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Items: 7

1.

NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models.

Charych DH, Hoch U, Langowski JL, Lee SR, Addepalli MK, Kirk PB, Sheng D, Liu X, Sims PW, VanderVeen LA, Ali CF, Chang TK, Konakova M, Pena RL, Kanhere RS, Kirksey YM, Ji C, Wang Y, Huang J, Sweeney TD, Kantak SS, Doberstein SK.

Clin Cancer Res. 2016 Feb 1;22(3):680-90. doi: 10.1158/1078-0432.CCR-15-1631.

2.

Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells.

Charych DH, Coyne M, Yabannavar A, Narberes J, Chow S, Wallroth M, Shafer C, Walter AO.

J Cell Biochem. 2008 Jun 1;104(3):1075-86. doi: 10.1002/jcb.21698.

PMID:
18286467
3.

Cleavable hydrophilic linker for one-bead-one-compound sequencing of oligomer libraries by tandem mass spectrometry.

Paulick MG, Hart KM, Brinner KM, Tjandra M, Charych DH, Zuckermann RN.

J Comb Chem. 2006 May-Jun;8(3):417-26.

PMID:
16677012
4.

Incorporation of unprotected heterocyclic side chains into peptoid oligomers via solid-phase submonomer synthesis.

Burkoth TS, Fafarman AT, Charych DH, Connolly MD, Zuckermann RN.

J Am Chem Soc. 2003 Jul 23;125(29):8841-5.

PMID:
12862480
5.

Design and synthesis of novel glycopolythiophene assemblies for colorimetric detection of influenza virus and E. coli.

Baek MG, Stevens RC, Charych DH.

Bioconjug Chem. 2000 Nov-Dec;11(6):777-88.

PMID:
11087325
6.

Carbohydrates in an acidic multivalent assembly: nanomolar P-selectin inhibitors.

Spevak W, Foxall C, Charych DH, Dasgupta F, Nagy JO.

J Med Chem. 1996 Mar 1;39(5):1018-20. No abstract available.

PMID:
8676335
7.

Direct colorimetric detection of a receptor-ligand interaction by a polymerized bilayer assembly.

Charych DH, Nagy JO, Spevak W, Bednarski MD.

Science. 1993 Jul 30;261(5121):585-8. Erratum in: Science 1993 Sep 10;261(5127):1375.

PMID:
8342021

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