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Items: 39

1.

FDA Approval Summary: Niraparib for the Maintenance Treatment of Patients with Recurrent Ovarian Cancer in Response to Platinum-Based Chemotherapy.

Ison G, Howie LJ, Amiri-Kordestani L, Zhang L, Tang S, Sridhara R, Pierre V, Charlab R, Ramamoorthy A, Song P, Li F, Yu J, Manheng W, Palmby TR, Ghosh S, Horne HN, Lee EY, Philip R, Dave K, Chen XH, Kelly SL, Janoria KG, Banerjee A, Eradiri O, Dinin J, Goldberg KB, Pierce WF, Ibrahim A, Kluetz PG, Blumenthal GM, Beaver JA, Pazdur R.

Clin Cancer Res. 2018 Apr 12. doi: 10.1158/1078-0432.CCR-18-0042. [Epub ahead of print]

PMID:
29650751
2.

Considerations for Developing Targeted Therapies in Low-Frequency Molecular Subsets of a Disease.

Schuck RN, Woodcock J, Zineh I, Stein P, Jarow J, Temple R, Permutt T, LaVange L, Beaver JA, Charlab R, Blumenthal GM, Dorff SE, Leptak C, Lemery S, Rogers H, Chowdhury B, Litwack ED, Pacanowski M.

Clin Pharmacol Ther. 2018 Feb 23. doi: 10.1002/cpt.1041. [Epub ahead of print]

PMID:
29473145
3.

FDA Approval Summary: Rucaparib for the Treatment of Patients with Deleterious BRCA Mutation-Associated Advanced Ovarian Cancer.

Balasubramaniam S, Beaver JA, Horton S, Fernandes LL, Tang S, Horne HN, Liu J, Liu C, Schrieber SJ, Yu J, Song P, Pierce W, Robertson KJ, Palmby TR, Chiu HJ, Lee EY, Philip R, Schuck R, Charlab R, Banerjee A, Chen XH, Wang X, Goldberg KB, Sridhara R, Kim G, Pazdur R.

Clin Cancer Res. 2017 Dec 1;23(23):7165-7170. doi: 10.1158/1078-0432.CCR-17-1337. Epub 2017 Jul 27.

PMID:
28751443
4.

Leveraging Genomic Factors to Improve Benefit-Risk.

Schuck RN, Charlab R, Blumenthal GM.

Clin Transl Sci. 2017 Mar;10(2):78-83. doi: 10.1111/cts.12439. Epub 2017 Feb 3. Review. No abstract available.

5.

Osimertinib for the Treatment of Metastatic EGFR T790M Mutation-Positive Non-Small Cell Lung Cancer.

Khozin S, Weinstock C, Blumenthal GM, Cheng J, He K, Zhuang L, Zhao H, Charlab R, Fan I, Keegan P, Pazdur R.

Clin Cancer Res. 2017 May 1;23(9):2131-2135. doi: 10.1158/1078-0432.CCR-16-1773. Epub 2016 Dec 6.

6.

FDA Approval: Uridine Triacetate for the Treatment of Patients Following Fluorouracil or Capecitabine Overdose or Exhibiting Early-Onset Severe Toxicities Following Administration of These Drugs.

Ison G, Beaver JA, McGuinn WD Jr, Palmby TR, Dinin J, Charlab R, Marathe A, Jin R, Liu Q, Chen XH, Ysern X, Stephens O, Bai G, Wang Y, Dorff SE, Cheng J, Tang S, Sridhara R, Pierce W, McKee AE, Ibrahim A, Kim G, Pazdur R.

Clin Cancer Res. 2016 Sep 15;22(18):4545-9. doi: 10.1158/1078-0432.CCR-16-0638. Epub 2016 Jul 11. Review.

7.

FDA Approval: Palbociclib for the Treatment of Postmenopausal Patients with Estrogen Receptor-Positive, HER2-Negative Metastatic Breast Cancer.

Beaver JA, Amiri-Kordestani L, Charlab R, Chen W, Palmby T, Tilley A, Zirkelbach JF, Yu J, Liu Q, Zhao L, Crich J, Chen XH, Hughes M, Bloomquist E, Tang S, Sridhara R, Kluetz PG, Kim G, Ibrahim A, Pazdur R, Cortazar P.

Clin Cancer Res. 2015 Nov 1;21(21):4760-6. doi: 10.1158/1078-0432.CCR-15-1185. Epub 2015 Aug 31. Review.

8.

FDA Approval: Belinostat for the Treatment of Patients with Relapsed or Refractory Peripheral T-cell Lymphoma.

Lee HZ, Kwitkowski VE, Del Valle PL, Ricci MS, Saber H, Habtemariam BA, Bullock J, Bloomquist E, Li Shen Y, Chen XH, Brown J, Mehrotra N, Dorff S, Charlab R, Kane RC, Kaminskas E, Justice R, Farrell AT, Pazdur R.

Clin Cancer Res. 2015 Jun 15;21(12):2666-70. doi: 10.1158/1078-0432.CCR-14-3119. Epub 2015 Mar 23.

9.

Trial geography, pharmacogenetics, and global drug development.

Schuck RN, Florian J, Charlab R, Pacanowski M.

Clin Pharmacol Ther. 2015 Mar;97(3):218-20. doi: 10.1002/cpt.27. Epub 2014 Dec 15.

PMID:
25669642
10.

Pharmacogenomics: historical perspective and current status.

Charlab R, Zhang L.

Methods Mol Biol. 2013;1015:3-22. doi: 10.1007/978-1-62703-435-7_1.

PMID:
23824846
11.

Clinical pharmacology as a cornerstone of orphan drug development.

Bashaw ED, Huang SM, Coté TR, Pariser AR, Garnett CE, Burckart G, Zhang L, Men AY, Le CD, Charlab R, Gobburu JV, Lesko LJ.

Nat Rev Drug Discov. 2011 Oct 31;10(11):795-6. doi: 10.1038/nrd3595.

PMID:
22037026
12.

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact.

Goodsaid FM, Amur S, Aubrecht J, Burczynski ME, Carl K, Catalano J, Charlab R, Close S, Cornu-Artis C, Essioux L, Fornace AJ Jr, Hinman L, Hong H, Hunt I, Jacobson-Kram D, Jawaid A, Laurie D, Lesko L, Li HH, Lindpaintner K, Mayne J, Morrow P, Papaluca-Amati M, Robison TW, Roth J, Schuppe-Koistinen I, Shi L, Spleiss O, Tong W, Truter SL, Vonderscher J, Westelinck A, Zhang L, Zineh I.

Nat Rev Drug Discov. 2010 Jun;9(6):435-45. doi: 10.1038/nrd3116. Review.

PMID:
20514070
13.

Systematic identification of pseudogenes through whole genome expression evidence profiling.

Yao A, Charlab R, Li P.

Nucleic Acids Res. 2006;34(16):4477-85. Epub 2006 Aug 31.

14.

Gene and alternative splicing annotation with AIR.

Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G.

Genome Res. 2005 Jan;15(1):54-66.

15.

Hemoglobin: Food for thought in vectors and parasites.

Charlab R, Garcia ES.

Parasitol Today. 1997 Sep;13(9):351-3.

PMID:
15275049
16.

An insight into the salivary transcriptome and proteome of the adult female mosquito Culex pipiens quinquefasciatus.

Ribeiro JM, Charlab R, Pham VM, Garfield M, Valenzuela JG.

Insect Biochem Mol Biol. 2004 Jun;34(6):543-63.

PMID:
15147756
17.

Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster.

Zdobnov EM, von Mering C, Letunic I, Torrents D, Suyama M, Copley RR, Christophides GK, Thomasova D, Holt RA, Subramanian GM, Mueller HM, Dimopoulos G, Law JH, Wells MA, Birney E, Charlab R, Halpern AL, Kokoza E, Kraft CL, Lai Z, Lewis S, Louis C, Barillas-Mury C, Nusskern D, Rubin GM, Salzberg SL, Sutton GG, Topalis P, Wides R, Wincker P, Yandell M, Collins FH, Ribeiro J, Gelbart WM, Kafatos FC, Bork P.

Science. 2002 Oct 4;298(5591):149-59.

18.

The genome sequence of the malaria mosquito Anopheles gambiae.

Holt RA, Subramanian GM, Halpern A, Sutton GG, Charlab R, Nusskern DR, Wincker P, Clark AG, Ribeiro JM, Wides R, Salzberg SL, Loftus B, Yandell M, Majoros WH, Rusch DB, Lai Z, Kraft CL, Abril JF, Anthouard V, Arensburger P, Atkinson PW, Baden H, de Berardinis V, Baldwin D, Benes V, Biedler J, Blass C, Bolanos R, Boscus D, Barnstead M, Cai S, Center A, Chaturverdi K, Christophides GK, Chrystal MA, Clamp M, Cravchik A, Curwen V, Dana A, Delcher A, Dew I, Evans CA, Flanigan M, Grundschober-Freimoser A, Friedli L, Gu Z, Guan P, Guigo R, Hillenmeyer ME, Hladun SL, Hogan JR, Hong YS, Hoover J, Jaillon O, Ke Z, Kodira C, Kokoza E, Koutsos A, Letunic I, Levitsky A, Liang Y, Lin JJ, Lobo NF, Lopez JR, Malek JA, McIntosh TC, Meister S, Miller J, Mobarry C, Mongin E, Murphy SD, O'Brochta DA, Pfannkoch C, Qi R, Regier MA, Remington K, Shao H, Sharakhova MV, Sitter CD, Shetty J, Smith TJ, Strong R, Sun J, Thomasova D, Ton LQ, Topalis P, Tu Z, Unger MF, Walenz B, Wang A, Wang J, Wang M, Wang X, Woodford KJ, Wortman JR, Wu M, Yao A, Zdobnov EM, Zhang H, Zhao Q, Zhao S, Zhu SC, Zhimulev I, Coluzzi M, della Torre A, Roth CW, Louis C, Kalush F, Mural RJ, Myers EW, Adams MD, Smith HO, Broder S, Gardner MJ, Fraser CM, Birney E, Bork P, Brey PT, Venter JC, Weissenbach J, Kafatos FC, Collins FH, Hoffman SL.

Science. 2002 Oct 4;298(5591):129-49.

19.

The D7 family of salivary proteins in blood sucking diptera.

Valenzuela JG, Charlab R, Gonzalez EC, de Miranda-Santos IK, Marinotti O, Francischetti IM, Ribeiro JM.

Insect Mol Biol. 2002 Apr;11(2):149-55.

PMID:
11966880
20.

Mycobacterium bovis BCG but not Mycobacterium leprae induces TNF-alpha secretion in human monocytic THP-1 cells.

Oliveira MM, Charlab R, Pessolani MC.

Mem Inst Oswaldo Cruz. 2001 Oct;96(7):973-8.

21.

The salivary adenosine deaminase activity of the mosquitoes Culex quinquefasciatus and Aedes aegypti.

Ribeiro JM, Charlab R, Valenzuela JG.

J Exp Biol. 2001 Jun;204(Pt 11):2001-10.

22.
23.

The invertebrate growth factor/CECR1 subfamily of adenosine deaminase proteins.

Charlab R, Valenzuela JG, Andersen J, Ribeiro JM.

Gene. 2001 Apr 4;267(1):13-22.

PMID:
11311551
24.

Human immune response to sand fly salivary gland antigens: a useful epidemiological marker?

Barral A, Honda E, Caldas A, Costa J, Vinhas V, Rowton ED, Valenzuela JG, Charlab R, Barral-Netto M, Ribeiro JM.

Am J Trop Med Hyg. 2000 Jun;62(6):740-5.

PMID:
11304066
25.

The sequence of the human genome.

Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigó R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X.

Science. 2001 Feb 16;291(5507):1304-51. Erratum in: Science 2001 Jun 5;292(5523):1838.

PMID:
11181995
26.
27.

The salivary adenosine deaminase from the sand fly Lutzomyia longipalpis.

Charlab R, Rowton ED, Ribeiro JM.

Exp Parasitol. 2000 May;95(1):45-53.

PMID:
10864517
28.

Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis.

Valenzuela JG, Charlab R, Mather TN, Ribeiro JM.

J Biol Chem. 2000 Jun 23;275(25):18717-23.

29.

Salivary amylase activity of the phlebotomine sand fly, Lutzomyia longipalpis.

Ribeiro JM, Rowton ED, Charlab R.

Insect Biochem Mol Biol. 2000 Apr;30(4):271-7.

PMID:
10727893
30.

The salivary 5'-nucleotidase/phosphodiesterase of the hematophagus sand fly, Lutzomyia longipalpis [corrected].

Ribeiro JM, Rowton ED, Charlab R.

Insect Biochem Mol Biol. 2000 Apr;30(4):279-85. Erratum in: Insect Biochem Mol Biol 2000 Nov;30(11):1117.

PMID:
10727894
31.

Toward an understanding of the biochemical and pharmacological complexity of the saliva of a hematophagous sand fly Lutzomyia longipalpis.

Charlab R, Valenzuela JG, Rowton ED, Ribeiro JM.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15155-60.

32.

Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius. A new type of nucleotide-binding enzyme.

Valenzuela JG, Charlab R, Galperin MY, Ribeiro JM.

J Biol Chem. 1998 Nov 13;273(46):30583-90.

33.
34.

Cytostatic effect of Lutzomyia longipalpis salivary gland homogenates on Leishmania parasites.

Charlab R, Ribeiro JM.

Am J Trop Med Hyg. 1993 Jun;48(6):831-8.

PMID:
8333578
35.

Granulocyte-macrophage colony-stimulating factor increases the infectivity of Leishmania amazonensis by protecting promastigotes from heat-induced death.

Barcinski MA, Schechtman D, Quintao LG, Costa Dde A, Soares LR, Moreira ME, Charlab R.

Infect Immun. 1992 Sep;60(9):3523-7.

36.

Granulocyte-macrophage colony-stimulating factor is a growth-factor for promastigotes of Leishmania mexicana amazonensis.

Charlab R, Blaineau C, Schechtman D, Barcinski MA.

J Protozool. 1990 Sep-Oct;37(5):352-7.

PMID:
2213649
37.

The role of hematopoietic growth factors in the fate of an infection with Leishmania mexicana amazonensis: an attempt at a unifying hypothesis.

Barcinski MA, Charlab R, Soares LR, Moreira ME, Zalis MG, Magalhães AM.

Mem Inst Oswaldo Cruz. 1988 Nov;83 Suppl 1:411-3. No abstract available.

38.
39.

Investigation of the relationship between sst1 and fdp mutations in yeast and their effect on trehalose synthesis.

Charlab R, Oliveira DE, Panek AD.

Braz J Med Biol Res. 1985;18(4):447-54.

PMID:
2942205

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