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"It's Not Like Taking Chocolates": Factors Influencing the Feasibility and Sustainability of Universal Test and Treat in Correctional Health Systems in Zambia and South Africa.

Topp SM, Chetty-Makkan CM, Smith HJ, Chimoyi L, Hoffmann CJ, Fielding K, Reid SE, Olivier AJ, Hausler H, Herce ME, Charalambous S.

Glob Health Sci Pract. 2019 Jun 27;7(2):189-202. doi: 10.9745/GHSP-D-19-00051. Print 2019 Jun.


HIV incidence and predictors of inconsistent condom use among adult men enrolled into an HIV vaccine preparedness study, Rustenburg, South Africa.

Maenetje P, Lindan C, Makkan H, Chetty-Makkan CM, Latka MH, Charalambous S, Mlotshwa M, Malefo M, Brumskine W, Hills NK, Price MA, Edward V.

PLoS One. 2019 Apr 3;14(4):e0214786. doi: 10.1371/journal.pone.0214786. eCollection 2019.


"To speak or not to speak": A qualitative analysis on the attitude and willingness of women to start conversations about voluntary medical male circumcision with their partners in a peri-urban area, South Africa.

Chetty-Makkan CM, Grund JM, Munyai R, Gadla V, Chihota V, Maraisane M, Charalambous S.

PLoS One. 2019 Jan 25;14(1):e0210480. doi: 10.1371/journal.pone.0210480. eCollection 2019.


What causes symptoms suggestive of tuberculosis in HIV-positive people with negative initial investigations?

Hanifa Y, Toro Silva S, Karstaedt A, Sahid F, Charalambous S, Chihota VN, Churchyard GJ, von Gottberg A, McCarthy K, Nicol MP, Ndlovu NT, Stevens W, Fielding KL, Grant AD.

Int J Tuberc Lung Dis. 2019 Feb 1;23(2):157-165. doi: 10.5588/ijtld.18.0251. Epub 2019 Jan 24.


A Population Pharmacokinetic Analysis Shows that Arylacetamide Deacetylase (AADAC) Gene Polymorphism and HIV Infection Affect the Exposure of Rifapentine.

Francis J, Zvada SP, Denti P, Hatherill M, Charalambous S, Mungofa S, Dawson R, Dorman S, Gupte N, Wiesner L, Jindani A, Harrison TS, Olagunju A, Egan D, Owen A, McIlleron HM.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e01964-18. doi: 10.1128/AAC.01964-18. Print 2019 Apr.


TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB - a study protocol.

Rachow A, Ivanova O, Wallis R, Charalambous S, Jani I, Bhatt N, Kampmann B, Sutherland J, Ntinginya NE, Evans D, Lönnroth K, Niemann S, Schaible UE, Geldmacher C, Sanne I, Hoelscher M, Churchyard G.

BMC Pulm Med. 2019 Jan 7;19(1):4. doi: 10.1186/s12890-018-0777-3.


Common left carotid bifurcation at C7-Th1 level: a rare anatomical variant.

Charalambous S, Hatzidakis A, Peteinarakis I, Megremis S, Karantanas A.

Surg Radiol Anat. 2019 Feb;41(2):227-229. doi: 10.1007/s00276-018-2140-z. Epub 2018 Nov 24.


Giant internal iliac artery aneurysm successfully treated with endovascular stent-graft placement.

Hatzidakis A, Touloupakis E, Charalambous S, Reppa D, Karagiannakidis E.

Interv Med Appl Sci. 2018 Mar;10(1):54-58. doi: 10.1556/1646.10.2018.04.


Do Incarcerated Populations Serve as a Reservoir for Tuberculosis in South Africa?

Sharp A, Donahoe JT, Milliken A, Barocio J, Charalambous S, McLaren ZM.

Am J Trop Med Hyg. 2018 Dec;99(6):1390-1396. doi: 10.4269/ajtmh.17-0652. Epub 2018 Sep 27.


Cost of point-of-care lateral flow urine lipoarabinomannan antigen testing in HIV-positive adults in South Africa.

Mukora R, Tlali M, Monkwe S, Charalambous S, Karat AS, Fielding KL, Grant AD, Vassall A.

Int J Tuberc Lung Dis. 2018 Sep 1;22(9):1082-1087. doi: 10.5588/ijtld.18.0046.


Enhancing value and lowering costs of care: a qualitative exploration of a randomized linkage to care intervention in South Africa.

Jain K, Mshweshwe-Pakela NT, Charalambous S, Mabuto T, Hoffmann CJ.

AIDS Care. 2019 Apr;31(4):481-488. doi: 10.1080/09540121.2018.1503636. Epub 2018 Aug 5.


Empirical estimation of resource constraints for use in model-based economic evaluation: an example of TB services in South Africa.

Bozzani FM, Mudzengi D, Sumner T, Gomez GB, Hippner P, Cardenas V, Charalambous S, White R, Vassall A.

Cost Eff Resour Alloc. 2018 Jul 30;16:27. doi: 10.1186/s12962-018-0113-z. eCollection 2018.


An intervention to optimise the delivery of integrated tuberculosis and HIV services at primary care clinics: results of the MERGE cluster randomised trial.

Kufa T, Fielding KL, Hippner P, Kielmann K, Vassall A, Churchyard GJ, Grant AD, Charalambous S.

Contemp Clin Trials. 2018 Sep;72:43-52. doi: 10.1016/j.cct.2018.07.013. Epub 2018 Jul 25.


Effectiveness of an "Exclusive Intervention Strategy" to increase medical male circumcision uptake among men aged 25-49 years in South Africa.

Grund JM, Chetty-Makkan CM, Ginindza S, Munyai R, Kisbey-Green H, Maraisane M, Charalambous S.

BMC Public Health. 2018 Jul 13;18(1):868. doi: 10.1186/s12889-018-5729-6.


Performance of verbal autopsy methods in estimating HIV-associated mortality among adults in South Africa.

Karat AS, Maraba N, Tlali M, Charalambous S, Chihota VN, Churchyard GJ, Fielding KL, Hanifa Y, Johnson S, McCarthy KM, Kahn K, Chandramohan D, Grant AD.

BMJ Glob Health. 2018 Jul 3;3(4):e000833. doi: 10.1136/bmjgh-2018-000833. eCollection 2018.


Evidence-informed policy making at country level: lessons learned from the South African Tuberculosis Think Tank.

White RG, Charalambous S, Cardenas V, Hippner P, Sumner T, Bozzani F, Mudzengi D, Houben RMGJ, Collier D, Kimerling ME, Vassall A, Pillay Y, Churchyard G.

Int J Tuberc Lung Dis. 2018 Jun 1;22(6):606-613. doi: 10.5588/ijtld.17.0485.


Perceptions of Value and Cost of HIV Care Engagement Following Diagnosis in South Africa.

Mabuto T, Charalambous S, Kennedy C, Hoffmann CJ.

AIDS Behav. 2018 Nov;22(11):3751-3762. doi: 10.1007/s10461-018-2089-2.


Household point of care CD4 testing and isoniazid preventive therapy initiation in a household TB contact tracing programme in two districts of South Africa.

Page-Shipp L, Lewis JJ, Velen K, Senoge S, Zishiri E, Popane F, Chihota VN, Clark D, Churchyard GJ, Charalambous S.

PLoS One. 2018 Mar 2;13(3):e0192089. doi: 10.1371/journal.pone.0192089. eCollection 2018.


Depression and alcohol use disorder at antiretroviral therapy initiation led to disengagement from care in South Africa.

Cichowitz C, Maraba N, Hamilton R, Charalambous S, Hoffmann CJ.

PLoS One. 2017 Dec 27;12(12):e0189820. doi: 10.1371/journal.pone.0189820. eCollection 2017.


The association between social capital and HIV treatment outcomes in South Africa.

Mukoswa GM, Charalambous S, Nelson G.

PLoS One. 2017 Nov 9;12(11):e0184140. doi: 10.1371/journal.pone.0184140. eCollection 2017.


Tuberculosis among HIV-infected population: incidence and risk factors in rural Tanzania.

Said K, Verver S, Kalingonji A, Lwilla F, Mkopi A, Charalambous S, Reither K.

Afr Health Sci. 2017 Mar;17(1):208-215. doi: 10.4314/ahs.v17i1.26.


Factors Associated With Poor Linkage to HIV Care in South Africa: Secondary Analysis of Data From the Thol'impilo Trial.

Dorward J, Mabuto T, Charalambous S, Fielding KL, Hoffmann CJ.

J Acquir Immune Defic Syndr. 2017 Dec 15;76(5):453-460. doi: 10.1097/QAI.0000000000001550.


A clinical scoring system to prioritise investigation for tuberculosis among adults attending HIV clinics in South Africa.

Hanifa Y, Fielding KL, Chihota VN, Adonis L, Charalambous S, Foster N, Karstaedt A, McCarthy K, Nicol MP, Ndlovu NT, Sinanovic E, Sahid F, Stevens W, Vassall A, Churchyard GJ, Grant AD.

PLoS One. 2017 Aug 3;12(8):e0181519. doi: 10.1371/journal.pone.0181519. eCollection 2017.


Strategies to Accelerate HIV Care and Antiretroviral Therapy Initiation After HIV Diagnosis: A Randomized Trial.

Hoffmann CJ, Mabuto T, Ginindza S, Fielding KL, Kubeka G, Dowdy DW, Churchyard GJ, Charalambous S.

J Acquir Immune Defic Syndr. 2017 Aug 15;75(5):540-547. doi: 10.1097/QAI.0000000000001428.


Measuring mortality due to HIV-associated tuberculosis among adults in South Africa: Comparing verbal autopsy, minimally-invasive autopsy, and research data.

Karat AS, Tlali M, Fielding KL, Charalambous S, Chihota VN, Churchyard GJ, Hanifa Y, Johnson S, McCarthy K, Martinson NA, Omar T, Kahn K, Chandramohan D, Grant AD.

PLoS One. 2017 Mar 23;12(3):e0174097. doi: 10.1371/journal.pone.0174097. eCollection 2017.


High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial.

Boeree MJ, Heinrich N, Aarnoutse R, Diacon AH, Dawson R, Rehal S, Kibiki GS, Churchyard G, Sanne I, Ntinginya NE, Minja LT, Hunt RD, Charalambous S, Hanekom M, Semvua HH, Mpagama SG, Manyama C, Mtafya B, Reither K, Wallis RS, Venter A, Narunsky K, Mekota A, Henne S, Colbers A, van Balen GP, Gillespie SH, Phillips PPJ, Hoelscher M; PanACEA consortium.

Lancet Infect Dis. 2017 Jan;17(1):39-49. doi: 10.1016/S1473-3099(16)30274-2. Epub 2016 Oct 26.


Effective Interpersonal Health Communication for Linkage to Care After HIV Diagnosis in South Africa.

Mabuto T, Charalambous S, Hoffmann CJ.

J Acquir Immune Defic Syndr. 2017 Jan 1;74 Suppl 1:S23-S28.


Eroded Tape: A Case of an Early Vesicoscopy Rather Than Laser Melting.

Grange P, Kouriefs C, Georgiades F, Charalambous S, Robinson D, Cardozo L.

Urology. 2017 Apr;102:247-251. doi: 10.1016/j.urology.2016.09.068. Epub 2016 Nov 18.


Autopsy Prevalence of Tuberculosis and Other Potentially Treatable Infections among Adults with Advanced HIV Enrolled in Out-Patient Care in South Africa.

Karat AS, Omar T, von Gottberg A, Tlali M, Chihota VN, Churchyard GJ, Fielding KL, Johnson S, Martinson NA, McCarthy K, Wolter N, Wong EB, Charalambous S, Grant AD.

PLoS One. 2016 Nov 9;11(11):e0166158. doi: 10.1371/journal.pone.0166158. eCollection 2016.


Verbal autopsy-assigned causes of death among adults being investigated for TB in South Africa.

Maraba N, Karat AS, McCarthy K, Churchyard GJ, Charalambous S, Kahn K, Grant AD, Chihota V.

Trans R Soc Trop Med Hyg. 2016 Sep;110(9):510-516. Epub 2016 Oct 7.


Outcomes of on-site antiretroviral therapy provision in a South African correctional facility.

Telisinghe L, Hippner P, Churchyard GJ, Gresak G, Grant AD, Charalambous S, Fielding KL.

Int J STD AIDS. 2016 Nov;27(13):1153-1161. Epub 2015 May 4.


Cost-effectiveness and resource implications of aggressive action on tuberculosis in China, India, and South Africa: a combined analysis of nine models.

Menzies NA, Gomez GB, Bozzani F, Chatterjee S, Foster N, Baena IG, Laurence YV, Qiang S, Siroka A, Sweeney S, Verguet S, Arinaminpathy N, Azman AS, Bendavid E, Chang ST, Cohen T, Denholm JT, Dowdy DW, Eckhoff PA, Goldhaber-Fiebert JD, Handel A, Huynh GH, Lalli M, Lin HH, Mandal S, McBryde ES, Pandey S, Salomon JA, Suen SC, Sumner T, Trauer JM, Wagner BG, Whalen CC, Wu CY, Boccia D, Chadha VK, Charalambous S, Chin DP, Churchyard G, Daniels C, Dewan P, Ditiu L, Eaton JW, Grant AD, Hippner P, Hosseini M, Mametja D, Pretorius C, Pillay Y, Rade K, Sahu S, Wang L, Houben RMGJ, Kimerling ME, White RG, Vassall A.

Lancet Glob Health. 2016 Nov;4(11):e816-e826. doi: 10.1016/S2214-109X(16)30265-0. Epub 2016 Oct 6.


Feasibility of achieving the 2025 WHO global tuberculosis targets in South Africa, China, and India: a combined analysis of 11 mathematical models.

Houben RMGJ, Menzies NA, Sumner T, Huynh GH, Arinaminpathy N, Goldhaber-Fiebert JD, Lin HH, Wu CY, Mandal S, Pandey S, Suen SC, Bendavid E, Azman AS, Dowdy DW, Bacaër N, Rhines AS, Feldman MW, Handel A, Whalen CC, Chang ST, Wagner BG, Eckhoff PA, Trauer JM, Denholm JT, McBryde ES, Cohen T, Salomon JA, Pretorius C, Lalli M, Eaton JW, Boccia D, Hosseini M, Gomez GB, Sahu S, Daniels C, Ditiu L, Chin DP, Wang L, Chadha VK, Rade K, Dewan P, Hippner P, Charalambous S, Grant AD, Churchyard G, Pillay Y, Mametja LD, Kimerling ME, Vassall A, White RG.

Lancet Glob Health. 2016 Nov;4(11):e806-e815. doi: 10.1016/S2214-109X(16)30199-1. Epub 2016 Oct 6.


HIV and tuberculosis in prisons in sub-Saharan Africa.

Telisinghe L, Charalambous S, Topp SM, Herce ME, Hoffmann CJ, Barron P, Schouten EJ, Jahn A, Zachariah R, Harries AD, Beyrer C, Amon JJ.

Lancet. 2016 Sep 17;388(10050):1215-27. doi: 10.1016/S0140-6736(16)30578-5. Epub 2016 Jul 14. Review.


Delivering PrePex Medical Male Circumcision Services Through a Mobile Clinic: The Experience From a Pilot Project in North West Province, South Africa.

Kufa T, Chetty-Makkan C, Maraisane M, Charalambous S, Chihota V, Toledo C.

J Acquir Immune Defic Syndr. 2016 Jun 1;72 Suppl 1:S69-72. doi: 10.1097/QAI.0000000000000798.


The incidence of tuberculosis among hiv-positive individuals with high CD4 counts: implications for policy.

Kufa T, Chihota V, Mngomezulu V, Charalambous S, Verver S, Churchyard G, Borgdorff M.

BMC Infect Dis. 2016 Jun 10;16:266. doi: 10.1186/s12879-016-1598-8.


Diagnostic Accuracy of Lateral Flow Urine LAM Assay for TB Screening of Adults with Advanced Immunosuppression Attending Routine HIV Care in South Africa.

Hanifa Y, Fielding KL, Chihota VN, Adonis L, Charalambous S, Karstaedt A, McCarthy K, Nicol MP, Ndlovu NT, Sahid F, Churchyard GJ, Grant AD.

PLoS One. 2016 Jun 7;11(6):e0156866. doi: 10.1371/journal.pone.0156866. eCollection 2016.


Household HIV Testing Uptake among Contacts of TB Patients in South Africa.

Velen K, Lewis JJ, Charalambous S, Page-Shipp L, Popane F, Churchyard GJ, Hoffmann CJ.

PLoS One. 2016 May 19;11(5):e0155688. doi: 10.1371/journal.pone.0155688. eCollection 2016.


Chronic hepatitis B increases mortality and complexity among HIV-coinfected patients in South Africa: a cohort study.

Velen K, Charalambous S, Innes C, Churchyard GJ, Hoffmann CJ.

HIV Med. 2016 Oct;17(9):702-7. doi: 10.1111/hiv.12367. Epub 2016 Mar 17.


Understanding healthcare and population mobility in southern Africa: The case of South Africa.

Walls HL, Vearey J, Modisenyane M, Chetty-Makkan CM, Charalambous S, Smith RD, Hanefeld J.

S Afr Med J. 2015 Nov 24;106(1):14-5. doi: 10.7196/SAMJ.2016.v106i1.10210. No abstract available.


Clinic-level factors influencing patient outcomes on antiretroviral therapy in primary health clinics in South Africa.

Charalambous S, Grant AD, Churchyard GJ, Mukora R, Schneider H, Fielding KL.

AIDS. 2016 Apr 24;30(7):1099-109. doi: 10.1097/QAD.0000000000001014.


The diagnostic accuracy of urine lipoarabinomannan test for tuberculosis screening in a South African correctional facility.

Hanifa Y, Telisinghe L, Fielding KL, Malden JL, Churchyard GJ, Grant AD, Charalambous S.

PLoS One. 2015 May 26;10(5):e0127956. doi: 10.1371/journal.pone.0127956. eCollection 2015.


Implementing a large-scale systematic tuberculosis screening program in correctional facilities in South Africa.

Zishiri V, Charalambous S, Shah MR, Chihota V, Page-Shipp L, Churchyard GJ, Hoffmann CJ.

Open Forum Infect Dis. 2015 Jan 8;2(1):ofu121. doi: 10.1093/ofid/ofu121. eCollection 2015 Jan.


Tuberculosis active case finding: uptake and diagnostic yield among minibus drivers in urban South Africa.

Mabuto T, Zwane E, Chihota V, Gresak G, Charalambous S, Churchyard GJ, Hoffmann CJ.

BMC Public Health. 2015 Mar 14;15:242. doi: 10.1186/s12889-015-1592-x.


Evaluation of a point-of-care tuberculosis test-and-treat algorithm on early mortality in people with HIV accessing antiretroviral therapy (TB Fast Track study): study protocol for a cluster randomised controlled trial.

Fielding KL, Charalambous S, Hoffmann CJ, Johnson S, Tlali M, Dorman SE, Vassall A, Churchyard GJ, Grant AD.

Trials. 2015 Mar 28;16:125. doi: 10.1186/s13063-015-0650-0.


Pooling sputum from multiple individuals for Xpert® MTB/RIF testing: a strategy for screening high-risk populations.

Zishiri V, Chihota V, McCarthy K, Charalambous S, Churchyard GJ, Hoffmann CJ.

Int J Tuberc Lung Dis. 2015 Jan;19(1):87-90. doi: 10.5588/ijtld.14.0372.


Impact of drug resistance-associated amino acid changes in HIV-1 subtype C on susceptibility to newer nonnucleoside reverse transcriptase inhibitors.

Basson AE, Rhee SY, Parry CM, El-Khatib Z, Charalambous S, De Oliveira T, Pillay D, Hoffmann C, Katzenstein D, Shafer RW, Morris L.

Antimicrob Agents Chemother. 2015 Feb;59(2):960-71. doi: 10.1128/AAC.04215-14. Epub 2014 Nov 24.


Incidence of HIV-associated tuberculosis among individuals taking combination antiretroviral therapy: a systematic review and meta-analysis.

Kufa T, Mabuto T, Muchiri E, Charalambous S, Rosillon D, Churchyard G, Harris RC.

PLoS One. 2014 Nov 13;9(11):e111209. doi: 10.1371/journal.pone.0111209. eCollection 2014. Review.


High-dose rifapentine with moxifloxacin for pulmonary tuberculosis.

Jindani A, Harrison TS, Nunn AJ, Phillips PP, Churchyard GJ, Charalambous S, Hatherill M, Geldenhuys H, McIlleron HM, Zvada SP, Mungofa S, Shah NA, Zizhou S, Magweta L, Shepherd J, Nyirenda S, van Dijk JH, Clouting HE, Coleman D, Bateson AL, McHugh TD, Butcher PD, Mitchison DA; RIFAQUIN Trial Team.

N Engl J Med. 2014 Oct 23;371(17):1599-608. doi: 10.1056/NEJMoa1314210.


A cluster randomised trial to evaluate the effect of optimising TB/HIV integration on patient level outcomes: the "merge" trial protocol.

Kufa T, Hippner P, Charalambous S, Kielmann K, Vassall A, Churchyard GJ, Grant AD, Fielding KL.

Contemp Clin Trials. 2014 Nov;39(2):280-7. doi: 10.1016/j.cct.2014.10.003. Epub 2014 Oct 12.


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