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Items: 1 to 50 of 53

1.

Beyond Singular Climatic Variables-Identifying the Dynamics of Wholesome Thermo-Physiological Factors for Existing/Future Human Thermal Comfort during Hot Dry Mediterranean Summers.

Santos Nouri A, Charalampopoulos I, Matzarakis A.

Int J Environ Res Public Health. 2018 Oct 25;15(11). pii: E2362. doi: 10.3390/ijerph15112362.

2.

The Synthetic Microneurotrophin BNN27 Affects Retinal Function in Rats With Streptozotocin-Induced Diabetes.

Ibán-Arias R, Lisa S, Mastrodimou N, Kokona D, Koulakis E, Iordanidou P, Kouvarakis A, Fothiadaki M, Papadogkonaki S, Sotiriou A, Katerinopoulos HE, Gravanis A, Charalampopoulos I, Thermos K.

Diabetes. 2018 Feb;67(2):321-333. doi: 10.2337/db17-0391. Epub 2017 Dec 5.

3.

DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway.

Alexaki VI, Fodelianaki G, Neuwirth A, Mund C, Kourgiantaki A, Ieronimaki E, Lyroni K, Troullinaki M, Fujii C, Kanczkowski W, Ziogas A, Peitzsch M, Grossklaus S, Sönnichsen B, Gravanis A, Bornstein SR, Charalampopoulos I, Tsatsanis C, Chavakis T.

Mol Psychiatry. 2018 Jun;23(6):1410-1420. doi: 10.1038/mp.2017.167. Epub 2017 Sep 12.

PMID:
28894299
4.

The novel synthetic microneurotrophin BNN27 protects mature oligodendrocytes against cuprizone-induced death, through the NGF receptor TrkA.

Bonetto G, Charalampopoulos I, Gravanis A, Karagogeos D.

Glia. 2017 Aug;65(8):1376-1394. doi: 10.1002/glia.23170. Epub 2017 Jun 1.

PMID:
28567989
5.

BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the "weaver" mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor.

Botsakis K, Mourtzi T, Panagiotakopoulou V, Vreka M, Stathopoulos GT, Pediaditakis I, Charalampopoulos I, Gravanis A, Delis F, Antoniou K, Zisimopoulos D, Georgiou CD, Panagopoulos NT, Matsokis N, Angelatou F.

Neuropharmacology. 2017 Jul 15;121:140-157. doi: 10.1016/j.neuropharm.2017.04.043. Epub 2017 Apr 28.

PMID:
28461162
6.

Synthetic microneurotrophins in therapeutics of neurodegeneration.

Gravanis A, Pediaditakis I, Charalampopoulos I.

Oncotarget. 2017 Feb 7;8(6):9005-9006. doi: 10.18632/oncotarget.14667. No abstract available.

7.

BNN27, a 17-Spiroepoxy Steroid Derivative, Interacts With and Activates p75 Neurotrophin Receptor, Rescuing Cerebellar Granule Neurons from Apoptosis.

Pediaditakis I, Kourgiantaki A, Prousis KC, Potamitis C, Xanthopoulos KP, Zervou M, Calogeropoulou T, Charalampopoulos I, Gravanis A.

Front Pharmacol. 2016 Dec 26;7:512. doi: 10.3389/fphar.2016.00512. eCollection 2016.

8.

Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation.

Pediaditakis I, Efstathopoulos P, Prousis KC, Zervou M, Arévalo JC, Alexaki VI, Nikoletopoulou V, Karagianni E, Potamitis C, Tavernarakis N, Chavakis T, Margioris AN, Venihaki M, Calogeropoulou T, Charalampopoulos I, Gravanis A.

Neuropharmacology. 2016 Dec;111:266-282. doi: 10.1016/j.neuropharm.2016.09.007. Epub 2016 Sep 9.

PMID:
27618740
9.

Fingolimod induces neurogenesis in adult mouse hippocampus and improves contextual fear memory.

Efstathopoulos P, Kourgiantaki A, Karali K, Sidiropoulou K, Margioris AN, Gravanis A, Charalampopoulos I.

Transl Psychiatry. 2015 Nov 24;5:e685. doi: 10.1038/tp.2015.179.

10.

Application of multispectral imaging detects areas with neuronal myelin loss, without tissue labelling.

Vazgiouraki E, Papadakis VM, Efstathopoulos P, Lazaridis I, Charalampopoulos I, Fotakis C, Gravanis A.

Microscopy (Oxf). 2016 Apr;65(2):109-18. doi: 10.1093/jmicro/dfv349. Epub 2015 Oct 28.

PMID:
26510556
11.

Data in support on the shape of Schwann cells and sympathetic neurons onto microconically structured silicon surfaces.

Simitzi C, Efstathopoulos P, Kourgiantaki A, Ranella A, Charalampopoulos I, Fotakis C, Αthanassakis Ι, Stratakis E, Gravanis A.

Data Brief. 2015 Jul 31;4:636-40. doi: 10.1016/j.dib.2015.07.030. eCollection 2015 Sep.

12.

Laser fabricated discontinuous anisotropic microconical substrates as a new model scaffold to control the directionality of neuronal network outgrowth.

Simitzi C, Efstathopoulos P, Kourgiantaki A, Ranella A, Charalampopoulos I, Fotakis C, Athanassakis I, Stratakis E, Gravanis A.

Biomaterials. 2015 Oct;67:115-28. doi: 10.1016/j.biomaterials.2015.07.008. Epub 2015 Jul 13.

PMID:
26210178
13.

Effects of novel synthetic microneurotrophins in diabetic retinopathy.

Lisa S, Iban-Arias R, Kokona D, Charalampopoulos I, Gravanis A, Thermos K.

Springerplus. 2015 Jun 12;4(Suppl 1):L25. doi: 10.1186/2193-1801-4-S1-L25. eCollection 2015. No abstract available.

14.

A note on the evolution of the daily pattern of thermal comfort-related micrometeorological parameters in small urban sites in Athens.

Charalampopoulos I, Tsiros I, Chronopoulou-Sereli A, Matzarakis A.

Int J Biometeorol. 2015 Sep;59(9):1223-36. doi: 10.1007/s00484-014-0934-1. Epub 2014 Nov 12.

PMID:
25388948
15.

Dehydroepiandrosterone: an ancestral ligand of neurotrophin receptors.

Pediaditakis I, Iliopoulos I, Theologidis I, Delivanoglou N, Margioris AN, Charalampopoulos I, Gravanis A.

Endocrinology. 2015 Jan;156(1):16-23. doi: 10.1210/en.2014-1596.

PMID:
25330101
16.

Differential effects of dehydroepiandrosterone and testosterone in prostate and colon cancer cell apoptosis: the role of nerve growth factor (NGF) receptors.

Anagnostopoulou V, Pediaditakis I, Alkahtani S, Alarifi SA, Schmidt EM, Lang F, Gravanis A, Charalampopoulos I, Stournaras C.

Endocrinology. 2013 Jul;154(7):2446-56. doi: 10.1210/en.2012-2249. Epub 2013 May 21.

PMID:
23696568
17.

Genetic dissection of neurotrophin signaling through the p75 neurotrophin receptor.

Charalampopoulos I, Vicario A, Pediaditakis I, Gravanis A, Simi A, Ibáñez CF.

Cell Rep. 2012 Dec 27;2(6):1563-70. doi: 10.1016/j.celrep.2012.11.009. Epub 2012 Dec 20.

18.

Neurosteroids and microneurotrophins signal through NGF receptors to induce prosurvival signaling in neuronal cells.

Gravanis A, Calogeropoulou T, Panoutsakopoulou V, Thermos K, Neophytou C, Charalampopoulos I.

Sci Signal. 2012 Oct 16;5(246):pt8. doi: 10.1126/scisignal.2003387.

PMID:
23074265
19.

APRIL binding to BCMA activates a JNK2-FOXO3-GADD45 pathway and induces a G2/M cell growth arrest in liver cells.

Notas G, Alexaki VI, Kampa M, Pelekanou V, Charalampopoulos I, Sabour-Alaoui S, Pediaditakis I, Dessirier V, Gravanis A, Stathopoulos EN, Tsapis A, Castanas E.

J Immunol. 2012 Nov 15;189(10):4748-58. doi: 10.4049/jimmunol.1102891. Epub 2012 Oct 15.

20.

Pasireotide (SOM230) protects the retina in animal models of ischemia induced retinopathies.

Kokona D, Mastrodimou N, Pediaditakis I, Charalampopoulos I, Schmid HA, Thermos K.

Exp Eye Res. 2012 Oct;103:90-8. doi: 10.1016/j.exer.2012.08.005. Epub 2012 Sep 1.

PMID:
22960304
21.

The neurosteroid dehydroepiandrosterone (DHEA) protects the retina from AMPA-induced excitotoxicity: NGF TrkA receptor involvement.

Kokona D, Charalampopoulos I, Pediaditakis I, Gravanis A, Thermos K.

Neuropharmacology. 2012 Apr;62(5-6):2106-17. doi: 10.1016/j.neuropharm.2012.01.006. Epub 2012 Jan 17.

PMID:
22269901
22.

ERα17p, an ERα P295 -T311 fragment, modifies the migration of breast cancer cells, through actin cytoskeleton rearrangements.

Kampa M, Pelekanou V, Gallo D, Notas G, Troullinaki M, Pediaditakis I, Charalampopoulos I, Jacquot Y, Leclercq G, Castanas E.

J Cell Biochem. 2011 Dec;112(12):3786-96. doi: 10.1002/jcb.23309.

PMID:
21826705
23.

Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis.

Lazaridis I, Charalampopoulos I, Alexaki VI, Avlonitis N, Pediaditakis I, Efstathopoulos P, Calogeropoulou T, Castanas E, Gravanis A.

PLoS Biol. 2011 Apr;9(4):e1001051. doi: 10.1371/journal.pbio.1001051. Epub 2011 Apr 26.

24.

Matrix metalloproteinase-9 participates in NGF-induced α-secretase cleavage of amyloid-β protein precursor in PC12 cells.

Fragkouli A, Tzinia AK, Charalampopoulos I, Gravanis A, Tsilibary EC.

J Alzheimers Dis. 2011;24(4):705-19. doi: 10.3233/JAD-2011-101893.

PMID:
21321391
25.

Novel dehydroepiandrosterone derivatives with antiapoptotic, neuroprotective activity.

Calogeropoulou T, Avlonitis N, Minas V, Alexi X, Pantzou A, Charalampopoulos I, Zervou M, Vergou V, Katsanou ES, Lazaridis I, Alexis MN, Gravanis A.

J Med Chem. 2009 Nov 12;52(21):6569-87. doi: 10.1021/jm900468p.

PMID:
19845386
26.

Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor.

Vilar M, Charalampopoulos I, Kenchappa RS, Reversi A, Klos-Applequist JM, Karaca E, Simi A, Spuch C, Choi S, Friedman WJ, Ericson J, Schiavo G, Carter BD, Ibáñez CF.

J Cell Sci. 2009 Sep 15;122(Pt 18):3351-7. doi: 10.1242/jcs.055061. Epub 2009 Aug 25.

27.

Dehydroepiandrosterone protects human keratinocytes against apoptosis through membrane binding sites.

Alexaki VI, Charalampopoulos I, Panayotopoulou M, Kampa M, Gravanis A, Castanas E.

Exp Cell Res. 2009 Aug 1;315(13):2275-83. doi: 10.1016/j.yexcr.2009.04.006. Epub 2009 Apr 18.

PMID:
19379733
28.

Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers.

Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PI, Verveer PJ, Carter BD, Ibáñez CF.

Neuron. 2009 Apr 16;62(1):72-83. doi: 10.1016/j.neuron.2009.02.020.

29.

Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells.

Papadopoulou N, Charalampopoulos I, Anagnostopoulou V, Konstantinidis G, Föller M, Gravanis A, Alevizopoulos K, Lang F, Stournaras C.

Mol Cancer. 2008 Dec 3;7:88. doi: 10.1186/1476-4598-7-88.

30.
31.

Neurosteroids as modulators of neurogenesis and neuronal survival.

Charalampopoulos I, Remboutsika E, Margioris AN, Gravanis A.

Trends Endocrinol Metab. 2008 Oct;19(8):300-7. doi: 10.1016/j.tem.2008.07.004. Epub 2008 Sep 2. Review.

PMID:
18771935
32.

Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells.

Papadopoulou N, Charalampopoulos I, Alevizopoulos K, Gravanis A, Stournaras C.

Exp Cell Res. 2008 Oct 15;314(17):3162-74. doi: 10.1016/j.yexcr.2008.07.012. Epub 2008 Jul 25.

PMID:
18694745
33.

Corticotropin-releasing factor (CRF) and the urocortins differentially regulate catecholamine secretion in human and rat adrenals, in a CRF receptor type-specific manner.

Dermitzaki E, Tsatsanis C, Minas V, Chatzaki E, Charalampopoulos I, Venihaki M, Androulidaki A, Lambropoulou M, Spiess J, Michalodimitrakis E, Gravanis A, Margioris AN.

Endocrinology. 2007 Apr;148(4):1524-38. Epub 2006 Dec 28.

PMID:
17194738
34.

Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging.

Charalampopoulos I, Alexaki VI, Tsatsanis C, Minas V, Dermitzaki E, Lasaridis I, Vardouli L, Stournaras C, Margioris AN, Castanas E, Gravanis A.

Ann N Y Acad Sci. 2006 Nov;1088:139-52. Review.

PMID:
17192562
35.

Peripheral factors in the metabolic syndrome: the pivotal role of adiponectin.

Tsatsanis C, Zacharioudaki V, Androulidaki A, Dermitzaki E, Charalampopoulos I, Minas V, Gravanis A, Margioris AN.

Ann N Y Acad Sci. 2006 Nov;1083:185-95.

PMID:
17148740
36.

Neuropeptide urocortin and its receptors are expressed in rat Kupffer cells.

Charalampopoulos I, Androulidaki A, Minas V, Chatzaki E, Tsatsanis C, Notas G, Xidakis C, Kolios G, Kouroumalis E, Margioris AN, Gravanis A.

Neuroendocrinology. 2006;84(1):49-57. Epub 2006 Nov 3.

PMID:
17090973
37.

Neuronal differentiation of PC12 cells abolishes the expression of membrane androgen receptors.

Alexaki VI, Dermitzaki E, Charalampopoulos I, Kampa M, Nifli AP, Gravanis A, Margioris AN, Castanas E.

Exp Cell Res. 2006 Sep 10;312(15):2745-56. Epub 2006 May 16.

PMID:
16822503
38.

Activation of membrane androgen receptors potentiates the antiproliferative effects of paclitaxel on human prostate cancer cells.

Kampa M, Kogia C, Theodoropoulos PA, Anezinis P, Charalampopoulos I, Papakonstanti EA, Stathopoulos EN, Hatzoglou A, Stournaras C, Gravanis A, Castanas E.

Mol Cancer Ther. 2006 May;5(5):1342-51.

39.

Expression of urocortin in the extravillous human trophoblast at the implantation site.

Bamberger CM, Minas V, Bamberger AM, Charalampopoulos I, Fragouli Y, Schulte HM, Makrigiannakis A.

Placenta. 2007 Feb-Mar;28(2-3):127-32. Epub 2006 May 12.

PMID:
16698078
40.

Corticotropin-releasing factor and the urocortins induce the expression of TLR4 in macrophages via activation of the transcription factors PU.1 and AP-1.

Tsatsanis C, Androulidaki A, Alissafi T, Charalampopoulos I, Dermitzaki E, Roger T, Gravanis A, Margioris AN.

J Immunol. 2006 Feb 1;176(3):1869-77.

41.

Activation of membrane estrogen receptors induce pro-survival kinases.

Alexaki VI, Charalampopoulos I, Kampa M, Nifli AP, Hatzoglou A, Gravanis A, Castanas E.

J Steroid Biochem Mol Biol. 2006 Feb;98(2-3):97-110. Epub 2006 Jan 18.

PMID:
16414261
42.

G protein-associated, specific membrane binding sites mediate the neuroprotective effect of dehydroepiandrosterone.

Charalampopoulos I, Alexaki VI, Lazaridis I, Dermitzaki E, Avlonitis N, Tsatsanis C, Calogeropoulou T, Margioris AN, Castanas E, Gravanis A.

FASEB J. 2006 Mar;20(3):577-9. Epub 2006 Jan 11.

PMID:
16407456
43.

Corticotropin-releasing hormone modulates human trophoblast invasion through carcinoembryonic antigen-related cell adhesion molecule-1 regulation.

Bamberger AM, Minas V, Kalantaridou SN, Radde J, Sadeghian H, Löning T, Charalampopoulos I, Brümmer J, Wagener C, Bamberger CM, Schulte HM, Chrousos GP, Makrigiannakis A.

Am J Pathol. 2006 Jan;168(1):141-50.

44.

Adiponectin induces TNF-alpha and IL-6 in macrophages and promotes tolerance to itself and other pro-inflammatory stimuli.

Tsatsanis C, Zacharioudaki V, Androulidaki A, Dermitzaki E, Charalampopoulos I, Minas V, Gravanis A, Margioris AN.

Biochem Biophys Res Commun. 2005 Oct 7;335(4):1254-63.

PMID:
16115611
45.

Urocortin 1 and Urocortin 2 induce macrophage apoptosis via CRFR2.

Tsatsanis C, Androulidaki A, Dermitzaki E, Charalampopoulos I, Spiess J, Gravanis A, Margioris AN.

FEBS Lett. 2005 Aug 15;579(20):4259-64.

46.

Opposing effects of estradiol- and testosterone-membrane binding sites on T47D breast cancer cell apoptosis.

Kampa M, Nifli AP, Charalampopoulos I, Alexaki VI, Theodoropoulos PA, Stathopoulos EN, Gravanis A, Castanas E.

Exp Cell Res. 2005 Jul 1;307(1):41-51. Epub 2005 Apr 7.

PMID:
15922725
47.

Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization.

Charalampopoulos I, Dermitzaki E, Vardouli L, Tsatsanis C, Stournaras C, Margioris AN, Gravanis A.

Endocrinology. 2005 Aug;146(8):3309-18. Epub 2005 Apr 28.

PMID:
15860555
48.

Corticotropin-releasing hormone activates protein kinase C in an isoenzyme-specific manner.

Dermitzaki E, Tsatsanis C, Charalampopoulos I, Androulidaki A, Alexaki VI, Castanas E, Gravanis A, Margioris AN.

Biochem Biophys Res Commun. 2005 Feb 18;327(3):828-36.

PMID:
15649420
49.

Membrane androgen receptor activation induces apoptotic regression of human prostate cancer cells in vitro and in vivo.

Hatzoglou A, Kampa M, Kogia C, Charalampopoulos I, Theodoropoulos PA, Anezinis P, Dambaki C, Papakonstanti EA, Stathopoulos EN, Stournaras C, Gravanis A, Castanas E.

J Clin Endocrinol Metab. 2005 Feb;90(2):893-903. Epub 2004 Dec 7.

PMID:
15585562
50.

Estrogen exerts neuroprotective effects via membrane estrogen receptors and rapid Akt/NOS activation.

Alexaki VI, Charalampopoulos I, Kampa M, Vassalou H, Theodoropoulos P, Stathopoulos EN, Hatzoglou A, Gravanis A, Castanas E.

FASEB J. 2004 Oct;18(13):1594-6. Epub 2004 Aug 2.

PMID:
15289442

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