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Items: 18


A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex.

Partlow EA, Baker RW, Beacham GM, Chappie JS, Leschziner AE, Hollopeter G.

Elife. 2019 Aug 29;8. pii: e50003. doi: 10.7554/eLife.50003.


Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.

Schiltz CJ, Lee A, Partlow EA, Hosford CJ, Chappie JS.

Nucleic Acids Res. 2019 Sep 26;47(17):9448-9463. doi: 10.1093/nar/gkz703.


The structural biology of the dynamin-related proteins: New insights into a diverse, multitalented family.

Ford MGJ, Chappie JS.

Traffic. 2019 Oct;20(10):717-740. doi: 10.1111/tra.12676. Epub 2019 Aug 26. Review.


Endopeptidase Regulation as a Novel Function of the Zur-Dependent Zinc Starvation Response.

Murphy SG, Alvarez L, Adams MC, Liu S, Chappie JS, Cava F, Dörr T.

MBio. 2019 Feb 19;10(1). pii: e02620-18. doi: 10.1128/mBio.02620-18.


Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture.

Varlakhanova NV, Alvarez FJD, Brady TM, Tornabene BA, Hosford CJ, Chappie JS, Zhang P, Ford MGJ.

J Cell Biol. 2018 Oct 1;217(10):3608-3624. doi: 10.1083/jcb.201712021. Epub 2018 Aug 7.


The crystal structure of the Helicobacter pylori LlaJI.R1 N-terminal domain provides a model for site-specific DNA binding.

Hosford CJ, Chappie JS.

J Biol Chem. 2018 Jul 27;293(30):11758-11771. doi: 10.1074/jbc.RA118.001888. Epub 2018 Jun 12.


A dynamin mutant defines a superconstricted prefission state.

Sundborger AC, Fang S, Heymann JA, Ray P, Chappie JS, Hinshaw JE.

Cell Rep. 2014 Aug 7;8(3):734-42. doi: 10.1016/j.celrep.2014.06.054. Epub 2014 Jul 31.


Building a fission machine--structural insights into dynamin assembly and activation.

Chappie JS, Dyda F.

J Cell Sci. 2013 Jul 1;126(Pt 13):2773-84. doi: 10.1242/jcs.108845. Epub 2013 Jun 18. Review.


The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization.

Maggin JE, James JA, Chappie JS, Dyda F, Hickman AB.

J Virol. 2012 Mar;86(6):3337-46. doi: 10.1128/JVI.06775-11. Epub 2011 Dec 28.


A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke.

Chappie JS, Mears JA, Fang S, Leonard M, Schmid SL, Milligan RA, Hinshaw JE, Dyda F.

Cell. 2011 Sep 30;147(1):209-22. doi: 10.1016/j.cell.2011.09.003.


Helical crystallization of soluble and membrane binding proteins.

Wilson-Kubalek EM, Chappie JS, Arthur CP.

Methods Enzymol. 2010;481:45-62. doi: 10.1016/S0076-6879(10)81002-X.


G domain dimerization controls dynamin's assembly-stimulated GTPase activity.

Chappie JS, Acharya S, Leonard M, Schmid SL, Dyda F.

Nature. 2010 May 27;465(7297):435-40. doi: 10.1038/nature09032. Epub 2010 Apr 28.


An intramolecular signaling element that modulates dynamin function in vitro and in vivo.

Chappie JS, Acharya S, Liu YW, Leonard M, Pucadyil TJ, Schmid SL.

Mol Biol Cell. 2009 Aug;20(15):3561-71. doi: 10.1091/mbc.E09-04-0318. Epub 2009 Jun 10.


Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles.

Littlefield KP, Ward AB, Chappie JS, Reedy MK, Bernstein SI, Milligan RA, Reedy MC.

J Mol Biol. 2008 Sep 5;381(3):519-28. doi: 10.1016/j.jmb.2008.06.029. Epub 2008 Jun 17.


The dynamin middle domain is critical for tetramerization and higher-order self-assembly.

Ramachandran R, Surka M, Chappie JS, Fowler DM, Foss TR, Song BD, Schmid SL.

EMBO J. 2007 Jan 24;26(2):559-66. Epub 2006 Dec 14.


The conserved KMN network constitutes the core microtubule-binding site of the kinetochore.

Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A.

Cell. 2006 Dec 1;127(5):983-97.


The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases.

Chappie JS, Cànaves JM, Han GW, Rife CL, Xu Q, Stevens RC.

Structure. 2005 Sep;13(9):1385-96.


Electrostatic tuning of ion conductance in potassium channels.

Nimigean CM, Chappie JS, Miller C.

Biochemistry. 2003 Aug 12;42(31):9263-8.


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