD, Gallagher P, Spicer TP, Ursu D.

J Biomol Screen. 2016 Jun;21(5):468-79. doi: 10.1177/1087057116628437. Epub 2016 Feb 2.

PMID:
26838761
31.

An Automated Miniaturized Method to Perform and Analyze Antimicrobial Drug Synergy Assays.

Chase P, Enogieru I, Madoux F, Bishop E, Beer J, Scampavia L, Spicer T.

Assay Drug Dev Technol. 2016 Jan-Feb;14(1):58-66. doi: 10.1089/adt.2015.672. Epub 2015 Dec 15.

32.

Differential physiological and behavioral cues observed in individuals smoking botanical marijuana versus synthetic cannabinoid drugs.

Chase PB, Hawkins J, Mosier J, Jimenez E, Boesen K, Logan BK, Walter FG.

Clin Toxicol (Phila). 2016;54(1):14-9. doi: 10.3109/15563650.2015.1101769.

PMID:
26653952
33.

First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis.

Palde PB, Bhaskar A, Pedró Rosa LE, Madoux F, Chase P, Gupta V, Spicer T, Scampavia L, Singh A, Carroll KS.

ACS Chem Biol. 2016 Jan 15;11(1):172-84. doi: 10.1021/acschembio.5b00517. Epub 2015 Nov 11.

34.

Comparison of Estimations Versus Measured Oxygen Consumption at Rest in Patients With Heart Failure and Reduced Ejection Fraction Who Underwent Right-Sided Heart Catheterization.

Chase PJ, Davis PG, Wideman L, Starnes JW, Schulz MR, Bensimhon DR.

Am J Cardiol. 2015 Dec 1;116(11):1724-30. doi: 10.1016/j.amjcard.2015.08.051. Epub 2015 Sep 11.

PMID:
26443561
35.

Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle.

Sanders MA, Madoux F, Mladenovic L, Zhang H, Ye X, Angrish M, Mottillo EP, Caruso JA, Halvorsen G, Roush WR, Chase P, Hodder P, Granneman JG.

Cell Metab. 2015 Nov 3;22(5):851-60. doi: 10.1016/j.cmet.2015.08.023. Epub 2015 Sep 24.

36.

Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4).

Smith E, Chase P, Niswender CM, Utley TJ, Sheffler DJ, Noetzel MJ, Lamsal A, Wood MR, Conn PJ, Lindsley CW, Madoux F, Acosta M, Scampavia L, Spicer T, Hodder P.

J Biomol Screen. 2015 Aug;20(7):858-68. doi: 10.1177/1087057115581770. Epub 2015 Apr 15.

37.

Development of a Novel, Orthosteric M5 Antagonist Possessing a High Degree of Muscarinic Subtype Selectivity.

Gentry PR, Kokubo M, Bridges TM, Daniels JS, Niswender CM, Smith E, Chase P, Hodder PS, Rosen H, Conn PJ, Engers J, Brewer KA, Wood MR, Lindsley CW.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 15 [updated 2015 Feb 11].

38.

Development of the First CNS penetrant M5 Positive Allosteric Modulator (PAM) Based on a Novel, non-Isatin Core.

Gentry PR, Kokubo M, Bridges TM, Daniels JS, Niswender CM, Smith E, Chase P, Hodder PS, Rosen H, Conn PJ, Engers J, Brewer KA, Lindsley CW, Wood MR.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 15 [updated 2015 Feb 11].

39.

Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1.

Ting PY, Damoiseaux R, Titz B, Bradley KA, Graeber TG, Fernández-Vega V, Bannister TD, Chase P, Nair R, Scampavia L, Hodder P, Spicer TP, Colicelli J.

PLoS One. 2015 Mar 26;10(3):e0121833. doi: 10.1371/journal.pone.0121833. eCollection 2015.

40.

Using relational developmental systems theory to link program goals, activities, and outcomes: the sample case of the 4-H Study of Positive Youth Development.

Lerner RM, Wang J, Chase PA, Gutierrez AS, Harris EM, Rubin RO, Yalin C.

New Dir Youth Dev. 2014 Dec;2014(144):17-30. doi: 10.1002/yd.20110.

PMID:
25537347
41.

Gila monster (Heloderma suspectum) envenomation: Descriptive analysis of calls to United States Poison Centers with focus on Arizona cases.

French R, Brooks D, Ruha AM, Shirazi F, Chase P, Boesen K, Walter F.

Clin Toxicol (Phila). 2015 Jan;53(1):60-70. doi: 10.3109/15563650.2014.988791. Epub 2014 Dec 16. Review.

PMID:
25511795
42.

Inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase.

Schoenen FJ, Whipple D, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Hodder P, Mathew R, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Weiner WS, Aubé J, Rosen H, White EL, Gardiner DL, Dalton JP.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 12 [updated 2014 Sep 18].

43.

Development of the First Potent, Selective and CNS penetrant M5 Negative Allosteric Modulator (NAM).

Gentry PR, Kokubo M, Bridges TM, Daniels JS, Niswender CM, Smith E, Chase P, Hodder PS, Rosen H, Conn PJ, Engers J, Brewer KA, Wood MR, Lindsley CW.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 9 [updated 2014 Sep 18].

44.

Additive prognostic value of a cardiopulmonary exercise test score in patients with heart failure and intermediate risk.

Ritt LE, Myers J, Stein R, Arena R, Guazzi M, Chase P, Bensimhon D, Ashley E, Cahalin LP, Forman DE.

Int J Cardiol. 2015 Jan 15;178:262-4. doi: 10.1016/j.ijcard.2014.10.025. Epub 2014 Oct 12. No abstract available.

PMID:
25464266
45.

Discovery and SAR of muscarinic receptor subtype 1 (M1) allosteric activators from a molecular libraries high throughput screen. Part 1: 2,5-dibenzyl-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones as positive allosteric modulators.

Han C, Chatterjee A, Noetzel MJ, Panarese JD, Smith E, Chase P, Hodder P, Niswender C, Conn PJ, Lindsley CW, Stauffer SR.

Bioorg Med Chem Lett. 2015 Jan 15;25(2):384-8. doi: 10.1016/j.bmcl.2014.11.011. Epub 2014 Nov 18.

46.

Access, affordability, accountability: 2013-2014 President-elect address to the 2014 AACP house of delegates.

Chase PA.

Am J Pharm Educ. 2014 Oct 15;78(8):S7. doi: 10.5688/ajpe788S7. No abstract available.

47.

High-throughput screening for small molecule modulators of motor protein Kinesin.

Kadakkuzha BM, Spicer TP, Chase P, Richman JB, Hodder P, Puthanveettil SV.

Assay Drug Dev Technol. 2014 Oct;12(8):470-80. doi: 10.1089/adt.2014.579.

PMID:
25383721
48.

Frequency dependence of power and its implications for contractile function of muscle fibers from the digital flexors of horses.

Butcher MT, Bertram JE, Syme DA, Hermanson JW, Chase PB.

Physiol Rep. 2014 Oct 7;2(10). pii: e12174. doi: 10.14814/phy2.12174. Print 2014 Oct 1.

49.

ML368 Identification of Imidazopyridines as Selective Inhibitors of the Cytochrome P450 Enzyme CYP3A4.

Cameron M, Kamenecka T, Madoux F, Chase P, Roush W, Hodder P, Griffin PR.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 15 [updated 2014 Sep 18].

50.

Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase.

Schoenen FJ, Weiner WS, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Ghosh P, Hodder P, Krise JP, Matharu DS, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Whipple D, Aubé J, Rosen H, White EL, Dalton JP, Gardiner DL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 12 [updated 2014 Sep 18].

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