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Items: 1 to 50 of 122

1.

The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.

Ren J, Nettleship JE, Harris G, Mwangi W, Rhaman N, Grant C, Kotecha A, Fry E, Charleston B, Stuart DI, Hammond J, Owens RJ.

Mol Immunol. 2019 May 14;112:123-130. doi: 10.1016/j.molimm.2019.04.026. [Epub ahead of print]

2.

Persistent Infection of African Buffalo (Syncerus caffer) with Foot-and-Mouth Disease Virus: Limited Viral Evolution and No Evidence of Antibody Neutralization Escape.

Cortey M, Ferretti L, Pérez-Martín E, Zhang F, de Klerk-Lorist LM, Scott K, Freimanis G, Seago J, Ribeca P, van Schalkwyk L, Juleff ND, Maree FF, Charleston B.

J Virol. 2019 Jul 17;93(15). pii: e00563-19. doi: 10.1128/JVI.00563-19. Print 2019 Aug 1.

PMID:
31092573
3.

Vaccine-mediated protection of pigs against infection with pandemic H1N1 2009 swine influenza A virus requires a close antigenic match between the vaccine antigen and challenge virus.

Everett HE, Aramouni M, Coward V, Ramsay A, Kelly M, Morgan S, Tchilian E, Canini L, Woolhouse MEJ, Gilbert S, Charleston B, Brown IH, Brookes SM.

Vaccine. 2019 Apr 17;37(17):2288-2293. doi: 10.1016/j.vaccine.2019.02.078. Epub 2019 Mar 23.

4.

Chimeric O1K foot-and-mouth disease virus with SAT2 outer capsid as an FMD vaccine candidate.

Kotecha A, Perez-Martin E, Harvey Y, Zhang F, Ilca SL, Fry EE, Jackson B, Maree F, Scott K, Hecksel CW, Harmsen MM, Mioulet V, Wood B, Juleff N, Stuart DI, Charleston B, Seago J.

Sci Rep. 2018 Sep 12;8(1):13654. doi: 10.1038/s41598-018-31856-x.

5.

Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig.

Tungatt K, Dolton G, Morgan SB, Attaf M, Fuller A, Whalley T, Hemmink JD, Porter E, Szomolay B, Montoya M, Hammond JA, Miles JJ, Cole DK, Townsend A, Bailey M, Rizkallah PJ, Charleston B, Tchilian E, Sewell AK.

PLoS Pathog. 2018 May 17;14(5):e1007017. doi: 10.1371/journal.ppat.1007017. eCollection 2018 May.

6.

Therapeutic Administration of Broadly Neutralizing FI6 Antibody Reveals Lack of Interaction Between Human IgG1 and Pig Fc Receptors.

Morgan SB, Holzer B, Hemmink JD, Salguero FJ, Schwartz JC, Agatic G, Cameroni E, Guarino B, Porter E, Rijal P, Townsend A, Charleston B, Corti D, Tchilian E.

Front Immunol. 2018 Apr 24;9:865. doi: 10.3389/fimmu.2018.00865. eCollection 2018.

7.

Comparison of Heterosubtypic Protection in Ferrets and Pigs Induced by a Single-Cycle Influenza Vaccine.

Holzer B, Morgan SB, Matsuoka Y, Edmans M, Salguero FJ, Everett H, Brookes SM, Porter E, MacLoughlin R, Charleston B, Subbarao K, Townsend A, Tchilian E.

J Immunol. 2018 Jun 15;200(12):4068-4077. doi: 10.4049/jimmunol.1800142. Epub 2018 Apr 27.

8.

The major histocompatibility complex homozygous inbred Babraham pig as a resource for veterinary and translational medicine.

Schwartz JC, Hemmink JD, Graham SP, Tchilian E, Charleston B, Hammer SE, Ho CS, Hammond JA.

HLA. 2018 Apr 23. doi: 10.1111/tan.13281. [Epub ahead of print]

9.

Recent advances in veterinary applications of structural vaccinology.

Charleston B, Graham SP.

Curr Opin Virol. 2018 Apr;29:33-38. doi: 10.1016/j.coviro.2018.02.006. Epub 2018 Mar 16. Review.

10.

Detection of Pathogen Exposure in African Buffalo Using Non-Specific Markers of Inflammation.

Glidden CK, Beechler B, Buss PE, Charleston B, de Klerk-Lorist LM, Maree FF, Muller T, Pérez-Martin E, Scott KA, van Schalkwyk OL, Jolles A.

Front Immunol. 2018 Jan 11;8:1944. doi: 10.3389/fimmu.2017.01944. eCollection 2017.

11.

Isolation of Single-Domain Antibody Fragments That Preferentially Detect Intact (146S) Particles of Foot-and-Mouth Disease Virus for Use in Vaccine Quality Control.

Harmsen MM, Seago J, Perez E, Charleston B, Eblé PL, Dekker A.

Front Immunol. 2017 Aug 17;8:960. doi: 10.3389/fimmu.2017.00960. eCollection 2017.

12.

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus.

Kotecha A, Wang Q, Dong X, Ilca SL, Ondiviela M, Zihe R, Seago J, Charleston B, Fry EE, Abrescia NGA, Springer TA, Huiskonen JT, Stuart DI.

Nat Commun. 2017 May 23;8:15408. doi: 10.1038/ncomms15408.

13.

A replication-competent foot-and-mouth disease virus expressing a luciferase reporter.

Zhang F, Perez-Martin E, Juleff N, Charleston B, Seago J.

J Virol Methods. 2017 Sep;247:38-44. doi: 10.1016/j.jviromet.2017.05.011. Epub 2017 May 19.

14.

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability.

Scott KA, Kotecha A, Seago J, Ren J, Fry EE, Stuart DI, Charleston B, Maree FF.

J Virol. 2017 Apr 28;91(10). pii: e02312-16. doi: 10.1128/JVI.02312-16. Print 2017 May 15.

15.

The B Cell Response to Foot-and-Mouth Disease Virus in Cattle following Sequential Vaccination with Multiple Serotypes.

Grant CFJ, Carr BV, Kotecha A, van den Born E, Stuart DI, Hammond JA, Charleston B.

J Virol. 2017 Apr 13;91(9). pii: e02157-16. doi: 10.1128/JVI.02157-16. Print 2017 May 1.

16.

Experimental acute infection of alpacas with Bovine viral diarrhea virus 1 subgenotype b alters peripheral blood and GALT leukocyte subsets.

Topliff CL, Alkheraif AA, Kuszynski CA, Davis WC, Steffen DJ, Schmitz JA, Eskridge KM, Charleston B, Henningson JN, Kelling CL.

J Vet Diagn Invest. 2017 Mar;29(2):186-192. doi: 10.1177/1040638717690015. Epub 2017 Feb 6.

PMID:
28166712
17.

Frequency and phenotype of natural killer cells and natural killer cell subsets in bovine lymphoid compartments and blood.

Hamilton CA, Mahan S, Bell CR, Villarreal-Ramos B, Charleston B, Entrican G, Hope JC.

Immunology. 2017 May;151(1):89-97. doi: 10.1111/imm.12708. Epub 2017 Feb 7.

18.

Distinct immune responses and virus shedding in pigs following aerosol, intra-nasal and contact infection with pandemic swine influenza A virus, A(H1N1)09.

Hemmink JD, Morgan SB, Aramouni M, Everett H, Salguero FJ, Canini L, Porter E, Chase-Topping M, Beck K, Loughlin RM, Carr BV, Brown IH, Bailey M, Woolhouse M, Brookes SM, Charleston B, Tchilian E.

Vet Res. 2016 Oct 20;47(1):103.

19.

Transduction of skin-migrating dendritic cells by human adenovirus 5 occurs via an actin-dependent phagocytic pathway.

Guzman E, Taylor G, Hope J, Herbert R, Cubillos-Zapata C, Charleston B.

J Gen Virol. 2016 Oct;97(10):2703-2718. doi: 10.1099/jgv.0.000581. Epub 2016 Aug 15.

20.

Global Foot-and-Mouth Disease Research Update and Gap Analysis: 7 - Pathogenesis and Molecular Biology.

Robinson L, Knight-Jones TJ, Charleston B, Rodriguez LL, Gay CG, Sumption KJ, Vosloo W.

Transbound Emerg Dis. 2016 Jun;63 Suppl 1:63-71. doi: 10.1111/tbed.12520. Review.

PMID:
27320168
21.

Global Foot-and-Mouth Disease Research Update and Gap Analysis: 6 - Immunology.

Robinson L, Knight-Jones TJ, Charleston B, Rodriguez LL, Gay CG, Sumption KJ, Vosloo W.

Transbound Emerg Dis. 2016 Jun;63 Suppl 1:56-62. doi: 10.1111/tbed.12518. Review.

PMID:
27320167
22.

Global Foot-and-Mouth Disease Research Update and Gap Analysis: 5 - Biotherapeutics and Disinfectants.

Robinson L, Knight-Jones TJ, Charleston B, Rodriguez LL, Gay CG, Sumption KJ, Vosloo W.

Transbound Emerg Dis. 2016 Jun;63 Suppl 1:49-55. doi: 10.1111/tbed.12519. Review.

PMID:
27320166
23.

Global Foot-and-Mouth Disease Research Update and Gap Analysis: 4 - Diagnostics.

Knight-Jones TJ, Robinson L, Charleston B, Rodriguez LL, Gay CG, Sumption KJ, Vosloo W.

Transbound Emerg Dis. 2016 Jun;63 Suppl 1:42-8. doi: 10.1111/tbed.12523. Review.

PMID:
27320165
24.

Global Foot-and-Mouth Disease Research Update and Gap Analysis: 3 - Vaccines.

Robinson L, Knight-Jones TJ, Charleston B, Rodriguez LL, Gay CG, Sumption KJ, Vosloo W.

Transbound Emerg Dis. 2016 Jun;63 Suppl 1:30-41. doi: 10.1111/tbed.12521. Review.

PMID:
27320164
25.

Global Foot-and-Mouth Disease Research Update and Gap Analysis: 2 - Epidemiology, Wildlife and Economics.

Knight-Jones TJ, Robinson L, Charleston B, Rodriguez LL, Gay CG, Sumption KJ, Vosloo W.

Transbound Emerg Dis. 2016 Jun;63 Suppl 1:14-29. doi: 10.1111/tbed.12522. Review.

PMID:
27320163
26.

Global Foot-and-Mouth Disease Research Update and Gap Analysis: 1 - Overview of Global Status and Research Needs.

Knight-Jones TJ, Robinson L, Charleston B, Rodriguez LL, Gay CG, Sumption KJ, Vosloo W.

Transbound Emerg Dis. 2016 Jun;63 Suppl 1:3-13. doi: 10.1111/tbed.12528. Review.

PMID:
27320162
27.

The B-cell response to foot-and-mouth-disease virus in cattle following vaccination and live-virus challenge.

Grant CF, Carr BV, Singanallur NB, Morris J, Gubbins S, Hudelet P, Ilott M, Charreyre C, Vosloo W, Charleston B.

J Gen Virol. 2016 Sep;97(9):2201-9. doi: 10.1099/jgv.0.000517. Epub 2016 Jun 2.

28.

Aerosol Delivery of a Candidate Universal Influenza Vaccine Reduces Viral Load in Pigs Challenged with Pandemic H1N1 Virus.

Morgan SB, Hemmink JD, Porter E, Harley R, Shelton H, Aramouni M, Everett HE, Brookes SM, Bailey M, Townsend AM, Charleston B, Tchilian E.

J Immunol. 2016 Jun 15;196(12):5014-23. doi: 10.4049/jimmunol.1502632. Epub 2016 May 6.

29.

Type I and III IFNs Produced by Plasmacytoid Dendritic Cells in Response to a Member of the Flaviviridae Suppress Cellular Immune Responses.

Reid E, Juleff N, Windsor M, Gubbins S, Roberts L, Morgan S, Meyers G, Perez-Martin E, Tchilian E, Charleston B, Seago J.

J Immunol. 2016 May 15;196(10):4214-26. doi: 10.4049/jimmunol.1600049. Epub 2016 Apr 6.

30.

Potency of a thermostabilised chimpanzee adenovirus Rift Valley Fever vaccine in cattle.

Dulal P, Wright D, Ashfield R, Hill AV, Charleston B, Warimwe GM.

Vaccine. 2016 Apr 29;34(20):2296-8. doi: 10.1016/j.vaccine.2016.03.061. Epub 2016 Mar 25.

31.

Application of the thermofluor PaSTRy technique for improving foot-and-mouth disease virus vaccine formulation.

Kotecha A, Zhang F, Juleff N, Jackson T, Perez E, Stuart D, Fry E, Charleston B, Seago J.

J Gen Virol. 2016 Jul;97(7):1557-65. doi: 10.1099/jgv.0.000462. Epub 2016 Mar 22.

32.

Differential Persistence of Foot-and-Mouth Disease Virus in African Buffalo Is Related to Virus Virulence.

Maree F, de Klerk-Lorist LM, Gubbins S, Zhang F, Seago J, Pérez-Martín E, Reid L, Scott K, van Schalkwyk L, Bengis R, Charleston B, Juleff N.

J Virol. 2016 Apr 29;90(10):5132-5140. doi: 10.1128/JVI.00166-16. Print 2016 May 15.

33.

Chimpanzee Adenovirus Vaccine Provides Multispecies Protection against Rift Valley Fever.

Warimwe GM, Gesharisha J, Carr BV, Otieno S, Otingah K, Wright D, Charleston B, Okoth E, Elena LG, Lorenzo G, Ayman el-B, Alharbi NK, Al-dubaib MA, Brun A, Gilbert SC, Nene V, Hill AV.

Sci Rep. 2016 Feb 5;6:20617. doi: 10.1038/srep20617.

34.

Assessment of the enhancement of PLGA nanoparticle uptake by dendritic cells through the addition of natural receptor ligands and monoclonal antibody.

Walters AA, Somavarapu S, Riitho V, Stewart GR, Charleston B, Steinbach F, Graham SP.

Vaccine. 2015 Nov 27;33(48):6588-95. doi: 10.1016/j.vaccine.2015.10.093. Epub 2015 Nov 1.

PMID:
26529067
35.

Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.

Kotecha A, Seago J, Scott K, Burman A, Loureiro S, Ren J, Porta C, Ginn HM, Jackson T, Perez-Martin E, Siebert CA, Paul G, Huiskonen JT, Jones IM, Esnouf RM, Fry EE, Maree FF, Charleston B, Stuart DI.

Nat Struct Mol Biol. 2015 Oct;22(10):788-94. doi: 10.1038/nsmb.3096. Epub 2015 Sep 21.

36.

The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species.

Dicks MD, Guzman E, Spencer AJ, Gilbert SC, Charleston B, Hill AV, Cottingham MG.

Vaccine. 2015 Feb 25;33(9):1121-8. doi: 10.1016/j.vaccine.2015.01.042. Epub 2015 Jan 25.

37.

Laboratory animal models to study foot-and-mouth disease: a review with emphasis on natural and vaccine-induced immunity.

Habiela M, Seago J, Perez-Martin E, Waters R, Windsor M, Salguero FJ, Wood J, Charleston B, Juleff N.

J Gen Virol. 2014 Nov;95(Pt 11):2329-45. doi: 10.1099/vir.0.068270-0. Epub 2014 Jul 7. Review.

38.

Type I and III interferon production in response to RNA viruses.

Reid E, Charleston B.

J Interferon Cytokine Res. 2014 Sep;34(9):649-58. doi: 10.1089/jir.2014.0066. Epub 2014 Jun 23. Review.

PMID:
24956361
39.

Bovine γδ T cells are a major regulatory T cell subset.

Guzman E, Hope J, Taylor G, Smith AL, Cubillos-Zapata C, Charleston B.

J Immunol. 2014 Jul 1;193(1):208-22. doi: 10.4049/jimmunol.1303398. Epub 2014 Jun 2.

40.

Determining the epitope dominance on the capsid of a serotype SAT2 foot-and-mouth disease virus by mutational analyses.

Opperman PA, Rotherham LS, Esterhuysen J, Charleston B, Juleff N, Capozzo AV, Theron J, Maree FF.

J Virol. 2014 Aug;88(15):8307-18. doi: 10.1128/JVI.00470-14. Epub 2014 May 14.

41.

Understanding foot-and-mouth disease virus transmission biology: identification of the indicators of infectiousness.

Chase-Topping ME, Handel I, Bankowski BM, Juleff ND, Gibson D, Cox SJ, Windsor MA, Reid E, Doel C, Howey R, Barnett PV, Woolhouse ME, Charleston B.

Vet Res. 2013 Jul 3;44:46. doi: 10.1186/1297-9716-44-46.

42.

Eradicating bovine viral diarrhoea virus.

Charleston B.

Vet Rec. 2013 Jun 22;172(25):659-60. doi: 10.1136/vr.f4060. No abstract available.

PMID:
23792995
43.

Improved adjuvanting of seasonal influenza vaccines: preclinical studies of MVA-NP+M1 coadministration with inactivated influenza vaccine.

Mullarkey CE, Boyd A, van Laarhoven A, Lefevre EA, Veronica Carr B, Baratelli M, Molesti E, Temperton NJ, Butter C, Charleston B, Lambe T, Gilbert SC.

Eur J Immunol. 2013 Jul;43(7):1940-52. doi: 10.1002/eji.201242922. Epub 2013 Jun 10.

44.

An infectious recombinant foot-and-mouth disease virus expressing a fluorescent marker protein.

Seago J, Juleff N, Moffat K, Berryman S, Christie JM, Charleston B, Jackson T.

J Gen Virol. 2013 Jul;94(Pt 7):1517-27. doi: 10.1099/vir.0.052308-0. Epub 2013 Apr 4.

45.

Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.

Porta C, Kotecha A, Burman A, Jackson T, Ren J, Loureiro S, Jones IM, Fry EE, Stuart DI, Charleston B.

PLoS Pathog. 2013 Mar;9(3):e1003255. doi: 10.1371/journal.ppat.1003255. Epub 2013 Mar 27.

46.

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity.

Porta C, Xu X, Loureiro S, Paramasivam S, Ren J, Al-Khalil T, Burman A, Jackson T, Belsham GJ, Curry S, Lomonossoff GP, Parida S, Paton D, Li Y, Wilsden G, Ferris N, Owens R, Kotecha A, Fry E, Stuart DI, Charleston B, Jones IM.

J Virol Methods. 2013 Feb;187(2):406-12. doi: 10.1016/j.jviromet.2012.11.011. Epub 2012 Nov 19.

47.

Assessment of T-dependent and T-independent immune responses in cattle using a B cell ELISPOT assay.

Grant CF, Lefevre EA, Carr BV, Prentice H, Gubbins S, Pollard AJ, Charreyre C, Charleston B.

Vet Res. 2012 Oct 10;43:68. doi: 10.1186/1297-9716-43-68.

48.

Accumulation of nucleotide substitutions occurring during experimental transmission of foot-and-mouth disease virus.

Juleff N, Valdazo-González B, Wadsworth J, Wright CF, Charleston B, Paton DJ, King DP, Knowles NJ.

J Gen Virol. 2013 Jan;94(Pt 1):108-19. doi: 10.1099/vir.0.046029-0. Epub 2012 Oct 3.

49.

CD4+ T-cell responses to foot-and-mouth disease virus in vaccinated cattle.

Carr BV, Lefevre EA, Windsor MA, Inghese C, Gubbins S, Prentice H, Juleff ND, Charleston B.

J Gen Virol. 2013 Jan;94(Pt 1):97-107. doi: 10.1099/vir.0.045732-0. Epub 2012 Oct 3.

50.

Characterization of epitope-tagged foot-and-mouth disease virus.

Seago J, Jackson T, Doel C, Fry E, Stuart D, Harmsen MM, Charleston B, Juleff N.

J Gen Virol. 2012 Nov;93(Pt 11):2371-81. doi: 10.1099/vir.0.043521-0. Epub 2012 Jul 18.

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