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Items: 1 to 50 of 249

1.

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.

Sartori M, Mendes T, Desai S, Lasorsa A, Herledan A, Malmanche N, Mäkinen P, Marttinen M, Malki I, Chapuis J, Flaig A, Vreulx AC, Ciancia M, Amouyel P, Leroux F, Déprez B, Cantrelle FX, Maréchal D, Pradier L, Hiltunen M, Landrieu I, Kilinc D, Herault Y, Laporte J, Lambert JC.

Acta Neuropathol. 2019 May 7. doi: 10.1007/s00401-019-02017-9. [Epub ahead of print]

PMID:
31065832
2.

The new genetic landscape of Alzheimer's disease: from amyloid cascade to genetically driven synaptic failure hypothesis?

Dourlen P, Kilinc D, Malmanche N, Chapuis J, Lambert JC.

Acta Neuropathol. 2019 Apr 13. doi: 10.1007/s00401-019-02004-0. [Epub ahead of print] Review.

PMID:
30982098
3.

British Red Squirrels Remain the Only Known Wild Rodent Host for Leprosy Bacilli.

Schilling AK, Avanzi C, Ulrich RG, Busso P, Pisanu B, Ferrari N, Romeo C, Mazzamuto MV, McLuckie J, Shuttleworth CM, Del-Pozo J, Lurz PWW, Escalante-Fuentes WG, Ocampo-Candiani J, Vera-Cabrera L, Stevenson K, Chapuis JL, Meredith AL, Cole ST.

Front Vet Sci. 2019 Feb 1;6:8. doi: 10.3389/fvets.2019.00008. eCollection 2019.

4.

Within- and between-year variations of reproductive strategy and cost in a population of Siberian chipmunks.

Le Coeur C, Pisanu B, Chapuis JL, Robert A.

Oecologia. 2018 Nov;188(3):765-776. doi: 10.1007/s00442-018-4259-3. Epub 2018 Sep 15.

PMID:
30219947
5.

Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS Signals.

Dourlen P, Chapuis J, Lambert JC.

Curr Genet Med Rep. 2018;6(3):107-115. doi: 10.1007/s40142-018-0141-1. Epub 2018 May 29. Review.

6.

Divergent in shape and convergent in function: Adaptive evolution of the mandible in Sub-Antarctic mice.

Renaud S, Ledevin R, Pisanu B, Chapuis JL, Quillfeldt P, Hardouin EA.

Evolution. 2018 Apr;72(4):878-892. doi: 10.1111/evo.13467. Epub 2018 Mar 25.

PMID:
29528493
7.

Antineoplastic Agents. 606. The Betulastatins.

Pettit GR, Melody N, Chapuis JC.

J Nat Prod. 2018 Mar 23;81(3):458-464. doi: 10.1021/acs.jnatprod.7b00536. Epub 2018 Jan 5.

PMID:
29303263
8.

Antineoplastic Agents. 605. Isoquinstatins.

Pettit GR, Melody N, Chapuis JC.

J Nat Prod. 2018 Mar 23;81(3):451-457. doi: 10.1021/acs.jnatprod.7b00352. Epub 2017 Sep 19.

PMID:
28926240
9.

Antineoplastic Agents. 604. The Path of Quinstatin Derivatives to Antibody Drug Conjugates.

Pettit GR, Melody N, Chapuis JC.

J Nat Prod. 2017 Sep 22;80(9):2447-2452. doi: 10.1021/acs.jnatprod.7b00237. Epub 2017 Sep 12.

PMID:
28895394
10.

1.15 PW-850 J compressed beam demonstration using the PETAL facility.

Blanchot N, Béhar G, Chapuis JC, Chappuis C, Chardavoine S, Charrier JF, Coïc H, Damiens-Dupont C, Duthu J, Garcia P, Goossens JP, Granet F, Grosset-Grange C, Guerin P, Hebrard B, Hilsz L, Lamaignere L, Lacombe T, Lavastre E, Longhi T, Luce J, Macias F, Mangeant M, Mazataud E, Minou B, Morgaint T, Noailles S, Neauport J, Patelli P, Perrot-Minnot E, Present C, Remy B, Rouyer C, Santacreu N, Sozet M, Valla D, Laniesse F.

Opt Express. 2017 Jul 24;25(15):16957-16970. doi: 10.1364/OE.25.016957.

PMID:
28789195
11.

A stretch of residues within the protease-resistant core is not necessary for prion structure and infectivity.

Munoz-Montesino C, Sizun C, Moudjou M, Herzog L, Reine F, Igel-Egalon A, Barbereau C, Chapuis J, Ciric D, Laude H, Béringue V, Rezaei H, Dron M.

Prion. 2017 Jan 2;11(1):25-30. doi: 10.1080/19336896.2016.1274851. Epub 2017 Feb 8.

12.

Antineoplastic Agents. 603. Quinstatins: Exceptional Cancer Cell Growth Inhibitors.

Pettit GR, Melody N, Chapuis JC.

J Nat Prod. 2017 Mar 24;80(3):692-698. doi: 10.1021/acs.jnatprod.6b01006. Epub 2017 Feb 17.

PMID:
28211277
13.

[in process].

Chapuis J.

Krankenpfl Soins Infirm. 2017;110(4):80. Italian. No abstract available.

PMID:
30299626
14.

[in process].

Chapuis J.

Krankenpfl Soins Infirm. 2017;110(4):62. French. No abstract available.

PMID:
30299619
15.

[in process].

Chapuis J.

Krankenpfl Soins Infirm. 2017;110(4):15. German. No abstract available.

PMID:
30299604
16.

Proximity Ligation Assay: A Tool to Study Endogenous Interactions Between Tau and Its Neuronal Partners.

Bretteville A, Demiautte F, Chapuis J.

Methods Mol Biol. 2017;1523:297-305.

PMID:
27975258
17.

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.

Chapuis J, Flaig A, Grenier-Boley B, Eysert F, Pottiez V, Deloison G, Vandeputte A, Ayral AM, Mendes T, Desai S, Goate AM, Kauwe JSK, Leroux F, Herledan A, Demiautte F, Bauer C, Checler F, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Albert M, Moghekar A, O'Brien R, Peskind ER, Malmanche N, Schellenberg GD, Dourlen P, Song OR, Cruchaga C, Amouyel P, Deprez B, Brodin P, Lambert JC; ADGC, Alzheimer’s Disease Neuroimaging Initiative.

Acta Neuropathol. 2017 Jun;133(6):955-966. doi: 10.1007/s00401-016-1652-z. Epub 2016 Dec 8.

18.

Multiple independent transmission cycles of a tick-borne pathogen within a local host community.

Jacquot M, Abrial D, Gasqui P, Bord S, Marsot M, Masseglia S, Pion A, Poux V, Zilliox L, Chapuis JL, Vourc'h G, Bailly X.

Sci Rep. 2016 Aug 8;6:31273. doi: 10.1038/srep31273.

19.

Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification.

Moudjou M, Chapuis J, Mekrouti M, Reine F, Herzog L, Sibille P, Laude H, Vilette D, Andréoletti O, Rezaei H, Dron M, Béringue V.

Sci Rep. 2016 Jul 7;6:29116. doi: 10.1038/srep29116.

20.

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease.

Letronne F, Laumet G, Ayral AM, Chapuis J, Demiautte F, Laga M, Vandenberghe ME, Malmanche N, Leroux F, Eysert F, Sottejeau Y, Chami L, Flaig A, Bauer C, Dourlen P, Lesaffre M, Delay C, Huot L, Dumont J, Werkmeister E, Lafont F, Mendes T, Hansmannel F, Dermaut B, Deprez B, Hérard AS, Dhenain M, Souedet N, Pasquier F, Tulasne D, Berr C, Hauw JJ, Lemoine Y, Amouyel P, Mann D, Déprez R, Checler F, Hot D, Delzescaux T, Gevaert K, Lambert JC.

EBioMedicine. 2016 Jul;9:278-292. doi: 10.1016/j.ebiom.2016.06.002. Epub 2016 Jun 2.

21.

Generating Bona Fide Mammalian Prions with Internal Deletions.

Munoz-Montesino C, Sizun C, Moudjou M, Herzog L, Reine F, Chapuis J, Ciric D, Igel-Egalon A, Laude H, Béringue V, Rezaei H, Dron M.

J Virol. 2016 Jul 11;90(15):6963-6975. doi: 10.1128/JVI.00555-16. Print 2016 Aug 1.

22.

Isolation and Structure of Cancer Cell Growth Inhibitory Tetracyclic Triterpenoids from the Zimbabwean Monadenium lugardae.

Pettit GR, Ye Q, Herald DL, Knight JC, Hogan F, Melody N, Mukku VJ, Doubek DL, Chapuis JC.

J Nat Prod. 2016 Jun 24;79(6):1598-603. doi: 10.1021/acs.jnatprod.6b00107. Epub 2016 May 23.

PMID:
27214528
23.

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.

Dourlen P, Fernandez-Gomez FJ, Dupont C, Grenier-Boley B, Bellenguez C, Obriot H, Caillierez R, Sottejeau Y, Chapuis J, Bretteville A, Abdelfettah F, Delay C, Malmanche N, Soininen H, Hiltunen M, Galas MC, Amouyel P, Sergeant N, Buée L, Lambert JC, Dermaut B.

Mol Psychiatry. 2017 Jun;22(6):874-883. doi: 10.1038/mp.2016.59. Epub 2016 Apr 26.

24.

Inter-annual and inter-individual variations in survival exhibit strong seasonality in a hibernating rodent.

Le Cœur C, Chantepie S, Pisanu B, Chapuis JL, Robert A.

Oecologia. 2016 Jul;181(3):795-807. doi: 10.1007/s00442-016-3597-2. Epub 2016 Mar 11.

PMID:
26969470
25.

Antineoplastic Agents. 585. Isolation of Bridelia ferruginea Anticancer Podophyllotoxins and Synthesis of 4-Aza-podophyllotoxin Structural Modifications.

Pettit GR, Searcy JD, Tan R, Cragg GM, Melody N, Knight JC, Chapuis JC.

J Nat Prod. 2016 Mar 25;79(3):507-18. doi: 10.1021/acs.jnatprod.5b00873. Epub 2016 Mar 3.

PMID:
26938998
26.

Mapping human risk of infection with Borrelia burgdorferi sensu lato, the agent of Lyme borreliosis, in a periurban forest in France.

Vourc'h G, Abrial D, Bord S, Jacquot M, Masséglia S, Poux V, Pisanu B, Bailly X, Chapuis JL.

Ticks Tick Borne Dis. 2016 Jul;7(5):644-652. doi: 10.1016/j.ttbdis.2016.02.008. Epub 2016 Feb 6.

PMID:
26897396
27.

Emergence of two prion subtypes in ovine PrP transgenic mice infected with human MM2-cortical Creutzfeldt-Jakob disease prions.

Chapuis J, Moudjou M, Reine F, Herzog L, Jaumain E, Chapuis C, Quadrio I, Boulliat J, Perret-Liaudet A, Dron M, Laude H, Rezaei H, Béringue V.

Acta Neuropathol Commun. 2016 Feb 5;4:10. doi: 10.1186/s40478-016-0284-9.

28.

Phylogeny and adaptation shape the teeth of insular mice.

Ledevin R, Chevret P, Ganem G, Britton-Davidian J, Hardouin EA, Chapuis JL, Pisanu B, da Luz Mathias M, Schlager S, Auffray JC, Renaud S.

Proc Biol Sci. 2016 Feb 10;283(1824). pii: 20152820. doi: 10.1098/rspb.2015.2820.

29.

Preventing species invasion: A role for integrative taxonomy?

Mazzamuto MV, Galimberti A, Cremonesi G, Pisanu B, Chapuis JL, Stuyck J, Amori G, Su H, Aloise G, Preatoni DG, Wauters LA, Casiraghi M, Martinoli A.

Integr Zool. 2016 May;11(3):214-28. doi: 10.1111/1749-4877.12185.

PMID:
26748591
30.

Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domain.

Sottejeau Y, Bretteville A, Cantrelle FX, Malmanche N, Demiaute F, Mendes T, Delay C, Alves Dos Alves H, Flaig A, Davies P, Dourlen P, Dermaut B, Laporte J, Amouyel P, Lippens G, Chapuis J, Landrieu I, Lambert JC.

Acta Neuropathol Commun. 2015 Sep 23;3:58. doi: 10.1186/s40478-015-0237-8.

31.

Association Between Infliximab Trough Levels and the Occurrence of Paradoxical Manifestations in Patients with Inflammatory Bowel Disease: a Case-Control Study.

Coutzac C, Chapuis J, Poullenot F, Chabrun E, Capdepont M, Blanco P, Laharie D.

J Crohns Colitis. 2015 Nov;9(11):982-7. doi: 10.1093/ecco-jcc/jjv159. Epub 2015 Sep 7.

PMID:
26351388
32.

Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie.

Sarradin P, Viglietta C, Limouzin C, Andréoletti O, Daniel-Carlier N, Barc C, Leroux-Coyau M, Berthon P, Chapuis J, Rossignol C, Gatti JL, Belghazi M, Labas V, Vilotte JL, Béringue V, Lantier F, Laude H, Houdebine LM.

PLoS Pathog. 2015 Aug 6;11(8):e1005077. doi: 10.1371/journal.ppat.1005077. eCollection 2015 Aug.

33.

The Cephalostatins. 24. Isolation, Structure, and Cancer Cell Growth Inhibition of Cephalostatin 20.

Pettit GR, Xu JP, Chapuis JC, Melody N.

J Nat Prod. 2015 Jun 26;78(6):1446-50. doi: 10.1021/acs.jnatprod.5b00129. Epub 2015 Jun 4.

PMID:
26042639
34.

The Cephalostatins. 23. Conversion of Hecogenin to a Steroidal 1,6-Dioxaspiro[5.5]nonane Analogue for Cephalostatin 11.

Pettit GR, Moser BR, Herald DL, Knight JC, Chapuis JC, Zheng X.

J Nat Prod. 2015 May 22;78(5):1067-72. doi: 10.1021/np501033u. Epub 2015 Apr 27.

PMID:
25915559
35.

Interaction between Shadoo and PrP Affects the PrP-Folding Pathway.

Ciric D, Richard CA, Moudjou M, Chapuis J, Sibille P, Daude N, Westaway D, Adrover M, Béringue V, Martin D, Rezaei H.

J Virol. 2015 Jun;89(12):6287-93. doi: 10.1128/JVI.03429-14. Epub 2015 Apr 8.

36.

Infection of Siberian chipmunks (Tamias sibiricus barberi) with Borrelia sp. reveals a low reservoir competence under experimental conditions.

Bonnet S, Choumet V, Masseglia S, Cote M, Ferquel E, Lilin T, Marsot M, Chapuis JL, Vourc'h G.

Ticks Tick Borne Dis. 2015 Apr;6(3):393-400. doi: 10.1016/j.ttbdis.2015.03.008. Epub 2015 Mar 21.

PMID:
25805623
37.

Seasonal variation in infestations by ixodids on Siberian chipmunks: effects of host age, sex, and birth season.

Le Coeur C, Robert A, Pisanu B, Chapuis JL.

Parasitol Res. 2015 Jun;114(6):2069-78. doi: 10.1007/s00436-015-4391-5. Epub 2015 Mar 1.

PMID:
25724565
38.

Antineoplastic agents. 599. Total synthesis of dolastatin 16.

Pettit GR, Smith TH, Arce PM, Flahive EJ, Anderson CR, Chapuis JC, Xu JP, Groy TL, Belcher PE, Macdonald CB.

J Nat Prod. 2015 Mar 27;78(3):476-85. doi: 10.1021/np500925y. Epub 2015 Feb 17.

PMID:
25689568
39.

Antineoplastic agents. 600. From the South Pacific Ocean to the silstatins.

Pettit GR, Arce PM, Chapuis JC, Macdonald CB.

J Nat Prod. 2015 Mar 27;78(3):510-23. doi: 10.1021/np501004h. Epub 2015 Feb 17.

PMID:
25688575
40.

Functional complementation in Drosophila to predict the pathogenicity of TARDBP variants: evidence for a loss-of-function mechanism.

Vanden Broeck L, Kleinberger G, Chapuis J, Gistelinck M, Amouyel P, Van Broeckhoven C, Lambert JC, Callaerts P, Dermaut B.

Neurobiol Aging. 2015 Feb;36(2):1121-9. doi: 10.1016/j.neurobiolaging.2014.09.001. Epub 2014 Sep 28.

PMID:
25442115
41.

A viable population of the European red squirrel in an urban park.

Rézouki C, Dozières A, Le Cœur C, Thibault S, Pisanu B, Chapuis JL, Baudry E.

PLoS One. 2014 Aug 15;9(8):e105111. doi: 10.1371/journal.pone.0105111. eCollection 2014.

42.

Antineoplastic agents. 595. Structural modifications of betulin and the X-ray crystal structure of an unusual betulin amine dimer.

Pettit GR, Melody N, Hempenstall F, Chapuis JC, Groy TL, Williams L.

J Nat Prod. 2014 Apr 25;77(4):863-72. doi: 10.1021/np400947d. Epub 2014 Apr 2.

43.

[The children of Virginia].

Chapuis J.

Krankenpfl Soins Infirm. 2014;107(1):56-61, 76-80. French, Italian. No abstract available.

PMID:
24575569
44.

A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly.

Chouraki V, De Bruijn RF, Chapuis J, Bis JC, Reitz C, Schraen S, Ibrahim-Verbaas CA, Grenier-Boley B, Delay C, Rogers R, Demiautte F, Mounier A, Fitzpatrick AL; Alzheimer's Disease Neuroimaging Initiative, Berr C, Dartigues JF, Uitterlinden AG, Hofman A, Breteler M, Becker JT, Lathrop M, Schupf N, Alpérovitch A, Mayeux R, van Duijn CM, Buée L, Amouyel P, Lopez OL, Ikram MA, Tzourio C, Lambert JC.

Mol Psychiatry. 2014 Dec;19(12):1326-35. doi: 10.1038/mp.2013.185. Epub 2014 Feb 18.

45.

High-throughput sequence typing reveals genetic differentiation and host specialization among populations of the Borrelia burgdorferi species complex that infect rodents.

Jacquot M, Bisseux M, Abrial D, Marsot M, Ferquel E, Chapuis JL, Vourc'h G, Bailly X.

PLoS One. 2014 Feb 12;9(2):e88581. doi: 10.1371/journal.pone.0088581. eCollection 2014.

46.

High prevalence of Borrelia burgdorferi s.l. in the European red squirrel Sciurus vulgaris in France.

Pisanu B, Chapuis JL, Dozières A, Basset F, Poux V, Vourc'h G.

Ticks Tick Borne Dis. 2014 Feb;5(1):1-6.

PMID:
24446554
47.

Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification.

Moudjou M, Sibille P, Fichet G, Reine F, Chapuis J, Herzog L, Jaumain E, Laferrière F, Richard CA, Laude H, Andréoletti O, Rezaei H, Béringue V.

MBio. 2013 Dec 31;5(1):e00829-13. doi: 10.1128/mBio.00829-13.

48.

Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics.

Laferrière F, Tixador P, Moudjou M, Chapuis J, Sibille P, Herzog L, Reine F, Jaumain E, Laude H, Rezaei H, Béringue V.

PLoS Pathog. 2013;9(10):e1003702. doi: 10.1371/journal.ppat.1003702. Epub 2013 Oct 10.

49.

Lateral entorhinal modulation of piriform cortical activity and fine odor discrimination.

Chapuis J, Cohen Y, He X, Zhang Z, Jin S, Xu F, Wilson DA.

J Neurosci. 2013 Aug 14;33(33):13449-59. doi: 10.1523/JNEUROSCI.1387-13.2013.

50.

Deciphering bartonella diversity, recombination, and host specificity in a rodent community.

Buffet JP, Pisanu B, Brisse S, Roussel S, Félix B, Halos L, Chapuis JL, Vayssier-Taussat M.

PLoS One. 2013 Jul 24;8(7):e68956. doi: 10.1371/journal.pone.0068956. Print 2013.

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