Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 40

1.

Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.

Nokin MJ, Bellier J, Durieux F, Peulen O, Rademaker G, Gabriel M, Monseur C, Charloteaux B, Verbeke L, van Laere S, Roncarati P, Herfs M, Lambert C, Scheijen J, Schalkwijk C, Colige A, Caers J, Delvenne P, Turtoi A, Castronovo V, Bellahcène A.

Breast Cancer Res. 2019 Jan 23;21(1):11. doi: 10.1186/s13058-018-1095-7.

2.

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.

Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, Pierik MJ, Vander Meulen-de Jong AE, Janneke van der Woude C, Visschedijk MC; International IBD Genetics Consortium, Lathrop M, Hugot JP, Weersma RK, De Vos M, Franchimont D, Vermeire S, Kubo M, Louis E, Georges M.

Nat Commun. 2018 Jun 21;9(1):2427. doi: 10.1038/s41467-018-04365-8.

3.

Codon-specific translation reprogramming promotes resistance to targeted therapy.

Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, De Tullio P, Sin O, Shostak K, Schmitz S, Piepers J, Ghesquière B, Karim L, Charloteaux B, Jamart D, Florin A, Lambert C, Rorive A, Jerusalem G, Leucci E, Dewaele M, Vooijs M, Leidel SA, Georges M, Voz M, Peers B, Büttner R, Marine JC, Chariot A, Close P.

Nature. 2018 Jun;558(7711):605-609. doi: 10.1038/s41586-018-0243-7. Epub 2018 Jun 20.

PMID:
29925953
4.

Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's Disease.

Amininejad L, Charloteaux B, Theatre E, Liefferinckx C, Dmitrieva J, Hayard P, Muls V, Maisin JM, Schapira M, Ghislain JM, Closset P, Talib M, Abramowicz M, Momozawa Y, Deffontaine V, Crins F, Mni M, Karim L, Cambisano N, Ornemese S, Zucchi A, Minsart C, Deviere J, Hugot JP, De Vos M, Louis E, Vermeire S, Van Gossum A, Coppieters W, Twizere JC, Georges M, Franchimont D; International IBD Genetics Consortium.

Gastroenterology. 2018 Jun;154(8):2165-2177. doi: 10.1053/j.gastro.2018.02.028. Epub 2018 Mar 6.

PMID:
29501442
5.

Transcriptome-wide analysis of natural antisense transcripts shows their potential role in breast cancer.

Wenric S, ElGuendi S, Caberg JH, Bezzaou W, Fasquelle C, Charloteaux B, Karim L, Hennuy B, Frères P, Collignon J, Boukerroucha M, Schroeder H, Olivier F, Jossa V, Jerusalem G, Josse C, Bours V.

Sci Rep. 2017 Dec 12;7(1):17452. doi: 10.1038/s41598-017-17811-2.

6.

An inter-species protein-protein interaction network across vast evolutionary distance.

Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M.

Mol Syst Biol. 2016 Apr 22;12(4):865. doi: 10.15252/msb.20156484.

7.

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M.

Cell. 2016 Feb 11;164(4):805-17. doi: 10.1016/j.cell.2016.01.029.

8.

Widespread macromolecular interaction perturbations in human genetic disorders.

Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabási AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M.

Cell. 2015 Apr 23;161(3):647-660. doi: 10.1016/j.cell.2015.04.013.

9.

A proteome-scale map of the human interactome network.

Rolland T, Taşan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C, Franzosa E, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Trigg SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabási AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA, Hill DE, Hao T, Roth FP, Vidal M.

Cell. 2014 Nov 20;159(5):1212-1226. doi: 10.1016/j.cell.2014.10.050.

10.

Edgotype: a fundamental link between genotype and phenotype.

Sahni N, Yi S, Zhong Q, Jailkhani N, Charloteaux B, Cusick ME, Vidal M.

Curr Opin Genet Dev. 2013 Dec;23(6):649-57. doi: 10.1016/j.gde.2013.11.002. Epub 2013 Nov 26. Review.

11.

An efficient algorithm to perform multiple testing in epistasis screening.

Van Lishout F, Mahachie John JM, Gusareva ES, Urrea V, Cleynen I, Théâtre E, Charloteaux B, Calle ML, Wehenkel L, Van Steen K.

BMC Bioinformatics. 2013 Apr 24;14:138. doi: 10.1186/1471-2105-14-138.

12.

Proto-genes and de novo gene birth.

Carvunis AR, Rolland T, Wapinski I, Calderwood MA, Yildirim MA, Simonis N, Charloteaux B, Hidalgo CA, Barbette J, Santhanam B, Brar GA, Weissman JS, Regev A, Thierry-Mieg N, Cusick ME, Vidal M.

Nature. 2012 Jul 19;487(7407):370-4. doi: 10.1038/nature11184.

13.

Protein-protein interactions and networks: forward and reverse edgetics.

Charloteaux B, Zhong Q, Dreze M, Cusick ME, Hill DE, Vidal M.

Methods Mol Biol. 2011;759:197-213. doi: 10.1007/978-1-61779-173-4_12.

PMID:
21863489
14.

Edgetic perturbation models of human inherited disorders.

Zhong Q, Simonis N, Li QR, Charloteaux B, Heuze F, Klitgord N, Tam S, Yu H, Venkatesan K, Mou D, Swearingen V, Yildirim MA, Yan H, Dricot A, Szeto D, Lin C, Hao T, Fan C, Milstein S, Dupuy D, Brasseur R, Hill DE, Cusick ME, Vidal M.

Mol Syst Biol. 2009;5:321. doi: 10.1038/msb.2009.80. Epub 2009 Nov 3.

15.

'Edgetic' perturbation of a C. elegans BCL2 ortholog.

Dreze M, Charloteaux B, Milstein S, Vidalain PO, Yildirim MA, Zhong Q, Svrzikapa N, Romero V, Laloux G, Brasseur R, Vandenhaute J, Boxem M, Cusick ME, Hill DE, Vidal M.

Nat Methods. 2009 Nov;6(11):843-9. doi: 10.1038/nmeth.1394. Epub 2009 Oct 25. Erratum in: Nat Methods. 2009 Dec;6(12):935.

16.

Structural features conferring dual geranyl/farnesyl diphosphate synthase activity to an aphid prenyltransferase.

Vandermoten S, Santini S, Haubruge E, Heuze F, Francis F, Brasseur R, Cusson M, Charloteaux B.

Insect Biochem Mol Biol. 2009 Oct;39(10):707-16. doi: 10.1016/j.ibmb.2009.08.007. Epub 2009 Aug 29.

17.

The "Tilted Peptide Theory" links membrane insertion properties and fusogenicity of viral fusion peptides.

Charloteaux B, Lorin A, Brasseur R, Lins L.

Protein Pept Lett. 2009;16(7):718-25. Review.

PMID:
19601900
18.

Study of Thermomyces lanuginosa lipase in the presence of tributyrylglycerol and water.

Santini S, Crowet JM, Thomas A, Paquot M, Vandenbol M, Thonart P, Wathelet JP, Blecker C, Lognay G, Brasseur R, Lins L, Charloteaux B.

Biophys J. 2009 Jun 17;96(12):4814-25. doi: 10.1016/j.bpj.2009.03.040.

19.

PepLook: an innovative in silico tool for determination of structure, polymorphism and stability of peptides.

Thomas A, Deshayes S, Decaffmeyer M, Van Eyck MH, Charloteaux BB, Brasseur R.

Adv Exp Med Biol. 2009;611:459-60. No abstract available.

PMID:
19400265
20.

Determination of the minimal fusion peptide of HIV, SIV and BLV fusion glycoproteins.

Lorin A, Charloteaux B, Lins L, Stroobant V, Brasseur R.

Adv Exp Med Biol. 2009;611:387-8. No abstract available.

PMID:
19400236
21.

Genomic location of the bovine growth hormone secretagogue receptor (GHSR) gene and investigation of genetic polymorphism.

Colinet FG, Vanderick S, Charloteaux B, Eggen A, Gengler N, Renaville B, Brasseur R, Portetelle D, Renaville R.

Anim Biotechnol. 2009;20(1):28-33. doi: 10.1080/10495390802602926.

22.

Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity.

Vandermoten S, Charloteaux B, Santini S, Sen SE, Béliveau C, Vandenbol M, Francis F, Brasseur R, Cusson M, Haubruge E.

FEBS Lett. 2008 Jun 11;582(13):1928-34. doi: 10.1016/j.febslet.2008.04.043. Epub 2008 May 6. Erratum in: FEBS Lett. 2008 Jul 9;582(16):2471.

23.

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling.

Adam B, Charloteaux B, Beaufays J, Vanhamme L, Godfroid E, Brasseur R, Lins L.

BMC Struct Biol. 2008 Jan 11;8:1. doi: 10.1186/1472-6807-8-1.

24.

Variability and action mechanism of a family of anticomplement proteins in Ixodes ricinus.

Couvreur B, Beaufays J, Charon C, Lahaye K, Gensale F, Denis V, Charloteaux B, Decrem Y, Prévôt PP, Brossard M, Vanhamme L, Godfroid E.

PLoS One. 2008 Jan 2;3(1):e1400. doi: 10.1371/journal.pone.0001400.

25.

The minimal fusion peptide of simian immunodeficiency virus corresponds to the 11 first residues of gp32.

Lorin A, Lins L, Stroobant V, Brasseur R, Charloteaux B.

J Pept Sci. 2008 Apr;14(4):423-8.

PMID:
17994611
26.

Lipid-destabilizing properties of the hydrophobic helices H8 and H9 from colicin E1.

Lins L, El Kirat K, Charloteaux B, Flore C, Stroobant V, Thomas A, Dufrene Y, Brasseur R.

Mol Membr Biol. 2007 Sep-Dec;24(5-6):419-30.

PMID:
17710646
27.

Tilted properties of the 67-78 fragment of alpha-synuclein are responsible for membrane destabilization and neurotoxicity.

Crowet JM, Lins L, Dupiereux I, Elmoualija B, Lorin A, Charloteaux B, Stroobant V, Heinen E, Brasseur R.

Proteins. 2007 Sep 1;68(4):936-47.

28.

Mode of membrane interaction and fusogenic properties of a de novo transmembrane model peptide depend on the length of the hydrophobic core.

Lorin A, Charloteaux B, Fridmann-Sirkis Y, Thomas A, Shai Y, Brasseur R.

J Biol Chem. 2007 Jun 22;282(25):18388-96. Epub 2007 Apr 24.

29.

Determination of the minimal fusion peptide of bovine leukemia virus gp30.

Lorin A, Lins L, Stroobant V, Brasseur R, Charloteaux B.

Biochem Biophys Res Commun. 2007 Apr 13;355(3):649-53. Epub 2007 Feb 8.

PMID:
17307138
30.

Prediction of peptide structure: how far are we?

Thomas A, Deshayes S, Decaffmeyer M, Van Eyck MH, Charloteaux B, Brasseur R.

Proteins. 2006 Dec 1;65(4):889-97.

PMID:
17019719
31.

The N-terminal 12 residue long peptide of HIV gp41 is the minimal peptide sufficient to induce significant T-cell-like membrane destabilization in vitro.

Charloteaux B, Lorin A, Crowet JM, Stroobant V, Lins L, Thomas A, Brasseur R.

J Mol Biol. 2006 Jun 9;359(3):597-609. Epub 2006 Apr 25.

PMID:
16677669
32.

Rational design of complementary peptides to the betaAmyloid 29-42 fusion peptide: an application of PepDesign.

Decaffmeyer M, Lins L, Charloteaux B, VanEyck MH, Thomas A, Brasseur R.

Biochim Biophys Acta. 2006 Mar;1758(3):320-7. Epub 2005 Oct 25.

33.

"De novo" design of peptides with specific lipid-binding properties.

Lins L, Charloteaux B, Heinen C, Thomas A, Brasseur R.

Biophys J. 2006 Jan 15;90(2):470-9. Epub 2005 Nov 4.

34.

Protein-nucleic acid recognition: statistical analysis of atomic interactions and influence of DNA structure.

Lejeune D, Delsaux N, Charloteaux B, Thomas A, Brasseur R.

Proteins. 2005 Nov 1;61(2):258-71.

PMID:
16121397
35.

HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment. Characterization of gp41 mutants.

Krell T, Greco F, Engel O, Dubayle J, Dubayle J, Kennel A, Charloteaux B, Brasseur R, Chevalier M, Sodoyer R, El Habib R.

Eur J Biochem. 2004 Apr;271(8):1566-79.

36.

Aromatic side-chain interactions in proteins. I. Main structural features.

Thomas A, Meurisse R, Charloteaux B, Brasseur R.

Proteins. 2002 Sep 1;48(4):628-34.

PMID:
12211030
37.
38.

Prediction of membrane protein orientation in lipid bilayers: a theoretical approach.

Basyn F, Charloteaux B, Thomas A, Brasseur R.

J Mol Graph Model. 2001;20(3):235-44.

PMID:
11766048
39.

Computational study of lipid-destabilizing protein fragments: towards a comprehensive view of tilted peptides.

Lins L, Charloteaux B, Thomas A, Brasseur R.

Proteins. 2001 Sep 1;44(4):435-47.

PMID:
11484221
40.

A fast method to predict protein interaction sites from sequences.

Gallet X, Charloteaux B, Thomas A, Brasseur R.

J Mol Biol. 2000 Sep 29;302(4):917-26.

PMID:
10993732

Supplemental Content

Loading ...
Support Center