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Items: 17


Dual muscle-liver transduction imposes immune tolerance for muscle transgene engraftment despite preexisting immunity.

Bartolo L, Li Chung Tong S, Chappert P, Urbain D, Collaud F, Colella P, Richard I, Ronzitti G, Demengeot J, Gross DA, Mingozzi F, Davoust J.

JCI Insight. 2019 Jun 6;4(11). pii: 127008. doi: 10.1172/jci.insight.127008. eCollection 2019 Jun 6.


Foxp3+ Regulatory and Conventional CD4+ T Cells Display Similarly High Frequencies of Alloantigen-Reactive Cells.

Lalfer M, Chappert P, Carpentier M, Urbain D, Davoust JM, Gross DA.

Front Immunol. 2019 Mar 19;10:521. doi: 10.3389/fimmu.2019.00521. eCollection 2019.


Induction of tumor-specific CTL responses using the C-terminal fragment of Viral protein R as cell penetrating peptide.

Gross DA, Leborgne C, Chappert P, Masurier C, Leboeuf M, Monteilhet V, Boutin S, Lemonnier FA, Davoust J, Kichler A.

Sci Rep. 2019 Mar 8;9(1):3937. doi: 10.1038/s41598-019-40594-7.


Cross-Presentation of Skin-Targeted Recombinant Adeno-associated Virus 2/1 Transgene Induces Potent Resident Memory CD8+ T Cell Responses.

Gross DA, Ghenassia A, Bartolo L, Urbain D, Benkhelifa-Ziyyat S, Lorain S, Davoust J, Chappert P.

J Virol. 2019 Feb 19;93(5). pii: e01334-18. doi: 10.1128/JVI.01334-18. Print 2019 Mar 1.


A hierarchy of affinities between cytokine receptors and the common gamma chain leads to pathway cross-talk.

Gonnord P, Angermann BR, Sadtler K, Gombos E, Chappert P, Meier-Schellersheim M, Varma R.

Sci Signal. 2018 Apr 3;11(524). pii: eaal1253. doi: 10.1126/scisignal.aal1253.


Intradermal Immunization with rAAV1 Vector Induces Robust Memory CD8+ T Cell Responses Independently of Transgene Expression in DCs.

Ghenassia A, Gross DA, Lorain S, Tros F, Urbain D, Benkhelifa-Ziyyat S, Charbit A, Davoust J, Chappert P.

Mol Ther. 2017 Oct 4;25(10):2309-2322. doi: 10.1016/j.ymthe.2017.06.019. Epub 2017 Jul 15.


Correction: Depletion of Regulatory T Cells Induces High Numbers of Dendritic Cells and Unmasks a Subset of Anti-Tumour CD8+CD11c+ PD-1lo Effector T Cells.

Goudin N, Chappert P, Mégret J, Gross DA, Rocha B, Azogui O.

PLoS One. 2017 Jan 27;12(1):e0171373. doi: 10.1371/journal.pone.0171373. eCollection 2017.


Depletion of Regulatory T Cells Induces High Numbers of Dendritic Cells and Unmasks a Subset of Anti-Tumour CD8+CD11c+ PD-1lo Effector T Cells.

Goudin N, Chappert P, Mégret J, Gross DA, Rocha B, Azogui O.

PLoS One. 2016 Jun 24;11(6):e0157822. doi: 10.1371/journal.pone.0157822. eCollection 2016. Erratum in: PLoS One. 2017 Jan 27;12 (1):e0171373.


Intrinsic transgene immunogenicity gears CD8(+) T-cell priming after rAAV-mediated muscle gene transfer.

Carpentier M, Lorain S, Chappert P, Lalfer M, Hardet R, Urbain D, Peccate C, Adriouch S, Garcia L, Davoust J, Gross DA.

Mol Ther. 2015 Apr;23(4):697-706. doi: 10.1038/mt.2014.235. Epub 2014 Dec 10.


Role of SFB in autoimmune arthritis: an example of regulation of autoreactive T cell sensitivity in the gut.

Chappert P.

Gut Microbes. 2014 Mar-Apr;5(2):259-64. doi: 10.4161/gmic.28134. Epub 2014 Feb 6.


Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentation.

Ravindran R, Khan N, Nakaya HI, Li S, Loebbermann J, Maddur MS, Park Y, Jones DP, Chappert P, Davoust J, Weiss DS, Virgin HW, Ron D, Pulendran B.

Science. 2014 Jan 17;343(6168):313-317. doi: 10.1126/science.1246829. Epub 2013 Dec 5.


Extrathymic induction of Foxp3⁺ regulatory T cells declines with age in a T-cell intrinsic manner.

Carpentier M, Chappert P, Kuhn C, Lalfer M, Flament H, Burlen-Defranoux O, Lantz O, Bandeira A, Malissen B, Davoust J, Gross DA.

Eur J Immunol. 2013 Oct;43(10):2598-604. doi: 10.1002/eji.201343532. Epub 2013 Jul 31.


Specific gut commensal flora locally alters T cell tuning to endogenous ligands.

Chappert P, Bouladoux N, Naik S, Schwartz RH.

Immunity. 2013 Jun 27;38(6):1198-210. doi: 10.1016/j.immuni.2013.06.005.


Induction of T cell anergy: integration of environmental cues and infectious tolerance.

Chappert P, Schwartz RH.

Curr Opin Immunol. 2010 Oct;22(5):552-9. doi: 10.1016/j.coi.2010.08.005. Epub 2010 Sep 24. Review.


Antigen-specific Treg impair CD8(+) T-cell priming by blocking early T-cell expansion.

Chappert P, Leboeuf M, Rameau P, Lalfer M, Desbois S, Liblau RS, Danos O, Davoust JM, Gross DA.

Eur J Immunol. 2010 Feb;40(2):339-50. doi: 10.1002/eji.200839107.


Antigen-driven interactions with dendritic cells and expansion of Foxp3+ regulatory T cells occur in the absence of inflammatory signals.

Chappert P, Leboeuf M, Rameau P, Stockholm D, Liblau R, Danos O, Davoust JM, Gross DA.

J Immunol. 2008 Jan 1;180(1):327-34.


Simple conditioning with monospecific CD4+CD25+ regulatory T cells for bone marrow engraftment and tolerance to multiple gene products.

Gross DA, Chappert P, Leboeuf M, Monteilhet V, Van Wittenberghe L, Danos O, Davoust J.

Blood. 2006 Sep 15;108(6):1841-8. Epub 2006 Jun 1.

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