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Items: 24

1.

Validation of a Muscle-Specific Tissue Image-Analysis Tool for Quantitative Assessment of Dystrophin Staining in Frozen Muscle Biopsies.

Aeffner F, Faelan C, Moore SA, Moody A, Black JC, Charleston JS, Frank DE, Dworzak J, Piper JK, Ranjitkar M, Wilson K, Kanaly S, Rudmann DG, Lange H, Young GD, Milici AJ.

Arch Pathol Lab Med. 2018 Aug 31. doi: 10.5858/arpa.2017-0536-OA. [Epub ahead of print]

PMID:
30168727
2.

Eteplirsen treatment for Duchenne muscular dystrophy: Exon skipping and dystrophin production.

Charleston JS, Schnell FJ, Dworzak J, Donoghue C, Lewis S, Chen L, Young GD, Milici AJ, Voss J, DeAlwis U, Wentworth B, Rodino-Klapac LR, Sahenk Z, Frank D, Mendell JR.

Neurology. 2018 Jun 12;90(24):e2146-e2154. doi: 10.1212/WNL.0000000000005680. Epub 2018 May 11. Erratum in: Neurology. 2018 Sep 25;91(13):637.

PMID:
29752304
3.

Toxicological Characterization of Exon Skipping Phosphorodiamidate Morpholino Oligomers (PMOs) in Non-human Primates.

Carver MP, Charleston JS, Shanks C, Zhang J, Mense M, Sharma AK, Kaur H, Sazani P.

J Neuromuscul Dis. 2016 Aug 30;3(3):381-393.

PMID:
27854228
4.

Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques.

Warren TK, Whitehouse CA, Wells J, Welch L, Charleston JS, Heald A, Nichols DK, Mattix ME, Palacios G, Kugleman JR, Iversen PL, Bavari S.

PLoS Negl Trop Dis. 2016 Feb 22;10(2):e0004456. doi: 10.1371/journal.pntd.0004456. eCollection 2016 Feb.

5.

AVI-7288 for Marburg Virus in Nonhuman Primates and Humans.

Heald AE, Charleston JS, Iversen PL, Warren TK, Saoud JB, Al-Ibrahim M, Wells J, Warfield KL, Swenson DL, Welch LS, Sazani P, Wong M, Berry D, Kaye EM, Bavari S.

N Engl J Med. 2015 Jul 23;373(4):339-48. doi: 10.1056/NEJMoa1410345.

6.

A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection.

Warren TK, Whitehouse CA, Wells J, Welch L, Heald AE, Charleston JS, Sazani P, Reid SP, Iversen PL, Bavari S.

MBio. 2015 Feb 10;6(1). pii: e02344-14. doi: 10.1128/mBio.02344-14.

7.

Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against ebola virus and marburg virus: results of two single-ascending-dose studies.

Heald AE, Iversen PL, Saoud JB, Sazani P, Charleston JS, Axtelle T, Wong M, Smith WB, Vutikullird A, Kaye E.

Antimicrob Agents Chemother. 2014 Nov;58(11):6639-47. doi: 10.1128/AAC.03442-14. Epub 2014 Aug 25.

8.

Effects of environmental enrichment on the amyotrophic lateral sclerosis mouse model.

Sorrells AD, Corcoran-Gomez K, Eckert KA, Fahey AG, Hoots BL, Charleston LB, Charleston JS, Roberts CR, Markowitz H.

Lab Anim. 2009 Apr;43(2):182-90. doi: 10.1258/la.2008.005090. Epub 2009 Feb 26.

PMID:
19246505
9.

A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause.

Hansen KR, Knowlton NS, Thyer AC, Charleston JS, Soules MR, Klein NA.

Hum Reprod. 2008 Mar;23(3):699-708. doi: 10.1093/humrep/dem408. Epub 2008 Jan 11.

PMID:
18192670
10.

Compensatory paracrine mechanisms that define the urothelial response to injury in partial bladder outlet obstruction.

Lendvay TS, Sweet R, Han CH, Soygur T, Cheng JF, Plaire JC, Charleston JS, Charleston LB, Bagai S, Cochrane K, Rubio E, Bassuk JA.

Am J Physiol Renal Physiol. 2007 Oct;293(4):F1147-56. Epub 2007 Jul 3.

11.

Estimating human ovarian non-growing follicle number: the application of modern stereology techniques to an old problem.

Charleston JS, Hansen KR, Thyer AC, Charleston LB, Gougeon A, Siebert JR, Soules MR, Klein NA.

Hum Reprod. 2007 Aug;22(8):2103-10. Epub 2007 Jun 4.

PMID:
17548367
12.

Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development.

Díaz D, Krejsa CM, White CC, Charleston JS, Kavanagh TJ.

Reprod Toxicol. 2004 Nov;19(1):117-29.

PMID:
15336720
13.

Neuronal and glial cell number in the hippocampus after experimental traumatic brain injury: analysis by stereological estimation.

Grady MS, Charleston JS, Maris D, Witgen BM, Lifshitz J.

J Neurotrauma. 2003 Oct;20(10):929-41.

PMID:
14588110
14.

Effect of methylmercury on midbrain cell proliferation during organogenesis: potential cross-species differences and implications for risk assessment.

Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM.

Toxicol Sci. 2003 Sep;75(1):124-33. Epub 2003 Jun 12.

PMID:
12805652
15.

Changes in cell cycle parameters and cell number in the rat midbrain during organogenesis.

Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM.

Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):117-28.

PMID:
12644255
16.

Estimating cell number in the central nervous system by stereological methods: the optical disector and fractionator.

Charleston JS.

Curr Protoc Toxicol. 2001;Chapter 12:Unit12.6. doi: 10.1002/0471140856.tx1206s06.

PMID:
23045035
17.

Morphometric analysis of primordial follicle number in pigtailed monkey ovaries: symmetry and relationship with age.

Miller PB, Charleston JS, Battaglia DE, Klein NA, Soules MR.

Biol Reprod. 1999 Aug;61(2):553-6.

PMID:
10411540
18.

An accurate, simple method for unbiased determination of primordial follicle number in the primate ovary.

Miller PB, Charleston JS, Battaglia DE, Klein NA, Soules MR.

Biol Reprod. 1997 Apr;56(4):909-15.

PMID:
9096872
19.

Metabolism of methylmercury in the brain and its toxicological significance.

Mottet NK, Vahter ME, Charleston JS, Friberg LT.

Met Ions Biol Syst. 1997;34:371-403. Review. No abstract available.

PMID:
9046576
20.

Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure.

Charleston JS, Body RL, Bolender RP, Mottet NK, Vahter ME, Burbacher TM.

Neurotoxicology. 1996 Spring;17(1):127-38.

PMID:
8784824
21.

Demethylation of methyl mercury in different brain sites of Macaca fascicularis monkeys during long-term subclinical methyl mercury exposure.

Vahter ME, Mottet NK, Friberg LT, Lind SB, Charleston JS, Burbacher TM.

Toxicol Appl Pharmacol. 1995 Oct;134(2):273-84.

PMID:
7570604
23.

Increases in the number of reactive glia in the visual cortex of Macaca fascicularis following subclinical long-term methyl mercury exposure.

Charleston JS, Bolender RP, Mottet NK, Body RL, Vahter ME, Burbacher TM.

Toxicol Appl Pharmacol. 1994 Dec;129(2):196-206.

PMID:
7992310
24.

Software for counting cells and estimating structural volumes with the optical disector and fractionator.

Bolender RP, Charleston JS.

Microsc Res Tech. 1993 Jul 1;25(4):314-24.

PMID:
8358082

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