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Items: 32


Excessive rDNA Transcription Drives the Disruption in Nuclear Homeostasis during Entry into Senescence in Budding Yeast.

Morlot S, Song J, Léger-Silvestre I, Matifas A, Gadal O, Charvin G.

Cell Rep. 2019 Jul 9;28(2):408-422.e4. doi: 10.1016/j.celrep.2019.06.032.


Self-Learning Microfluidic Platform for Single-Cell Imaging and Classification in Flow.

Constantinou I, Jendrusch M, Aspert T, Görlitz F, Schulze A, Charvin G, Knop M.

Micromachines (Basel). 2019 May 9;10(5). pii: E311. doi: 10.3390/mi10050311.


Corrigendum: Adaptation to DNA damage checkpoint in senescent telomerase-negative cells promotes genome instability.

Coutelier H, Xu Z, Morisse MC, Lhuillier-Akakpo M, Pelet S, Charvin G, Dubrana K, Teixeira MT.

Genes Dev. 2019 Mar 1;33(5-6):378. doi: 10.1101/gad.324459.119. No abstract available.


Adaptation to DNA damage checkpoint in senescent telomerase-negative cells promotes genome instability.

Coutelier H, Xu Z, Morisse MC, Lhuillier-Akakpo M, Pelet S, Charvin G, Dubrana K, Teixeira MT.

Genes Dev. 2018 Dec 1;32(23-24):1499-1513. doi: 10.1101/gad.318485.118. Epub 2018 Nov 21. Erratum in: Genes Dev. 2019 Mar 1;33(5-6):378.


Controllable stress patterns over multi-generation timescale in microfluidic devices.

Goulev Y, Matifas A, Charvin G.

Methods Cell Biol. 2018;147:29-40. doi: 10.1016/bs.mcb.2018.07.003. Epub 2018 Aug 9.


Multiple inputs ensure yeast cell size homeostasis during cell cycle progression.

Garmendia-Torres C, Tassy O, Matifas A, Molina N, Charvin G.

Elife. 2018 Jul 4;7. pii: e34025. doi: 10.7554/eLife.34025.


Nonlinear feedback drives homeostatic plasticity in H2O2 stress response.

Goulev Y, Morlot S, Matifas A, Huang B, Molin M, Toledano MB, Charvin G.

Elife. 2017 Apr 18;6. pii: e23971. doi: 10.7554/eLife.23971.


Kinetics of Formation and Asymmetrical Distribution of Hsp104-Bound Protein Aggregates in Yeast.

Paoletti C, Quintin S, Matifas A, Charvin G.

Biophys J. 2016 Apr 12;110(7):1605-1614. doi: 10.1016/j.bpj.2016.02.034.


Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages.

Xu Z, Fallet E, Paoletti C, Fehrmann S, Charvin G, Teixeira MT.

Nat Commun. 2015 Jul 9;6:7680. doi: 10.1038/ncomms8680.


Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development.

Heckel E, Boselli F, Roth S, Krudewig A, Belting HG, Charvin G, Vermot J.

Curr Biol. 2015 May 18;25(10):1354-61. doi: 10.1016/j.cub.2015.03.038. Epub 2015 May 7.


A quantitative approach to study endothelial cilia bending stiffness during blood flow mechanodetection in vivo.

Boselli F, Goetz JG, Charvin G, Vermot J.

Methods Cell Biol. 2015;127:161-73. doi: 10.1016/bs.mcb.2015.01.006. Epub 2015 Mar 7.


In silico control of biomolecular processes.

Uhlendorf J, Miermont A, Delaveau T, Charvin G, Fages F, Bottani S, Hersen P, Batt G.

Methods Mol Biol. 2015;1244:277-85. doi: 10.1007/978-1-4939-1878-2_13.


A memory system of negative polarity cues prevents replicative aging.

Meitinger F, Khmelinskii A, Morlot S, Kurtulmus B, Palani S, Andres-Pons A, Hub B, Knop M, Charvin G, Pereira G.

Cell. 2014 Nov 20;159(5):1056-1069. doi: 10.1016/j.cell.2014.10.014. Epub 2014 Nov 13.


Endothelial cilia mediate low flow sensing during zebrafish vascular development.

Goetz JG, Steed E, Ferreira RR, Roth S, Ramspacher C, Boselli F, Charvin G, Liebling M, Wyart C, Schwab Y, Vermot J.

Cell Rep. 2014 Mar 13;6(5):799-808. doi: 10.1016/j.celrep.2014.01.032. Epub 2014 Feb 20.


Aging yeast cells undergo a sharp entry into senescence unrelated to the loss of mitochondrial membrane potential.

Fehrmann S, Paoletti C, Goulev Y, Ungureanu A, Aguilaniu H, Charvin G.

Cell Rep. 2013 Dec 26;5(6):1589-99. doi: 10.1016/j.celrep.2013.11.013. Epub 2013 Dec 12.


Pulse propagation by a capacitive mechanism drives embryonic blood flow.

Anton H, Harlepp S, Ramspacher C, Wu D, Monduc F, Bhat S, Liebling M, Paoletti C, Charvin G, Freund JB, Vermot J.

Development. 2013 Nov;140(21):4426-34. doi: 10.1242/dev.096768. Epub 2013 Oct 2.


Comparison of DNA decatenation by Escherichia coli topoisomerase IV and topoisomerase III: implications for non-equilibrium topology simplification.

Seol Y, Hardin AH, Strub MP, Charvin G, Neuman KC.

Nucleic Acids Res. 2013 Apr;41(8):4640-9. doi: 10.1093/nar/gkt136. Epub 2013 Mar 4.


Long-term model predictive control of gene expression at the population and single-cell levels.

Uhlendorf J, Miermont A, Delaveau T, Charvin G, Fages F, Bottani S, Batt G, Hersen P.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14271-6. doi: 10.1073/pnas.1206810109. Epub 2012 Aug 14.


Ultrasensitivity and positive feedback to promote sharp mitotic entry.

Goulev Y, Charvin G.

Mol Cell. 2011 Feb 4;41(3):243-4. doi: 10.1016/j.molcel.2011.01.016.


[Nucleosome-depleted regions in promoters: consequences on robustness of transcriptional activation].

Bai L, Charvin G.

Med Sci (Paris). 2010 Dec;26(12):1035-7. doi: 10.1051/medsci/201026121035. French. No abstract available.


Measuring the growth rate of cells, one at a time.

Charvin G.

Nat Methods. 2010 May;7(5):363. doi: 10.1038/nmeth0510-363. No abstract available.


Nucleosome-depleted regions in cell-cycle-regulated promoters ensure reliable gene expression in every cell cycle.

Bai L, Charvin G, Siggia ED, Cross FR.

Dev Cell. 2010 Apr 20;18(4):544-55. doi: 10.1016/j.devcel.2010.02.007.


Origin of irreversibility of cell cycle start in budding yeast.

Charvin G, Oikonomou C, Siggia ED, Cross FR.

PLoS Biol. 2010 Jan 19;8(1):e1000284. doi: 10.1371/journal.pbio.1000284. Erratum in: PLoS Biol. 2011 Jul;9(7). doi:10.1371/annotation/90916531-1b34-4eb5-92a9-a7f8c5d72318.


Long-term imaging in microfluidic devices.

Charvin G, Oikonomou C, Cross F.

Methods Mol Biol. 2010;591:229-42. doi: 10.1007/978-1-60761-404-3_14.


Mechanisms of chiral discrimination by topoisomerase IV.

Neuman KC, Charvin G, Bensimon D, Croquette V.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6986-91. doi: 10.1073/pnas.0900574106. Epub 2009 Apr 9.


Forced periodic expression of G1 cyclins phase-locks the budding yeast cell cycle.

Charvin G, Cross FR, Siggia ED.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6632-7. doi: 10.1073/pnas.0809227106. Epub 2009 Apr 3.


A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells.

Charvin G, Cross FR, Siggia ED.

PLoS One. 2008 Jan 23;3(1):e1468. doi: 10.1371/journal.pone.0001468.


Bistability and hysteresis in epigenetic regulation of the lactose operon. Since Delbrück, a long series of ignored models.

Laurent M, Charvin G, Guespin-Michel J.

Cell Mol Biol (Noisy-le-grand). 2005 Dec 14;51(7):583-94.


Tracking topoisomerase activity at the single-molecule level.

Charvin G, Strick TR, Bensimon D, Croquette V.

Annu Rev Biophys Biomol Struct. 2005;34:201-19. Review.


Topoisomerase IV bends and overtwists DNA upon binding.

Charvin G, Strick TR, Bensimon D, Croquette V.

Biophys J. 2005 Jul;89(1):384-92. Epub 2005 Apr 29.


Braiding DNA: experiments, simulations, and models.

Charvin G, Vologodskii A, Bensimon D, Croquette V.

Biophys J. 2005 Jun;88(6):4124-36. Epub 2005 Mar 18.


Single-molecule study of DNA unlinking by eukaryotic and prokaryotic type-II topoisomerases.

Charvin G, Bensimon D, Croquette V.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9820-5. Epub 2003 Aug 5.

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