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A Pilot Randomized Controlled Trial Comparing Levothyroxine to Placebo in Neurologically Deceased Donors.

Frenette AJ, Williamson D, Williams V, Lagacé AM, Charbonney E, Serri K.

Prog Transplant. 2019 Jun 9:1526924819855083. doi: 10.1177/1526924819855083. [Epub ahead of print]


A Canadian survey of critical care physicians' hemodynamic management of deceased organ donors.

Frenette AJ, Charbonney E, D'Aragon F, Serri K, Marsolais P, Chassé M, Meade M, Williamson D; Canadian Critical Care TrialsGroup.

Can J Anaesth. 2019 Jun 5. doi: 10.1007/s12630-019-01388-7. [Epub ahead of print]


Ventilation During Cardiopulmonary Resuscitation: What Have We Learned From Models?

Charbonney E, Grieco DL, Cordioli RL, Badat B, Savary D, Richard JM; CAVIAR Group.

Respir Care. 2019 May 28. pii: respcare.06998. doi: 10.4187/respcare.06998. [Epub ahead of print]


Comparison of the source and prognostic utility of cfDNA in trauma and sepsis.

Jackson Chornenki NL, Coke R, Kwong AC, Dwivedi DJ, Xu MK, McDonald E, Marshall JC, Fox-Robichaud AE, Charbonney E, Liaw PC.

Intensive Care Med Exp. 2019 May 22;7(1):29. doi: 10.1186/s40635-019-0251-4.


Translaryngeal Tracheostomy Needle Introducer: a simple device to improve safety and reduce complications during Fantoni's translaryngeal tracheostomy procedure: trial on human cadavers.

Terrani A, Bassi E, Valcarenghi C, Charbonney E, Ouellet P, Gosselin P, Bellani G, Foti G.

Intensive Care Med Exp. 2019 Jan 28;7(1):9. doi: 10.1186/s40635-019-0221-x.


A systematic review of interventions to facilitate extubation in patients difficult-to-wean due to delirium, agitation, or anxiety and a meta-analysis of the effect of dexmedetomidine.

Dupuis S, Brindamour D, Karzon S, Frenette AJ, Charbonney E, Perreault MM, Bellemare P, Burry L, Williamson DR.

Can J Anaesth. 2019 Mar;66(3):318-327. doi: 10.1007/s12630-018-01289-1. Epub 2019 Jan 23. Review.


New physiological insights in ventilation during cardiopulmonary resuscitation.

Cordioli RL, Grieco DL, Charbonney E, Richard JC, Savary D.

Curr Opin Crit Care. 2019 Feb;25(1):37-44. doi: 10.1097/MCC.0000000000000573.


Low ventilation associated with chest compression, an old observation that requires new physiological interpretation.

Charbonney E, Savary D, Badat B, Grieco DL, Richard JC; CAVIAR group.

Am J Emerg Med. 2019 Jun;37(6):1212-1213. doi: 10.1016/j.ajem.2018.12.002. Epub 2018 Dec 4. No abstract available.


Caspase-(8/3) activation and organ inflammation in a rat model of resuscitated hemorrhagic shock: A role for uric acid.

Gilbert K, Rousseau G, Bouchard C, Dunberry-Poissant S, Baril F, Cardinal AM, Khazoom F, Vega MA, Brochiero E, Charbonney E.

J Trauma Acute Care Surg. 2019 Mar;86(3):431-439. doi: 10.1097/TA.0000000000002152.


Minimal PaO2 threshold after traumatic brain injury and clinical utility of a novel brain oxygenation ratio.

Dellazizzo L, Demers SP, Charbonney E, Williams V, Serri K, Albert M, Giguère JF, Laroche M, Williamson D, Bernard F.

J Neurosurg. 2018 Oct 1:1-9. doi: 10.3171/2018.5.JNS18651. [Epub ahead of print]


Fluid sparing and norepinephrine use in a rat model of resuscitated haemorrhagic shock: end-organ impact.

Dunberry-Poissant S, Gilbert K, Bouchard C, Baril F, Cardinal AM, L'Ecuyer S, Hylands M, Lamontagne F, Rousseau G, Charbonney E.

Intensive Care Med Exp. 2018 Nov 12;6(1):47. doi: 10.1186/s40635-018-0212-3.


Intrathoracic Airway Closure Impacts CO2 Signal and Delivered Ventilation during Cardiopulmonary Resuscitation.

Grieco DL, J Brochard L, Drouet A, Telias I, Delisle S, Bronchti G, Ricard C, Rigollot M, Badat B, Ouellet P, Charbonney E, Mancebo J, Mercat A, Savary D, Richard JM.

Am J Respir Crit Care Med. 2019 Mar 15;199(6):728-737. doi: 10.1164/rccm.201806-1111OC.


Experience and Perception in Organ Donation: A Matter of Team Work.

Lagacé AM, Charbonney E, Marsolais P.

Crit Care Med. 2018 Jun;46(6):e621. doi: 10.1097/CCM.0000000000003026. No abstract available.


7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial.

Daneman N, Rishu AH, Pinto R, Aslanian P, Bagshaw SM, Carignan A, Charbonney E, Coburn B, Cook DJ, Detsky ME, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Sligl W, Stelfox HT, Wilcox ME, Fowler RA; Canadian Critical Care Trials Group.

Trials. 2018 Feb 17;19(1):111. doi: 10.1186/s13063-018-2474-1.


Mechanical ventilation modulates pro-inflammatory cytokine expression in spinal cord tissue after injury in rats.

Truflandier K, Beaumont E, Charbonney E, Maghni K, de Marchie M, Spahija J.

Neurosci Lett. 2018 Apr 3;671:13-18. doi: 10.1016/j.neulet.2018.01.028. Epub 2018 Jan 31.


Esophageal Manometry and Regional Transpulmonary Pressure in Lung Injury.

Yoshida T, Amato MBP, Grieco DL, Chen L, Lima CAS, Roldan R, Morais CCA, Gomes S, Costa ELV, Cardoso PFG, Charbonney E, Richard JM, Brochard L, Kavanagh BP.

Am J Respir Crit Care Med. 2018 Apr 15;197(8):1018-1026. doi: 10.1164/rccm.201709-1806OC.


A new physiological model for studying the effect of chest compression and ventilation during cardiopulmonary resuscitation: The Thiel cadaver.

Charbonney E, Delisle S, Savary D, Bronchti G, Rigollot M, Drouet A, Badat B, Ouellet P, Gosselin P, Mercat A, Brochard L, Richard JM; CAVIAR.

Resuscitation. 2018 Apr;125:135-142. doi: 10.1016/j.resuscitation.2018.01.012. Epub 2018 Jan 6.


S100A8/A9 and sRAGE kinetic after polytrauma; an explorative observational study.

Joly P, Marshall JC, Tessier PA, Massé C, Page N, Frenette AJ, Khazoom F, Le Guillan S, Berthiaume Y, Charbonney E.

Scand J Trauma Resusc Emerg Med. 2017 Nov 25;25(1):114. doi: 10.1186/s13049-017-0455-0.


Early vasopressor use following traumatic injury: a systematic review.

Hylands M, Toma A, Beaudoin N, Frenette AJ, D'Aragon F, Belley-Côté É, Charbonney E, Møller MH, Laake JH, Vandvik PO, Siemieniuk RA, Rochwerg B, Lauzier F, Green RS, Ball I, Scales D, Murthy S, Kwong JSW, Guyatt G, Rizoli S, Asfar P, Lamontagne F.

BMJ Open. 2017 Nov 17;7(11):e017559. doi: 10.1136/bmjopen-2017-017559. Review.


Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study.

Duan EH, Adhikari NKJ, D'Aragon F, Cook DJ, Mehta S, Alhazzani W, Goligher E, Charbonney E, Arabi YM, Karachi T, Turgeon AF, Hand L, Zhou Q, Austin P, Friedrich J, Lamontagne F, Lauzier F, Patel R, Muscedere J, Hall R, Aslanian P, Piraino T, Albert M, Bagshaw SM, Jacka M, Wood G, Henderson W, Dorscheid D, Ferguson ND, Meade MO; Canadian Critical Care Trials Group.

Ann Am Thorac Soc. 2017 Dec;14(12):1818-1826. doi: 10.1513/AnnalsATS.201612-1042OC.


Invited Response to "Potential Disadvantages of Over Centralization of Organ Recovery Centers: Response to Marsolais et al."

Marsolais P, Charbonney E, Serri K, Lagacé AM, Bernard F, Albert M.

Am J Transplant. 2017 Sep;17(9):2492-2493. doi: 10.1111/ajt.14411. Epub 2017 Jul 21. No abstract available.


A systematic review of vasopressor blood pressure targets in critically ill adults with hypotension.

Hylands M, Moller MH, Asfar P, Toma A, Frenette AJ, Beaudoin N, Belley-Côté É, D'Aragon F, Laake JH, Siemieniuk RA, Charbonney E, Lauzier F, Kwong J, Rochwerg B, Vandvik PO, Guyatt G, Lamontagne F.

Can J Anaesth. 2017 Jul;64(7):703-715. doi: 10.1007/s12630-017-0877-1. Epub 2017 May 11. Review.


Capnographic waveforms obtained in experimental Thiel cadaver model after intubation.

Savary D, Charbonney E, Delisle S, Marceau R, Paul O, Gilles B, Jean-Christophe R; CAVIAR Group of Researchers.

Resuscitation. 2017 Jul;116:e1-e2. doi: 10.1016/j.resuscitation.2017.05.002. Epub 2017 May 6. No abstract available.


Vasopressor use following traumatic injury - A single center retrospective study.

Hylands M, Godbout MP, Mayer SK, Fraser WD, Vanasse A, Leclair MA, Turgeon AF, Lauzier F, Charbonney E, Trottier V, Razek TS, Roy A, D'Aragon F, Belley-Côté E, Day AG, Le Guillan S, Sabbagh R, Lamontagne F.

PLoS One. 2017 Apr 27;12(4):e0176587. doi: 10.1371/journal.pone.0176587. eCollection 2017.


Systemic angiopoietin-1/2 dysregulation following cardiopulmonary bypass in adults.

Charbonney E, Wilcox E, Shan Y, d'Empaire PP, Duggal A, Rubenfeld GD, Liles C, Santos CD.

Future Sci OA. 2017 Jan 11;3(1):FSO166. doi: 10.4155/fsoa-2016-0072. eCollection 2017 Mar.


Vasopressor use following traumatic injury: protocol for a systematic review.

Hylands M, Toma A, Beaudoin N, Frenette AJ, D'Aragon F, Belley-Côté E, Hylander M, Lauzier F, Siemieniuk RA, Charbonney E, Kwong J, Laake JH, Guyatt G, Vandvik PO, Rochwerg B, Green R, Ball I, Scales D, Murthy S, Rizoli S, Asfar P, Lamontagne F.

BMJ Open. 2017 Feb 28;7(2):e014166. doi: 10.1136/bmjopen-2016-014166.


Vasopressor Use for Severe Hypotension-A Multicentre Prospective Observational Study.

Lamontagne F, Cook DJ, Meade MO, Seely A, Day AG, Charbonney E, Serri K, Skrobik Y, Hebert P, St-Arnaud C, Quiroz-Martinez H, Mayette M, Heyland DK.

PLoS One. 2017 Jan 20;12(1):e0167840. doi: 10.1371/journal.pone.0167840. eCollection 2017.


Spinal cord injury modulates the lung inflammatory response in mechanically ventilated rats: a comparative animal study.

Truflandier K, Beaumont E, Maghni K, De Marchie M, Charbonney E, Spahija J.

Physiol Rep. 2016 Dec;4(24). pii: e13009. doi: 10.14814/phy2.13009.


The First 2 Years of Activity of a Specialized Organ Procurement Center: Report of an Innovative Approach to Improve Organ Donation.

Marsolais P, Durand P, Charbonney E, Serri K, Lagacé AM, Bernard F, Albert M.

Am J Transplant. 2017 Jun;17(6):1613-1619. doi: 10.1111/ajt.14139. Epub 2017 Jan 7.


Pharmacological interventions for agitation in patients with traumatic brain injury: protocol for a systematic review and meta-analysis.

Williamson DR, Frenette AJ, Burry L, Perreault MM, Charbonney E, Lamontagne F, Potvin MJ, Giguère JF, Mehta S, Bernard F.

Syst Rev. 2016 Nov 17;5(1):193.


Patient-Ventilator Asynchrony due to Reverse Triggering Occurring in Brain-Dead Patients: Clinical Implications and Physiological Meaning.

Delisle S, Charbonney E, Albert M, Ouellet P, Marsolais P, Rigollot M, Savary D, Richard JM, Serri K.

Am J Respir Crit Care Med. 2016 Nov 1;194(9):1166-1168. No abstract available.


The authors reply.

Charbonney E, Marshall JC.

Crit Care Med. 2016 Oct;44(10):e1006-7. doi: 10.1097/CCM.0000000000001979. No abstract available.


Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src.

Tsang JL, Jia SH, Parodo J, Plant P, Lodyga M, Charbonney E, Szaszi K, Kapus A, Marshall JC.

PLoS One. 2016 Apr 21;11(4):e0153946. doi: 10.1371/journal.pone.0153946. eCollection 2016.


Confirming placement of nasogastric feeding tubes.

Lortie MA, Charbonney E.

CMAJ. 2016 Mar 15;188(5):E96. doi: 10.1503/cmaj.150609. Epub 2015 Nov 9. No abstract available.


Endotoxemia Following Multiple Trauma: Risk Factors and Prognostic Implications.

Charbonney E, Tsang JY, Li Y, Klein D, Duque P, Romaschin A, Marshall JC.

Crit Care Med. 2016 Feb;44(2):335-41. doi: 10.1097/CCM.0000000000001404.


Is It Time to Revisit Surgical Lung Biopsy in ARDS?

Charbonney E, Grondin-Beaudoin B, Eggimann P.

Ann Thorac Surg. 2015 May;99(5):1865. doi: 10.1016/j.athoracsur.2014.11.025. No abstract available.


Low C-reactive protein values at admission predict mortality in patients with severe community-acquired pneumonia caused by Streptococcus pneumoniae that require intensive care management.

Que YA, Virgini V, Lozeron ED, Paratte G, Prod'hom G, Revelly JP, Pagani JL, Charbonney E, Eggimann P.

Infection. 2015 Apr;43(2):193-9. doi: 10.1007/s15010-015-0755-0. Epub 2015 Mar 3.


Oral neutrophils are an independent marker of the systemic inflammatory response after cardiac bypass.

Wilcox ME, Charbonney E, d'Empaire PP, Duggal A, Pinto R, Javid A, Dos Santos C, Rubenfeld GD, Sutherland S, Liles WC, Glogauer M.

J Inflamm (Lond). 2014 Oct 18;11(1):32. doi: 10.1186/s12950-014-0032-5. eCollection 2014.


Activated neutrophils induce epithelial cell apoptosis through oxidant-dependent tyrosine dephosphorylation of caspase-8.

Jia SH, Parodo J, Charbonney E, Tsang JLY, Jia SY, Rotstein OD, Kapus A, Marshall JC.

Am J Pathol. 2014 Apr;184(4):1030-1040. doi: 10.1016/j.ajpath.2013.12.031. Epub 2014 Feb 28.


Extracorporeal membrane oxygenation in diffuse alveolar hemorrhage secondary to systemic lupus erythematosus.

Pacheco Claudio C, Charbonney E, Durand M, Kolan C, Laskine M.

J Clin Med Res. 2014 Apr;6(2):145-8. doi: 10.14740/jocmr1685w. Epub 2014 Feb 6.


Acute refractory hypoxemia after chest trauma reversed by high-frequency oscillatory ventilation: a case report.

Charbonney E, Tsang JL, Wassermann J, Adhikari NK.

J Med Case Rep. 2013 Jul 15;7:186. doi: 10.1186/1752-1947-7-186.


How do your contacts (or their absence) shape your fate?

Charbonney E, Speight P, Kapus A.

Tissue Barriers. 2013 Jan 1;1(1):e23699. doi: 10.4161/tisb.23699.


Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex.

Pagano S, Satta N, Werling D, Offord V, de Moerloose P, Charbonney E, Hochstrasser D, Roux-Lombard P, Vuilleumier N.

J Intern Med. 2012 Oct;272(4):344-57. doi: 10.1111/j.1365-2796.2012.02530.x. Epub 2012 Mar 26.


β-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition.

Charbonney E, Speight P, Masszi A, Nakano H, Kapus A.

Mol Biol Cell. 2011 Dec;22(23):4472-85. doi: 10.1091/mbc.E11-04-0335. Epub 2011 Sep 30.


Human neutrophil peptides mediate endothelial-monocyte interaction, foam cell formation, and platelet activation.

Quinn KL, Henriques M, Tabuchi A, Han B, Yang H, Cheng WE, Tole S, Yu H, Luo A, Charbonney E, Tullis E, Lazarus A, Robinson LA, Ni H, Peterson BR, Kuebler WM, Slutsky AS, Zhang H.

Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2070-9. doi: 10.1161/ATVBAHA.111.227116. Epub 2011 Aug 4. Erratum in: Arterioscler Thromb Vasc Biol. 2012 Jan;32(1):e12.


Anti-apolipoprotein A-1 IgG as an independent cardiovascular prognostic marker affecting basal heart rate in myocardial infarction.

Vuilleumier N, Rossier MF, Pagano S, Python M, Charbonney E, Nkoulou R, James R, Reber G, Mach F, Roux-Lombard P.

Eur Heart J. 2010 Apr;31(7):815-23. doi: 10.1093/eurheartj/ehq055. Epub 2010 Feb 22.


Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3.

Masszi A, Speight P, Charbonney E, Lodyga M, Nakano H, Szászi K, Kapus A.

J Cell Biol. 2010 Feb 8;188(3):383-99. doi: 10.1083/jcb.200906155. Epub 2010 Feb 1.


Prognosis of acute kidney injury requiring renal replacement therapy in solid organ transplanted patients.

Charbonney E, Saudan P, Triverio PA, Quinn K, Mentha G, Martin PY.

Transpl Int. 2009 Nov;22(11):1058-63. doi: 10.1111/j.1432-2277.2009.00914.x. Epub 2009 Jul 13.


Impact of bedside open lung biopsies on the management of mechanically ventilated immunocompromised patients with acute respiratory distress syndrome of unknown etiology.

Charbonney E, Robert J, Pache JC, Chevrolet JC, Eggimann P.

J Crit Care. 2009 Mar;24(1):122-8. doi: 10.1016/j.jcrc.2008.01.008. Epub 2008 Apr 18.


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