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Items: 1 to 50 of 124

1.

RNase Y-mediated regulation of the streptococcal pyrogenic exotoxin B.

Broglia L, Materne S, Lécrivain AL, Hahnke K, Le Rhun A, Charpentier E.

RNA Biol. 2018 Oct 5:1-12. doi: 10.1080/15476286.2018.1532253. [Epub ahead of print]

PMID:
30290721
2.

Contribution of Fluorescence Techniques in Determining the Efficiency of the Non-thermal Plasma Treatment.

Carré G, Charpentier E, Audonnet S, Terryn C, Boudifa M, Doliwa C, Belgacem ZB, Gangloff SC, Gelle MP.

Front Microbiol. 2018 Sep 10;9:2171. doi: 10.3389/fmicb.2018.02171. eCollection 2018.

3.

A threshold value of 3.5 mm of passive anterior tibial subluxation on MRI is highly specific for complete ACL tears.

Hardy A, Klouche S, Szarzynski P, Charpentier E, Beranger JS, Bauer T, Rousselin B, Judet O, Hardy P.

Knee Surg Sports Traumatol Arthrosc. 2018 Sep 22. doi: 10.1007/s00167-018-5159-0. [Epub ahead of print]

PMID:
30244342
4.

Presumption of pericardial endometriosis using MRI: Case report and review of the literature.

Charpentier E, Petit E, Beranger S, Azarine A.

J Gynecol Obstet Hum Reprod. 2018 Jul 4. pii: S2468-7847(18)30223-X. doi: 10.1016/j.jogoh.2018.06.009. [Epub ahead of print]

PMID:
29981475
5.

Quantitative PCR (qPCR) Detection of Mucorales DNA in Bronchoalveolar Lavage Fluid To Diagnose Pulmonary Mucormycosis.

Scherer E, Iriart X, Bellanger AP, Dupont D, Guitard J, Gabriel F, Cassaing S, Charpentier E, Guenounou S, Cornet M, Botterel F, Rocchi S, Berceanu A, Millon L.

J Clin Microbiol. 2018 Jul 26;56(8). pii: e00289-18. doi: 10.1128/JCM.00289-18. Print 2018 Aug.

PMID:
29875192
6.

Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication?

Tsatsaronis JA, Franch-Arroyo S, Resch U, Charpentier E.

Trends Microbiol. 2018 May;26(5):401-410. doi: 10.1016/j.tim.2018.02.009. Epub 2018 Mar 13. Review.

PMID:
29548832
7.

The Biology of CRISPR-Cas: Backward and Forward.

Hille F, Richter H, Wong SP, Bratovič M, Ressel S, Charpentier E.

Cell. 2018 Mar 8;172(6):1239-1259. doi: 10.1016/j.cell.2017.11.032. Review.

PMID:
29522745
8.

Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/- Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice.

Bézie S, Meistermann D, Boucault L, Kilens S, Zoppi J, Autrusseau E, Donnart A, Nerrière-Daguin V, Bellier-Waast F, Charpentier E, Duteille F, David L, Anegon I, Guillonneau C.

Front Immunol. 2018 Jan 31;8:2014. doi: 10.3389/fimmu.2017.02014. eCollection 2017.

9.

Spotlight on… Emmanuelle Charpentier.

Charpentier E.

FEMS Microbiol Lett. 2018 Feb 1;365(4). doi: 10.1093/femsle/fnx271. No abstract available.

PMID:
29390135
10.

Parallel derivation of isogenic human primed and naive induced pluripotent stem cells.

Kilens S, Meistermann D, Moreno D, Chariau C, Gaignerie A, Reignier A, Lelièvre Y, Casanova M, Vallot C, Nedellec S, Flippe L, Firmin J, Song J, Charpentier E, Lammers J, Donnart A, Marec N, Deb W, Bihouée A, Le Caignec C, Pecqueur C, Redon R, Barrière P, Bourdon J, Pasque V, Soumillon M, Mikkelsen TS, Rougeulle C, Fréour T, David L; Milieu Intérieur Consortium.

Nat Commun. 2018 Jan 24;9(1):360. doi: 10.1038/s41467-017-02107-w.

11.

Functionally Convergent B Cell Receptor Sequences in Transgenic Rats Expressing a Human B Cell Repertoire in Response to Tetanus Toxoid and Measles Antigens.

Bürckert JP, Dubois ARSX, Faison WJ, Farinelle S, Charpentier E, Sinner R, Wienecke-Baldacchino A, Muller CP.

Front Immunol. 2017 Dec 22;8:1834. doi: 10.3389/fimmu.2017.01834. eCollection 2017.

12.

IgG antibody prevalence suggests high immunization needs in newcomers to Luxembourg, 2012.

Hübschen JM, Charpentier E, Weicherding P, Muller CP.

Vaccine. 2018 Feb 1;36(6):899-905. doi: 10.1016/j.vaccine.2017.12.041. Epub 2018 Jan 3.

PMID:
29306505
13.

Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications.

Labuhn M, Adams FF, Ng M, Knoess S, Schambach A, Charpentier EM, Schwarzer A, Mateo JL, Klusmann JH, Heckl D.

Nucleic Acids Res. 2018 Feb 16;46(3):1375-1385. doi: 10.1093/nar/gkx1268.

14.

De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.

Küry S, van Woerden GM, Besnard T, Proietti Onori M, Latypova X, Towne MC, Cho MT, Prescott TE, Ploeg MA, Sanders S, Stessman HAF, Pujol A, Distel B, Robak LA, Bernstein JA, Denommé-Pichon AS, Lesca G, Sellars EA, Berg J, Carré W, Busk ØL, van Bon BWM, Waugh JL, Deardorff M, Hoganson GE, Bosanko KB, Johnson DS, Dabir T, Holla ØL, Sarkar A, Tveten K, de Bellescize J, Braathen GJ, Terhal PA, Grange DK, van Haeringen A, Lam C, Mirzaa G, Burton J, Bhoj EJ, Douglas J, Santani AB, Nesbitt AI, Helbig KL, Andrews MV, Begtrup A, Tang S, van Gassen KLI, Juusola J, Foss K, Enns GM, Moog U, Hinderhofer K, Paramasivam N, Lincoln S, Kusako BH, Lindenbaum P, Charpentier E, Nowak CB, Cherot E, Simonet T, Ruivenkamp CAL, Hahn S, Brownstein CA, Xia F, Schmitt S, Deb W, Bonneau D, Nizon M, Quinquis D, Chelly J, Rudolf G, Sanlaville D, Parent P, Gilbert-Dussardier B, Toutain A, Sutton VR, Thies J, Peart-Vissers LELM, Boisseau P, Vincent M, Grabrucker AM, Dubourg C; Undiagnosed Diseases Network, Tan WH, Verbeek NE, Granzow M, Santen GWE, Shendure J, Isidor B, Pasquier L, Redon R, Yang Y, State MW, Kleefstra T, Cogné B; GEM HUGO; Deciphering Developmental Disorders Study, Petrovski S, Retterer K, Eichler EE, Rosenfeld JA, Agrawal PB, Bézieau S, Odent S, Elgersma Y, Mercier S.

Am J Hum Genet. 2017 Nov 2;101(5):768-788. doi: 10.1016/j.ajhg.2017.10.003.

15.

An intermediate level of CD161 expression defines a novel activated, inflammatory, and pathogenic subset of CD8+ T cells involved in multiple sclerosis.

Nicol B, Salou M, Vogel I, Garcia A, Dugast E, Morille J, Kilens S, Charpentier E, Donnart A, Nedellec S, Jacq-Foucher M, Le Frère F, Wiertlewski S, Bourreille A, Brouard S, Michel L, David L, Gourraud PA, Degauque N, Nicot AB, Berthelot L, Laplaud DA.

J Autoimmun. 2018 Mar;88:61-74. doi: 10.1016/j.jaut.2017.10.005. Epub 2017 Oct 18.

16.

Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity.

Hurwitz JL, Jones BG, Charpentier E, Woodland DL.

Viral Immunol. 2017 Nov;30(9):628-632. doi: 10.1089/vim.2017.0099. Epub 2017 Oct 13.

PMID:
29028182
17.

A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum.

Fabiani FD, Renault TT, Peters B, Dietsche T, Gálvez EJC, Guse A, Freier K, Charpentier E, Strowig T, Franz-Wachtel M, Macek B, Wagner S, Hensel M, Erhardt M.

PLoS Biol. 2017 Aug 3;15(8):e2002267. doi: 10.1371/journal.pbio.2002267. eCollection 2017 Aug.

18.

Functional Diversity of AAA+ Protease Complexes in Bacillus subtilis.

Elsholz AKW, Birk MS, Charpentier E, Turgay K.

Front Mol Biosci. 2017 Jul 12;4:44. doi: 10.3389/fmolb.2017.00044. eCollection 2017. Review.

19.

Added Value of Next-Generation Sequencing for Multilocus Sequence Typing Analysis of a Pneumocystis jirovecii Pneumonia Outbreak1.

Charpentier E, Garnaud C, Wintenberger C, Bailly S, Murat JB, Rendu J, Pavese P, Drouet T, Augier C, Malvezzi P, Thiébaut-Bertrand A, Mallaret MR, Epaulard O, Cornet M, Larrat S, Maubon D.

Emerg Infect Dis. 2017 Aug;23(8):1237-1245. doi: 10.3201/eid2308.161295.

20.

Innovative non-thermal plasma disinfection process inside sealed bags: Assessment of bactericidal and sporicidal effectiveness in regard to current sterilization norms.

Ben Belgacem Z, Carré G, Charpentier E, Le-Bras F, Maho T, Robert E, Pouvesle JM, Polidor F, Gangloff SC, Boudifa M, Gelle MP.

PLoS One. 2017 Jun 29;12(6):e0180183. doi: 10.1371/journal.pone.0180183. eCollection 2017.

21.

Killer Immunoglobulin-Like Receptor Allele Determination Using Next-Generation Sequencing Technology.

Maniangou B, Legrand N, Alizadeh M, Guyet U, Willem C, David G, Charpentier E, Walencik A, Retière C, Gagne K.

Front Immunol. 2017 May 19;8:547. doi: 10.3389/fimmu.2017.00547. eCollection 2017.

22.

CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo.

Reimer J, Knöß S, Labuhn M, Charpentier EM, Göhring G, Schlegelberger B, Klusmann JH, Heckl D.

Haematologica. 2017 Sep;102(9):1558-1566. doi: 10.3324/haematol.2017.164046. Epub 2017 Jun 1.

23.

A phase 1b study of isatuximab plus lenalidomide and dexamethasone for relapsed/refractory multiple myeloma.

Martin T, Baz R, Benson DM, Lendvai N, Wolf J, Munster P, Lesokhin AM, Wack C, Charpentier E, Campana F, Vij R.

Blood. 2017 Jun 22;129(25):3294-3303. doi: 10.1182/blood-2016-09-740787. Epub 2017 May 8.

24.

Asymptomatic aortic coarctation diagnosed because of large abdominal arterial collateral.

Charpentier E, Bacquet D, Pontnau F, Azarine A.

Vasc Med. 2017 Aug;22(4):347-348. doi: 10.1177/1358863X17692423. Epub 2017 Mar 19. No abstract available.

PMID:
28466680
25.

Switchable Cas9.

Richter F, Fonfara I, Gelfert R, Nack J, Charpentier E, Möglich A.

Curr Opin Biotechnol. 2017 Dec;48:119-126. doi: 10.1016/j.copbio.2017.03.025. Epub 2017 Apr 26. Review.

PMID:
28456061
26.

Bacterial flagella grow through an injection-diffusion mechanism.

Renault TT, Abraham AO, Bergmiller T, Paradis G, Rainville S, Charpentier E, Guet CC, Tu Y, Namba K, Keener JP, Minamino T, Erhardt M.

Elife. 2017 Mar 6;6. pii: e23136. doi: 10.7554/eLife.23136.

27.

Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells.

Picarda E, Bézie S, Boucault L, Autrusseau E, Kilens S, Meistermann D, Martinet B, Daguin V, Donnart A, Charpentier E, David L, Anegon I, Guillonneau C.

JCI Insight. 2017 Feb 9;2(3):e90088. doi: 10.1172/jci.insight.90088.

28.

Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III in Streptococcus pyogenes.

Le Rhun A, Lécrivain AL, Reimegård J, Proux-Wéra E, Broglia L, Della Beffa C, Charpentier E.

Nucleic Acids Res. 2017 Mar 17;45(5):2329-2340. doi: 10.1093/nar/gkw1316.

29.

Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase.

Eggenschwiler R, Moslem M, Fráguas MS, Galla M, Papp O, Naujock M, Fonfara I, Gensch I, Wähner A, Beh-Pajooh A, Mussolino C, Tauscher M, Steinemann D, Wegner F, Petri S, Schambach A, Charpentier E, Cathomen T, Cantz T.

Sci Rep. 2016 Dec 2;6:38198. doi: 10.1038/srep38198.

30.

Grouped Cases of Pulmonary Pneumocystosis After Solid Organ Transplantation: Advantages of Coordination by an Infectious Diseases Unit for Overall Management and Epidemiological Monitoring.

Wintenberger C, Maubon D, Charpentier E, Rendu J, Pavese P, Augier C, Malvezzi P, Camara B, Mallaret MR, Bouillet L, Epaulard O.

Infect Control Hosp Epidemiol. 2017 Feb;38(2):179-185. doi: 10.1017/ice.2016.274. Epub 2016 Nov 28.

PMID:
27890037
31.

A Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A Streptococcus.

Resch U, Tsatsaronis JA, Le Rhun A, Stübiger G, Rohde M, Kasvandik S, Holzmeister S, Tinnefeld P, Wai SN, Charpentier E.

MBio. 2016 Nov 1;7(6). pii: e00207-16. doi: 10.1128/mBio.00207-16.

32.

Engineering of temperature- and light-switchable Cas9 variants.

Richter F, Fonfara I, Bouazza B, Schumacher CH, Bratovič M, Charpentier E, Möglich A.

Nucleic Acids Res. 2016 Nov 16;44(20):10003-10014. Epub 2016 Oct 15.

33.

CRISPR-Cas: biology, mechanisms and relevance.

Hille F, Charpentier E.

Philos Trans R Soc Lond B Biol Sci. 2016 Nov 5;371(1707). pii: 20150496. doi: 10.1098/rstb.2015.0496. Review.

34.

[Congestive heart failure: Treatment with ultrafiltration].

Taron-Brocard C, Looten V, Fahlgren B, Charpentier E, Guillevin L, Barna A.

Ann Cardiol Angeiol (Paris). 2016 Sep;65(4):240-4. doi: 10.1016/j.ancard.2016.04.028. Epub 2016 Jun 22. Review. French.

PMID:
27344095
35.

Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes.

Labenski V, Suerth JD, Barczak E, Heckl D, Levy C, Bernadin O, Charpentier E, Williams DA, Fehse B, Verhoeyen E, Schambach A.

Biomaterials. 2016 Aug;97:97-109. doi: 10.1016/j.biomaterials.2016.04.019. Epub 2016 Apr 26.

PMID:
27162078
36.

The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.

Fonfara I, Richter H, Bratovič M, Le Rhun A, Charpentier E.

Nature. 2016 Apr 28;532(7600):517-21. doi: 10.1038/nature17945. Epub 2016 Apr 20.

PMID:
27096362
37.

Adaptation in CRISPR-Cas Systems.

Sternberg SH, Richter H, Charpentier E, Qimron U.

Mol Cell. 2016 Mar 17;61(6):797-808. doi: 10.1016/j.molcel.2016.01.030. Epub 2016 Mar 3. Review.

38.

Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I.

Daumy X, Amarouch MY, Lindenbaum P, Bonnaud S, Charpentier E, Bianchi B, Nafzger S, Baron E, Fouchard S, Thollet A, Kyndt F, Barc J, Le Scouarnec S, Makita N, Le Marec H, Dina C, Gourraud JB, Probst V, Abriel H, Redon R, Schott JJ.

Int J Cardiol. 2016 Mar 15;207:349-58. doi: 10.1016/j.ijcard.2016.01.052. Epub 2016 Jan 11.

PMID:
26820365
39.

Meta-analytic estimation of measurement variability and assessment of its impact on decision-making: the case of perioperative haemoglobin concentration monitoring.

Charpentier E, Looten V, Fahlgren B, Barna A, Guillevin L.

BMC Med Res Methodol. 2016 Jan 19;16:7. doi: 10.1186/s12874-016-0107-5.

40.

De Novo Truncating Mutations in the Kinetochore-Microtubules Attachment Gene CHAMP1 Cause Syndromic Intellectual Disability.

Isidor B, Küry S, Rosenfeld JA, Besnard T, Schmitt S, Joss S, Davies SJ, Lebel RR, Henderson A, Schaaf CP, Streff HE, Yang Y, Jain V, Chida N, Latypova X, Le Caignec C, Cogné B, Mercier S, Vincent M, Colin E, Bonneau D, Denommé AS, Parent P, Gilbert-Dussardier B, Odent S, Toutain A, Piton A, Dina C, Donnart A, Lindenbaum P, Charpentier E, Redon R, Iemura K, Ikeda M, Tanaka K, Bézieau S.

Hum Mutat. 2016 Apr;37(4):354-8. doi: 10.1002/humu.22952. Epub 2016 Feb 4.

41.

A Phase 2, Single Arm Study of Iniparib in Patients With BRCA1 or BRCA2 Associated Advanced Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer.

Bell-McGuinn KM, Konner JA, Tew WP, Hensley ML, Iasonos A, Charpentier E, Mironov S, Sabbatini P, Aghajanian C.

Int J Gynecol Cancer. 2016 Feb;26(2):255-60. doi: 10.1097/IGC.0000000000000591.

42.

Search for Rare Copy-Number Variants in Congenital Heart Defects Identifies Novel Candidate Genes and a Potential Role for FOXC1 in Patients With Coarctation of the Aorta.

Sanchez-Castro M, Eldjouzi H, Charpentier E, Busson PF, Hauet Q, Lindenbaum P, Delasalle-Guyomarch B, Baudry A, Pichon O, Pascal C, Lefort B, Bajolle F, Pezard P, Schott JJ, Dina C, Redon R, Gournay V, Bonnet D, Le Caignec C.

Circ Cardiovasc Genet. 2016 Feb;9(1):86-94. doi: 10.1161/CIRCGENETICS.115.001213. Epub 2015 Dec 7.

PMID:
26643481
43.

Randomized Clinical Trial of Intraosseous Methylprednisolone Injection for Acute Pulpitis Pain.

Bane K, Charpentier E, Bronnec F, Descroix V, Gaye-N'diaye F, Kane AW, Toledo R, Machtou P, Azérad J.

J Endod. 2016 Jan;42(1):2-7. doi: 10.1016/j.joen.2015.09.003. Epub 2015 Nov 18.

PMID:
26603771
44.

RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes.

Le Rhun A, Beer YY, Reimegård J, Chylinski K, Charpentier E.

RNA Biol. 2016;13(2):177-95. doi: 10.1080/15476286.2015.1110674.

45.

SOLTI NeoPARP: a phase II randomized study of two schedules of iniparib plus paclitaxel versus paclitaxel alone as neoadjuvant therapy in patients with triple-negative breast cancer.

Llombart-Cussac A, Bermejo B, Villanueva C, Delaloge S, Morales S, Balmaña J, Amillano K, Bonnefoi H, Casas A, Manso L, Roché H, Gonzalez-Santiago S, Gavilá J, Sánchez-Rovira P, Di Cosimo S, Harbeck N, Charpentier E, Garcia-Ribas I, Radosevic-Robin N, Aura C, Baselga J.

Breast Cancer Res Treat. 2015 Nov;154(2):351-7. doi: 10.1007/s10549-015-3616-8. Epub 2015 Nov 4.

46.

An updated evolutionary classification of CRISPR-Cas systems.

Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, Saunders SJ, Barrangou R, Brouns SJ, Charpentier E, Haft DH, Horvath P, Moineau S, Mojica FJ, Terns RM, Terns MP, White MF, Yakunin AF, Garrett RA, van der Oost J, Backofen R, Koonin EV.

Nat Rev Microbiol. 2015 Nov;13(11):722-36. doi: 10.1038/nrmicro3569. Epub 2015 Sep 28. Review.

47.

Fully bioresorbable drug-eluting coronary scaffolds: A review.

Charpentier E, Barna A, Guillevin L, Juliard JM.

Arch Cardiovasc Dis. 2015 Jun-Jul;108(6-7):385-97. doi: 10.1016/j.acvd.2015.03.009. Epub 2015 Jun 22. Review.

48.

Editorial: RNA in bacteria: biogenesis, regulatory mechanisms and functions.

Charpentier E, Hess WR.

FEMS Microbiol Rev. 2015 May;39(3):277-9. doi: 10.1093/femsre/fuv025. No abstract available.

49.

Toward Whole-Transcriptome Editing with CRISPR-Cas9.

Heckl D, Charpentier E.

Mol Cell. 2015 May 21;58(4):560-2. doi: 10.1016/j.molcel.2015.05.016.

50.

Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity.

Charpentier E, Richter H, van der Oost J, White MF.

FEMS Microbiol Rev. 2015 May;39(3):428-41. doi: 10.1093/femsre/fuv023. Epub 2015 May 19. Review.

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