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Items: 1 to 50 of 444

1.

New imaging tools to measure nephron number in vivo: opportunities for developmental nephrology.

Bennett KM, Baldelomar EJ, Morozov D, Chevalier RL, Charlton JR.

J Dev Orig Health Dis. 2020 Jan 27:1-5. doi: 10.1017/S204017442000001X. [Epub ahead of print]

PMID:
31983353
2.

Improved small blob detection in 3D images using jointly constrained deep learning and Hessian analysis.

Xu Y, Wu T, Gao F, Charlton JR, Bennett KM.

Sci Rep. 2020 Jan 15;10(1):326. doi: 10.1038/s41598-019-57223-y.

3.

Osteoarthritis year in review 2019: mechanics.

Hunt MA, Charlton JM, Esculier JF.

Osteoarthritis Cartilage. 2019 Dec 23. pii: S1063-4584(19)31297-X. doi: 10.1016/j.joca.2019.12.003. [Epub ahead of print] Review.

PMID:
31877382
4.

Circadian Entrainment Triggers Maturation of Human In Vitro Islets.

Alvarez-Dominguez JR, Donaghey J, Rasouli N, Kenty JHR, Helman A, Charlton J, Straubhaar JR, Meissner A, Melton DA.

Cell Stem Cell. 2020 Jan 2;26(1):108-122.e10. doi: 10.1016/j.stem.2019.11.011. Epub 2019 Dec 12.

PMID:
31839570
5.

Nephron loss detected by MRI following neonatal acute kidney injury in rabbits.

Charlton JR, Baldelomar EJ, deRonde KA, Cathro HP, Charlton NP, Criswell SJ, Hyatt DM, Nam S, Pearl V, Bennett KM.

Pediatr Res. 2019 Dec 5. doi: 10.1038/s41390-019-0684-1. [Epub ahead of print]

PMID:
31805577
6.

Incidence and Risk Factors of Early Onset Neonatal AKI.

Charlton JR, Boohaker L, Askenazi D, Brophy PD, D'Angio C, Fuloria M, Gien J, Griffin R, Hingorani S, Ingraham S, Mian A, Ohls RK, Rastogi S, Rhee CJ, Revenis M, Sarkar S, Smith A, Starr M, Kent AL; Neonatal Kidney Collaborative.

Clin J Am Soc Nephrol. 2019 Feb 7;14(2):184-195. doi: 10.2215/CJN.03670318. Epub 2019 Jan 31.

7.

Safer vehicles and technology for older adults.

Oxley J, Charlton J, Logan D, O'Hern S, Koppel S, Meuleners L.

Traffic Inj Prev. 2019 Nov 1:1-3. doi: 10.1080/15389588.2019.1661712. [Epub ahead of print]

PMID:
31674855
8.

Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.

Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, Hock H, Hochedlinger K.

Nat Cell Biol. 2019 Nov;21(11):1449-1461. doi: 10.1038/s41556-019-0403-5. Epub 2019 Oct 28.

PMID:
31659274
9.

Delayed Umbilical Cord Clamping is Not Associated with Acute Kidney Injury in Very Low Birth Weight Neonates.

Harer MW, McAdams RM, Conaway M, Vergales BD, Hyatt DM, Charlton JR.

Am J Perinatol. 2020 Jan;37(2):210-215. doi: 10.1055/s-0039-1697671. Epub 2019 Oct 13.

PMID:
31606889
10.

The development of a simulator-based intervention to rehabilitate driving skills in people with acquired brain injury.

Dimech-Betancourt B, Ross PE, Ponsford JL, Charlton JL, Stolwyk RJ.

Disabil Rehabil Assist Technol. 2019 Oct 9:1-12. doi: 10.1080/17483107.2019.1673835. [Epub ahead of print]

PMID:
31597483
11.

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.

Di Stefano B, Luo EC, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, Gerli MFM, Gu H, Gygi SP, Sadreyev RI, Meissner A, Yeo GW, Hochedlinger K.

Cell Stem Cell. 2019 Nov 7;25(5):622-638.e13. doi: 10.1016/j.stem.2019.08.018. Epub 2019 Oct 3.

PMID:
31588046
12.

The common characteristics and behaviors of child occupants in motor vehicle travel.

Cross SL, Koppel S, Arbogast KB, Bohman K, Rudin-Brown CM, Charlton JL.

Traffic Inj Prev. 2019;20(7):713-719. doi: 10.1080/15389588.2019.1654093. Epub 2019 Sep 6.

PMID:
31567027
13.

User-driven design of child restraint information to reduce errors in use: a pilot randomised controlled trial.

Hall AB, Ho C, Albanese B, Keay L, Hunter K, Charlton J, Hayen A, Bilston LE, Brown J.

Inj Prev. 2019 Sep 17. pii: injuryprev-2019-043380. doi: 10.1136/injuryprev-2019-043380. [Epub ahead of print]

PMID:
31530570
14.

Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression.

Tsankov AM, Wadsworth MH 2nd, Akopian V, Charlton J, Allon SJ, Arczewska A, Mead BE, Drake RS, Smith ZD, Mikkelsen TS, Shalek AK, Meissner A.

Development. 2019 Sep 12;146(19). pii: dev174722. doi: 10.1242/dev.174722.

PMID:
31515224
15.

In vivo measurements of kidney glomerular number and size in healthy and Os/+ mice using MRI.

Baldelomar EJ, Charlton JR, deRonde KA, Bennett KM.

Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F865-F873. doi: 10.1152/ajprenal.00078.2019. Epub 2019 Jul 24.

16.

Chronic Kidney Disease: A Life Course Health Development Perspective.

Brophy PD, Charlton JR, Bryan Carmody J, Reidy KJ, Harshman L, Segar J, Askenazi D, Shoham D, Bagby SP.

In: Halfon N, Forrest CB, Lerner RM, Faustman EM, editors. Handbook of Life Course Health Development [Internet]. Cham (CH): Springer; 2018.
2017 Nov 21.

17.

Importance of Frailty for Association of Antipsychotic Drug Use With Risk of Fracture: Cohort Study Using Electronic Health Records.

Gafoor R, Charlton J, Ravindrarajah R, Gulliford MC.

J Am Med Dir Assoc. 2019 Dec;20(12):1495-1501.e1. doi: 10.1016/j.jamda.2019.05.009. Epub 2019 Jul 1.

PMID:
31272856
18.

Individuals with knee osteoarthritis present increased gait pattern deviations as measured by a knee-specific gait deviation index.

Kobsar D, Charlton JM, Hunt MA.

Gait Posture. 2019 Jul;72:82-88. doi: 10.1016/j.gaitpost.2019.05.020. Epub 2019 May 29.

PMID:
31173950
19.

Validity and reliability of a shoe-embedded sensor module for measuring foot progression angle during over-ground walking.

Charlton JM, Xia H, Shull PB, Hunt MA.

J Biomech. 2019 May 24;89:123-127. doi: 10.1016/j.jbiomech.2019.04.012. Epub 2019 Apr 17.

PMID:
31047695
20.

Electronically delivered interventions to reduce antibiotic prescribing for respiratory infections in primary care: cluster RCT using electronic health records and cohort study.

Gulliford MC, Juszczyk D, Prevost AT, Soames J, McDermott L, Sultana K, Wright M, Fox R, Hay AD, Little P, Moore M, Yardley L, Ashworth M, Charlton J.

Health Technol Assess. 2019 Mar;23(11):1-70. doi: 10.3310/hta23110.

21.

Phase I study of orally administered 14Carbon-isotope labelled-vistusertib (AZD2014), a dual TORC1/2 kinase inhibitor, to assess the absorption, metabolism, excretion, and pharmacokinetics in patients with advanced solid malignancies.

MacDonald A, Scarfe G, Magirr D, Sarvotham T, Charlton J, Brugger W, Dean E.

Cancer Chemother Pharmacol. 2019 Apr;83(4):787-795. doi: 10.1007/s00280-019-03781-x. Epub 2019 Feb 13.

PMID:
30758651
22.

Effectiveness and safety of electronically delivered prescribing feedback and decision support on antibiotic use for respiratory illness in primary care: REDUCE cluster randomised trial.

Gulliford MC, Prevost AT, Charlton J, Juszczyk D, Soames J, McDermott L, Sultana K, Wright M, Fox R, Hay AD, Little P, Moore MV, Yardley L, Ashworth M.

BMJ. 2019 Feb 12;364:l236. doi: 10.1136/bmj.l236.

23.

Immature megalin expression in the preterm neonatal kidney is associated with urinary loss of vitamin carrier proteins.

Charlton JR, Harer MW, Swan C, Nielsen R.

Pediatr Res. 2019 Feb;85(3):405-411. doi: 10.1038/s41390-018-0261-z. Epub 2018 Dec 20.

PMID:
30659269
24.

A systematic review of the risk of motor vehicle collision after stroke or transient ischemic attack.

Rapoport MJ, Plonka SC, Finestone H, Bayley M, Chee JN, Vrkljan B, Koppel S, Linkewich E, Charlton JL, Marshall S, delCampo M, Boulos MI, Swartz RH, Bhangu J, Saposnik G, Comay J, Dow J, Ayotte D, O'Neill D.

Top Stroke Rehabil. 2019 Apr;26(3):226-235. doi: 10.1080/10749357.2018.1558634. Epub 2019 Jan 5.

PMID:
30614401
25.

Late onset neonatal acute kidney injury: results from the AWAKEN Study.

Charlton JR, Boohaker L, Askenazi D, Brophy PD, Fuloria M, Gien J, Griffin R, Hingorani S, Ingraham S, Mian A, Ohls RK, Rastogi S, Rhee CJ, Revenis M, Sarkar S, Starr M, Kent AL; Neonatal Kidney Collaborative (NKC).

Pediatr Res. 2019 Feb;85(3):339-348. doi: 10.1038/s41390-018-0255-x. Epub 2018 Dec 13.

26.

Self-reported violations, errors and lapses for older drivers: Measuring the change in frequency of aberrant driving behaviours across five time-points.

Koppel S, Stephens AN, Bédard M, Charlton JL, Darzins P, Stefano MD, Gagnon S, Gélinas I, Hua P, MacLeay L, Man-Son-Hing M, Mazer B, Myers A, Naglie G, Odell M, Porter MM, Rapoport MJ, Stinchcombe A, Tuokko H, Vrkjlan B, Marshall S.

Accid Anal Prev. 2019 Feb;123:132-139. doi: 10.1016/j.aap.2018.11.009. Epub 2018 Nov 24.

PMID:
30481684
27.

Targets and genomic constraints of ectopic Dnmt3b expression.

Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A.

Elife. 2018 Nov 23;7. pii: e40757. doi: 10.7554/eLife.40757.

28.

Ankle Joint and Rearfoot Biomechanics During Toe-In and Toe-Out Walking in People With Medial Compartment Knee Osteoarthritis.

Charlton JM, Hatfield GL, Guenette JA, Hunt MA.

PM R. 2019 May;11(5):503-511. doi: 10.1016/j.pmrj.2018.08.388. Epub 2019 Apr 1.

PMID:
30195708
29.

Risk of Motor Vehicle Collision or Driving Impairment After Traumatic Brain Injury: A Collaborative International Systematic Review and Meta-Analysis.

Chee JN, Hawley C, Charlton JL, Marshall S, Gillespie I, Koppel S, Vrkljan B, Ayotte D, Rapoport MJ.

J Head Trauma Rehabil. 2019 Jan/Feb;34(1):E27-E38. doi: 10.1097/HTR.0000000000000400.

PMID:
30045219
30.

Surface Modification of Silicon Pillar Arrays To Enhance Fluorescence Detection of Uranium and DNA.

Lincoln DR, Charlton JJ, Hatab NA, Skyberg B, Lavrik NV, Kravchenko II, Bradshaw JA, Sepaniak MJ.

ACS Omega. 2017 Oct 31;2(10):7313-7319. doi: 10.1021/acsomega.7b00912. Epub 2017 Oct 27.

31.

Is quality of life reduced in people with patellofemoral osteoarthritis and does it improve with treatment? A systematic review, meta-analysis and regression.

Hart HF, Filbay SR, Coburn S, Charlton JM, Sritharan P, Crossley KM.

Disabil Rehabil. 2018 Jul 10:1-15. doi: 10.1080/09638288.2018.1482504. [Epub ahead of print]

PMID:
29987962
32.

Hybrid Organic-Inorganic Rotaxanes, Including a Hetero-Hybrid [3]Rotaxane Featuring Two Distinct Heterometallic Rings and a Molecular Shuttle.

Timco GA, Fernandez A, Kostopoulos AK, Charlton JF, Lockyer SJ, Hailes TR, Adams RW, McInnes EJL, Tuna F, Vitorica-Yrezabal IJ, Whitehead GFS, Winpenny REP.

Angew Chem Int Ed Engl. 2018 Aug 20;57(34):10919-10922. doi: 10.1002/anie.201805439. Epub 2018 Jul 18.

PMID:
29932482
33.

Toe-in and toe-out walking require different lower limb neuromuscular patterns in people with knee osteoarthritis.

Charlton JM, Hatfield GL, Guenette JA, Hunt MA.

J Biomech. 2018 Jul 25;76:112-118. doi: 10.1016/j.jbiomech.2018.05.041. Epub 2018 Jun 18.

PMID:
29914739
34.

Using Naturalistic Methods to Examine Real-World Driving Behavior in Individuals With TBI Upon Return to Driving: A Pilot Study.

Hua P, Charlton JL, Ponsford JL, Gooden JR, Ross PE, Bédard M, Marshall S, Gagnon S, Stolwyk RJ.

J Head Trauma Rehabil. 2019 Jan/Feb;34(1):E55-E60. doi: 10.1097/HTR.0000000000000410.

PMID:
29863623
35.

An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles.

Hall SCL, Tognoloni C, Charlton J, Bragginton ÉC, Rothnie AJ, Sridhar P, Wheatley M, Knowles TJ, Arnold T, Edler KJ, Dafforn TR.

Nanoscale. 2018 Jun 7;10(22):10609-10619. doi: 10.1039/c8nr01322e.

36.

Clinical and biomechanical changes following a 4-month toe-out gait modification program for people with medial knee osteoarthritis: a randomized controlled trial.

Hunt MA, Charlton JM, Krowchuk NM, Tse CTF, Hatfield GL.

Osteoarthritis Cartilage. 2018 Jul;26(7):903-911. doi: 10.1016/j.joca.2018.04.010. Epub 2018 Apr 27.

37.

Association Between Early Caffeine Citrate Administration and Risk of Acute Kidney Injury in Preterm Neonates: Results From the AWAKEN Study.

Harer MW, Askenazi DJ, Boohaker LJ, Carmody JB, Griffin RL, Guillet R, Selewski DT, Swanson JR, Charlton JR; Neonatal Kidney Collaborative (NKC).

JAMA Pediatr. 2018 Jun 4;172(6):e180322. doi: 10.1001/jamapediatrics.2018.0322. Epub 2018 Jun 4. Erratum in: JAMA Pediatr. 2018 Jun 1;172(6):599.

38.

Long-term trends in antithrombotic drug prescriptions among adults aged 80 years and over from primary care: a temporal trends analysis using electronic health records.

Dregan A, Ravindrarajah R, Charlton J, Ashworth M, Molokhia M.

Ann Epidemiol. 2018 Jul;28(7):440-446. doi: 10.1016/j.annepidem.2018.03.006. Epub 2018 Mar 19.

PMID:
29609872
39.

Calcium/calmodulin-stimulated adenylyl cyclases 1 and 8 regulate reward-related brain activity and ethanol consumption.

Bosse KE, Ghoddoussi F, Eapen AT, Charlton JL, Susick LL, Desai K, Berkowitz BA, Perrine SA, Conti AC.

Brain Imaging Behav. 2019 Apr;13(2):396-407. doi: 10.1007/s11682-018-9856-6.

40.

Understanding fatal older road user crash circumstances and risk factors.

Koppel S, Bugeja L, Smith D, Lamb A, Dwyer J, Fitzharris M, Newstead S, D'Elia A, Charlton J.

Traffic Inj Prev. 2018 Feb 28;19(sup1):S181-S183. doi: 10.1080/15389588.2018.1426911.

PMID:
29584508
41.

Frontal and oblique crash tests of HIII 6-year-old child ATD using real-world, observed child passenger postures.

Bohman K, Arbogast KB, Loeb H, Charlton JL, Koppel S, Cross SL.

Traffic Inj Prev. 2018 Feb 28;19(sup1):S125-S130. doi: 10.1080/15389588.2017.1385781.

PMID:
29584494
42.

Author Correction: Global delay in nascent strand DNA methylation.

Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A.

Nat Struct Mol Biol. 2018 Apr;25(4):355. doi: 10.1038/s41594-018-0055-3.

PMID:
29581568
43.

Contralateral limb foot rotation during unilateral toe-in or toe-out walking in people with knee osteoarthritis.

Charlton JM, Krowchuk NM, Hatfield GL, Guenette JA, Hunt MA.

Gait Posture. 2018 May;62:132-134. doi: 10.1016/j.gaitpost.2018.03.013. Epub 2018 Mar 6.

PMID:
29547793
44.

Global delay in nascent strand DNA methylation.

Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A.

Nat Struct Mol Biol. 2018 Apr;25(4):327-332. doi: 10.1038/s41594-018-0046-4. Epub 2018 Mar 12. Erratum in: Nat Struct Mol Biol. 2018 Mar 26;:.

45.

Can child restraint product information developed using consumer testing sustain correct use 6 months after child restraint purchase? Study protocol for a cluster randomised controlled trial.

Brown J, Elkington J, Hall A, Keay L, Charlton JL, Hunter K, Koppel S, Hayen A, Bilston LE.

Inj Prev. 2019 Jun;25(3):175-179. doi: 10.1136/injuryprev-2017-042571. Epub 2018 Mar 7.

PMID:
29514847
46.

Genome-wide tracking of dCas9-methyltransferase footprints.

Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Schöler HR, Gnirke A, Ziller MJ, Meissner A.

Nat Commun. 2018 Feb 9;9(1):597. doi: 10.1038/s41467-017-02708-5.

47.

The Driver Behaviour Questionnaire for older drivers: Do errors, violations and lapses change over time?

Koppel S, Stephens AN, Charlton JL, Di Stefano M, Darzins P, Odell M, Marshall S.

Accid Anal Prev. 2018 Apr;113:171-178. doi: 10.1016/j.aap.2018.01.036. Epub 2018 Mar 7.

PMID:
29407664
48.

Is acute kidney injury a harbinger for chronic kidney disease?

Selewski DT, Hyatt DM, Bennett KM, Charlton JR.

Curr Opin Pediatr. 2018 Apr;30(2):236-240. doi: 10.1097/MOP.0000000000000587. Review.

49.

Genetic determinants and epigenetic effects of pioneer-factor occupancy.

Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A.

Nat Genet. 2018 Feb;50(2):250-258. doi: 10.1038/s41588-017-0034-3. Epub 2018 Jan 22.

50.

Incidence and mortality of fractures by frailty level over 80 years of age: cohort study using UK electronic health records.

Ravindrarajah R, Hazra NC, Charlton J, Jackson SHD, Dregan A, Gulliford MC.

BMJ Open. 2018 Jan 21;8(1):e018836. doi: 10.1136/bmjopen-2017-018836.

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